BR9102699A - N-oxidos de piridina 2,4-e 2,5-substituidos; processo para a sua producao e sua utilizacao, bem como composicao farmaceutica e processo para sua producao - Google Patents

N-oxidos de piridina 2,4-e 2,5-substituidos; processo para a sua producao e sua utilizacao, bem como composicao farmaceutica e processo para sua producao

Info

Publication number: BR9102699A
Authority: BR; Brazil
Prior art keywords: production; oxides; pyridine; replaced; well
Prior art date: 1990-06-28

Application number

BR919102699A

Other languages

English (en)

Inventor

Ekkehard Dr Baader

Martin Dr Bickel

Volkmar Dr Guenzler-Pukall

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-28

Filing date

1991-06-27

Publication date

1992-02-04

1991-06-27 Application filed by Hoechst Ag filed Critical Hoechst Ag

1992-02-04 Publication of BR9102699A publication Critical patent/BR9102699A/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Diabetes (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Transplantation (AREA)
Pulmonology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicinal Preparation (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

BR919102699A 1990-06-28 1991-06-27 N-oxidos de piridina 2,4-e 2,5-substituidos; processo para a sua producao e sua utilizacao, bem como composicao farmaceutica e processo para sua producao BR9102699A (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4020570A DE4020570A1 (de)	1990-06-28	1990-06-28	2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung

Publications (1)

Publication Number	Publication Date
BR9102699A true BR9102699A (pt)	1992-02-04

Family

ID=6409247

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR919102699A BR9102699A (pt)	1990-06-28	1991-06-27	N-oxidos de piridina 2,4-e 2,5-substituidos; processo para a sua producao e sua utilizacao, bem como composicao farmaceutica e processo para sua producao

Country Status (27)

Country	Link
EP (1)	EP0463592B1 (pt)
JP (1)	JPH0832687B2 (pt)
KR (1)	KR920000724A (pt)
CN (1)	CN1038585C (pt)
AT (1)	ATE110059T1 (pt)
AU (1)	AU636990B2 (pt)
BR (1)	BR9102699A (pt)
CA (1)	CA2045868A1 (pt)
CZ (1)	CZ283782B6 (pt)
DE (2)	DE4020570A1 (pt)
DK (1)	DK0463592T3 (pt)
EG (1)	EG19851A (pt)
ES (1)	ES2061118T3 (pt)
FI (1)	FI101070B (pt)
HR (1)	HRP940701B1 (pt)
HU (1)	HU214627B (pt)
IE (1)	IE65300B1 (pt)
IL (1)	IL98629A (pt)
LT (1)	LT3918B (pt)
MA (1)	MA22191A1 (pt)
MX (1)	MX26415A (pt)
MY (1)	MY107573A (pt)
NO (1)	NO178026C (pt)
NZ (1)	NZ238701A (pt)
PT (1)	PT98108B (pt)
YU (1)	YU113391A (pt)
ZA (1)	ZA914958B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
YU9492A (sh) *	1991-02-05	1995-03-27	Hoechst Ag.	2,4- i 2,5-bis-tetrazolilni piridini i postupak za njihovo dobijanje
CA2085954A1 (en) *	1991-12-24	1993-06-25	Klaus Weidmann	Substituted pyridine n-oxides, processes for their preparation, and their use
TW352384B (en) *	1992-03-24	1999-02-11	Hoechst Ag	Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals
TW222585B (pt) *	1992-09-11	1994-04-21	Hoechst Ag
DE4233124A1 (de) *	1992-10-02	1994-04-07	Hoechst Ag	Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE19624659A1 (de)	1996-06-20	1998-01-08	Klinge Co Chem Pharm Fab	Neue Pyridylalken- und Pyridylalkinsäureamide
DE19624704A1 (de)	1996-06-20	1998-01-08	Klinge Co Chem Pharm Fab	Neue Pyridylalkansäureamide
US6451816B1 (en)	1997-06-20	2002-09-17	Klinge Pharma Gmbh	Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression
FR2766187B1 (fr)	1997-07-17	2000-06-02	Rhone Poulenc Rorer Sa	Derives de pyrazine, leur preparation et les medicaments les contenant
DE19756235A1 (de)	1997-12-17	1999-07-01	Klinge Co Chem Pharm Fab	Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide
US6903118B1 (en)	1997-12-17	2005-06-07	Klinge Pharma Gmbh	Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides
DE19756261A1 (de)	1997-12-17	1999-07-01	Klinge Co Chem Pharm Fab	Neue arylsubstituierte Pyridylalkan-, alken- und alkincarbonsäureamide
DE19756212A1 (de)	1997-12-17	1999-07-01	Klinge Co Chem Pharm Fab	Neue, mit einem cyclischen Imid substituierte Pyridylalkan-, alken- und -alkincarbonsäureamide
EP1031564A1 (en)	1999-02-26	2000-08-30	Klinge Pharma GmbH	Inhibitors of cellular nicotinamide mononucleotide formation and their use in cancer therapy
DOP2002000333A (es)	2001-02-14	2002-09-30	Warner Lambert Co	Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz
DOP2002000332A (es)	2001-02-14	2002-08-30	Warner Lambert Co	Inhibidores de piridina de metaloproteinasas de la matriz
EP1368323B1 (en)	2001-02-14	2010-06-30	Warner-Lambert Company LLC	Pyrimidine matrix metalloproteinase inhibitors
US6924276B2 (en)	2001-09-10	2005-08-02	Warner-Lambert Company	Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors
WO2003032999A1 (en)	2001-10-12	2003-04-24	Warner-Lambert Company Llc	Alkyne matrix metalloproteinase inhibitors
US6933298B2 (en)	2001-12-08	2005-08-23	Aventis Pharma Deutschland Gmbh	Pyridine-2,4-dicarboxylic acid diamides and pyrimidine-4,6-dicarboxylic acid diamides and the use thereof for selectively inhibiting collagenases
DE10160357A1 (de) *	2001-12-08	2003-06-18	Aventis Pharma Gmbh	Verwendung von Pyridin-2,4-dicarbonsäurediamiden und Pyrimidin-4,6-dicarbonsäurediamiden zur selektiven Inhibierung von Kollagenasen

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5623987B2 (pt) *	1972-02-04	1981-06-03
JPS6052702B2 (ja)	1976-08-27	1985-11-20	中外製薬株式会社	ピリジン誘導体およびその製造方法
JPS57109792A (en) *	1980-12-26	1982-07-08	Banyu Pharmaceut Co Ltd	Penicillin derivative and salt thereof
DE3432094A1 (de)	1984-08-31	1986-03-06	Hoechst Ag, 6230 Frankfurt	Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase
JP2512924B2 (ja) *	1987-01-21	1996-07-03	萬有製薬株式会社	育毛剤
DE3703963A1 (de) *	1987-02-10	1988-08-18	Hoechst Ag	Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen
DE3703959A1 (de)	1987-02-10	1988-08-18	Hoechst Ag	Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE3703962A1 (de)	1987-02-10	1988-08-18	Hoechst Ag	Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
JP2600786B2 (ja) *	1988-04-12	1997-04-16	萬有製薬株式会社	育毛剤
DE3826471A1 (de)	1988-08-04	1990-02-22	Hoechst Ag	Verbessertes verfahren zur herstellung von n,n'-bis(alkoxyalkyl)-pyridin-2,4-dicarbonsaeurediamiden
DE3924093A1 (de)	1989-07-20	1991-02-07	Hoechst Ag	N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
ZA91291B (en)	1990-01-16	1991-09-25	Hoechst Ag	Di(nitroxyalkyl)amides of pyridine-2,4-and-2,5-dicarboxylic acids,a process for the preparation thereof,and the use thereof

1990
- 1990-06-28 DE DE4020570A patent/DE4020570A1/de not_active Withdrawn
1991
- 1991-06-22 DK DK91110343.0T patent/DK0463592T3/da active
- 1991-06-22 DE DE59102547T patent/DE59102547D1/de not_active Expired - Fee Related
- 1991-06-22 EP EP91110343A patent/EP0463592B1/de not_active Expired - Lifetime
- 1991-06-22 AT AT91110343T patent/ATE110059T1/de not_active IP Right Cessation
- 1991-06-22 ES ES91110343T patent/ES2061118T3/es not_active Expired - Lifetime
- 1991-06-26 FI FI913118A patent/FI101070B/fi active IP Right Grant
- 1991-06-26 CZ CS911959A patent/CZ283782B6/cs not_active IP Right Cessation
- 1991-06-26 MY MYPI91001142A patent/MY107573A/en unknown
- 1991-06-26 IL IL9862991A patent/IL98629A/en not_active IP Right Cessation
- 1991-06-26 NZ NZ238701A patent/NZ238701A/en unknown
- 1991-06-26 EG EG39291A patent/EG19851A/xx active
- 1991-06-27 HU HU912158A patent/HU214627B/hu not_active IP Right Cessation
- 1991-06-27 YU YU113391A patent/YU113391A/sh unknown
- 1991-06-27 BR BR919102699A patent/BR9102699A/pt not_active Application Discontinuation
- 1991-06-27 AU AU79356/91A patent/AU636990B2/en not_active Ceased
- 1991-06-27 IE IE225391A patent/IE65300B1/en unknown
- 1991-06-27 JP JP3156562A patent/JPH0832687B2/ja not_active Expired - Lifetime
- 1991-06-27 MA MA22469A patent/MA22191A1/fr unknown
- 1991-06-27 MX MX2641591A patent/MX26415A/es unknown
- 1991-06-27 ZA ZA914958A patent/ZA914958B/xx unknown
- 1991-06-27 CN CN91104308A patent/CN1038585C/zh not_active Expired - Fee Related
- 1991-06-27 NO NO912541A patent/NO178026C/no not_active IP Right Cessation
- 1991-06-27 PT PT98108A patent/PT98108B/pt not_active IP Right Cessation
- 1991-06-27 CA CA002045868A patent/CA2045868A1/en not_active Abandoned
- 1991-06-28 KR KR1019910010858A patent/KR920000724A/ko not_active Application Discontinuation
1993
- 1993-11-12 LT LTIP1464A patent/LT3918B/lt not_active IP Right Cessation
1994
- 1994-10-19 HR HRP-1133/91A patent/HRP940701B1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0463592A1 (de)	1992-01-02
LT3918B (en)	1996-04-25
NO178026B (no)	1995-10-02
CS195991A3 (en)	1992-02-19
NO178026C (no)	1996-01-10
EG19851A (en)	1996-10-31
ES2061118T3 (es)	1994-12-01
DK0463592T3 (da)	1994-12-19
CZ283782B6 (cs)	1998-06-17
FI913118A (fi)	1991-12-29
EP0463592B1 (de)	1994-08-17
MX26415A (es)	1993-05-01
LTIP1464A (en)	1995-05-25
AU7935691A (en)	1992-01-02
NO912541D0 (no)	1991-06-27
NZ238701A (en)	1994-06-27
IE912253A1 (en)	1992-01-01
YU113391A (sh)	1995-10-03
HUT59104A (en)	1992-04-28
AU636990B2 (en)	1993-05-13
NO912541L (no)	1991-12-30
HRP940701A2 (en)	1997-02-28
KR920000724A (ko)	1992-01-29
IL98629A0 (en)	1992-07-15
HU214627B (hu)	1998-04-28
FI101070B (fi)	1998-04-15
FI913118A0 (fi)	1991-06-26
CN1057649A (zh)	1992-01-08
JPH04230264A (ja)	1992-08-19
JPH0832687B2 (ja)	1996-03-29
CA2045868A1 (en)	1991-12-29
HU912158D0 (en)	1991-12-30
PT98108B (pt)	1998-12-31
DE59102547D1 (de)	1994-09-22
IE65300B1 (en)	1995-10-18
PT98108A (pt)	1993-06-30
CN1038585C (zh)	1998-06-03
ATE110059T1 (de)	1994-09-15
ZA914958B (en)	1992-03-25
DE4020570A1 (de)	1992-01-02
IL98629A (en)	1996-05-14
MA22191A1 (fr)	1991-12-31
MY107573A (en)	1996-04-30
HRP940701B1 (en)	1999-08-31

Publication	Publication Date	Title
BR9102699A (pt)	1992-02-04	N-oxidos de piridina 2,4-e 2,5-substituidos; processo para a sua producao e sua utilizacao, bem como composicao farmaceutica e processo para sua producao
BR8606430A (pt)	1987-10-20	Derivado de oxima de pirazol,processo para sua producao e composicao inseticida e acaricida
NO884170L (no)	1990-03-21	Katalytisk omdanningsprosess.
MX9206450A (es)	1993-05-01	Proceso para la produccion de isoleucina-l.
IT1164821B (it)	1987-04-15	Benzammidi eterocicliche sostituite procedimento per la loro produzione e loro impiego come modificatori di comportamento
HU905062D0 (en)	1991-01-28	Process for producing new 2-(rs)-substituted 2,3-dihydro-5-oxy-4,6,7-trimethyl-benzofurane compounds
NO884172L (no)	1990-03-21	Katalytisk omdanningsprosess.
ATE113591T1 (de)	1994-11-15	4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol- - one und ihre verwendung als antikonvulsiva.
PT88254A (pt)	1989-06-30	Processo para a preparacao de derivados de eritromicina a modificada em c.12
DE69606777D1 (de)	2000-03-30	Naphthamidderivate von 3-beta-amino azabicyclooctan oder nonan als antipsychotische arzneimittel
FR2772029B1 (fr)	2000-02-25	Procede de preparation de la mequitazine et nouvel intermediaire de synthese
ES2073495T3 (es)	1995-08-16	Benzotiazepinas.
DE59506045D1 (de)	1999-07-01	Verwendung von substituierten 6-amino-4h-pyranen
ATE100996T1 (de)	1994-02-15	Blattglanzmittel.
DE59103206D1 (de)	1994-11-17	Pressenanlage für das Herstellen von Pressteilen.
ATE100811T1 (de)	1994-02-15	Thienocinnolinverbindungen und deren verwendung als heilmittel.
ATE79788T1 (de)	1992-09-15	Schneidwalzenzerkleinerer.
ATE103657T1 (de)	1994-04-15	Tuerfluegel.
ATE104945T1 (de)	1994-05-15	Alkyltetramethylcyclohexan-derivate und deren verwendung als duftstoffe.
ATE80151T1 (de)	1992-09-15	2-(3-4-dihydroxyphenyl)-aethylamine, ihre herstellung und ihre verwendung als arzneimittel.
ATE58069T1 (de)	1990-11-15	Mineralischer stoff, verfahren zu seiner herstellung und verwendung desselben.
ES1015614Y (es)	1992-05-01	Util para masaje perfeccionado.

Legal Events

Date	Code	Title	Description
1999-01-26	EG	Technical examination (opinion): publication of technical examination (opinion)
1999-07-13	FC	Decision: refusal