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BR112014029801A2 - composições e métodos de reconstrução óssea biofotônica - Google Patents

composições e métodos de reconstrução óssea biofotônica

Info

Publication number
BR112014029801A2
BR112014029801A2 BR112014029801A BR112014029801A BR112014029801A2 BR 112014029801 A2 BR112014029801 A2 BR 112014029801A2 BR 112014029801 A BR112014029801 A BR 112014029801A BR 112014029801 A BR112014029801 A BR 112014029801A BR 112014029801 A2 BR112014029801 A2 BR 112014029801A2
Authority
BR
Brazil
Prior art keywords
biophotonic
methods
compositions
bone reconstruction
photoactivator
Prior art date
Application number
BR112014029801A
Other languages
English (en)
Inventor
Loupis Nikolaos
Piergallini Remigio
Original Assignee
Klox Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Klox Tech Inc filed Critical Klox Tech Inc
Publication of BR112014029801A2 publication Critical patent/BR112014029801A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/884—Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
    • A61K6/898—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0084—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing fillers of phosphorus-containing inorganic compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/32—Phosphorus-containing compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
    • C08K5/0041—Optical brightening agents, organic pigments
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/15—Heterocyclic compounds having oxygen in the ring
    • C08K5/151—Heterocyclic compounds having oxygen in the ring having one oxygen atom in the ring
    • C08K5/1545—Six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
    • A61K6/838—Phosphorus compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/442—Colorants, dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A61N2005/0663—Coloured light
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/32—Phosphorus-containing compounds
    • C08K2003/321—Phosphates
    • C08K2003/325—Calcium, strontium or barium phosphate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Composite Materials (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

resumo "composições e métodos de reconstrução óssea biofotônica". a presente invenção refere-se a composições biofotônicas que compreendem um fotoativador, um mineral de fosfato de cálcio, ácido hialurônico e, opcionalmente, glucosamina. a dita composição tem utilidade no aumento, reparação e/ou regeneração do osso, quando usada em conjunto com luz actínica de um comprimento de onda absorvido pelo fotoativador.
BR112014029801A 2012-05-30 2013-05-30 composições e métodos de reconstrução óssea biofotônica BR112014029801A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261653101P 2012-05-30 2012-05-30
US201361777894P 2013-03-12 2013-03-12
PCT/CA2013/000532 WO2013177686A1 (en) 2012-05-30 2013-05-30 Compositions and methods for biophotonic bone reconstruction

Publications (1)

Publication Number Publication Date
BR112014029801A2 true BR112014029801A2 (pt) 2017-06-27

Family

ID=49672237

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014029801A BR112014029801A2 (pt) 2012-05-30 2013-05-30 composições e métodos de reconstrução óssea biofotônica

Country Status (17)

Country Link
US (1) US11426463B2 (pt)
EP (1) EP2854853B1 (pt)
JP (1) JP2015519134A (pt)
KR (1) KR20150023294A (pt)
CN (1) CN104394888A (pt)
AU (1) AU2013270353A1 (pt)
BR (1) BR112014029801A2 (pt)
CA (1) CA2873068A1 (pt)
HK (1) HK1207300A1 (pt)
IL (1) IL235687A0 (pt)
IN (1) IN2014DN09950A (pt)
MX (1) MX2014014458A (pt)
NZ (1) NZ701667A (pt)
RU (1) RU2014147975A (pt)
SG (1) SG11201407276RA (pt)
WO (1) WO2013177686A1 (pt)
ZA (1) ZA201408483B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9834740B2 (en) * 2014-01-24 2017-12-05 The Procter & Gamble Company Photoactivators
MX2016012933A (es) * 2014-04-01 2016-12-07 Klox Tech Inc Composiciones de relleno de tejidos y metodos de uso.
JP6158885B2 (ja) * 2015-10-14 2017-07-05 三菱電機株式会社 光源ユニット及び照明装置
KR102482319B1 (ko) 2020-09-29 2022-12-29 주식회사 시지바이오 고탄성의 인산 칼슘계 주입형 골 이식재 조성물 및 이의 제조방법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1259090B (it) * 1992-04-17 1996-03-11 Fidia Spa Biomaterialli per protesi d'osso
GB9721585D0 (en) 1997-10-10 1997-12-10 Geistlich Soehne Ag Chemical product
DE60020526T2 (de) * 1999-02-04 2006-05-11 SDGI Holdings, Inc., Wilmington Osteogene pastenzusammensetzungen und ihre verwendung
CN1172681C (zh) * 1999-08-18 2004-10-27 凌沛学 透明质酸口服美肤保健品
US8876532B2 (en) * 2002-07-31 2014-11-04 Dentsply International Inc. Bone repair putty
JP5449638B2 (ja) 2002-07-31 2014-03-19 デンツプライ インターナショナル インコーポレーテッド 多孔性粒子およびキャリアゲルを含む骨修復パテ
CA2505520C (en) 2002-11-06 2012-07-17 Azaya Therapeutics, Inc. Protein-stabilized liposomal formulations of pharmaceutical agents
EP1677664B1 (en) 2003-09-23 2014-07-30 Orthocon Inc. Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
ITPD20030286A1 (it) * 2003-11-27 2005-05-28 Fidia Advanced Biopolymers Srl Strutture composite multistrato contenenti acido ialuronico
EP1924160A2 (en) 2005-09-02 2008-05-28 Campina Nederland Holding B.V. Oral composition for moisturising skin
US9132208B2 (en) * 2008-08-07 2015-09-15 Lifenet Health Composition for a tissue repair implant and methods of making the same
WO2007079053A2 (en) * 2005-12-28 2007-07-12 Dentsply International Inc. Light-curable bone growth material for treating dental bone defects
US8999933B2 (en) 2006-01-18 2015-04-07 Biolitec Pharma Marketing Ltd Photodynamic cosmetic procedure and healing method
JP2007197371A (ja) 2006-01-26 2007-08-09 Yaizu Suisankagaku Industry Co Ltd 美肌促進剤及び美容健康食品
EP2114474A4 (en) 2006-12-08 2013-07-31 Graftoss Ltd MEDICAL PREPARATION
US8784893B2 (en) * 2007-02-05 2014-07-22 Carbylan Therapeutics, Inc. Polymer formulations for delivery of bioactive agents
EP2173296A1 (en) 2007-08-01 2010-04-14 The Johns Hopkins University Photoinitiated tissue filler
CA2721608A1 (en) * 2008-04-15 2009-10-22 Etex Corporation Minimally invasive treatment of vertebra (mitv) using a calcium phosphate combination bone cement
SI2453922T1 (en) * 2009-07-17 2018-04-30 Klox Technologies Inc. An antibacterial oral composition

Also Published As

Publication number Publication date
NZ701667A (en) 2017-05-26
US11426463B2 (en) 2022-08-30
HK1207300A1 (en) 2016-01-29
ZA201408483B (en) 2015-12-23
EP2854853A1 (en) 2015-04-08
AU2013270353A1 (en) 2014-11-27
SG11201407276RA (en) 2015-03-30
RU2014147975A (ru) 2016-07-20
CA2873068A1 (en) 2013-12-05
CN104394888A (zh) 2015-03-04
IN2014DN09950A (pt) 2015-08-14
WO2013177686A1 (en) 2013-12-05
KR20150023294A (ko) 2015-03-05
EP2854853A4 (en) 2016-01-13
IL235687A0 (en) 2015-01-29
MX2014014458A (es) 2015-08-14
EP2854853B1 (en) 2019-08-21
US20150119789A1 (en) 2015-04-30
JP2015519134A (ja) 2015-07-09

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