BR112014008196A2 - processo para a preparação de um composto - Google Patents

processo para a preparação de um composto

Info

Publication number: BR112014008196A2
Authority: BR; Brazil
Prior art keywords: compound; preparation
Prior art date: 2011-10-07

Application number

BR112014008196A

Other languages

English (en)

Other versions

BR112014008196B1 (pt

BR112014008196B8 (pt

Inventor

Pascal Jean-Claude

Original Assignee

Estetra Sprl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-10-07

Filing date

2012-10-05

Publication date

2017-04-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48043195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014008196(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2012-10-05 Application filed by Estetra Sprl filed Critical Estetra Sprl

2017-04-18 Publication of BR112014008196A2 publication Critical patent/BR112014008196A2/pt

2020-10-20 Publication of BR112014008196B1 publication Critical patent/BR112014008196B1/pt

2020-12-15 Publication of BR112014008196B8 publication Critical patent/BR112014008196B8/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BR112014008196A 2011-10-07 2012-10-05 processo para a preparação de um composto da fórmula (i) BR112014008196B8 (pt)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US201161544591P	2011-10-07	2011-10-07
EP11184278.7		2011-10-07
US61/544,591		2011-10-07
EP11184278		2011-10-07
PCT/EP2012/069761 WO2013050553A1 (en)	2011-10-07	2012-10-05	Process for the production of estetrol

Publications (3)

Publication Number	Publication Date
BR112014008196A2 true BR112014008196A2 (pt)	2017-04-18
BR112014008196B1 BR112014008196B1 (pt)	2020-10-20
BR112014008196B8 BR112014008196B8 (pt)	2020-12-15

Family

ID=48043195

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR112014008196A BR112014008196B8 (pt)	2011-10-07	2012-10-05	processo para a preparação de um composto da fórmula (i)

Country Status (27)

Country	Link
US (1)	US8987484B2 (pt)
EP (1)	EP2764008B1 (pt)
JP (1)	JP6196625B2 (pt)
KR (1)	KR102007874B1 (pt)
CN (1)	CN103890001B (pt)
AU (1)	AU2012320423C1 (pt)
BR (1)	BR112014008196B8 (pt)
CA (1)	CA2847813C (pt)
CL (1)	CL2014000802A1 (pt)
CY (1)	CY1118674T1 (pt)
DK (1)	DK2764008T3 (pt)
EA (1)	EA024003B1 (pt)
ES (1)	ES2593316T3 (pt)
HK (1)	HK1199882A1 (pt)
HR (1)	HRP20161282T1 (pt)
HU (1)	HUE028963T2 (pt)
IN (1)	IN2014MN00841A (pt)
LT (1)	LT2764008T (pt)
ME (1)	ME02527B (pt)
MX (1)	MX348917B (pt)
PL (1)	PL2764008T3 (pt)
PT (1)	PT2764008T (pt)
RS (1)	RS55231B1 (pt)
SG (1)	SG11201401282PA (pt)
SI (1)	SI2764008T1 (pt)
SM (1)	SMT201600375B (pt)
WO (1)	WO2013050553A1 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2012164095A1 (en)	2011-06-01	2012-12-06	Estetra S.A.	Process for the production of estetrol intermediates
DK2714710T3 (en)	2011-06-01	2016-06-27	Estetra Sprl	A process for the preparation of intermediates estetrol
EP2383279A1 (en)	2011-07-19	2011-11-02	Pantarhei Bioscience B.V.	Process for the preparation of estetrol
WO2013034780A2 (en) *	2012-12-20	2013-03-14	Crystal Pharma, S.A.U.	Process for the preparation of estetrol and related compounds
JP6254289B2 (ja) *	2013-09-18	2017-12-27	クリスタルファルマ、エセ、ア、ウＣｒｙｓｔａｌＰｈａｒｍａ，Ｓ．Ａ．Ｕ．	エステトロールの製造プロセス
SI3310346T1 (sl)	2015-06-18	2021-07-30	Estetra Sprl	Orodisperzibilna tableta, ki vsebuje estetrol
SI3701944T1 (sl)	2015-06-18	2022-04-29	Estetra Srl	Orodisperzibilna odmerna enota, ki vsebuje estetrolno komponento
PE20180398A1 (es)	2015-06-18	2018-02-28	Mithra Pharmaceuticals S A	Unidad de dosificacion orodispersable que contiene un componente estetrol
MA44205B1 (fr)	2015-06-18	2021-04-30	Estetra Sprl	Comprimé orodispersible comprenant estetrol
CA3178291A1 (en)	2016-08-05	2018-04-12	Estetra Srl	Method for the management of dysmenorrhea and menstrual pain
TWI801561B (zh)	2018-04-19	2023-05-11	比利時商依思特拉私人有限責任公司	化合物及其用於緩解絕經相關症狀的用途
JOP20200260A1 (ar)	2018-04-19	2019-10-19	Estetra Sprl	مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
EP3647413A1 (en) *	2018-10-31	2020-05-06	Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas O.A., M.P. (CIEMAT)	Improvements for performing and facilitating the recovery after hematopoietic stem cell transplantation
HU231240B1 (hu) *	2019-09-03	2022-04-28	Richter Gedeon Nyrt.	Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
IT201900017414A1 (it)	2019-09-27	2021-03-27	Ind Chimica Srl	Processo per la preparazione di (15α,16α,17β)-estra-1,3,5(10)-triene-3,15,16,17-tetrolo (Estetrolo) ed intermedi di detto processo
UY38895A (es) *	2019-09-27	2021-04-30	Ind Chimica Srl	PROCESO PARA PREPARAR (15a,16a,17ß)-ESTRA-1,3,5(10)-TRIENO-3,15,16,17-TETROL (ESTETROL) E INTERMEDIOS DE DICHO PROCESO
IT201900021879A1 (it)	2019-11-22	2021-05-22	Ind Chimica Srl	PROCESSO PER LA PREPARAZIONE DI (15α,16α,17β)-ESTRA-1,3,5(10)-TRIENE-3,15,16,17-TETROLO (ESTETROLO) ED INTERMEDI DI DETTO PROCESSO
IT202100019631A1 (it)	2021-07-23	2023-01-23	Newchem S P A	Metodo per produrre estetrolo e i suoi intermedi
WO2023021026A1 (en)	2021-08-17	2023-02-23	Aspen Oss B.V.	A synthetic pathway to estra-1,3,5(10)-triene-3,15a,16a,17b-tetrol
DE112021008305T5 (de)	2021-10-01	2024-07-25	Industriale Chimica S.R.L.	VERFAHREN ZUR HERSTELLUNG VON (15α,16α,17β)-ESTRA-1,3,5(10)-TRIENE-3,15,16,17-TETROL (ESTETROL) UND ESTETROL-MONOHYDRAT
WO2024160373A1 (en)	2023-02-02	2024-08-08	Industriale Chimica S.R.L.	PROCESS FOR PREPARING (15α,16α,17β)-ESTRA-1,3,5(10)-TRIENE-3,15,16,17-TETROL (ESTETROL) MONOHYDRATE

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW548277B (en) *	1999-07-16	2003-08-21	Akzo Nobel Nv	Orally active androgens
RU2242479C2 (ru) *	1999-12-02	2004-12-20	Акцо Нобель Н.В.	Соединения, набор, андрогенная композиция
WO2004041839A2 (en)	2002-11-08	2004-05-21	Pantarhei Bioscience B.V.	Synthesis of estetrol via estrone derived steroids
UA89964C2 (ru) *	2004-09-08	2010-03-25	Н.В. Органон	15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ
WO2012164095A1 (en)	2011-06-01	2012-12-06	Estetra S.A.	Process for the production of estetrol intermediates
DK2714710T3 (en)	2011-06-01	2016-06-27	Estetra Sprl	A process for the preparation of intermediates estetrol
EP2383279A1 (en) *	2011-07-19	2011-11-02	Pantarhei Bioscience B.V.	Process for the preparation of estetrol

2012
- 2012-10-05 SI SI201230705A patent/SI2764008T1/sl unknown
- 2012-10-05 ES ES12778664.8T patent/ES2593316T3/es active Active
- 2012-10-05 JP JP2014533925A patent/JP6196625B2/ja active Active
- 2012-10-05 US US14/349,940 patent/US8987484B2/en active Active
- 2012-10-05 HU HUE12778664A patent/HUE028963T2/en unknown
- 2012-10-05 PL PL12778664T patent/PL2764008T3/pl unknown
- 2012-10-05 AU AU2012320423A patent/AU2012320423C1/en active Active
- 2012-10-05 LT LTEP12778664.8T patent/LT2764008T/lt unknown
- 2012-10-05 SG SG11201401282PA patent/SG11201401282PA/en unknown
- 2012-10-05 RS RS20160859A patent/RS55231B1/sr unknown
- 2012-10-05 MX MX2014003723A patent/MX348917B/es active IP Right Grant
- 2012-10-05 BR BR112014008196A patent/BR112014008196B8/pt active IP Right Grant
- 2012-10-05 KR KR1020147007408A patent/KR102007874B1/ko active IP Right Grant
- 2012-10-05 DK DK12778664.8T patent/DK2764008T3/en active
- 2012-10-05 PT PT127786648T patent/PT2764008T/pt unknown
- 2012-10-05 CA CA2847813A patent/CA2847813C/en active Active
- 2012-10-05 CN CN201280049319.2A patent/CN103890001B/zh active Active
- 2012-10-05 EP EP12778664.8A patent/EP2764008B1/en active Active
- 2012-10-05 ME MEP-2016-229A patent/ME02527B/me unknown
- 2012-10-05 EA EA201490713A patent/EA024003B1/ru unknown
- 2012-10-05 WO PCT/EP2012/069761 patent/WO2013050553A1/en active Application Filing
2014
- 2014-04-02 CL CL2014000802A patent/CL2014000802A1/es unknown
- 2014-05-05 IN IN841MUN2014 patent/IN2014MN00841A/en unknown
2015
- 2015-01-13 HK HK15100344.6A patent/HK1199882A1/zh unknown
2016
- 2016-10-05 HR HRP20161282TT patent/HRP20161282T1/hr unknown
- 2016-10-10 CY CY20161101001T patent/CY1118674T1/el unknown
- 2016-10-17 SM SM201600375T patent/SMT201600375B/it unknown

Also Published As

Publication number	Publication date
EP2764008B1 (en)	2016-08-17
MX348917B (es)	2017-07-04
WO2013050553A1 (en)	2013-04-11
NZ621973A (en)	2015-08-28
LT2764008T (lt)	2016-11-10
JP6196625B2 (ja)	2017-09-13
EA201490713A1 (ru)	2014-07-30
CA2847813A1 (en)	2013-04-11
CY1118674T1 (el)	2017-07-12
KR20140083994A (ko)	2014-07-04
SI2764008T1 (sl)	2016-10-28
MX2014003723A (es)	2014-10-13
HK1199882A1 (zh)	2015-07-24
EP2764008A1 (en)	2014-08-13
AU2012320423A1 (en)	2014-03-20
HUE028963T2 (en)	2017-01-30
EA024003B1 (ru)	2016-08-31
AU2012320423C1 (en)	2018-01-25
KR102007874B1 (ko)	2019-08-06
DK2764008T3 (en)	2016-11-07
PL2764008T3 (pl)	2017-04-28
ME02527B (me)	2017-02-20
CL2014000802A1 (es)	2014-11-14
HRP20161282T1 (hr)	2016-11-18
ES2593316T3 (es)	2016-12-07
JP2014528438A (ja)	2014-10-27
BR112014008196B1 (pt)	2020-10-20
BR112014008196B8 (pt)	2020-12-15
SG11201401282PA (en)	2014-05-29
US8987484B2 (en)	2015-03-24
US20140243539A1 (en)	2014-08-28
CA2847813C (en)	2018-12-11
IN2014MN00841A (pt)	2015-07-03
RS55231B1 (sr)	2017-02-28
CN103890001B (zh)	2016-05-04
AU2012320423B2 (en)	2017-02-09
PT2764008T (pt)	2016-11-10
SMT201600375B (it)	2017-01-10
CN103890001A (zh)	2014-06-25

Publication	Publication Date	Title
BR112014008196A2 (pt)	2017-04-18	processo para a preparação de um composto
BR112014012414A8 (pt)	2018-01-23	processo para a preparação de 5-flúor-1h-pirazolopiridinas substituídas
BR112014004622A2 (pt)	2017-06-13	processo para a preparação de isocianatos
BR112015003101A2 (pt)	2017-07-04	processo para a preparação de um composto.
BR112014012243A2 (pt)	2017-05-30	processo de preparação de compostos
BR112012014490A2 (pt)	2015-09-15	processo para a preparação substituída de 1-o-acil-2-desóxi-2-fluoro-4-tio-beta-d-arabinofuranoses
BR112013031120A2 (pt)	2016-12-06	processo para a preparação de ácido fórmico
BR112013018945A2 (pt)	2017-05-02	processo para a preparação de 4-amino-5-fluoro-3-halo-6-(substituído)picolinatos.
BR112013010075A2 (pt)	2017-10-24	compostos intermediários e processo para a preparação de fingolimod
BR112014014232A2 (pt)	2018-05-22	composto e método para a preparação de um composto
BR112013030833A2 (pt)	2016-09-06	processo para a preparação de um composto de formula (i) e processo para a preparação de estetrol
BR112013008883A2 (pt)	2017-10-10	processo para a fabricação de di-hidropteridinonas
BR112014015512A2 (pt)	2017-06-13	processo para a preparação de um composto
BR112013013028A2 (pt)	2016-08-09	processo para a preparação de derivados de carbamato de fenila
BR112014010997A2 (pt)	2017-06-06	processo para o preparo de ß-glicosídeos de c-arila
BR112014001769A2 (pt)	2017-02-21	processo para a preparação de 1,4-ciclo-hexanodimetanol
BR112014028589A2 (pt)	2017-07-25	processo para fabricação de compostos de ciclopentilpirimidina hidroxilada
BR112014003336A2 (pt)	2017-03-14	processo para a preparação de complexos de 68ga
BR112013022548A2 (pt)	2016-12-06	processo para a preparação de aminas primárias
BR112015000987A2 (pt)	2017-06-27	processo para a preparação de 5-fluoro-1h-pirazóis
BR112014010327A2 (pt)	2017-05-09	processo para a preparação de compostos
BR112014014052A2 (pt)	2017-06-13	processo para a preparação de 5-hidroximetilfurfural
BR112012001731A2 (pt)	2015-09-01	Processo para a preparação de 1-benzil-3-hidroximetil-1h-indazol
BR112014009437A2 (pt)	2017-04-11	processo para preparar um composto, composto e uso de um composto
BR112014011737A2 (pt)	2017-10-24	processo para ligação de elementos funcionais a um eixo

Legal Events

Date	Code	Title	Description
2018-05-15	B25G	Requested change of headquarter approved	Owner name: ESTETRA S.P.R.L. (BE)
2018-05-22	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2019-12-17	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2020-03-10	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
2020-04-07	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2020-08-11	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2020-10-20	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/10/2012, OBSERVADAS AS CONDICOES LEGAIS.
2020-12-15	B16C	Correction of notification of the grant [chapter 16.3 patent gazette]	Free format text: REF. RPI 2598 DE 20/10/2020 QUANTO AO TITULO E O ENDERECO.
2023-11-07	B25A	Requested transfer of rights approved	Owner name: MITHRA RECHERCHE ET DEVELOPPEMENT SA (BE)