BR112016000968A2 - Processo para a preparação de bifenilanilidas halogenadas - Google Patents
Processo para a preparação de bifenilanilidas halogenadasInfo
- Publication number
- BR112016000968A2 BR112016000968A2 BR112016000968A BR112016000968A BR112016000968A2 BR 112016000968 A2 BR112016000968 A2 BR 112016000968A2 BR 112016000968 A BR112016000968 A BR 112016000968A BR 112016000968 A BR112016000968 A BR 112016000968A BR 112016000968 A2 BR112016000968 A2 BR 112016000968A2
- Authority
- BR
- Brazil
- Prior art keywords
- preparation
- biphenylanilides
- formula
- halogenated
- compound
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 1
- JVRMUFJCFLXSMJ-UHFFFAOYSA-N n,2-diphenylbenzamide Chemical class C=1C=CC=C(C=2C=CC=CC=2)C=1C(=O)NC1=CC=CC=C1 JVRMUFJCFLXSMJ-UHFFFAOYSA-N 0.000 abstract 1
- 150000002940 palladium Chemical class 0.000 abstract 1
- 229910000073 phosphorus hydride Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
- C07B37/04—Substitution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/66—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5004—Acyclic saturated phosphines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5022—Aromatic phosphines (P-C aromatic linkage)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5442—Aromatic phosphonium compounds (P-C aromatic linkage)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
Abstract
PROCESSO PARA A PREPARAÇÃO DE BIFENILANILIDAS HALOGENADAS. A presente invenção refere-se a um processo para a preparação de bifenilanilidas substituídas de fórmula (I) em que R(1) é selecionado a partir de um grupo amino protegido, NO(2), NH(2) e NHR(3), em que um composto da fórmula II é feito reagir na presença de uma base e de um sal de paládio, na presença de um ligante de fosfina da fórmula (V) como ligante complexo ou um sal do mesmo, em um solvente, com um composto de organoboro da fórmula (III) em que todos os substituintes são como definidos no relatório descritivo.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13177583 | 2013-07-23 | ||
| EP13177583.5 | 2013-07-23 | ||
| PCT/EP2014/065463 WO2015011032A1 (de) | 2013-07-23 | 2014-07-18 | Verbessertes verfahren zur herstellung von chlorierten biphenylaniliden und biphenylanilinen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112016000968A2 true BR112016000968A2 (pt) | 2017-08-29 |
| BR112016000968B1 BR112016000968B1 (pt) | 2021-05-18 |
Family
ID=48808249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112016000968-1A BR112016000968B1 (pt) | 2013-07-23 | 2014-07-18 | processo para a preparação de bifenilanilidas halogenadas |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9868694B2 (pt) |
| EP (2) | EP3024836B1 (pt) |
| JP (2) | JP6518242B2 (pt) |
| KR (1) | KR102310474B1 (pt) |
| CN (1) | CN105392791B (pt) |
| BR (1) | BR112016000968B1 (pt) |
| DK (1) | DK3024836T3 (pt) |
| ES (1) | ES2687950T3 (pt) |
| IL (1) | IL243680B (pt) |
| MX (1) | MX2016000621A (pt) |
| TW (1) | TWI658031B (pt) |
| WO (1) | WO2015011032A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2019002204A (es) * | 2016-08-22 | 2019-09-19 | Basf Se | Proceso para preparar bifenilos sustituidos. |
| ES2880323T3 (es) | 2017-02-14 | 2021-11-24 | Basf Se | Proceso para la preparación de bifenilos sustituidos |
| FR3064496A1 (fr) | 2017-03-31 | 2018-10-05 | Centre National De La Recherche Scientifique | Utilisation de materiaux naturels d'origine vegetale riches en acides phenoliques pour la mise en oeuvre de reaction de chimie organique et le recyclage de catalyseurs |
| CN107556199A (zh) * | 2017-09-24 | 2018-01-09 | 杨子辉 | 一种3,4‑二氯‑2‑氨基‑5‑氟联苯的制备方法 |
| DE102018122708A1 (de) * | 2018-09-17 | 2020-03-19 | Novaled Gmbh | Organische elektronische Vorrichtung, organisches halbleitendes Material und eine Boranverbindung |
| CN112955586B (zh) | 2018-10-29 | 2024-10-29 | C2Cnt有限责任公司 | 持续的、容易分离的熔融碳酸盐电解阴极产物 |
| AR119417A1 (es) | 2019-07-19 | 2021-12-15 | Adama Makhteshim Ltd | Proceso para la preparación de bifenilaminas |
| US20220042193A1 (en) | 2020-08-06 | 2022-02-10 | C2Cnt Llc | Sustainable, facile separation of the molten carbonate electrolysis cathode product |
| CN117321029A (zh) | 2021-05-19 | 2023-12-29 | 巴斯夫欧洲公司 | 经由芳基氯化物的Suzuki偶联制备取代联苯类的方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0888261B1 (de) | 1996-03-13 | 2001-11-28 | Basf Aktiengesellschaft | Verfahren zur herstellung von nitrobiphenylen |
| JP2001511813A (ja) * | 1997-02-18 | 2001-08-14 | ニューロクライン バイオサイエンシーズ，インコーポレイテッド | Ｃｒｆレセプターアンタゴニストおよびそれらに関連する方法 |
| US6307087B1 (en) * | 1998-07-10 | 2001-10-23 | Massachusetts Institute Of Technology | Ligands for metals and improved metal-catalyzed processes based thereon |
| FR2801884A1 (fr) | 1999-12-06 | 2001-06-08 | Rhodia Chimie Sa | Procede de preparation d'un compose polyaromatique |
| WO2003066643A1 (fr) * | 2002-02-04 | 2003-08-14 | Hokko Chemical Industry Co., Ltd. | Procede de production de phosphine tertiaire a groupe hydrocarbone volumineux lie |
| DE10215292A1 (de) | 2002-02-19 | 2003-08-28 | Bayer Cropscience Ag | Disubstitutierte Pyrazolylcarbocanilide |
| DE10252273A1 (de) * | 2002-11-11 | 2004-05-27 | Bayer Ag | Polyhalogenalkylaryle |
| WO2004052939A2 (en) * | 2002-12-09 | 2004-06-24 | Massachusetts Institute Of Technology | Ligands for metals and improved metal-catalyzed processes based thereon |
| CN100548948C (zh) * | 2002-12-09 | 2009-10-14 | 麻省理工学院 | 金属配体以及以此为基础的改良的金属催化方法 |
| CN1886411B (zh) * | 2003-11-28 | 2010-09-08 | 北兴化学工业株式会社 | 硼酸磷酯化合物的制造方法,新型硼酸磷酯化合物及其使用方法 |
| AR052930A1 (es) * | 2005-03-02 | 2007-04-11 | Basf Ag | Procedimiento para la preparacion de bifenilos sustituidos |
| DE102005022362B4 (de) * | 2005-05-10 | 2016-12-15 | Studiengesellschaft Kohle Mbh | Verfahren zur decarboxylierenden C-C Verknüpfung von Carbonsäuren mit Kohlenstoffelektrophilen |
| CN101374799B (zh) * | 2006-06-01 | 2012-05-23 | 巴斯夫欧洲公司 | 制备取代联苯的方法 |
| CA2636695A1 (en) | 2006-06-01 | 2007-12-06 | Basf Se | Process for preparing substituted biphenyls |
| EP2008991A1 (de) | 2007-06-29 | 2008-12-31 | Bayer CropScience AG | Verfahren zur Herstellung von Biarylen |
| EP2119697A1 (en) | 2008-05-09 | 2009-11-18 | Bayer CropScience AG | Process for preparing substituted biphenylanilides |
| ES2534557T3 (es) * | 2009-08-31 | 2015-04-24 | Bayer Intellectual Property Gmbh | Procedimiento de tetraarilborato para la preparación de bifenilos sustituidos |
| JP2013525448A (ja) * | 2010-04-27 | 2013-06-20 | カルシメディカ，インク． | 細胞内カルシウムを調節する化合物 |
-
2014
- 2014-07-18 ES ES14741287.8T patent/ES2687950T3/es active Active
- 2014-07-18 KR KR1020167001793A patent/KR102310474B1/ko active IP Right Grant
- 2014-07-18 BR BR112016000968-1A patent/BR112016000968B1/pt active IP Right Grant
- 2014-07-18 MX MX2016000621A patent/MX2016000621A/es active IP Right Grant
- 2014-07-18 JP JP2016528452A patent/JP6518242B2/ja active Active
- 2014-07-18 CN CN201480041369.5A patent/CN105392791B/zh active Active
- 2014-07-18 WO PCT/EP2014/065463 patent/WO2015011032A1/de active Application Filing
- 2014-07-18 DK DK14741287.8T patent/DK3024836T3/en active
- 2014-07-18 US US14/906,809 patent/US9868694B2/en active Active
- 2014-07-18 EP EP14741287.8A patent/EP3024836B1/de active Active
- 2014-07-18 EP EP18182552.2A patent/EP3418284A1/de not_active Withdrawn
- 2014-07-21 TW TW103124869A patent/TWI658031B/zh active
-
2016
- 2016-01-19 IL IL243680A patent/IL243680B/en active IP Right Grant
-
2017
- 2017-12-07 US US15/834,719 patent/US20180093942A1/en not_active Abandoned
-
2019
- 2019-02-26 JP JP2019033062A patent/JP2019108352A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL243680A0 (en) | 2016-04-21 |
| KR102310474B1 (ko) | 2021-10-07 |
| WO2015011032A1 (de) | 2015-01-29 |
| EP3024836A1 (de) | 2016-06-01 |
| CN105392791B (zh) | 2019-02-22 |
| US9868694B2 (en) | 2018-01-16 |
| IL243680B (en) | 2020-06-30 |
| TW201546031A (zh) | 2015-12-16 |
| EP3418284A1 (de) | 2018-12-26 |
| JP2019108352A (ja) | 2019-07-04 |
| US20180093942A1 (en) | 2018-04-05 |
| JP2016525526A (ja) | 2016-08-25 |
| CN105392791A (zh) | 2016-03-09 |
| EP3024836B1 (de) | 2018-07-11 |
| US20160280635A1 (en) | 2016-09-29 |
| TWI658031B (zh) | 2019-05-01 |
| ES2687950T3 (es) | 2018-10-30 |
| KR20160033702A (ko) | 2016-03-28 |
| BR112016000968B1 (pt) | 2021-05-18 |
| JP6518242B2 (ja) | 2019-05-22 |
| DK3024836T3 (en) | 2018-10-08 |
| MX2016000621A (es) | 2016-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/07/2014, OBSERVADAS AS CONDICOES LEGAIS. |