BR112013004436A2 - composições e usos de materiais com atividade microbicida alta e toxicidade baixa - Google Patents
composições e usos de materiais com atividade microbicida alta e toxicidade baixaInfo
- Publication number
- BR112013004436A2 BR112013004436A2 BR112013004436A BR112013004436A BR112013004436A2 BR 112013004436 A2 BR112013004436 A2 BR 112013004436A2 BR 112013004436 A BR112013004436 A BR 112013004436A BR 112013004436 A BR112013004436 A BR 112013004436A BR 112013004436 A2 BR112013004436 A2 BR 112013004436A2
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- materials
- low toxicity
- microbicidal activity
- high microbicidal
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3526—Organic compounds containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Dispersion Chemistry (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Microbiology (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Reproductive Health (AREA)
Abstract
composições e usos de materiais com atividade microbicida alta e toxicidade baixa. trata-se de copolipeptídeos sintéticos microbicidas aprimorados que contém resíduos de aminoácidos catiônico e podem ser baseados em uma sequência de bloco. esses microbicidas mostram toxicidade de mamífero baixa e podem sofrer automontagem direcionada. os copolipeptídeos sintéticos da invenção são utéis no tratamento de ferimentos e outras infecções.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37619510P | 2010-08-23 | 2010-08-23 | |
PCT/US2011/048869 WO2012027411A2 (en) | 2010-08-23 | 2011-08-23 | Compositions and uses of materials with high antimicrobial activity and low toxicity |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112013004436A2 true BR112013004436A2 (pt) | 2016-06-21 |
Family
ID=45724032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013004436A BR112013004436A2 (pt) | 2010-08-23 | 2011-08-23 | composições e usos de materiais com atividade microbicida alta e toxicidade baixa |
Country Status (16)
Country | Link |
---|---|
US (3) | US9017730B2 (pt) |
EP (1) | EP2608800B1 (pt) |
JP (1) | JP5902171B2 (pt) |
CN (1) | CN103260635A (pt) |
AU (3) | AU2011293468B2 (pt) |
BR (1) | BR112013004436A2 (pt) |
CA (2) | CA2809093C (pt) |
DK (1) | DK2608800T3 (pt) |
ES (1) | ES2622498T3 (pt) |
HU (1) | HUE032899T2 (pt) |
LT (1) | LT2608800T (pt) |
MX (1) | MX342039B (pt) |
PL (1) | PL2608800T3 (pt) |
PT (1) | PT2608800T (pt) |
SG (1) | SG188281A1 (pt) |
WO (1) | WO2012027411A2 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE032899T2 (hu) | 2010-08-23 | 2017-11-28 | Univ California | Nagy mikrobaellenes aktivitással és kis toxicitással rendelkezõ anyagok kompozíciói és alkalmazásai |
CA2867903C (en) * | 2012-03-23 | 2023-02-14 | Amicrobe, Inc. | Compositions and uses of antimicrobial materials with tissue-compatible properties |
DK3185882T3 (da) * | 2014-08-29 | 2020-01-27 | Region Midtjylland | Positivt ladede copolymerer til anvendelse som antimikrobielle midler |
WO2016054432A1 (en) | 2014-10-01 | 2016-04-07 | The Regents Of The University Of California | Non-ionic and thermoresponsive diblock copolypeptide hydrogels for delivery of molecules and cells |
CN106674329B (zh) * | 2015-11-05 | 2021-07-23 | 程家维 | 具备抗微生物、抗癌/促进伤口愈合活性的肽及其用途 |
CN105708592B (zh) * | 2016-04-17 | 2018-04-24 | 河南科技大学第一附属医院 | 一种手外科术后的手臂支架 |
AU2018249552A1 (en) | 2017-04-06 | 2019-10-31 | Amicrobe, Inc. | Compositions and uses of locally-applied antimicrobial synthetic cationic polypeptide(s) with enhanced performance and safety |
CN111234034B (zh) * | 2020-01-22 | 2021-10-08 | 国家纳米科学中心 | 一种调控细胞膜受体的多肽组合物及其制备方法和应用 |
AU2021252544A1 (en) * | 2020-04-08 | 2022-11-03 | Amicrobe, Inc. | Compositions and uses of locally applied synthetic amino acid polymers for prevention and treatment of viral infections |
US12090206B2 (en) | 2020-04-23 | 2024-09-17 | The Regents Of The University Of California | Compositions comprising tri- and penta-block synthetic copolypeptide hydrogels |
US20240350579A1 (en) * | 2020-08-10 | 2024-10-24 | Gel4Med, Inc. | Antifungal matrix formed from peptide hydrogels |
CN112933108B (zh) * | 2021-02-05 | 2024-07-23 | 华东理工大学 | 掺杂多肽聚合物的骨髓腔填充物及在骨髓炎治疗中的用途 |
CN114748681B (zh) * | 2022-04-13 | 2023-03-10 | 四川大学 | 一种可注射自愈合水凝胶敷料及其制备方法、用途 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5856308A (en) * | 1996-09-27 | 1999-01-05 | Haemacure Corporation | Artificial collagen |
US6686446B2 (en) | 1998-03-19 | 2004-02-03 | The Regents Of The University Of California | Methods and compositions for controlled polypeptide synthesis |
AU2001275409A1 (en) | 2000-06-08 | 2001-12-17 | The Regents Of The University Of California | Methods and compositions for controlled polypeptide synthesis |
US20050079159A1 (en) | 2001-06-13 | 2005-04-14 | Massachusetts Instiute Of Technology | In vivo bioreactors |
AU2002365135A1 (en) | 2001-10-23 | 2003-07-09 | Anteon Corporation | Integrated oxygen generation and carbon dioxide absorption method, apparatus and systems |
US20030147958A1 (en) * | 2002-01-29 | 2003-08-07 | Cheol-Hee Ahn | Biodegradable multi-block copolymers of poly(amino acid)s and poly(ethylene glycol) for the delivery of bioactive agents |
US7204997B2 (en) | 2002-01-29 | 2007-04-17 | Supratek Pharma Inc. | Responsive microgel and methods related thereto |
CA2519023C (en) * | 2003-03-17 | 2014-05-20 | The Trustees Of The University Of Pennsylvania | Facially amphiphilic polymers and oligomers and uses thereof |
US7329638B2 (en) | 2003-04-30 | 2008-02-12 | The Regents Of The University Of Michigan | Drug delivery compositions |
EP1644382B1 (en) * | 2003-07-11 | 2008-03-05 | Theravance, Inc. | Cross-linked glycopeptide-cephalosporin antibiotics |
EP1907444B1 (en) | 2005-04-01 | 2009-08-19 | Intezyne Technologies Incorporated | Polymeric micelles for drug delivery |
EP1868629B1 (en) | 2005-04-15 | 2014-10-22 | Arizona Biomedical Research Commission | Therapeutic fusion peptides for the treatment of metastatic cancer |
US9505867B2 (en) | 2005-05-31 | 2016-11-29 | Ecole Polytechmique Fédérale De Lausanne | Triblock copolymers for cytoplasmic delivery of gene-based drugs |
WO2007095005A1 (en) * | 2006-02-10 | 2007-08-23 | Z-Medica Corporation | Agents and devices for providing blood clotting functions to wounds |
US9168329B2 (en) * | 2006-09-01 | 2015-10-27 | Wisconsin Alumni Research Foundation | Beta-peptides with antifungal activity |
JP2010511630A (ja) * | 2006-12-01 | 2010-04-15 | ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア | 自己組織化ブロックコポリマーのベシクル、ならびにその生成および使用法 |
US20080311045A1 (en) | 2007-06-06 | 2008-12-18 | Biovaluation & Analysis, Inc. | Polymersomes for Use in Acoustically Mediated Intracellular Drug Delivery in vivo |
JP5143231B2 (ja) * | 2007-08-21 | 2013-02-13 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 共重合体安定化エマルション |
EP2400974B1 (en) | 2009-02-18 | 2017-09-06 | The Regents of the University of California | Synthetic diblock copolypeptide hydrogels for use in the central nervous system |
HUE032899T2 (hu) | 2010-08-23 | 2017-11-28 | Univ California | Nagy mikrobaellenes aktivitással és kis toxicitással rendelkezõ anyagok kompozíciói és alkalmazásai |
EP2961758A4 (en) | 2013-02-26 | 2016-10-19 | Univ California | AMPHIPHIL DERIVATIVES OF BLOCK COPOLYPEPTIDES WITH THIOETHERS |
-
2011
- 2011-08-23 HU HUE11820553A patent/HUE032899T2/hu unknown
- 2011-08-23 DK DK11820553.3T patent/DK2608800T3/da active
- 2011-08-23 ES ES11820553.3T patent/ES2622498T3/es active Active
- 2011-08-23 CA CA2809093A patent/CA2809093C/en active Active
- 2011-08-23 CN CN201180051224XA patent/CN103260635A/zh active Pending
- 2011-08-23 JP JP2013526108A patent/JP5902171B2/ja active Active
- 2011-08-23 LT LTEP11820553.3T patent/LT2608800T/lt unknown
- 2011-08-23 WO PCT/US2011/048869 patent/WO2012027411A2/en active Application Filing
- 2011-08-23 EP EP11820553.3A patent/EP2608800B1/en active Active
- 2011-08-23 CA CA2912577A patent/CA2912577C/en active Active
- 2011-08-23 PT PT118205533T patent/PT2608800T/pt unknown
- 2011-08-23 PL PL11820553T patent/PL2608800T3/pl unknown
- 2011-08-23 SG SG2013013602A patent/SG188281A1/en unknown
- 2011-08-23 MX MX2013002122A patent/MX342039B/es active IP Right Grant
- 2011-08-23 BR BR112013004436A patent/BR112013004436A2/pt not_active Application Discontinuation
- 2011-08-23 AU AU2011293468A patent/AU2011293468B2/en active Active
-
2013
- 2013-02-25 US US13/776,221 patent/US9017730B2/en active Active
-
2014
- 2014-08-13 AU AU2014213503A patent/AU2014213503B2/en active Active
-
2015
- 2015-04-22 US US14/693,601 patent/US10448634B2/en active Active
-
2016
- 2016-06-06 AU AU2016203767A patent/AU2016203767B2/en active Active
-
2019
- 2019-10-21 US US16/658,861 patent/US20200288709A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MX342039B (es) | 2016-09-09 |
AU2016203767B2 (en) | 2018-04-26 |
CA2912577C (en) | 2019-02-19 |
AU2011293468A1 (en) | 2013-03-14 |
US9017730B2 (en) | 2015-04-28 |
CA2809093C (en) | 2015-11-24 |
EP2608800A2 (en) | 2013-07-03 |
WO2012027411A2 (en) | 2012-03-01 |
PL2608800T3 (pl) | 2017-08-31 |
DK2608800T3 (da) | 2017-05-01 |
ES2622498T3 (es) | 2017-07-06 |
CA2912577A1 (en) | 2012-03-01 |
US10448634B2 (en) | 2019-10-22 |
US20200288709A1 (en) | 2020-09-17 |
CN103260635A (zh) | 2013-08-21 |
LT2608800T (lt) | 2017-05-10 |
WO2012027411A9 (en) | 2012-05-31 |
WO2012027411A3 (en) | 2012-07-19 |
US20130267458A1 (en) | 2013-10-10 |
AU2011293468B2 (en) | 2014-05-15 |
EP2608800B1 (en) | 2017-01-18 |
MX2013002122A (es) | 2013-06-05 |
PT2608800T (pt) | 2017-05-03 |
US20150366193A1 (en) | 2015-12-24 |
AU2016203767A1 (en) | 2016-06-23 |
SG188281A1 (en) | 2013-04-30 |
JP5902171B2 (ja) | 2016-04-13 |
CA2809093A1 (en) | 2012-03-01 |
HUE032899T2 (hu) | 2017-11-28 |
JP2013536242A (ja) | 2013-09-19 |
AU2014213503B2 (en) | 2016-03-10 |
AU2014213503A1 (en) | 2014-09-04 |
EP2608800A4 (en) | 2014-01-22 |
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