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BR112022016909A2 - Métodos para a expansão de células t para o tratamento de câncer e malignidades associadas - Google Patents

Métodos para a expansão de células t para o tratamento de câncer e malignidades associadas

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Publication number
BR112022016909A2
BR112022016909A2 BR112022016909A BR112022016909A BR112022016909A2 BR 112022016909 A2 BR112022016909 A2 BR 112022016909A2 BR 112022016909 A BR112022016909 A BR 112022016909A BR 112022016909 A BR112022016909 A BR 112022016909A BR 112022016909 A2 BR112022016909 A2 BR 112022016909A2
Authority
BR
Brazil
Prior art keywords
methods
cells
cancer
treatment
cell expansion
Prior art date
Application number
BR112022016909A
Other languages
English (en)
Inventor
MATA Melinda
Kalra Mamta
Mohamed Ali
Walter Steffen
BULLIARD Yannick
Original Assignee
Immatics Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immatics Us Inc filed Critical Immatics Us Inc
Publication of BR112022016909A2 publication Critical patent/BR112022016909A2/pt

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
    • A61K2239/57—Skin; melanoma
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    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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Abstract

MÉTODOS PARA A EXPANSÃO DE CÉLULAS T PARA O TRATAMENTO DE CÂNCER E MALIGNIDADES ASSOCIADAS. Um método in vitro de expansão de células T ?d , o qual inclui isolar células T ?d de uma amostra de sangue de um sujeito humano, ativar as células T ?d isoladas na presença de um aminobifosfonato e/ou uma célula alimentadora e pelo menos uma citocina, expandir as células T ?d ativadas e, opcionalmente, reestimular as células T ?d expandidas.
BR112022016909A 2020-02-24 2021-02-23 Métodos para a expansão de células t para o tratamento de câncer e malignidades associadas BR112022016909A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202062980844P 2020-02-24 2020-02-24
US202063038008P 2020-06-11 2020-06-11
US202063082881P 2020-09-24 2020-09-24
PCT/US2021/019252 WO2021173560A1 (en) 2020-02-24 2021-02-23 Methods for expanding t cells for the treatment of cancer and related malignancies

Publications (1)

Publication Number Publication Date
BR112022016909A2 true BR112022016909A2 (pt) 2022-12-06

Family

ID=74875356

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022016909A BR112022016909A2 (pt) 2020-02-24 2021-02-23 Métodos para a expansão de células t para o tratamento de câncer e malignidades associadas

Country Status (11)

Country Link
EP (1) EP4110901A1 (pt)
JP (1) JP2023515131A (pt)
KR (1) KR20230012465A (pt)
CN (1) CN115427554A (pt)
AU (1) AU2021225817A1 (pt)
BR (1) BR112022016909A2 (pt)
CA (1) CA3168729A1 (pt)
IL (1) IL295891A (pt)
MX (1) MX2022010461A (pt)
TW (1) TW202146645A (pt)
WO (1) WO2021173560A1 (pt)

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Publication number Priority date Publication date Assignee Title
KR20230105166A (ko) * 2022-01-03 2023-07-11 주식회사 이뮤노맥스 감마-델타 t 세포의 증식 배양 방법
GB202204926D0 (en) * 2022-04-04 2022-05-18 Gammadelta Therapeutics Ltd Method for expanding gammadelta T cells

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