BR112012020731A2 - pastilhas gelatinosas suaves com nicotina. - Google Patents
pastilhas gelatinosas suaves com nicotina.Info
- Publication number
- BR112012020731A2 BR112012020731A2 BR112012020731A BR112012020731A BR112012020731A2 BR 112012020731 A2 BR112012020731 A2 BR 112012020731A2 BR 112012020731 A BR112012020731 A BR 112012020731A BR 112012020731 A BR112012020731 A BR 112012020731A BR 112012020731 A2 BR112012020731 A2 BR 112012020731A2
- Authority
- BR
- Brazil
- Prior art keywords
- nicotine
- soft gelatin
- gelatin tablets
- tablets
- soft
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title abstract 3
- 229960002715 nicotine Drugs 0.000 title abstract 3
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title abstract 3
- 108010010803 Gelatin Proteins 0.000 title abstract 2
- 229920000159 gelatin Polymers 0.000 title abstract 2
- 239000008273 gelatin Substances 0.000 title abstract 2
- 235000019322 gelatine Nutrition 0.000 title abstract 2
- 235000011852 gelatine desserts Nutrition 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 235000003599 food sweetener Nutrition 0.000 abstract 1
- 238000002670 nicotine replacement therapy Methods 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 239000003765 sweetening agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
pastilhas gelatinosas suaves com nicotina. é disponibilizada uma pastilha suave para terapia de substituição de nicotina. a pastilha compreende cerca de 0,05% a 1% de nicotina activo. a pastilha compreende cerca de 0,05% a 10% de adoçante; 0,05% a 30% de agente libertador; cerca de 0,05% a 2% de conservante; cerca de 0,01% a 5% de agente de saber; e cerca de 5% a 20% de água.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN452MU2010 | 2010-02-18 | ||
PCT/IN2010/000768 WO2011101860A1 (en) | 2010-02-18 | 2010-11-26 | Nicotine-containing soft gelatin pastilles |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112012020731A2 true BR112012020731A2 (pt) | 2016-04-26 |
Family
ID=43531759
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012020731A BR112012020731A2 (pt) | 2010-02-18 | 2010-11-26 | pastilhas gelatinosas suaves com nicotina. |
Country Status (19)
Country | Link |
---|---|
US (1) | US8470366B2 (pt) |
EP (1) | EP2536409A4 (pt) |
JP (1) | JP5845194B2 (pt) |
KR (1) | KR20130008535A (pt) |
CN (1) | CN102770138B (pt) |
AU (1) | AU2011100027A4 (pt) |
BR (1) | BR112012020731A2 (pt) |
CH (1) | CH702775B1 (pt) |
CL (1) | CL2012002115A1 (pt) |
CO (1) | CO6511280A2 (pt) |
CR (1) | CR20120400A (pt) |
DO (1) | DOP2012000217A (pt) |
EA (1) | EA018939B1 (pt) |
MX (1) | MX2012009586A (pt) |
MY (1) | MY153805A (pt) |
PH (1) | PH12012501487A1 (pt) |
UA (1) | UA107103C2 (pt) |
WO (1) | WO2011101860A1 (pt) |
ZA (1) | ZA201206597B (pt) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130078307A1 (en) * | 2011-09-22 | 2013-03-28 | Niconovum Usa, Inc. | Nicotine-containing pharmaceutical composition |
US9629392B2 (en) | 2011-09-22 | 2017-04-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
US9763928B2 (en) | 2012-02-10 | 2017-09-19 | Niconovum Usa, Inc. | Multi-layer nicotine-containing pharmaceutical composition |
JP2016524916A (ja) | 2013-07-19 | 2016-08-22 | アルトリア クライアント サービシーズ リミテッド ライアビリティ カンパニー | ニコチンをオーラル製品中に組み込むための方法およびシステム |
US20160184236A1 (en) * | 2013-08-08 | 2016-06-30 | Orahealth Corp. | Reducing reflux while sleeping by stimulating saliva with adhering troches |
US11779045B2 (en) | 2013-10-03 | 2023-10-10 | Altria Client Services Llc | Dissolvable-chewable exhausted-tobacco tablet |
US10244786B2 (en) | 2013-10-03 | 2019-04-02 | Altria Client Services Llc | Tobacco lozenge |
US9351936B2 (en) * | 2013-10-03 | 2016-05-31 | Altria Client Services Llc | Nicotine lozenge |
US10105320B2 (en) | 2013-10-03 | 2018-10-23 | Altria Client Services | Soluble fiber lozenge |
US9999243B2 (en) | 2013-10-03 | 2018-06-19 | Altria Client Services Llc | Exhausted tobacco lozenge |
IN2013MU01590A (pt) * | 2013-11-02 | 2015-08-07 | Jatin Vasant Thakkar | |
US9375033B2 (en) * | 2014-02-14 | 2016-06-28 | R.J. Reynolds Tobacco Company | Tobacco-containing gel composition |
EP3117826A4 (en) * | 2014-03-11 | 2017-09-13 | Farmalider, S.A. | Tobacco substitute product |
CA3031241A1 (en) * | 2016-07-29 | 2018-02-01 | Philip Morris Products S.A. | Aerosol-generating system comprising a heated gel container |
US10772355B2 (en) | 2016-07-29 | 2020-09-15 | Altria Client Services Llc | Aerosol-generating system including a heated gel container |
WO2023062109A1 (en) | 2021-10-13 | 2023-04-20 | Wm19 Holding Ag | Oral formulations comprising nicotine salt |
KR102714910B1 (ko) | 2022-10-07 | 2024-10-11 | 어보브반도체 주식회사 | 동기 정류식 직류-직류 컨버터 |
WO2024037043A1 (zh) * | 2023-04-28 | 2024-02-22 | 深圳华宝协同创新技术研究院有限公司 | 用于口腔粘膜的包含尼古丁的薄膜组合物 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US680734A (en) | 1900-09-13 | 1901-08-20 | N L Syndicate Ltd | Process of making waterproof fabric and product thereof. |
GB8615676D0 (en) | 1986-06-26 | 1986-07-30 | Stoppers Co Ltd | Nicotine containing lozenge |
GB2230439A (en) | 1989-04-20 | 1990-10-24 | Alec Stanley Walter Shaw | Nicotine lozenges |
DK615689A (da) * | 1989-11-07 | 1991-05-08 | Anders Dam | Rygesupplement eller rygeerstatningsprodukt |
US5525351A (en) * | 1989-11-07 | 1996-06-11 | Dam; Anders | Nicotine containing stimulant unit |
US5488962A (en) | 1990-10-10 | 1996-02-06 | Perfetti, S.P.A. | Chewing gum which is a substitute for tobacco smoke |
US5549906A (en) * | 1993-07-26 | 1996-08-27 | Pharmacia Ab | Nicotine lozenge and therapeutic method for smoking cessation |
GB2299756A (en) * | 1995-03-29 | 1996-10-16 | Gilbert Falkingham Clayton | Gelatinous pastille containing nicotine |
CZ298212B6 (cs) | 1996-05-13 | 2007-07-25 | Novartis Consumer Health S. A. | Pomalu se rozpadající pastilka |
US5928664A (en) * | 1998-02-11 | 1999-07-27 | Fuisz Technologies Ltd. | Consumable gummy delivery system |
US6344222B1 (en) | 1998-09-03 | 2002-02-05 | Jsr Llc | Medicated chewing gum delivery system for nicotine |
CA2440713A1 (en) * | 2001-03-26 | 2002-10-03 | Smithkline Beecham Corporation | Nicotine-containing oral dosage form |
US20030087937A1 (en) * | 2001-10-15 | 2003-05-08 | Nils-Olof Lindberg | Nicotine and cocoa powder compositions |
US20040151771A1 (en) | 2003-02-04 | 2004-08-05 | Gin Jerry B. | Long-lasting, flavored dosage forms for sustained release of beneficial agents within the mouth |
WO2004096184A1 (en) * | 2003-05-02 | 2004-11-11 | Warner-Lambert Company Llc | Confectionery products for delivery of pharmaceutically active agents to the throat |
US20050034738A1 (en) * | 2003-08-11 | 2005-02-17 | Whalen William F. | Chewing tobacco substitute containing nicotine |
ATE422355T1 (de) * | 2003-09-08 | 2009-02-15 | Mcneil Ab | Nikotinformulierungen und ihre verwendung |
US20050123502A1 (en) * | 2003-10-07 | 2005-06-09 | Chan Shing Y. | Nicotine containing oral compositions |
MX2008010703A (es) * | 2006-02-24 | 2008-09-01 | Lubrizol Advanced Mat Inc | Polimeros que contienen macromeros de copoliol de silicona y composiciones para el cuidado personal que los contienen. |
JP2009529561A (ja) * | 2006-03-16 | 2009-08-20 | ニコノヴァム エービー | ニコチンの速やかな放出をもたらす安定なロゼンジ組成物 |
US20070269492A1 (en) * | 2006-05-16 | 2007-11-22 | Per Steen | New product and use and manufacture thereof |
US20070269386A1 (en) | 2006-05-16 | 2007-11-22 | Per Steen | New product and use and manufacture thereof |
AR071420A1 (es) | 2008-05-01 | 2010-06-16 | Smithkline Beecham Corp | Composicion de pastilla para chupar oral que comprende un principio activo de nicotina y procedimiento para fabricarla |
-
2010
- 2010-11-26 CN CN201080064198.XA patent/CN102770138B/zh not_active Expired - Fee Related
- 2010-11-26 UA UAA201209968A patent/UA107103C2/uk unknown
- 2010-11-26 KR KR1020127021803A patent/KR20130008535A/ko not_active Application Discontinuation
- 2010-11-26 JP JP2012553443A patent/JP5845194B2/ja not_active Expired - Fee Related
- 2010-11-26 EP EP20100846028 patent/EP2536409A4/en not_active Withdrawn
- 2010-11-26 PH PH1/2012/501487A patent/PH12012501487A1/en unknown
- 2010-11-26 MX MX2012009586A patent/MX2012009586A/es not_active Application Discontinuation
- 2010-11-26 BR BR112012020731A patent/BR112012020731A2/pt not_active IP Right Cessation
- 2010-11-26 WO PCT/IN2010/000768 patent/WO2011101860A1/en active Application Filing
-
2011
- 2011-01-06 AU AU2011100027A patent/AU2011100027A4/en not_active Ceased
- 2011-02-07 EA EA201100153A patent/EA018939B1/ru not_active IP Right Cessation
- 2011-02-08 CH CH00229/11A patent/CH702775B1/fr not_active IP Right Cessation
- 2011-02-17 US US13/029,163 patent/US8470366B2/en active Active
- 2011-02-18 MY MYPI2011000742A patent/MY153805A/en unknown
-
2012
- 2012-07-27 CR CR20120400A patent/CR20120400A/es unknown
- 2012-07-31 CL CL2012002115A patent/CL2012002115A1/es unknown
- 2012-08-06 DO DO2012000217A patent/DOP2012000217A/es unknown
- 2012-08-08 CO CO12132681A patent/CO6511280A2/es not_active Application Discontinuation
- 2012-08-30 ZA ZA2012/06597A patent/ZA201206597B/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP5845194B2 (ja) | 2016-01-20 |
KR20130008535A (ko) | 2013-01-22 |
JP2013520408A (ja) | 2013-06-06 |
PH12012501487A1 (en) | 2016-07-27 |
AU2011100027A4 (en) | 2011-02-03 |
EA201100153A1 (ru) | 2011-08-30 |
CN102770138A (zh) | 2012-11-07 |
DOP2012000217A (es) | 2013-03-15 |
EP2536409A1 (en) | 2012-12-26 |
UA107103C2 (uk) | 2014-11-25 |
MY153805A (en) | 2015-03-31 |
US8470366B2 (en) | 2013-06-25 |
US20110200670A1 (en) | 2011-08-18 |
CN102770138B (zh) | 2015-12-09 |
CR20120400A (es) | 2012-10-23 |
EP2536409A4 (en) | 2013-07-17 |
CL2012002115A1 (es) | 2013-05-24 |
CO6511280A2 (es) | 2012-08-31 |
EA018939B1 (ru) | 2013-11-29 |
CH702775B1 (fr) | 2011-08-15 |
ZA201206597B (en) | 2013-05-29 |
MX2012009586A (es) | 2012-09-12 |
WO2011101860A1 (en) | 2011-08-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112012020731A2 (pt) | pastilhas gelatinosas suaves com nicotina. | |
ES2557303T3 (es) | Agente terapéutico para la estenosis del canal espinal | |
CY1124135T1 (el) | Δοσολογικα σχηματα για την αγωγη της νοσου ρομρε | |
CL2012002317A1 (es) | Compuestos derivados de tienopirimidinas, inhibitores de quinasas mnk1/mnk2; composicion farmaceutica; y su uso para elt ratamiento o profilaxis de enfermedades metabolicas, tales como diabetes, daño renal, cancer, enfermedades inflamatorias, entre otras. | |
CR20120345A (es) | Derivados de 3-hidroxi-5-arilisotiazol novedosos | |
BR112012023021A2 (pt) | compostos de indazol e seus usos | |
EA201170876A1 (ru) | Применение способной к вспениванию композиции, по существу, не содержащей фармацевтически активные ингредиенты, для лечения кожи человека | |
AR092661A1 (es) | Inhibidor de quinasas reordenadas durante la transfeccion (ret) y un metodo para identificar un paciente sensible a un compuesto representado por la formula (1) | |
PE20142314A1 (es) | Composiciones intranasales de dexmedetomidina y metodos de uso de ellas | |
PE20140255A1 (es) | Tableta dispersable en forma oral | |
CR20140005A (es) | Una nueva composición terapéutica que contiene apomorfina como principio activo | |
CO6460753A2 (es) | Procedimiento y composición para mejorar la absorción de agentes terapéuticos | |
EA201201202A1 (ru) | Пероральная фармацевтическая композиция, содержащая этексилат дабигатрана | |
BR112014020271A8 (pt) | Composição farmacêutica e métodos para diminuir a frequência de micção em paciente | |
MX349854B (es) | Composiciones antitranspirantes y metodo para reducir la transpiracion. | |
EA201071209A1 (ru) | Применение дронедарона или его фармацевтически приемлемой соли для получения лекарственного средства для регуляции уровня калия в крови | |
AR080096A1 (es) | Tratamiento combinado de cancer de pancreas con gemcitabina y masitinib | |
PE20061390A1 (es) | Formulaciones de acido hidroxamico suberoilanilida y procedimientos para la produccion de las mismas | |
CL2016002318A1 (es) | Composición farmacéutica en forma de solución que comprende un portador líquido que comprende agua y entre 20% y 95% de uno o mas alcoholes y citrato de sildenafil disuelto en dicho portador líquido a una concentración de entre 7 y 125 mg/ml; métodos para obtenerla; forma de dosificación oral; forma de dosificación bucal; kits. | |
CL2011001829A1 (es) | 3'-n-desmetil-4''-o-(2-dietilaminoetanoil)-6-o-metil-9a-aza-9a-homoeritromicina a, sus sales y formas cristalinas 1, 2 y 3; proceso de preparacion; uso para tratar enfermedades inflamatorias; composicion farmaceutica; y composicion que ademas comprende otro compuesto activo. | |
GEP20156410B (en) | Formulation comprising phenylaminopyrimidine derivative as active agent | |
ES2723778T3 (es) | Terapia dirigida a células madre cancerosas y contra cáncer resistente a fármacos | |
AR098832A1 (es) | Uso de laquinimod para retrasar la progresión de la enfermedad de huntington | |
CL2007002363A1 (es) | Procedo para retrasar o prevenir la cristalizacion de un material que comprende crear gotitas encapsuladas de una solucion de un material activo que es sustancialmente insoluble en condiciones acuosas, donde el agente encapsulante es una pelicula for | |
UA109944U (uk) | Фармацевтична композиція для зниження рівня n-оксиду триметиламіну |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2386 DE 27-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |