BRPI0811220A2 - Compostos terapêuticos - Google Patents

Compostos terapêuticos

Info

Publication number: BRPI0811220A2
Authority: BR; Brazil
Prior art keywords: therapeutic compounds; anesthetic; stereoisomer; prodrug; useful
Prior art date: 2007-05-09

Application number

BRPI0811220-7A2A

Other languages

English (en)

Inventor

Thomas E Jenkins

Original Assignee

Pharmacofore Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-05-09

Filing date

2008-05-08

Publication date

2014-10-29

2008-05-08 Application filed by Pharmacofore Inc filed Critical Pharmacofore Inc

2014-10-29 Publication of BRPI0811220A2 publication Critical patent/BRPI0811220A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with no unsaturation outside the aromatic ring
- C07C39/06—Alkylated phenols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/44—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
- C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
- C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
- C07C37/0555—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group being esterified hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/24—Halogenated derivatives
- C07C39/26—Halogenated derivatives monocyclic monohydroxylic containing halogen bound to ring carbon atoms
- C07C39/27—Halogenated derivatives monocyclic monohydroxylic containing halogen bound to ring carbon atoms all halogen atoms being bound to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Epidemiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

BRPI0811220-7A2A 2007-05-09 2008-05-08 Compostos terapêuticos BRPI0811220A2 (pt)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US92832707P	2007-05-09	2007-05-09
US92842907P	2007-05-09	2007-05-09
US92829607P	2007-05-09	2007-05-09
PCT/US2008/063082 WO2008141097A2 (en)	2007-05-09	2008-05-08	Stereoisomers propofol therapeutic compounds

Publications (1)

Publication Number	Publication Date
BRPI0811220A2 true BRPI0811220A2 (pt)	2014-10-29

Family

ID=39798084

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0811220-7A2A BRPI0811220A2 (pt)	2007-05-09	2008-05-08	Compostos terapêuticos

Country Status (23)

Country	Link
US (4)	US8071818B2 (pt)
EP (4)	EP2292577A1 (pt)
JP (1)	JP5651009B2 (pt)
KR (1)	KR20100017436A (pt)
CN (1)	CN101715437B (pt)
AT (1)	ATE487685T1 (pt)
AU (1)	AU2008251482C1 (pt)
BR (1)	BRPI0811220A2 (pt)
CA (1)	CA2685570A1 (pt)
DE (1)	DE602008003431D1 (pt)
DK (2)	DK2301908T3 (pt)
ES (1)	ES2501592T3 (pt)
HK (2)	HK1138829A1 (pt)
HR (1)	HRP20140896T1 (pt)
IL (1)	IL201795A0 (pt)
MX (1)	MX2009012124A (pt)
NZ (1)	NZ580752A (pt)
PL (2)	PL2301908T3 (pt)
PT (1)	PT2146946E (pt)
RU (1)	RU2470908C2 (pt)
SI (1)	SI2301908T1 (pt)
WO (1)	WO2008141097A2 (pt)
ZA (1)	ZA201007603B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0811220A2 (pt)	2007-05-09	2014-10-29	Pharmacofore Inc	Compostos terapêuticos
WO2012017950A1 (ja) *	2010-08-03	2012-02-09	学校法人久留米大学	実験用小動物の脳波測定用電極装置及び脳波測定方法
CN102731265B (zh) *	2012-06-12	2014-12-10	四川百利药业有限责任公司	一种高纯度丙泊酚的制备方法
WO2017205632A1 (en) *	2016-05-27	2017-11-30	The Johns Hopkins University	Buccal, sublingual and intranasal delivery of fospropofol
RU2635532C1 (ru) *	2016-09-06	2017-11-13	Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации	Способ профилактики ажитационного синдрома у детей с онкологической патологией
CN115708819A (zh) *	2022-11-24	2023-02-24	中国科学院深圳先进技术研究院	丙泊酚的抗焦虑制药用途及抗焦虑药物制剂

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US237213A (en)		1881-02-01		William j
US2747982A (en) *	1955-05-11	1956-05-29	Dow Chemical Co	Method and composition for the control of the growth of vegetation
GB1472793A (en)	1974-03-28	1977-05-04	Ici Ltd	Pharmaceutical compositions
US4798846A (en)	1974-03-28	1989-01-17	Imperial Chemical Industries Plc	Pharmaceutical compositions
SU1525139A1 (ru) *	1987-11-10	1989-11-30	Куйбышевский политехнический институт им.В.В.Куйбышева	Способ получени о-втор-бутилфенола
ES2087019B1 (es) *	1994-02-08	1997-03-16	Bobel246 S L	Uso de derivados de fenoles 2,4-disubstituidos como inhibidores de la 5-lipoxigenasa.
GB9405593D0 (en)	1994-03-22	1994-05-11	Zeneca Ltd	Pharmaceutical compositions
US5731355A (en) *	1994-03-22	1998-03-24	Zeneca Limited	Pharmaceutical compositions of propofol and edetate
US6254853B1 (en)	1998-05-08	2001-07-03	Vyrex Corporation	Water soluble pro-drugs of propofol
US6204257B1 (en)	1998-08-07	2001-03-20	Universtiy Of Kansas	Water soluble prodrugs of hindered alcohols
US6140374A (en) *	1998-10-23	2000-10-31	Abbott Laboratories	Propofol composition
EP1161226B1 (en)	1999-02-18	2004-05-26	SuperGen, Inc.	Phosphocholine linked prodrug derivatives
US6716452B1 (en)	2000-08-22	2004-04-06	New River Pharmaceuticals Inc.	Active agent delivery systems and methods for protecting and administering active agents
US6362234B1 (en)	2000-08-15	2002-03-26	Vyrex Corporation	Water-soluble prodrugs of propofol for treatment of migrane
US20020099013A1 (en)	2000-11-14	2002-07-25	Thomas Piccariello	Active agent delivery systems and methods for protecting and administering active agents
EP1358200A4 (en)	2000-10-06	2005-07-20	Xenoport Inc	COMPOUNDS DERIVED FROM GALLENIC ACID TO IMPROVE THE ORAL ABSORPTION AND SYSTEMIC BIOVERABILITY OF MEDICAMENTS
JP4334229B2 (ja) *	2001-03-20	2009-09-30	サイデックス・ファーマシューティカルズ・インコーポレイテッド	プロポフォール及びスルホアルキルエーテルシクロデキストリン含有製剤
PL205271B1 (pl)	2001-12-28	2010-03-31	Mgi Gp	Kompozycja farmaceutyczna rozpuszczalnego w wodzie proleku propofolu
EP1485082A4 (en)	2002-02-19	2009-12-30	Xenoport Inc	PROCESS FOR THE SYNTHESIS OF PROMEDICAMENTS FROM 1-ACYL-ALKYL DERIVATIVES AND CORRESPONDING COMPOSITIONS
CA2480881C (en)	2002-04-08	2012-09-11	Guilford Pharmaceuticals, Inc.	Pharmaceutical compositions containing water-soluble prodrugs of propofol and methods of administering same
DE20215415U1 (de)	2002-10-08	2004-02-26	Biotechnologie Gesellschaft Mittelhessen Mbh	Wasserlösliche Medikamentenvorstufen von Propofol
US7538092B2 (en)	2002-10-08	2009-05-26	Fresenius Kabi Deutschland Gmbh	Pharmaceutically active oligosaccharide conjugates
ZA200504940B (en)	2003-01-28	2006-09-27	Xenoport Inc	Amino acid derived prodrugs of propofol, compositions and uses thereof
AU2003901815A0 (en)	2003-04-15	2003-05-01	Vital Health Sciences Pty Ltd	Phosphate derivatives
US7230003B2 (en)	2003-09-09	2007-06-12	Xenoport, Inc.	Aromatic prodrugs of propofol, compositions and uses thereof
US20070043121A1 (en) *	2003-09-29	2007-02-22	Brown Milton L	Discovery of novel soluble crystalline anesthetics
WO2006017351A1 (en)	2004-07-12	2006-02-16	Xenoport, Inc.	Prodrugs of propofol, compositions and uses thereof
US20080214508A1 (en)	2004-09-17	2008-09-04	Mgi Gp, Inc.	Methods of Administering Water-Soluble Prodrugs of Propofol
ES2340189T3 (es)	2004-12-23	2010-05-31	Xenoport, Inc.	Profarmacos de propofol derivados del aminoacido serina, composiciones, usos y formas cristalinas de los mismos.
DE102005033496A1 (de) *	2005-07-19	2007-01-25	Bayer Healthcare Ag	Desinfektionsmittel
AU2006328198B2 (en) *	2005-12-19	2013-07-18	Medizinische Hochschule Hannover	Substituted phenol derivatives as analgesics
US7535698B2 (en)	2006-03-07	2009-05-19	Panasonic Corporation	Case, portable information equipment using the same and manufacturing method of the case
US7731356B1 (en) *	2006-07-24	2010-06-08	Daniel Ayers Gilbert	Hanging eyeglasses
BRPI0811220A2 (pt)	2007-05-09	2014-10-29	Pharmacofore Inc	Compostos terapêuticos
BRPI0811284A2 (pt)	2007-05-09	2015-01-20	Pharmacofore Inc	Compostos terapêuticos

2008
- 2008-05-08 BR BRPI0811220-7A2A patent/BRPI0811220A2/pt not_active IP Right Cessation
- 2008-05-08 ES ES10014318.9T patent/ES2501592T3/es active Active
- 2008-05-08 AU AU2008251482A patent/AU2008251482C1/en not_active Ceased
- 2008-05-08 EP EP10009233A patent/EP2292577A1/en not_active Withdrawn
- 2008-05-08 US US12/596,800 patent/US8071818B2/en not_active Expired - Fee Related
- 2008-05-08 KR KR1020097024780A patent/KR20100017436A/ko not_active Application Discontinuation
- 2008-05-08 DK DK10014318.9T patent/DK2301908T3/da active
- 2008-05-08 CA CA002685570A patent/CA2685570A1/en not_active Abandoned
- 2008-05-08 EP EP10014318.9A patent/EP2301908B8/en active Active
- 2008-05-08 NZ NZ580752A patent/NZ580752A/en not_active IP Right Cessation
- 2008-05-08 WO PCT/US2008/063082 patent/WO2008141097A2/en active Application Filing
- 2008-05-08 JP JP2010507665A patent/JP5651009B2/ja not_active Expired - Fee Related
- 2008-05-08 EP EP08769338A patent/EP2146946B1/en active Active
- 2008-05-08 RU RU2009145537/04A patent/RU2470908C2/ru not_active IP Right Cessation
- 2008-05-08 PL PL10014318T patent/PL2301908T3/pl unknown
- 2008-05-08 PT PT08769338T patent/PT2146946E/pt unknown
- 2008-05-08 AT AT08769338T patent/ATE487685T1/de active
- 2008-05-08 PL PL08769338T patent/PL2146946T3/pl unknown
- 2008-05-08 DE DE602008003431T patent/DE602008003431D1/de active Active
- 2008-05-08 SI SI200831288T patent/SI2301908T1/sl unknown
- 2008-05-08 DK DK08769338.8T patent/DK2146946T3/da active
- 2008-05-08 EP EP14173149.7A patent/EP2810927A1/en not_active Withdrawn
- 2008-05-08 CN CN2008800153921A patent/CN101715437B/zh not_active Expired - Fee Related
- 2008-05-08 MX MX2009012124A patent/MX2009012124A/es active IP Right Grant
2009
- 2009-10-28 IL IL201795A patent/IL201795A0/en not_active IP Right Cessation
2010
- 2010-06-04 HK HK10105523.3A patent/HK1138829A1/xx not_active IP Right Cessation
- 2010-10-25 ZA ZA2010/07603A patent/ZA201007603B/en unknown
2011
- 2011-09-30 HK HK11110396.6A patent/HK1156019A1/xx not_active IP Right Cessation
- 2011-10-14 US US13/274,172 patent/US8242315B2/en not_active Expired - Fee Related
2012
- 2012-07-13 US US13/548,991 patent/US8575400B2/en not_active Expired - Fee Related
2013
- 2013-09-23 US US14/034,305 patent/US8871815B2/en not_active Expired - Fee Related
2014
- 2014-09-18 HR HRP20140896AT patent/HRP20140896T1/hr unknown

Also Published As

Publication number	Publication date
HRP20140896T1 (hr)	2015-01-02
DE602008003431D1 (de)	2010-12-23
AU2008251482C1 (en)	2014-04-03
WO2008141097A3 (en)	2008-12-31
JP5651009B2 (ja)	2015-01-07
US8071818B2 (en)	2011-12-06
CN101715437A (zh)	2010-05-26
EP2301908B1 (en)	2014-06-25
EP2301908A1 (en)	2011-03-30
EP2146946B1 (en)	2010-11-10
PT2146946E (pt)	2011-02-14
IL201795A0 (en)	2010-06-16
US20100292346A1 (en)	2010-11-18
MX2009012124A (es)	2010-02-18
RU2470908C2 (ru)	2012-12-27
JP2010526826A (ja)	2010-08-05
SI2301908T1 (sl)	2014-10-30
US20130059919A1 (en)	2013-03-07
US8242315B2 (en)	2012-08-14
EP2810927A1 (en)	2014-12-10
ES2501592T3 (es)	2014-10-02
KR20100017436A (ko)	2010-02-16
WO2008141097A9 (en)	2009-04-02
RU2009145537A (ru)	2011-06-20
US20120035271A1 (en)	2012-02-09
PL2301908T3 (pl)	2015-02-27
NZ580752A (en)	2012-03-30
US8871815B2 (en)	2014-10-28
WO2008141097A2 (en)	2008-11-20
HK1138829A1 (en)	2010-09-03
US8575400B2 (en)	2013-11-05
ATE487685T1 (de)	2010-11-15
AU2008251482A1 (en)	2008-11-20
CA2685570A1 (en)	2008-11-20
DK2301908T3 (da)	2014-09-15
US20140206773A1 (en)	2014-07-24
HK1156019A1 (en)	2012-06-01
CN101715437B (zh)	2013-06-12
ZA201007603B (en)	2012-08-29
EP2292577A1 (en)	2011-03-09
AU2008251482B2 (en)	2013-09-26
PL2146946T3 (pl)	2011-04-29
DK2146946T3 (da)	2011-02-14
EP2301908B8 (en)	2014-09-03
EP2146946A2 (en)	2010-01-27

Publication	Publication Date	Title
MX2009012125A (es)	2010-02-18	Compuestos terapeuticos.
CY1121699T1 (el)	2020-07-31	Ενωσεις τριαζινης ως αναστολεις κινασης ρ13 και mtor
CY1121543T1 (el)	2020-05-29	Ενωση πυριδυλαμινοοξεικου οξεος
CY1111481T1 (el)	2015-08-05	Υποκατεστημενα αρυλοκυκλοπροπυλακεταμιδια ως ενεργοποιητες γλυκοκινασης
MX2009009492A (es)	2009-09-15	Compuestos organicos biciclicos adecuados para el tratamiento de condiciones inflamatorias o alergicas.
PH12015502323A1 (en)	2019-08-19	Enantiomers of spiro-oxindole compounds and their uses as therapeutic agents
TW200728307A (en)	2007-08-01	Novel spirochromanone derivatives
SG171617A1 (en)	2011-06-29	Therapeutic compounds
MX358961B (es)	2018-09-10	Compuestos de tetraciclina sustituidos con fluor en c7.
RS52823B (en)	2013-10-31	NEW UNITS USEFUL FOR TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES
NZ592497A (en)	2013-02-22	Derivatives of 1-amino-2-cyclobutylethylboronic acid
MX2009003081A (es)	2009-04-01	Derivados de pirrola utiles para el tratamiento de enfermedades mediadas por citoquinas.
BRPI0811220A2 (pt)	2014-10-29	Compostos terapêuticos
IN2012DN02502A (pt)	2015-08-28
WO2010132670A3 (en)	2010-12-29	Pentacycline compounds
CU20100252A7 (es)	2011-11-15	Derivados de dibenzotiazepina
TW200700390A (en)	2007-01-01	Metabolites for nk-1 antagonists for emesis
MX2011012068A (es)	2012-06-08	Nucleosidos 2'-fluoro arabino y su utilizaicon.
EA200901085A1 (ru)	2010-02-26	Производные циклогексиламида арилкарбоновой кислоты
CY1117805T1 (el)	2017-05-17	Αντιμετωπιση οστεοπορωσης
CY1113057T1 (el)	2016-04-13	Αναστολεας συνδεσης s1ρ1
BRPI0514020A (pt)	2008-05-27	oxindóis oxazolidinonas como agentes antibacterianos

Legal Events

Date	Code	Title	Description
2015-06-23	B25D	Requested change of name of applicant approved	Owner name: SIGNATURE THERAPEUTICS, INC. (US)
2015-07-14	B25A	Requested transfer of rights approved	Owner name: SOWOOD HEALTHCARE LLC (US)
2016-09-20	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 8A ANUIDADE.
2017-01-10	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.
2022-07-12	B350	Update of information on the portal [chapter 15.35 patent gazette]