BR9508249A - Processo para preparação de 2-(1-azabiciclo(2.2.2)oct-3-il)-2,4,5,6-tetraidro-1hbenz(de)isoquinolin-1-ona e produto intermediário - Google Patents

Processo para preparação de 2-(1-azabiciclo(2.2.2)oct-3-il)-2,4,5,6-tetraidro-1hbenz(de)isoquinolin-1-ona e produto intermediário

Info

Publication number: BR9508249A
Authority: BR; Brazil
Prior art keywords: isoquinolin; azabicyclo; tetrahydro; oct; preparing
Prior art date: 1994-07-08

Application number

BR9508249A

Other languages

English (en)

Inventor

Charles Alois Dvorak

Bruce Andrew Kowalczyk

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-07-08

Filing date

1995-07-01

Publication date

1998-01-06

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23040964&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9508249(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-07-01 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1998-01-06 Publication of BR9508249A publication Critical patent/BR9508249A/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BR9508249A 1994-07-08 1995-07-01 Processo para preparação de 2-(1-azabiciclo(2.2.2)oct-3-il)-2,4,5,6-tetraidro-1hbenz(de)isoquinolin-1-ona e produto intermediário BR9508249A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/272,715 US5567818A (en)	1994-07-08	1994-07-08	Processes for preparing 2-(1-azabicyclo[2.2.2]oct-3-yl)-1H-benz[de] isoquinolin-1-one derivatives and intermediates useful therein
PCT/EP1995/002556 WO1996001824A1 (en)	1994-07-08	1995-07-01	Process for the preparation of 2-(1-azabicyclo(2.2.2)oct-3-yl) -2,4,5,6-tetrahydro-1h-benz(de)isoquinolin-1-one and intermediate product

Publications (1)

Publication Number	Publication Date
BR9508249A true BR9508249A (pt)	1998-01-06

Family

ID=23040964

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9508249A BR9508249A (pt)	1994-07-08	1995-07-01	Processo para preparação de 2-(1-azabiciclo(2.2.2)oct-3-il)-2,4,5,6-tetraidro-1hbenz(de)isoquinolin-1-ona e produto intermediário

Country Status (16)

Country	Link
US (1)	US5567818A (pt)
EP (1)	EP0770077B1 (pt)
JP (1)	JP2898758B2 (pt)
CN (1)	CN1048727C (pt)
AT (1)	ATE205845T1 (pt)
AU (1)	AU2979995A (pt)
BR (1)	BR9508249A (pt)
CL (2)	CL2004001244A1 (pt)
CY (1)	CY2342B1 (pt)
DE (1)	DE69522808T2 (pt)
DK (1)	DK0770077T3 (pt)
ES (1)	ES2162929T3 (pt)
FI (1)	FI120198B (pt)
MX (1)	MX9700157A (pt)
PT (1)	PT770077E (pt)
WO (1)	WO1996001824A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE489211T1 (de)	2000-04-20	2010-12-15	Masonite Corp	Umgekehrtes geformtes paneel
JO2735B1 (en) *	2003-01-30	2013-09-15	هيلسين هيلث كير أس ايه.	Liquid pharmaceutical formations of balloonosterone
US8598219B2 (en)	2003-01-30	2013-12-03	Helsinn Healthcare Sa	Liquid pharmaceutical formulations of palonosetron
US8614225B2 (en) *	2006-08-30	2013-12-24	Dr. Reddy's Laboratories Limited	Process for the purification of palonosetron or its salt
WO2008051539A2 (en) *	2006-10-23	2008-05-02	Sicor Inc.	Processes for preparing palonosetron salts
EP2099298A4 (en) *	2006-12-07	2010-01-06	Helsinn Healthcare Sa	CRYSTALLINE AND AMORPHOUS FORMS OF PALONOSETRON HYDROCHLORIDE
WO2008146283A2 (en) *	2007-05-29	2008-12-04	Chemagis Ltd.	Novel palonosetron salts and processes for preparation and purification thereof
WO2009010987A1 (en) *	2007-07-19	2009-01-22	Natco Pharma Limited	An improved process for the preparation of pure palonosetron hydrochloride
AR069625A1 (es) *	2007-12-13	2010-02-03	Glenmark Generics Ltd	Base libre de palonosetron y procedimiento para su preparacion
WO2009087643A1 (en) *	2008-01-11	2009-07-16	Natco Pharma Limited	Novel crystalline forms of palonosetron hydrochloride
WO2009136405A1 (en) *	2008-05-05	2009-11-12	Natco Pharma Limited	High purity palonosetron base and its solid state characteristics
EP2364312A4 (en) *	2008-11-11	2012-05-02	Reddys Lab Ltd Dr	SYNTHESIS OF CRYSTALLINE PALONOSETRON CHLORHYDRATE
CN101851233B (zh) *	2009-04-03	2013-03-06	四川滇虹医药开发有限公司	盐酸帕洛诺司琼和其前体化合物及制备
WO2011001400A2 (en)	2009-06-30	2011-01-06	Ranbaxy Laboratories Limited	Processes for the preparation of form i and form ii of palonosetron hydrochloride
WO2011013095A1 (en)	2009-07-31	2011-02-03	Ranbaxy Laboratories Limited	Processes for the preparation of palonosetron
JP2014070036A (ja) *	2012-09-28	2014-04-21	Mitsubishi Gas Chemical Co Inc	１，８−テトラリンジカルボン酸無水物の製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4007191A (en) *	1975-10-14	1977-02-08	E. R. Squibb & Sons, Inc.	2-(Piperidinyl or tetrahydropyridinyl)-alkyl)-2,3-dihydro-3-hydroxy-1H-benz(DE)isoquinolin-1-ones
ZA909529B (en) *	1989-11-28	1992-08-26	Syntex Inc	New tricyclic compounds
US5202318A (en) *	1990-05-14	1993-04-13	Syntex (U.S.A.) Inc.	Tricyclic compounds acting at serotonin receptor subtypes

1994
- 1994-07-08 US US08/272,715 patent/US5567818A/en not_active Expired - Lifetime
1995
- 1995-07-01 AU AU29799/95A patent/AU2979995A/en not_active Abandoned
- 1995-07-01 BR BR9508249A patent/BR9508249A/pt active IP Right Grant
- 1995-07-01 DK DK95925803T patent/DK0770077T3/da active
- 1995-07-01 JP JP8504091A patent/JP2898758B2/ja not_active Expired - Lifetime
- 1995-07-01 MX MX9700157A patent/MX9700157A/es unknown
- 1995-07-01 EP EP95925803A patent/EP0770077B1/en not_active Expired - Lifetime
- 1995-07-01 CN CN95194002A patent/CN1048727C/zh not_active Expired - Lifetime
- 1995-07-01 PT PT95925803T patent/PT770077E/pt unknown
- 1995-07-01 ES ES95925803T patent/ES2162929T3/es not_active Expired - Lifetime
- 1995-07-01 AT AT95925803T patent/ATE205845T1/de active
- 1995-07-01 WO PCT/EP1995/002556 patent/WO1996001824A1/en active IP Right Grant
- 1995-07-01 DE DE69522808T patent/DE69522808T2/de not_active Expired - Lifetime
1997
- 1997-01-07 FI FI970068A patent/FI120198B/fi not_active IP Right Cessation
2003
- 2003-03-18 CY CY0300029A patent/CY2342B1/xx unknown
2004
- 2004-05-20 CL CL200401244A patent/CL2004001244A1/es unknown
2007
- 2007-07-05 CL CL200701958A patent/CL2007001958A1/es unknown

Also Published As

Publication number	Publication date
CL2007001958A1 (es)	2008-02-22
AU2979995A (en)	1996-02-09
CL2004001244A1 (es)	2005-04-15
JP2898758B2 (ja)	1999-06-02
PT770077E (pt)	2002-02-28
EP0770077A1 (en)	1997-05-02
ATE205845T1 (de)	2001-10-15
EP0770077B1 (en)	2001-09-19
DK0770077T3 (da)	2002-01-14
JPH09508645A (ja)	1997-09-02
ES2162929T3 (es)	2002-01-16
US5567818A (en)	1996-10-22
FI970068A (fi)	1997-01-07
FI120198B (fi)	2009-07-31
DE69522808T2 (de)	2002-04-04
CN1152313A (zh)	1997-06-18
CN1048727C (zh)	2000-01-26
DE69522808D1 (de)	2001-10-25
MX9700157A (es)	1997-04-30
FI970068A0 (fi)	1997-01-07
WO1996001824A1 (en)	1996-01-25
CY2342B1 (en)	2004-02-06

Publication	Publication Date	Title
CL2007001958A1 (es)	2008-02-22	Procedimiento para preparar 2-(1-azabiciclo-[2.2.2]oct-3-il)-2,4,5,6-tetrahidro-1h-benz[de]isoquinolin-1-ona, sus sales y estereoisomeros individuales (divisional sol.1244-04).
BR9706827A (pt)	1999-03-23	Processo aperfeiçoado para amaciar polpa e produtos de polpa produzidos pelo mesmo
BR9510581A (pt)	1999-01-05	Processo para preparação de etilbenzeno ou etilbenzeno substituído
BR9007058A (pt)	1991-11-12	Processo aperfeicoado de hidrogenolise/desidroalogenacao
BR9709241A (pt)	1999-08-10	Processo para a produção de 1,4-butanodiol gama-butirolactona e tetraidrofurano
BR9004791A (pt)	1991-09-10	Filtro,filtro composito e processo de formacao de um filtro
ITMI932443A0 (it)	1993-11-17	Processo per preparare perfluoropolietri
ITMI921488A1 (it)	1993-12-17	Granulati, processo per la loro preparazione e loro impiego
PT879228E (pt)	2003-01-31	Processo para a preparacao de d-treo-(r,r)-metilfenidato e reciclagem de enantiomeros indesejaveis por epimerizacao
BR9406126A (pt)	1996-02-13	Produto pseudo-dipeptícico,processo químico e enzimático de preparação do mesmo aplicação do produto e medicamento
BR9611339A (pt)	1999-04-06	Processo de preparação de 1,3-propanediol
PT789767E (pt)	2003-11-28	Processo para a producao de proteinas de papilomavirus purificadas
BR9607413A (pt)	1998-06-23	Processo para produçao de pentafluoretano e tetrafluorcloroetano
BR9605576A (pt)	1998-08-18	Processo para produçao de um concentrado de tinta
BR9504451A (pt)	1997-05-20	Processo de produçao de um aço acalmado por aluminio em estado de fusao
BR9102048A (pt)	1992-04-28	Composito,composito para calha de movimentacao dos vidros de um veiculo e processo para a formacao de um composito
BR9400338A (pt)	1994-08-16	Processo para preparação de 1,1,1,2-tetrafluoro-2-cloroetano e de pentafluoretano
PT874822E (pt)	2004-02-27	Novo processo de producao
BR9602005A (pt)	1998-10-06	Processo de hidroxicarbonilação de butadieno
BR9601278A (pt)	1998-01-13	Processo para produzir agentes de acilação
BR9607371A (pt)	1997-12-30	Processo para produção de eletrodos de carbono
BR9612064A (pt)	1999-02-23	Processo para preparação de esteróides 9,11-beta-epóxido
BR9404149A (pt)	1995-06-20	Processo de hidroxicarbonilação do butadieno
BR9405176A (pt)	1995-08-01	Processo e máquino para realização de cigarros ventilados
BR8905832A (pt)	1991-05-21	Processo para producao de ferro-gusa em fusao

Legal Events

Date	Code	Title	Description
2004-07-27	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2004-12-21	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2005-06-21	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2005-09-27	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/09/2005, OBSERVADAS AS CONDICOES LEGAIS.
2013-10-08	B22O	Other matters related to patents and certificates of addition of invention: legal action concerning patent	Free format text: INPI-52400.061552/2013 ORIGEM: JUIZO DA 013A VARA FEDERAL DO RIO DE JANEIRO PROCESSO NO 0132261-03.2013.4.02.5101 ACAO DE NULIDADE DAS PATENTES SUBMETIDAS AO MAILBOX (ART. 229, PARAGRAFO UNICO DA LPI); ALTERNATIVAMENTE, A DECRETACAO DA NULIDADE PARCIAL PARA CORRECAO DO PRAZO DE VIGENCIA; SUBSIDIARIAMENTE, CASO SE ENTENDA NAO SER O CASO DE NULIDADE, A CORRECAO DO ATO ADMINISTRATIVO PARA ADEQUACAO DA VIGENCIA DAS PATENTES. AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU: ELI LILLY AND COMPANY (NZ) LIMITED, ELI LILLY AND COMPANY, F. HOFFMANN-LA ROCHE AG., GENENTECH, INC. E HOECHST AKTIENGESELLSCHAFT
2021-08-10	B19A	Notification of judicial decision: notification of judicial decision	Free format text: PROCESSO INPI NO 52400.061552/2013-16 PROCESSO: 0132261-03.2013.4.02.5101 (2013.51.01.132261-9) 31A VARA FEDERAL DO RIO DE JANEIRO AUTOR: INPI-INSTITUTO NACIONAL DE PROPRIEDADE INDUSTRIAL REU: ELI LILLY AND COMPANY (NZ) LIMITED E OUTROS DECISAO: DECRETACAO DA NULIDADE PARCIAL DAS PATENTES PI 9508249-2 E PI 9603619-2, DE TITULARIDADE DA F HOFFMANN ? LA ROCHE AG, APENAS NO QUE SE REFERE AO PRAZO DE VIGENCIA DAS MESMAS, PARA DETERMINAR A ADEQUACAO DAS PATENTES PARA VINTE ANOS CONTADOS A PARTIR DA DATA DO RESPECTIVO DEPOSITO, NOS TERMOS DO PARAGRAFO UNICO DO ART. 229 C/C O CAPUT DO ART. 40, AMBOS DA LEI 9.279/96. TRANSITO EM JULGADO.