Nothing Special   »   [go: up one dir, main page]

BRPI1011725A2 - método e sistema para direcionar uma resposta biológica localizada em um implante - Google Patents

método e sistema para direcionar uma resposta biológica localizada em um implante

Info

Publication number
BRPI1011725A2
BRPI1011725A2 BRPI1011725A BRPI1011725A BRPI1011725A2 BR PI1011725 A2 BRPI1011725 A2 BR PI1011725A2 BR PI1011725 A BRPI1011725 A BR PI1011725A BR PI1011725 A BRPI1011725 A BR PI1011725A BR PI1011725 A2 BRPI1011725 A2 BR PI1011725A2
Authority
BR
Brazil
Prior art keywords
implant
directing
biological response
localized biological
localized
Prior art date
Application number
BRPI1011725A
Other languages
English (en)
Inventor
Wisniewski Natalie
A Mcmillan William
Original Assignee
Profusa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Profusa Inc filed Critical Profusa Inc
Publication of BRPI1011725A2 publication Critical patent/BRPI1011725A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14503Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00Devices for applying media, e.g. remedies, on the human body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/50General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/587Lighting arrangements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/005Parameter used as control input for the apparatus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/20Blood composition characteristics
    • A61M2230/201Glucose concentration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0626Monitoring, verifying, controlling systems and methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0635Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645Applicators worn by the patient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/065Light sources therefor
    • A61N2005/0651Diodes
    • A61N2005/0652Arrays of diodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0661Radiation therapy using light characterised by the wavelength of light used ultraviolet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/067Radiation therapy using light using laser light

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Electrotherapy Devices (AREA)
BRPI1011725A 2009-06-01 2010-05-28 método e sistema para direcionar uma resposta biológica localizada em um implante BRPI1011725A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18299509P 2009-06-01 2009-06-01
US12/789,048 US9517023B2 (en) 2009-06-01 2010-05-27 Method and system for directing a localized biological response to an implant
PCT/US2010/036698 WO2010141377A2 (en) 2009-06-01 2010-05-28 Method and system for directing a localized biological response to an implant

Publications (1)

Publication Number Publication Date
BRPI1011725A2 true BRPI1011725A2 (pt) 2017-03-21

Family

ID=43220477

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1011725A BRPI1011725A2 (pt) 2009-06-01 2010-05-28 método e sistema para direcionar uma resposta biológica localizada em um implante

Country Status (8)

Country Link
US (2) US9517023B2 (pt)
EP (1) EP2437846B1 (pt)
JP (2) JP2012528686A (pt)
CN (1) CN102458560B (pt)
AU (1) AU2010256930B2 (pt)
BR (1) BRPI1011725A2 (pt)
CA (1) CA2763687C (pt)
WO (1) WO2010141377A2 (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9517023B2 (en) 2009-06-01 2016-12-13 Profusa, Inc. Method and system for directing a localized biological response to an implant
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
US10852069B2 (en) 2010-05-04 2020-12-01 Fractal Heatsink Technologies, LLC System and method for maintaining efficiency of a fractal heat sink
US10010272B2 (en) 2010-05-27 2018-07-03 Profusa, Inc. Tissue-integrating electronic apparatus
KR101690535B1 (ko) 2010-10-06 2017-01-09 프로퓨사 인코퍼레이티드 조직-일체화 센서
JP2015515886A (ja) 2012-05-01 2015-06-04 ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 経皮挿入するための先端装填型マイクロニードルアレイ
EP2967454B1 (en) * 2013-03-14 2020-04-22 Profusa, Inc. Method and device for correcting optical signals
WO2014160258A1 (en) 2013-03-14 2014-10-02 Profusa, Inc. Oxygen sensors
AU2014232969A1 (en) * 2013-03-15 2015-10-15 Prometheon Pharma, Llc Devices, systems, and methods for transdermal delivery of compounds
CA2913474C (en) 2013-06-06 2023-04-18 William A. Mcmillan Apparatus and methods for detecting optical signals from implanted sensors
EP3180065A4 (en) 2014-07-24 2018-04-11 Thomas Jefferson University Long-term implantable monitoring system & methods of use
WO2016149673A1 (en) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bioactive components conjugated to substrates of microneedle arrays
BR112017028113A2 (pt) * 2015-06-25 2018-08-28 Profusa Inc leitora transcutânea para uso com sensores de analito transplantáveis
US9838576B2 (en) 2015-08-31 2017-12-05 Panasonic Corporation Endoscope
US11684763B2 (en) 2015-10-16 2023-06-27 University of Pittsburgh—of the Commonwealth System of Higher Education Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices
US11744889B2 (en) 2016-01-05 2023-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
WO2018017196A1 (en) * 2016-07-18 2018-01-25 Siemens Healthcare Diagnostics Inc. Biofouling prevention of wearable sensors and methods of use and calibration related thereto
CN106618591A (zh) * 2016-11-03 2017-05-10 深圳市元征软件开发有限公司 一种检测血糖的方法及植入设备
CN115505280A (zh) 2016-12-21 2022-12-23 普罗菲尤萨股份有限公司 可聚合的近红外染料
US11331018B2 (en) 2016-12-22 2022-05-17 Profusa, Inc. System and single-channel biosensor for and method of determining analyte value
WO2018169975A1 (en) * 2017-03-13 2018-09-20 Profusa, Inc. Inserter and method of inserting an implant under the skin
US10413658B2 (en) 2017-03-31 2019-09-17 Capillary Biomedical, Inc. Helical insertion infusion device
KR20200094724A (ko) 2017-06-29 2020-08-07 프로퓨사 인코퍼레이티드 다중-분석물 감지 조직-통합 센서
WO2019194875A2 (en) 2017-12-28 2019-10-10 Profusa, Inc. Oxidase-based sensors and methods of using
WO2019157018A1 (en) * 2018-02-06 2019-08-15 Mencanin Steve Apparatus for and method of treating viral infections
EP3545897A1 (en) * 2018-03-29 2019-10-02 Koninklijke Philips N.V. An implantable device
WO2019231505A1 (en) * 2018-06-02 2019-12-05 Mencanin Steve Apparatus for and method of treating viral infections
US12214150B2 (en) 2019-05-16 2025-02-04 University of Pittsburgh—of the Commonwealth System of Higher Education Microneedle arrays with undercut features for cutaneous and non-cutaneous drug delivery
WO2021242805A1 (en) * 2020-05-29 2021-12-02 Know Bio, Llc Devices and related methods for light-based modulation of foreign body responses in living tissue
EP4204066A4 (en) 2020-08-28 2024-11-13 Tandem Diabetes Care, Inc. INSULIN INFUSION SET
CN113289237A (zh) * 2021-05-19 2021-08-24 中山大学 基于离子导入驱动的触控微针阵列诊疗一体化可穿戴设备

Family Cites Families (148)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703756A (en) 1986-05-06 1987-11-03 The Regents Of The University Of California Complete glucose monitoring system with an implantable, telemetered sensor module
US5342789A (en) 1989-12-14 1994-08-30 Sensor Technologies, Inc. Method and device for detecting and quantifying glucose in body fluids
US6040194A (en) 1989-12-14 2000-03-21 Sensor Technologies, Inc. Methods and device for detecting and quantifying substances in body fluids
US5284140A (en) 1992-02-11 1994-02-08 Eli Lilly And Company Acrylic copolymer membranes for biosensors
US5882494A (en) 1995-03-27 1999-03-16 Minimed, Inc. Polyurethane/polyurea compositions containing silicone for biosensor membranes
WO1997019188A1 (en) 1995-11-22 1997-05-29 Minimed, Inc. Detection of biological molecules using chemical amplification and optical sensors
US5711861A (en) 1995-11-22 1998-01-27 Ward; W. Kenneth Device for monitoring changes in analyte concentration
US6766183B2 (en) 1995-11-22 2004-07-20 Medtronic Minimed, Inc. Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers
US6002954A (en) 1995-11-22 1999-12-14 The Regents Of The University Of California Detection of biological molecules using boronate-based chemical amplification and optical sensors
AUPN814496A0 (en) 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
GB9616896D0 (en) 1996-08-12 1996-09-25 British Tech Group Pharmaceutical compositions
WO1998022820A1 (en) * 1996-11-21 1998-05-28 Lawrence Livermore National Laboratory Detection of biological molecules using boronate-based chemical amplification and optical sensors
US6043437A (en) 1996-12-20 2000-03-28 Alfred E. Mann Foundation Alumina insulation for coating implantable components and other microminiature devices
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US7192450B2 (en) 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US6741877B1 (en) 1997-03-04 2004-05-25 Dexcom, Inc. Device and method for determining analyte levels
US5895658A (en) 1997-09-17 1999-04-20 Fossel; Eric T. Topical delivery of L-arginine to cause tissue warming
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
GB9814506D0 (en) 1998-07-03 1998-09-02 Stanley Christopher J Optical sensor for insitu measurement of analytes
EP1094745B1 (en) 1998-07-04 2010-05-19 Whitland Research Limited Non-invasive measurement of blood analytes
US6013122A (en) 1998-08-18 2000-01-11 Option Technologies, Inc. Tattoo inks
JP4898991B2 (ja) 1998-08-20 2012-03-21 クック メディカル テクノロジーズ エルエルシー 被覆付植込式医療装置
DK1108207T3 (da) 1998-08-26 2008-08-18 Sensors For Med & Science Inc Optisk baserede sensorindretning
US6602678B2 (en) 1998-09-04 2003-08-05 Powderject Research Limited Non- or minimally invasive monitoring methods
US20030099682A1 (en) 1998-11-20 2003-05-29 Francis Moussy Apparatus and method for control of tissue/implant interactions
US6366794B1 (en) 1998-11-20 2002-04-02 The University Of Connecticut Generic integrated implantable potentiostat telemetry unit for electrochemical sensors
US6783937B1 (en) 1999-02-25 2004-08-31 Pall Corporation Negatively charged membrane
US8346363B2 (en) 1999-03-05 2013-01-01 Metacure Limited Blood glucose level control
US6475750B1 (en) 1999-05-11 2002-11-05 M-Biotech, Inc. Glucose biosensor
US6682938B1 (en) * 1999-09-15 2004-01-27 The Regents Of The University Of California Glucose sensing molecules having selected fluorescent properties
US20050119737A1 (en) 2000-01-12 2005-06-02 Bene Eric A. Ocular implant and methods for making and using same
US20020043651A1 (en) 2000-04-04 2002-04-18 Darrow Christopher B. Fluorescent lifetime assays for non-invasive quantification of analytes such as glucose
US6565960B2 (en) 2000-06-01 2003-05-20 Shriners Hospital Of Children Polymer composite compositions
AU2001279127A1 (en) * 2000-08-01 2002-02-13 University Of Washington Methods and devices to modulate the wound response
AU7814501A (en) 2000-08-04 2002-02-18 Sensors For Med & Science Inc Detection of analytes in aqueous environments
GB0025147D0 (en) 2000-10-13 2000-11-29 Torsana Diabetes Diagnostics A Optical sensor for in situ measurement of analytes
US6642015B2 (en) 2000-12-29 2003-11-04 Minimed Inc. Hydrophilic polymeric material for coating biosensors
US8069254B2 (en) 2001-02-28 2011-11-29 Sharp Laboratories Of America, Inc. Communication period management in a communication system
US6694158B2 (en) 2001-04-11 2004-02-17 Motorola, Inc. System using a portable detection device for detection of an analyte through body tissue
EP1385423B1 (en) 2001-04-27 2007-11-21 EyeSense AG Kit for measuring blood glucose concentrations
WO2002087696A1 (en) * 2001-04-30 2002-11-07 Medtronic,Inc. Transcutaneous monitor and method of use, using therapeutic output from an implanted medical device
FI20010898A0 (fi) 2001-04-30 2001-04-30 Ylae Herttuala Seppo Ekstrasellulaarinen superoksididismutaasi (EC-SOD) geeniterapia restenoosoin ehkäisemiseksi
US6844028B2 (en) 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
GB0116853D0 (en) 2001-07-10 2001-09-05 Torsana Diabetes Diagnostics A Optical sensor containing particles for in SITU measurement of analytes
US6702857B2 (en) 2001-07-27 2004-03-09 Dexcom, Inc. Membrane for use with implantable devices
EP1519678A2 (en) 2001-10-02 2005-04-06 Alfred E. Mann Institute for Biomedical Engineering at the University of Southern California Internal biochemical sensing device
US7202947B2 (en) 2001-12-19 2007-04-10 Wisconsin Alumni Research Foundation Depth-resolved fluorescence instrument with angled excitation
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
GB0204640D0 (en) 2002-02-27 2002-04-10 Torsana Diabetes Diagnostics A Injection apparatus
US7813780B2 (en) 2005-12-13 2010-10-12 Medtronic Minimed, Inc. Biosensors and methods for making and using them
US7153265B2 (en) 2002-04-22 2006-12-26 Medtronic Minimed, Inc. Anti-inflammatory biosensor for reduced biofouling and enhanced sensor performance
US20030208166A1 (en) 2002-05-06 2003-11-06 Schwartz Anthony H. Implantable device with free-flowing exit and uses thereof
CN1655738A (zh) 2002-05-20 2005-08-17 奥勃斯医学技术股份有限公司 可植入的药物洗脱医疗装置
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
US7162289B2 (en) 2002-09-27 2007-01-09 Medtronic Minimed, Inc. Method and apparatus for enhancing the integrity of an implantable sensor device
US20040106951A1 (en) 2002-11-22 2004-06-03 Edman Carl Frederick Use of electric fields to minimize rejection of implanted devices and materials
US20040143221A1 (en) 2002-12-27 2004-07-22 Shadduck John H. Biomedical implant for sustained agent release
WO2004061420A2 (en) 2002-12-31 2004-07-22 Therasense, Inc. Continuous glucose monitoring system and methods of use
US7406345B2 (en) 2003-02-14 2008-07-29 Eyesense Ag Apparatus for measuring an analyte concentration from an ocular fluid
WO2004076500A1 (en) 2003-02-28 2004-09-10 Novartis Ag Copolymers comprising biomolecules
US6965791B1 (en) 2003-03-26 2005-11-15 Sorenson Medical, Inc. Implantable biosensor system, apparatus and method
US6828572B2 (en) 2003-04-01 2004-12-07 Axcelis Technologies, Inc. Ion beam incident angle detector for ion implant systems
US7134999B2 (en) 2003-04-04 2006-11-14 Dexcom, Inc. Optimized sensor geometry for an implantable glucose sensor
US20070010702A1 (en) 2003-04-08 2007-01-11 Xingwu Wang Medical device with low magnetic susceptibility
US7186789B2 (en) 2003-06-11 2007-03-06 Advanced Cardiovascular Systems, Inc. Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings
WO2005015184A1 (en) 2003-07-30 2005-02-17 Novartis Ag Reflection hologram sensor in contact lens
US20050027175A1 (en) 2003-07-31 2005-02-03 Zhongping Yang Implantable biosensor
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US8131333B2 (en) 2003-08-07 2012-03-06 Eyesense Ag Ophthalmic sensor
US9687368B2 (en) 2003-08-13 2017-06-27 Medtronic Vascular, Inc. Biocompatible controlled release coatings for medical devices and related methods
WO2005032418A2 (en) 2003-10-01 2005-04-14 University Of Washington Novel porous biomaterials
WO2005041767A2 (en) * 2003-11-03 2005-05-12 Microchips, Inc. Medical device for sensing glucose
WO2005051232A2 (en) * 2003-11-20 2005-06-09 Angiotech International Ag Soft tissue implants and anti-scarring agents
US7146203B2 (en) 2003-12-18 2006-12-05 Elliot Botvinick Implantable biosensor and methods of use thereof
US20060002969A1 (en) 2004-01-27 2006-01-05 University Of Washington Methods for reducing the foreign body reaction
US7450980B2 (en) 2004-03-31 2008-11-11 Terumo Kabushiki Kaisha Intracorporeal substance measuring assembly
US20050245799A1 (en) 2004-05-03 2005-11-03 Dexcom, Inc. Implantable analyte sensor
US8849416B2 (en) 2004-05-04 2014-09-30 University Of Rochester Implantable bio-electro-physiologic interface matrix
GB0411162D0 (en) 2004-05-19 2004-06-23 Precisense As Optical sensor for in vivo detection of analyte
US8690865B2 (en) * 2004-05-28 2014-04-08 Georgia Tech Research Corporation Methods and devices for thermal treatment
JP4856633B2 (ja) 2004-06-02 2012-01-18 カール フレデリック エドゥマン 植え込まれたデバイス及び物質への拒絶反応を最小化するための電界を印加する装置
ATE447355T1 (de) 2004-06-14 2009-11-15 Eyesense Ag Kombiniertes gerät zum messen von blutzucker aus augenflüssigkeit
EP1782062A4 (en) 2004-08-24 2010-09-08 Univ South Florida EPOXY-IMPROVED POLYMER MEMBRANE FOR INCREASING THE DURABILITY OF BIOSENSORS
US7166680B2 (en) 2004-10-06 2007-01-23 Advanced Cardiovascular Systems, Inc. Blends of poly(ester amide) polymers
US7248907B2 (en) 2004-10-23 2007-07-24 Hogan Josh N Correlation of concurrent non-invasively acquired signals
GB0426822D0 (en) 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
JP2006296511A (ja) * 2005-04-15 2006-11-02 Transcutaneous Technologies Inc 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ
WO2006121522A2 (en) * 2005-05-10 2006-11-16 Angiotech International Ag Implantable sensors and pumps, anti-scarring agents, and therapeutic compositions
US20060269591A1 (en) * 2005-05-27 2006-11-30 William Hart Discrete patch for viral lesions
US7704704B2 (en) * 2005-09-28 2010-04-27 The Texas A&M University System Implantable system for glucose monitoring using fluorescence quenching
US8515518B2 (en) 2005-12-28 2013-08-20 Abbott Diabetes Care Inc. Analyte monitoring
US8160670B2 (en) * 2005-12-28 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring: stabilizer for subcutaneous glucose sensor with incorporated antiglycolytic agent
US8114269B2 (en) 2005-12-30 2012-02-14 Medtronic Minimed, Inc. System and method for determining the point of hydration and proper time to apply potential to a glucose sensor
US20100202966A1 (en) 2006-03-28 2010-08-12 Yossi Gross Implantable Sensor
US7809441B2 (en) 2006-05-17 2010-10-05 Cardiac Pacemakers, Inc. Implantable medical device with chemical sensor and related methods
WO2008105791A2 (en) 2006-06-22 2008-09-04 University Of South Florida Collagen scaffolds, medical implants with same and methods of use
DK1882446T3 (da) 2006-07-24 2009-01-12 Eyesense Ag Anordning til måling af en analyt i en öjenvæske
WO2008143651A2 (en) 2006-12-07 2008-11-27 The Ohio State University Research Foundation A system for in vivo biosensing based on the optical response of electronic polymers
US20080139903A1 (en) 2006-12-08 2008-06-12 Isense Corporation Method and apparatus for insertion of a sensor using an introducer
DE102007003341B4 (de) 2007-01-17 2018-01-04 Eyesense Ag Okularsensor und Messsystem zum Nachweis eines Analyten in einer Augenflüssigkeit
WO2008141241A1 (en) 2007-05-10 2008-11-20 Glumetrics, Inc. Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement
DE102007024642A1 (de) 2007-05-24 2008-11-27 Eyesense Ag Hydrogel-Implantat für Sensorik von Metaboliten am Auge
GB0715590D0 (en) 2007-08-09 2007-09-19 Glysure Ltd Sensing apparatus
WO2009067626A1 (en) 2007-11-21 2009-05-28 Glumetrics, Inc. Use of an equilibrium intravascular sensor to achieve tight glycemic control
GB0800278D0 (en) 2008-01-08 2008-02-13 Glysure Ltd Surface functionalisation
GB0803492D0 (en) 2008-02-26 2008-04-02 Glysure Ltd Fibre optic sensor
US8080821B2 (en) 2008-03-18 2011-12-20 The University Of Connecticut Thyristor radiation detector array and applications thereof
WO2009129186A2 (en) 2008-04-17 2009-10-22 Glumetrics, Inc. Sensor for percutaneous intravascular deployment without an indwelling cannula
US8986208B2 (en) 2008-09-30 2015-03-24 Abbott Diabetes Care Inc. Analyte sensor sensitivity attenuation mitigation
EP2174586B1 (de) 2008-10-02 2014-12-10 EyeSense AG Implantierbares Sensorelement
EP2174587B1 (de) 2008-10-02 2011-05-04 EyeSense AG Implantationsvorrichtung für Metabolitsensoren
US20100160749A1 (en) 2008-12-24 2010-06-24 Glusense Ltd. Implantable optical glucose sensing
EP2424426B1 (en) 2009-04-29 2020-01-08 Abbott Diabetes Care, Inc. Method and system for providing data communication in continuous glucose monitoring and management system
WO2010133831A1 (en) 2009-05-18 2010-11-25 Glysure Ltd Glucose sensor calibration
US9517023B2 (en) 2009-06-01 2016-12-13 Profusa, Inc. Method and system for directing a localized biological response to an implant
US20110028806A1 (en) 2009-07-29 2011-02-03 Sean Merritt Reflectance calibration of fluorescence-based glucose measurements
EP2314608A1 (de) 2009-10-26 2011-04-27 EyeSense AG Stabilisierung von Biosensoren für in vivo Anwendungen
US8372423B2 (en) 2009-11-25 2013-02-12 Healionics Corporation Implantable medical devices having microporous surface layers and method for reducing foreign body response to the same
US9151764B2 (en) 2010-02-16 2015-10-06 Lightship Medical Limited Barrier layer for glucose sensor
JP5881120B2 (ja) 2010-02-19 2016-03-09 グリシュア リミテッド 血管内グルコースセンサ
US8579879B2 (en) 2010-02-19 2013-11-12 Medtronic Minimed, Inc. Closed-loop glucose control startup
AU2011217066A1 (en) 2010-02-19 2012-09-06 Lightship Medical Limited Indicator system for fibre optic sensor
WO2011101625A1 (en) 2010-02-19 2011-08-25 Glysure Ltd Subcutaneous glucose sensor
AU2011217069A1 (en) 2010-02-19 2012-09-06 Lightship Medical Limited Fluorescence measurement
KR101837481B1 (ko) 2010-03-17 2018-03-13 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 생체흡수성 기판 상 이식가능한 바이오의료 장치
US10010272B2 (en) 2010-05-27 2018-07-03 Profusa, Inc. Tissue-integrating electronic apparatus
US8543354B2 (en) 2010-06-23 2013-09-24 Medtronic Minimed, Inc. Glucose sensor signal stability analysis
KR101690535B1 (ko) 2010-10-06 2017-01-09 프로퓨사 인코퍼레이티드 조직-일체화 센서
US9131136B2 (en) 2010-12-06 2015-09-08 Apple Inc. Lens arrays for pattern projection and imaging
EP2652510B1 (de) 2010-12-17 2016-06-22 EyeSense AG Verwendung von hydrogelen für biosensoren mit erhöhter sensitivität
CN103328980B (zh) 2010-12-17 2016-01-20 视觉股份公司 具有提高的敏感性的竞争性生物传感器
US20120245445A1 (en) 2011-03-21 2012-09-27 Michael Darryl Black Glucose Monitoring System
US9008744B2 (en) 2011-05-06 2015-04-14 Medtronic Minimed, Inc. Method and apparatus for continuous analyte monitoring
US9037205B2 (en) 2011-06-30 2015-05-19 Glusense, Ltd Implantable optical glucose sensing
EP2744399B1 (en) 2011-08-15 2017-07-12 University of Connecticut Control of biofouling in implantable biosensors
US9642568B2 (en) 2011-09-06 2017-05-09 Medtronic Minimed, Inc. Orthogonally redundant sensor systems and methods
US20130158413A1 (en) 2011-12-15 2013-06-20 Nellcor Puritan Bennett Llc Optical measurement of physiological blood parameters
US8891088B2 (en) 2012-01-20 2014-11-18 The Curators Of The University Of Missouri Total internal reflection photoacoustic spectroscopy
DE102012201892A1 (de) 2012-02-09 2013-08-14 Robert Bosch Gmbh Bestimmung des Blutzuckerspiegels eines Patienten unter Verwendung eines implantierbaren Sensors und eines elektrischen Funktionspflasters
US9693714B2 (en) 2012-02-10 2017-07-04 Senseonics, Incorporated Digital ASIC sensor platform
US8869588B2 (en) 2012-02-21 2014-10-28 Symbol Technologies, Inc. Ultrasonic positioning system with reverberation and flight time compensation
CN104159500B (zh) 2012-03-08 2018-08-07 皇家飞利浦有限公司 用于确定组织的特性的装置
EP2967454B1 (en) 2013-03-14 2020-04-22 Profusa, Inc. Method and device for correcting optical signals
CA2913474C (en) 2013-06-06 2023-04-18 William A. Mcmillan Apparatus and methods for detecting optical signals from implanted sensors
BR112017028113A2 (pt) 2015-06-25 2018-08-28 Profusa Inc leitora transcutânea para uso com sensores de analito transplantáveis

Also Published As

Publication number Publication date
CN102458560A (zh) 2012-05-16
EP2437846A2 (en) 2012-04-11
CN102458560B (zh) 2014-06-25
WO2010141377A2 (en) 2010-12-09
US20100303772A1 (en) 2010-12-02
JP6073959B2 (ja) 2017-02-01
AU2010256930B2 (en) 2015-09-17
JP2012528686A (ja) 2012-11-15
US20170087376A1 (en) 2017-03-30
US10583308B2 (en) 2020-03-10
CA2763687C (en) 2023-05-23
EP2437846B1 (en) 2021-06-23
WO2010141377A3 (en) 2011-04-07
CA2763687A1 (en) 2010-12-09
AU2010256930A1 (en) 2011-12-22
US9517023B2 (en) 2016-12-13
JP2015171550A (ja) 2015-10-01
EP2437846A4 (en) 2015-09-23

Similar Documents

Publication Publication Date Title
BRPI1011725A2 (pt) método e sistema para direcionar uma resposta biológica localizada em um implante
BRPI1012599A2 (pt) sistema e método para a colocação de uma prótese endoluminal em um local cirúrgico
BRPI0911078A2 (pt) sistema e método para a projetar e formar um implante cirúrgico
BRPI0814077A2 (pt) Controlador e sistema e método para medir consumo de energia.
BR112012012231A2 (pt) método e sistema
BRPI0921659A2 (pt) metodo e sistema para formar uma protese dentaria
BRPI1015164A2 (pt) método e sistema para gerar automaticamente conteúdo específico de localização para uma entidade particular, e, método e sistema para fornecer conteúdo específico de localização para uma entidade particular tendo uma pluralidade de localizações físicas
BRPI0912794A2 (pt) sistema e método para controlar uma plantadeira
BR112012010299A2 (pt) método implementado por computador, e, sistema para a realização de um método de caracterização
BR112012002301A2 (pt) método e sistema
BR112012006947A2 (pt) método e sistema para a fabricação de uma peça dental em camadas
BRPI0923566A2 (pt) método e sistema para detecção de uma expressão vocal relevante
BRPI0823032A2 (pt) Método e sistema para gerenciar potência em um sistema de elevador
BRPI1006265A2 (pt) unidade de flutuação, sistema e método para a operação de uma unidade de flutuação
BRPI1010203A2 (pt) sistema e método
BRPI1006434A2 (pt) encosto para um sistema de ressuscitação cardiopulmonar automatizado e sistema de ressuscitação cardiopulmonar automatizado
BRPI0907548A2 (pt) Sistema e método de rastreamento da zona dental para uma escova de dentes
BRPI1006398A2 (pt) método e sistema
BRPI0915864A2 (pt) método e sistema para controle de giroscópio e gnss combinados
BR112013015870A2 (pt) método para o tratamento de biomassa e sistema
BRPI0817450A2 (pt) Sistema e método para determinar a força descendente apropriada para uma unidade de fila de plantar
BRPI1008076A2 (pt) sistema, método e aparelho para implementar implantes dentários
BRPI0909748A2 (pt) sistema e método de simulação
BRPI1006885A2 (pt) sistema de completação utilizável com um poço, e método utilizável com um poço
BRPI0813757A2 (pt) Sistema de implante, e, método

Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: PROFUSA, INC. (US)

B25H Request for change of headquarter rejected

Owner name: PROFUSA, INC. (US)

Free format text: INDEFERIDO O PEDIDO DE ALTERACAO DE SEDE CONTIDO NA PETICAO 20120063760 DE 10/07/2012,POR JA TER SIDO ATENDIDO NA RPI2496 DE 06/11/2018.

B25G Requested change of headquarter approved

Owner name: PROFUSA, INC. (US)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2673 DE 29-03-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.