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BR9911223A - Proteìnas de ligação à angiostatina, peptìdeos de ligação a um fragmento n-terminal do plasminogênio, ácidos nucleicos codificantes das referidas proteìnas e peptìdeos, vetores compreendendo o referidos ácidos nucleicos, células recombinantes contendo os referidos vetores, anticorpos que se ligam às referidas proteìnas ou peptìdeos, células recombinantes que expressam os referidos anticorpos , método de varredura de compostos capazes de interagir com as referidas proteìnas, compostos identificados pelo referido método, uso das referidas proteìnas, peptìdeos ou compostos na preparação de medicamentos para o tratamento de doença ou desordem relacionada à angiogênese e preparação farmacêutica contendo as referidas proteìnas, peptìdeos ou compostos. - Google Patents

Proteìnas de ligação à angiostatina, peptìdeos de ligação a um fragmento n-terminal do plasminogênio, ácidos nucleicos codificantes das referidas proteìnas e peptìdeos, vetores compreendendo o referidos ácidos nucleicos, células recombinantes contendo os referidos vetores, anticorpos que se ligam às referidas proteìnas ou peptìdeos, células recombinantes que expressam os referidos anticorpos , método de varredura de compostos capazes de interagir com as referidas proteìnas, compostos identificados pelo referido método, uso das referidas proteìnas, peptìdeos ou compostos na preparação de medicamentos para o tratamento de doença ou desordem relacionada à angiogênese e preparação farmacêutica contendo as referidas proteìnas, peptìdeos ou compostos.

Info

Publication number
BR9911223A
BR9911223A BR9911223-0A BR9911223A BR9911223A BR 9911223 A BR9911223 A BR 9911223A BR 9911223 A BR9911223 A BR 9911223A BR 9911223 A BR9911223 A BR 9911223A
Authority
BR
Brazil
Prior art keywords
proteins
peptides
compounds
antibodies
vectors
Prior art date
Application number
BR9911223-0A
Other languages
English (en)
Inventor
Lars Holmgren
Boris Troyanovsky
Original Assignee
Pharmacia & Upjohn Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9802130A external-priority patent/SE9802130D0/xx
Priority claimed from SE9804372A external-priority patent/SE9804372D0/xx
Application filed by Pharmacia & Upjohn Ab filed Critical Pharmacia & Upjohn Ab
Publication of BR9911223A publication Critical patent/BR9911223A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

MOLéCULAS RELACIONADAS à ANGIOGêNESE A presente invenção proporciona a sequência de uma proteína capaz de agir como um receptor de Angiostatina, bem como a sequência nucleotídica do gene que codifica a mesma. A invenção também se relaciona ao uso das mesmas em métodos de varredura, em que novas substâncias são criadas exibindo as mesmas e vantajosas propriedades anti-angiogênicas da Angiostatina.
BR9911223-0A 1998-06-15 1999-06-11 Proteìnas de ligação à angiostatina, peptìdeos de ligação a um fragmento n-terminal do plasminogênio, ácidos nucleicos codificantes das referidas proteìnas e peptìdeos, vetores compreendendo o referidos ácidos nucleicos, células recombinantes contendo os referidos vetores, anticorpos que se ligam às referidas proteìnas ou peptìdeos, células recombinantes que expressam os referidos anticorpos , método de varredura de compostos capazes de interagir com as referidas proteìnas, compostos identificados pelo referido método, uso das referidas proteìnas, peptìdeos ou compostos na preparação de medicamentos para o tratamento de doença ou desordem relacionada à angiogênese e preparação farmacêutica contendo as referidas proteìnas, peptìdeos ou compostos. BR9911223A (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8926698P 1998-06-15 1998-06-15
SE9802130A SE9802130D0 (sv) 1998-06-15 1998-06-15 Angiogenesis related molecules
SE9804372A SE9804372D0 (sv) 1998-12-17 1998-12-17 Angiogenesis related molecules
US11438698P 1998-12-29 1998-12-29
PCT/EP1999/004109 WO1999066038A1 (en) 1998-06-15 1999-06-11 Angiostatin-binding protein

Publications (1)

Publication Number Publication Date
BR9911223A true BR9911223A (pt) 2001-03-06

Family

ID=27484811

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9911223-0A BR9911223A (pt) 1998-06-15 1999-06-11 Proteìnas de ligação à angiostatina, peptìdeos de ligação a um fragmento n-terminal do plasminogênio, ácidos nucleicos codificantes das referidas proteìnas e peptìdeos, vetores compreendendo o referidos ácidos nucleicos, células recombinantes contendo os referidos vetores, anticorpos que se ligam às referidas proteìnas ou peptìdeos, células recombinantes que expressam os referidos anticorpos , método de varredura de compostos capazes de interagir com as referidas proteìnas, compostos identificados pelo referido método, uso das referidas proteìnas, peptìdeos ou compostos na preparação de medicamentos para o tratamento de doença ou desordem relacionada à angiogênese e preparação farmacêutica contendo as referidas proteìnas, peptìdeos ou compostos.

Country Status (23)

Country Link
EP (1) EP1088069B1 (pt)
JP (1) JP2002518008A (pt)
KR (1) KR20010052887A (pt)
CN (2) CN1170931C (pt)
AR (1) AR019862A1 (pt)
AT (1) ATE295417T1 (pt)
AU (2) AU769933B2 (pt)
BR (1) BR9911223A (pt)
CA (1) CA2330228A1 (pt)
CY (1) CY1105675T1 (pt)
CZ (1) CZ20004671A3 (pt)
DE (1) DE69925271T2 (pt)
EA (1) EA200100037A1 (pt)
ES (1) ES2242400T3 (pt)
HU (1) HUP0102758A2 (pt)
ID (1) ID28136A (pt)
IL (2) IL139873A0 (pt)
NO (1) NO20006192L (pt)
PL (1) PL344979A1 (pt)
PT (1) PT1088069E (pt)
TR (1) TR200003695T2 (pt)
TW (1) TWI243852B (pt)
WO (1) WO1999066038A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040022788A1 (en) 1998-05-19 2004-02-05 Moser Tammy L. Compositions and methods for promoting or inhibiting angiogenesis
WO1999059620A1 (en) 1998-05-19 1999-11-25 Duke University Angiostatin receptor
US20040248138A1 (en) * 2001-11-01 2004-12-09 Mark Shannon Human angiomotin-like protein 1
US7129063B2 (en) 2001-11-16 2006-10-31 Eisai Co., Ltd. Exocrine gland tight junction-constituting protein jeap family
AU2003265559A1 (en) 2002-08-16 2004-03-03 Duke University Identification of the endothelial receptor for the angiostatin kringle-5
GB0330079D0 (en) * 2003-12-20 2004-02-04 Bioinvent Int Ab Vaccine
WO2007110209A1 (en) * 2006-03-29 2007-10-04 Bioinvent International Ab Biological materials and uses thereof
CN104878094B (zh) * 2015-04-30 2019-01-15 北京大北农科技集团股份有限公司 用于检测除草剂耐受性玉米植物dbn9888的核酸序列及其检测方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8501682A (nl) * 1985-06-11 1987-01-02 Tno Nieuw, uit bloed geisoleerd eiwit, werkwijze ter bereiding van dit eiwit, antilichamen tegen het nieuwe eiwit en farmaceutische preparaten, die het eiwit of de antilichamen bevatten.

Also Published As

Publication number Publication date
EP1088069B1 (en) 2005-05-11
NO20006192L (no) 2001-02-14
IL139873A0 (en) 2002-02-10
WO1999066038A1 (en) 1999-12-23
DE69925271T2 (de) 2006-02-23
JP2002518008A (ja) 2002-06-25
AU2004201999B2 (en) 2007-06-21
HUP0102758A2 (hu) 2001-11-28
EA200100037A1 (ru) 2001-06-25
AR019862A1 (es) 2002-03-20
CN1626552A (zh) 2005-06-15
CA2330228A1 (en) 1999-12-23
CN1170931C (zh) 2004-10-13
AU4513499A (en) 2000-01-05
TWI243852B (en) 2005-11-21
ID28136A (id) 2001-05-03
PL344979A1 (en) 2001-11-19
ES2242400T3 (es) 2005-11-01
CY1105675T1 (el) 2010-12-22
EP1088069A1 (en) 2001-04-04
CZ20004671A3 (cs) 2001-10-17
TR200003695T2 (tr) 2001-06-21
CN1305527A (zh) 2001-07-25
AU769933B2 (en) 2004-02-12
KR20010052887A (ko) 2001-06-25
NO20006192D0 (no) 2000-12-06
ATE295417T1 (de) 2005-05-15
AU2004201999A1 (en) 2004-06-10
IL139873A (en) 2008-08-07
PT1088069E (pt) 2005-09-30
DE69925271D1 (de) 2005-06-16

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B25C Requirement related to requested transfer of rights

Owner name: PHARMACIA AND UPJOHN AB (SE)

Free format text: A FIM DE ATENDER A PETICAO DE TRANSFERENCIA NO 020040014230/RJ DE 03/12/2004, CABE AO REQUERENTE APRESENTAR AS GUIAS DE RECOLHIMENTO REFERENTE A OUTRAS DUAS TRANSFERENCIAS, UMA VEZ QUE FORAM APRESENTADAS 03 DOCUMENTOS DE CESSAO, COMO TAMBEM DEVERA CONSTAR NO DOCUMENTO DE CESSAO A DEVIDA LEGALIZACAO CONSULAR.

B25A Requested transfer of rights approved

Owner name: LARS HOLMGREN (SE) , BORIS TROYANOVSKY (SE)

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08G Application fees: restoration [chapter 8.7 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements