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BR112012012603A2 - pós-carregamento de materiais plásticos impregnados de zeólitos com íons metálicos antimicrobianos - Google Patents

pós-carregamento de materiais plásticos impregnados de zeólitos com íons metálicos antimicrobianos

Info

Publication number
BR112012012603A2
BR112012012603A2 BR112012012603A BR112012012603A BR112012012603A2 BR 112012012603 A2 BR112012012603 A2 BR 112012012603A2 BR 112012012603 A BR112012012603 A BR 112012012603A BR 112012012603 A BR112012012603 A BR 112012012603A BR 112012012603 A2 BR112012012603 A2 BR 112012012603A2
Authority
BR
Brazil
Prior art keywords
certain embodiments
zeolite
antimicrobial metal
afterloading
metal ions
Prior art date
Application number
BR112012012603A
Other languages
English (en)
Other versions
BR112012012603B1 (pt
Inventor
Johns Derrick
J Crudden Joseph
Original Assignee
Difusion Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44067221&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112012012603(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Difusion Tech Inc filed Critical Difusion Tech Inc
Publication of BR112012012603A2 publication Critical patent/BR112012012603A2/pt
Publication of BR112012012603B1 publication Critical patent/BR112012012603B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/443—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with carbon fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/21—Pharmaceuticals, e.g. medicaments, artificial body parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A61L2300/104—Silver, e.g. silver sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Molecular Biology (AREA)
  • Ceramic Engineering (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Prostheses (AREA)
  • Polymers & Plastics (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Dental Preparations (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

pós-carregamento de materiais plásticos impregnados de zeólitos com íons metálicos antimicrobianos. método de pós-carregamento de partículas de cerâmica com cátions metálicos antimicrobianos são divulgados. em determinadas modalidades, as partículas pós-carregadas são zeólitos, em que os zeólitos foram incorporados em uma resina e a combinação é usada como um dispositivo implantável. em determinadas modalidades, o polímero é um polímero termoplástico, tal como poliarileteretercetona (peek). em determinadas modalidades, a fonte de atividade antimicrobiana inclui cátions de troca iônica contidos em um zeólito. em determinadas modalidades, são dilvulgados métodos para conferir atividade antimocrobiana a dispositivos pelo controle da entrega de determinados cátions por meio de troca iônica através de um zeólito incorporado no dispositivo.
BR112012012603-2A 2009-11-25 2010-11-24 Método de pós-carregamento de partículas de cerâmica com cátions metálicos antimicrobianos e método de conferir atividade antimicrobiana a um dispositivo através do controle da liberação de cátions antimicrobianos a partir do referido dispositivo por meio de troca iônica BR112012012603B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US26428909P 2009-11-25 2009-11-25
US61/264,289 2009-11-25
US30063110P 2010-02-02 2010-02-02
US61/300,631 2010-02-02
PCT/US2010/058009 WO2011066391A2 (en) 2009-11-25 2010-11-24 Post-charging of zeolite doped plastics with antimicrobial metal ions

Publications (2)

Publication Number Publication Date
BR112012012603A2 true BR112012012603A2 (pt) 2017-11-21
BR112012012603B1 BR112012012603B1 (pt) 2019-03-19

Family

ID=44067221

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012012603-2A BR112012012603B1 (pt) 2009-11-25 2010-11-24 Método de pós-carregamento de partículas de cerâmica com cátions metálicos antimicrobianos e método de conferir atividade antimicrobiana a um dispositivo através do controle da liberação de cátions antimicrobianos a partir do referido dispositivo por meio de troca iônica

Country Status (7)

Country Link
US (4) US9492584B2 (pt)
EP (1) EP2504041B1 (pt)
CN (2) CN104941004B (pt)
BR (1) BR112012012603B1 (pt)
IN (1) IN2012DN04965A (pt)
RU (1) RU2552939C2 (pt)
WO (1) WO2011066391A2 (pt)

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WO2014152653A1 (en) * 2013-03-14 2014-09-25 Difusion Technologies, Inc. Self sterilizing orthopedic implants
WO2014152649A1 (en) * 2013-03-15 2014-09-25 Difusion Technologies, Inc. Enhanced efficacy self-sterilizing orthopedic implants
JP7379157B2 (ja) * 2017-02-09 2023-11-14 フェマシス インコーポレイテッド 生分解性シアノアクリレートを含む方法および組成物
US10918497B1 (en) 2017-10-24 2021-02-16 Omnia Medical, LLC Multi-material multi-component spinal implant
US11766339B1 (en) 2017-10-24 2023-09-26 Omnia Medical, LLC Multi-material multi-component spinal implant
US20210046218A1 (en) * 2018-02-02 2021-02-18 Evonik Operations Gmbh Functionally graded polymer knee implant for enhanced fixation, wear resistance, and mechanical properties and the fabrication thereof
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US11439726B2 (en) 2018-12-03 2022-09-13 Osseomimetic, LLC Surgical implants
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WO2023200847A1 (en) * 2022-04-14 2023-10-19 Difusion, Inc. Surgical implants with enhanced osseointegration and methods of manufacture

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US20120315340A1 (en) 2012-12-13
CN104941004A (zh) 2015-09-30
EP2504041A2 (en) 2012-10-03
US9492584B2 (en) 2016-11-15
US20200338238A1 (en) 2020-10-29
EP2504041B1 (en) 2017-04-12
US20200338237A1 (en) 2020-10-29
RU2552939C2 (ru) 2015-06-10
CN102802685B (zh) 2015-05-27
US20170021061A1 (en) 2017-01-26
CN102802685A (zh) 2012-11-28
IN2012DN04965A (pt) 2015-09-25
WO2011066391A3 (en) 2011-10-06
RU2012126078A (ru) 2013-12-27
CN104941004B (zh) 2018-09-14
BR112012012603B1 (pt) 2019-03-19

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