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BR0315275A - Antibodies that bind to erythropoietin receptor - Google Patents

Antibodies that bind to erythropoietin receptor

Info

Publication number
BR0315275A
BR0315275A BR0315275-8A BR0315275A BR0315275A BR 0315275 A BR0315275 A BR 0315275A BR 0315275 A BR0315275 A BR 0315275A BR 0315275 A BR0315275 A BR 0315275A
Authority
BR
Brazil
Prior art keywords
antibodies
bind
erythropoietin receptor
relates
present
Prior art date
Application number
BR0315275-8A
Other languages
Portuguese (pt)
Inventor
Peter J Devries
Larry L Green
David H Ostrow
Edward B Reilly
James Wieler
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/269,711 external-priority patent/US20040071694A1/en
Priority claimed from US10/684,109 external-priority patent/US7396913B2/en
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BR0315275A publication Critical patent/BR0315275A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"ANTICORPOS QUE SE LIGAM A RECEPTOR DE ERITROPOIETINA". A presente invenção se refere a anticorpos e a fragmentos destes anticorpos que se ligam a um receptor de eritropoietina e o ativam. A presente invenção também se refere a métodos de modulação da atividade endógena de um receptor de eritropoietina em um mamífero empregando-se tais anticorpos, assim como a composições farmacêuticas contendo tais anticorpos."Antibodies that bind to the erythropoietin receptor". The present invention relates to antibodies and fragments of these antibodies that bind to and activate an erythropoietin receptor. The present invention also relates to methods of modulating the endogenous activity of an erythropoietin receptor in a mammal using such antibodies, as well as pharmaceutical compositions containing such antibodies.

BR0315275-8A 2002-10-14 2003-10-14 Antibodies that bind to erythropoietin receptor BR0315275A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/269,711 US20040071694A1 (en) 2002-10-14 2002-10-14 Erythropoietin receptor binding antibodies
US10/684,109 US7396913B2 (en) 2002-10-14 2003-10-10 Erythropoietin receptor binding antibodies
PCT/US2003/032243 WO2004035603A2 (en) 2002-10-14 2003-10-14 Erythropoietin receptor binding antibodies

Publications (1)

Publication Number Publication Date
BR0315275A true BR0315275A (en) 2005-08-30

Family

ID=32109805

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0315275-8A BR0315275A (en) 2002-10-14 2003-10-14 Antibodies that bind to erythropoietin receptor

Country Status (13)

Country Link
EP (1) EP1578779A4 (en)
JP (2) JP4411472B2 (en)
KR (1) KR20050059263A (en)
CN (1) CN103524618A (en)
AU (2) AU2003282588B2 (en)
BR (1) BR0315275A (en)
CA (1) CA2501984C (en)
MX (1) MXPA05003997A (en)
NZ (1) NZ539263A (en)
PL (1) PL379985A1 (en)
TW (1) TWI320716B (en)
WO (1) WO2004035603A2 (en)
ZA (1) ZA201004902B (en)

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Also Published As

Publication number Publication date
CA2501984C (en) 2011-04-26
MXPA05003997A (en) 2005-06-22
TWI320716B (en) 2010-02-21
CA2501984A1 (en) 2004-04-29
NZ539263A (en) 2009-07-31
AU2003282588B2 (en) 2010-06-03
ZA201004902B (en) 2012-06-27
WO2004035603A2 (en) 2004-04-29
CN103524618A (en) 2014-01-22
EP1578779A4 (en) 2011-11-16
KR20050059263A (en) 2005-06-17
TW200418505A (en) 2004-10-01
JP2009149665A (en) 2009-07-09
EP1578779A2 (en) 2005-09-28
WO2004035603A3 (en) 2006-04-27
AU2010214778A1 (en) 2010-09-23
AU2003282588A1 (en) 2004-05-04
JP4411472B2 (en) 2010-02-10
JP2006523083A (en) 2006-10-12
PL379985A1 (en) 2006-11-27

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal: dismissal of application maintained