CA2700727A1 - Complex product with advanced assimilation efficacy for humans and its utilization - Google Patents

Abstract

For the manufacturing of a complex product with advanced assimilation efficacy, including methyl-methionine sul-phonium, carboxyl-uracil, paraaminobenzoic acid, dimethyl-sulfoxide and poliethoxy castor oil, and its utilization.

Description

Complex Product with Advanced Assimilation Efficacy for Humans and its Utilization We created our invention with the aim of restoring the appropriate level of food supply that has become reduced or insufficient due to viral-, bacterial-, fungal infections, harmful environmental emissions causing, amongst others, pollen-, and dust allergies, along with radiation-, and chemotherapy treatments, surgeries, UV-, X-ray and radioactive rays.

Also, the aim of the inventon is to improve the assimilation of food that has become insufficient due to ageing as well as the harmful multiple effects caused during the process of natural ageing.

In order for us to achieve these goals, the objective of our invention is to develop and implement the simplest possible procedure that is feasible with ease.

The product, in accordance with the innovation, consists of water-soluble methyl-methionine sulphonium iodide and paraaminobenzoic acid as well as fat-soluble carboxyl-uracil along with a unique emulsion system belonging to the latter to make it water-soluble without limitation.

To produce this emulsion, the invention uses poliethoxy castor oil (ChremophorR EL, BASF) degraded during the metabolism and dimethyl-sulfoxide, thus making the use of the product of the invention possible for humans.

This product is assimilated in the form of water-soluble substance through the intestines, and contains no digestive and other enzymes.

Considering the achievements of state-of-the-art technologies, no publication questioning the novelty of our procedure has been found in the literature.

Although the complex product with vitamins and minerals manufactured for animals under the Patent number of HU 224 444 contains methyl-methionine sulphonium chloride and kalium iodide, ad 1.: they are only used as components in the food, ad 2.: the advantages of the proper use of these two components are not recognised.

Moreover, the emulsion system of the complex product varies too.
Using our method protected by Patent number P0700175 (applied for by ACHENTY
S.A.: /
UY) we can manufacture a water-soluble product for humans that is capable of restoring the reduced efficacy of food assimilation caused by various reasons.

However, this result is achieved using an emulsion system including all the necessary vitamins, amino acids, minerals and micro elements known to be fundamental, that is completely djerent from our patented procedure presented hereby.

In order for us to achieve our goals, and above all, we need to know the reasons that cause reduced assimilation of food, which eventually can be partially or fully stopped, in terminal phase.

Science undoubtedly has already proved that reduced or insufficient assimilation of food and destroyed assimilation dermises are to blame on the so-called free radicals' that are generated both by metabolites, toxins of viruses, bacteria and fungi, and by harmful environmental emissions causing, amongst others, pollen-, and dust allergies along with radiation-, and chemotherapy treatments, surgeries, UV-, X-ray and radioactive rays.

Similarly, unhealthy nutrition habits or dietary rules, N02-N03 content of food along with medicines, antibiotics causing harm to the wall of intestines and destroying the natural flora of intestines will also multiply the number of free radicals.

For the implementation of the innovation, it undoubtedly was of decisive importance for us to recognise that, first of all, we had to clarify the essence of these 'harmful effects' to be able then to restore the normal functioning of the assimilation dermises of the organism.

The essence of free radicals' was also clarified as being one of all different forms containing one electron-deficit oxygen.

This made it clear for us that, in order for us to achieve the goal of our innovation, we had to develop a product that could get food temporarily into the human organism through - and with the help of- its oxidiser-reductor system, called 'redox'.

First, we had to construct this so-called 'redox' system, day-by-day, using the above mentioned building components in a way that the quantity and proportion of them match the fundamental requirements of a starving organism.

We must emphasize this fact, since now it is not replenishing special foods, but supplying the organism with basic foods using our product, stating at the same time that, using this specific product manufactured during our research and development work, we are capable of restoring the normal level of food assimilation with the highest possible.
speed and efficacy.
During the research and development phase, we found the following composition to be the best at restoring reduced or nearly terminal food assimilation:

A mixture of daily dosage of 30-150 mg of Methyl-methionine sulphonium chloride, 0.20-3.15 mg of kalium-iodide, 11-56 mg ofparaaminobenzoic acid and 6.5-31.0 mg of carboxyl-uracil, transformed in a proper way into water-soluble phase.

Water-solubility was achieved with the highest success by the innovation for this specific occasion through a mixture of 15-43 mg of dimethyl-sulfoxide and 70-350 mg of poliethoxy castor oil.

The direct and indirect anti-oxidant effects ofparaaminobenzoic acid along with methyl-methionine sulphonium chloride are well known and so is the anti-microbial effect of paraaminobenzoic acid.

It is known that the carboxyl-uracil remarkably improves the assimilation of minerals, primarily that of magnesium from intestines.

According to the latest research, but mainly theoratical considerations, this product plays an active role in reparing defficiencies of DNA as well.

The dimethyl-sulfoxide is famous for its successful penetration carrying various organic molecules through the dermis, and since it is generated during intermediate-metabolism, its utilization is obvious.

However, it took us by surprise, as it was unexpected, that it was only the dimethyl-sulfoxide that was able to mix carboxyl-uracil with the emulsion system of our innovation.

Adding iodine to the product manufactured during the implemenation phase seems surprising and question was raised as to how such a strong oxidising substance can be mixed with a system that is basically anti-oxidant.

However, on the other hand, iodine is very important for the organism that considerably improves metabolism, which is especially necessary in our case.
In the course of manufacturing the patented product we have come to a surprising result of unexpected when mixing the non-organic iodine, that is kalium iodide, used for this product, with methyl-methionine sulphonium chloride in a separate procedure, during the manufacturing process.

This unexpected surprising result, the new complex iodide, under certain circumstances - that are determined by the actual 'redox-potential' or electro-motor power of various compounds or compound groups existing in the environment of this new complex - is capable of oxidising and reducing, thus it can restore positive or negative fluctuations in the potential of cell walls / cell membranes, caused by various harmful effects, that eventually result in reduced or fully terminated assimilation offoods.

This phenomenon is similar but not identical to the so-called 'dissipative' systems, known to colloid chemists and physio-chemists, such as the mixture of cerium-sulphate, kalium-bromate, malonic acid and sulphur acid, in which the oxidisation status of the mixture changes in time and space within different time windows.

The discovery of this phenomenon is of paramount importance because any kind of positive or negative of change in the 'redox potential ' of given cell-organelles within the cells of living organisms spells out the beginning of harmful effects including all sorts of diseases and processes of ageing as well.

These changes will also bring about fatal deterioration, and, eventually, a complete loss of efficacy of assimilation through the alimentary canal.

This is what makes it clear how crucial it is that, through the development of our innovative product, we can provide a system that contains anti-oxidants the functioning of which will be secured by a 'redox-molecule' that stabilises the system in a complex formula as detailed above.

This stabilising effect can be detected 'in vitro' as well.

The paramount importance of the 'redox-status' in the cells of living organism is justified by the discovery that won Mr. Otto Warburg the Nobel prize for proving the anaerob - that is reduction - processes that can be detected in cells infected with cancer.

In the course of the manufacturing the product we created a molecule, including methyl-Imethionine iodide with paraaminobenzoic acid and carboxyl-uracil, that becomes water-soluble by adding poliethoxy castor oil and dimethyl-sulfoxide, that brings us to a product that is capable of restoring reduced or terminated assimilation of foods, on its own.

The manufacturing process of our innovative product consists of four steps:

= The production process of the emulsion system to make the fat-soluble ingredients water-soluble - mixing the dilution - during which we take 6.5-31 mg of carboxyl-uracil with 15-43 mg of dimethyl-sulfoxide and mix them with 0-350 mg of Chremophor EL (BASF) heated to a temperature of 65 degrees Centigrade.
Following the 7-minute mixing, the material that has cooled out is homogenous and ready for packing.
= The production process of 'redox-complex' using methyl-methionine sulphonium chloride and kalium-iodide, - mixing the powder -, during which 30-105 mg of methyl-methionine sulphonium chloride is slowly and thoroughly mixed with 0.20-3.15mg of kalium-iodide for 15 minutes.
= Mixing the 'redox-complex , that was produced first, with 11-56 mg of paraaminobenzoic acid,- mixing the powder -, = Packaging the liquid and powder separately into capsules, but our innovative product makes it possible to have the complex in water-soluble, single-phase format.
The versatility of our innovative product also makes it possible for us - in certain cases, when, for example, feeding through infusion-tube is temporarily necessary - to add to the water-soluble format the daily dosages of vitamins, crucial amino acids, unsaturated fatty acids, macro-, and micro elements, such as:
110-180 mg of calcium-lactate, 75-110 mg of vitamin C, 60-100 mg of glutamic acid, 30-45 mg L-asparagic acid, 28-35 mg of L-arginine, 2 7-33 mg of L-Ornihtine, 15-30 mg of L-Cysteine, 3.6-21.5 mg of L-Carnitine, 35-50 mg of vitamin B], 38-45 mg of vitamin B2, 28-60 mg'of vitamin B6, 38-80 mg of Niacin amid, 15-40 mg of Ca d-pantothenate, 13-45 mg of m-Inositol, 5-20 mg of Folic acid, 6-18 mg of Rutin, 0.15-0.40 mg ofd-Biotin, 0.15-0.24 mg of Natrium selenite, 0.21-0.65 mg of Natrium molybdate, 21-62 mg of FeII-lactate, 0.03-0.1 mg of Cobalt-chloride, 25.4-42.0 mg of Zinc chloride, 10-30 mg of Mangane chloride, 20-80 mg of Omega3 oil, 11-20 mg of vitamin E acetate, 4-21.2 mg of l3 karotin, 70-210 mg of soy-lecithin, 900-3600 IU of vitamin A palmitate and 150-240 IU of vitamin D3.

Another advantage of our innovation, in this case, is that there is no specific order for mixing / deluting the above mentioned ingredients.
Through the following, but not exclusive, exhibits, we'd like to introduce our innovation, bearing in mind that they have no limiting effect on the scope ofprotection of the Patent:

Exhibit 1.

For this purpose, we manufactured 1,000 daily dosages of our innovative product (which daily dosage we found sufficient for a 70 kg Chron patient to restore his digestive system which is partly or fully unable to assimilate food) according to the following method:

We mixed 20 gr of carboxyl-uracil and 18 gr of dimethyl-sulfoxide with 210 gr of ChremophorR EL for 7 minutes and stirred steadily in a mixing bowl.

We mixed 102 gr of methyl-methionine sulphonium chloride and 0.30 gr of kalium iodide by stirring for 15 minutes in a laboratory homogeniser, then homogenised this substance once again with an additional 15 gr ofparaaminobenzoic acid.
- We halved both the liquid and the powder, - We packed one of the half quantities, that is 500 dosages, one-by-one, into capsules for voluntary Chron-patients, - We deluted the other half of the quantities with water and mixed in order for us to assess the reaction of the substance during delution with water, should it be needed, Both the emulsion-system and the powdered fraction of the product we have manufactured, following the delution with water separately or in one, is free from sediment, even in case of very thin delution.

Exhibit 2.

Some of the Chron patients were given dosages of our innovative product in capsules your men and three women; one of the men had had 6 cm of his small intestine removed by surgery.
All patients were prescribed to take one liquid and one powder capsule every day.
After 5 days, all the seven patients reported improved appetite, after 2 weeks all of them have put on weights of 1.5-2.3 kg.
Interestingly, the patient that underwent surgery showed the largest rate of growth in weight.
This exhibit proves that the product, manufactured in accordance with the innovaton, itself is capable of restoring terminated or reduced assimilation of food for humans.

5..

Claims (5)

1., The complex product with advanced efficacy in assimilation for humans according to any of claims, that the product contains methyl-methionine sulphonium iodide carboxyl-uracil, paraaminobenzoic acid, dimethyl-sulfoxide and poliethoxy castor oil.

2., The complex product with advanced efficacy in assimilation for humans according to any of claims, that the methyl-methionine sulphonium iodide is made out of kalium-iodide and methyl-methionin sulphonium chloride, in a separate procedure.

3., The complex product with advanced efficacy in assimilation for humans according to any of claims, that, the product, in accordance with Point 2. of claims, is made out of 30-105 weight unit of methyl-methionine sulphonium chloride, 0.20-3.15 weight unit of kalium-iodide, 11-56 weight unit of paraaminobenzoic acid, 5.5-31 weight unit of carboxyl-uracil, 15-43 weight unit of dimethyl-sulfoxide and 70-350 weight unit of poliethoxy castor oil, or the multiple of these weight units.

4., The complex product with advanced efficacy in assimilation for humans according to any of claims, that, the product in accordance with Point 1., of claims, is used for the manufacturing of the product that restores to normal the reduced or terminated capability of assimilation of foods in intestines.

5., The complex product with advanced efficacy in assimilation for humans according to any of claims, that the product, in accordance with Point 1., of claims, in certain cases, can be mixed with:

110-180 mg of calcium-lactate, 75-110 mg of vitamin C, 60-100 mg of glutamic acid, 30-45 mg L-asparagic acid, 28-35 mg of L-arginine, 27-33 mg of L-Ornitin, 15-30 mg L-Cysteine, 3.6-21.5 mg of L-Carnitine, 35-50 mg of vitamin B1, 38-45 mg of vitamin B2, 28-60 mg of vitamin B6, 38-80 mg of Niacin amid, 15-40 mg of Ca d-pantothenate, 13-45 mg of m-Inositol, 5-20 mg of Folic acid, 6-18 mg of Rutin, 0.15-0 40 mg of d-Biotin, 0.15-0.24 mg of Natrium selenite, 0.21-0 65 mg of Natrium molybdate, 21-62 mg of FeII-lactate, 0. 03-0.1 mg of Cobalt-chloride, 25.4-42.0 mg of Zinc chloride, 10-30 mg of Mangane chloride, 20-80 mg of Omega3 oil, 11-20 mg of vitamin E acetate, 4-21.2 mg of .beta. karotin, 70-210 mg of soy-lecithin, 900-3600 IU of vitamin A palmitate and 150-240 IU of vitamin D3.