BRPI0809678A2 - Métodos - Google Patents

Métodos

Info

Publication number: BRPI0809678A2
Authority: BR; Brazil
Prior art keywords: methods
Prior art date: 2007-04-03

Application number

BRPI0809678-3A2A

Other languages

English (en)

Inventor

Gottfried Sedelmeier

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-04-03

Filing date

2008-04-01

Publication date

2014-10-07

2008-04-01 Application filed by Novartis Ag filed Critical Novartis Ag

2014-10-07 Publication of BRPI0809678A2 publication Critical patent/BRPI0809678A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
- C07C205/14—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to acyclic carbon atoms
- C07C205/15—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/28—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to acyclic carbon atoms of the carbon skeleton
- C07C205/29—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated
- C07C205/30—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated the oxygen atom of at least one of the etherified hydroxy groups being further bound to a carbon atom of a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/28—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to acyclic carbon atoms of the carbon skeleton
- C07C205/31—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/39—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
- C07C205/40—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups and esterified hydroxy groups bound to acyclic carbon atoms of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/44—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by —CHO groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/50—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
- C07C205/51—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/50—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
- C07C205/53—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/44—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reduction and hydrolysis of nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BRPI0809678-3A2A 2007-04-03 2008-04-01 Métodos BRPI0809678A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP07105572		2007-04-03
PCT/EP2008/053891 WO2008119804A1 (en)	2007-04-03	2008-04-01	New methods

Publications (1)

Publication Number	Publication Date
BRPI0809678A2 true BRPI0809678A2 (pt)	2014-10-07

Family

ID=38462036

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0809678-3A2A BRPI0809678A2 (pt)	2007-04-03	2008-04-01	Métodos

Country Status (19)

Country	Link
US (1)	US8338620B2 (pt)
EP (1)	EP2142497A1 (pt)
JP (1)	JP2010523523A (pt)
KR (1)	KR20100016137A (pt)
CN (1)	CN101679213A (pt)
AU (1)	AU2008234834B2 (pt)
BR (1)	BRPI0809678A2 (pt)
CA (1)	CA2681203A1 (pt)
CO (1)	CO6231027A2 (pt)
EC (1)	ECSP099708A (pt)
GT (1)	GT200900259A (pt)
IL (1)	IL201054A0 (pt)
MA (1)	MA31325B1 (pt)
MX (1)	MX2009010699A (pt)
NZ (1)	NZ579792A (pt)
RU (1)	RU2009140306A (pt)
TN (1)	TN2009000401A1 (pt)
WO (1)	WO2008119804A1 (pt)
ZA (1)	ZA200906490B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ571300A (en)	2006-04-07	2011-12-22	Warner Chilcott Co Llc	Antibodies that bind human protein tyrosine phosphatase beta (HPTPBeta) and uses thereof
EP2189442B1 (en) *	2008-11-20	2014-10-01	Krka Tovarna Zdravil, D.D., Novo Mesto	Process and intermediates for the preparation of aliskiren
US8779198B2 (en) *	2009-08-11	2014-07-15	Novartis Ag	Ring opening of lactones and lactams
WO2011048523A1 (en) *	2009-10-21	2011-04-28	CarboDesign LLC	Process for the manufacture of enantiomerically pure aryloctanoic acids as aliskiren
WO2011051853A1 (en) *	2009-10-29	2011-05-05	CarboDesign LLC	Manufacturing process for preparing enaniomerically pure 8- aryloctanoic acid derivatives such as aliskiren
WO2011064790A1 (en) *	2009-11-30	2011-06-03	Avra Laboratories Pvt. Ltd	A novel process for making aliskiren, its novel intermediates and certain novel compounds
EP2523934A1 (en) *	2010-02-10	2012-11-21	Ratiopharm GmbH	Salts of aliskiren
CN102241650B (zh) *	2010-05-14	2014-05-07	浙江九洲药业股份有限公司	用于制备阿立克仑的中间体化合物及相关制备方法
CN102485722B (zh) *	2010-12-06	2014-05-07	博瑞生物医药技术(苏州)有限公司	阿利克仑、其中间体和药用盐及制备方法
US8703976B2 (en)	2011-10-02	2014-04-22	Milan Soukup	Manufacturing process for 8-aryloctanoic acids such as Aliskiren
US10087190B1 (en) *	2017-04-24	2018-10-02	Purdue Research Foundation	Lactones

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4219660A (en) *	1977-06-24	1980-08-26	Hoffmann-La Roche Inc.	Conjugated diene derivatives
US5606078A (en) *	1994-04-18	1997-02-25	Ciba-Geigy Corporation	3,5-Disubstituted tetrahydrofuran-2-ones
MY119161A (en) *	1994-04-18	2005-04-30	Novartis Ag	Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities
US5659065A (en) *	1994-04-18	1997-08-19	Novartis Corporation	Alpha-aminoalkanoic acids and reduction products
JP2004517805A (ja) *	2000-06-30	2004-06-17	ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー	ケモカイン受容体活性調節剤としてのｎ−ウレイドヘテロシクロアルキル−ピペリジン
EP1758899A1 (en) *	2004-06-03	2007-03-07	Brandeis University	Asymmetric michael and aldol addition using bifunctional cinchona-alkaloid-based catalysts
JP4639327B2 (ja) *	2004-07-16	2011-02-23	国立大学法人高知大学	光学活性アミノピリジル基含有ピロリジン誘導体及びそれを用いた不斉合成方法
JP4775915B2 (ja) *	2005-07-29	2011-09-21	長瀬産業株式会社	グアニジン−チオウレア化合物およびそれを用いたニトロアルコールの製造方法
GB0521083D0 (en)	2005-10-17	2005-11-23	Novartis Ag	Organic compounds

2008
- 2008-04-01 MX MX2009010699A patent/MX2009010699A/es not_active Application Discontinuation
- 2008-04-01 BR BRPI0809678-3A2A patent/BRPI0809678A2/pt not_active IP Right Cessation
- 2008-04-01 EP EP08735661A patent/EP2142497A1/en not_active Withdrawn
- 2008-04-01 NZ NZ579792A patent/NZ579792A/en not_active IP Right Cessation
- 2008-04-01 WO PCT/EP2008/053891 patent/WO2008119804A1/en active Application Filing
- 2008-04-01 CN CN200880015223A patent/CN101679213A/zh active Pending
- 2008-04-01 AU AU2008234834A patent/AU2008234834B2/en not_active Ceased
- 2008-04-01 US US12/594,414 patent/US8338620B2/en not_active Expired - Fee Related
- 2008-04-01 CA CA002681203A patent/CA2681203A1/en not_active Abandoned
- 2008-04-01 JP JP2010501501A patent/JP2010523523A/ja active Pending
- 2008-04-01 RU RU2009140306/04A patent/RU2009140306A/ru not_active Application Discontinuation
- 2008-04-01 KR KR1020097022892A patent/KR20100016137A/ko not_active Application Discontinuation
2009
- 2009-09-17 ZA ZA200906490A patent/ZA200906490B/xx unknown
- 2009-09-21 IL IL201054A patent/IL201054A0/en unknown
- 2009-10-01 GT GT200900259A patent/GT200900259A/es unknown
- 2009-10-01 CO CO09107976A patent/CO6231027A2/es not_active Application Discontinuation
- 2009-10-02 TN TNP2009000401A patent/TN2009000401A1/fr unknown
- 2009-10-21 MA MA32298A patent/MA31325B1/fr unknown
- 2009-10-30 EC EC2009009708A patent/ECSP099708A/es unknown

Also Published As

Publication number	Publication date
IL201054A0 (en)	2010-05-17
KR20100016137A (ko)	2010-02-12
ZA200906490B (en)	2010-05-26
CN101679213A (zh)	2010-03-24
US8338620B2 (en)	2012-12-25
ECSP099708A (es)	2009-11-30
GT200900259A (es)	2010-03-15
EP2142497A1 (en)	2010-01-13
US20100130749A1 (en)	2010-05-27
TN2009000401A1 (en)	2011-03-31
CO6231027A2 (es)	2010-12-20
WO2008119804A1 (en)	2008-10-09
CA2681203A1 (en)	2008-10-09
AU2008234834A1 (en)	2008-10-09
MX2009010699A (es)	2010-03-10
JP2010523523A (ja)	2010-07-15
NZ579792A (en)	2012-03-30
MA31325B1 (fr)	2010-04-01
AU2008234834B2 (en)	2012-01-19
RU2009140306A (ru)	2011-05-10

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NO2022048I1 (no)	2022-11-16	onasemnogene abeparvovec
NO2019037I1 (no)	2019-10-16	pegvaliase
DK2205737T3 (da)	2013-05-21	Mikromirer
BRPI0821573A2 (pt)	2016-08-09	benzofuropirimidonas
ATE501136T1 (de)	2011-03-15	Imidazopyridinone
ATE514696T1 (de)	2011-07-15	Diphenyl-dihydro-imidazopyridinone
DE112008003636A5 (de)	2010-10-21	Mehrzuggruppierer
DE502007001207D1 (de)	2009-09-10	Elektrosaugkopf
BRPI0814519A2 (pt)	2014-09-30	Organopolissiloxano
BRPI0811451A2 (pt)	2014-11-04	Exopolissacarídeo
BRPI0812840A2 (pt)	2014-12-09	2-imidazolinas
BRPI0815547A2 (pt)	2015-02-10	Depsipeptídeos cícliocos
AT505058A3 (de)	2008-12-15	Türschliesssystem
BRPI0809678A2 (pt)	2014-10-07	Métodos
BRPI0812994A2 (pt)	2014-12-23	Microbiocidas
DE602008005950D1 (de)	2011-05-19	Münzvereinzeler
DE112008001216A5 (de)	2010-02-04	Magnetronplasmaanlage
DE112008003094A5 (de)	2010-08-12	Geomatte
DE112008003196A5 (de)	2011-02-03	Handpipettiergerät
DE112008002200A5 (de)	2010-09-23	Sperrsynchronisiervorrichtung
CU20090155A7 (es)	2011-04-26	Macrolidos
DE102007038931A8 (de)	2009-06-18	Fadenlagennähwirkstoffe
FI20075609A0 (fi)	2007-09-05	Monilähetysvastaanottolaite
FI20075115A (fi)	2008-08-17	Tuloilmayksikkö

Legal Events

Date	Code	Title	Description
2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 6A E 7A ANUIDADES.
2016-03-29	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.