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BR0109483A - Pró-drogas de derivados de imidazopiridina - Google Patents

Pró-drogas de derivados de imidazopiridina

Info

Publication number
BR0109483A
BR0109483A BR0109483-1A BR0109483A BR0109483A BR 0109483 A BR0109483 A BR 0109483A BR 0109483 A BR0109483 A BR 0109483A BR 0109483 A BR0109483 A BR 0109483A
Authority
BR
Brazil
Prior art keywords
imidazopyridine derivative
derivative prodrugs
prodrugs
imidazopyridine
substituents
Prior art date
Application number
BR0109483-1A
Other languages
English (en)
Inventor
Wolfgang-Alexander Simon
Stefan Postius
Reinhard Huber
Wolfgang Kromer
Joerg Senn-Bilfinger
Wilm Buhr
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of BR0109483A publication Critical patent/BR0109483A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

"PRó-DROGAS DE DERIVADOS DE IMIDAZOPIRIDINA". Os compostos de fórmula (1), em que os substituintes têm os significados mencionados na descrição, são adequados para a prevenção e o tratamento de doenças gastrointestinais.
BR0109483-1A 2000-03-29 2001-03-28 Pró-drogas de derivados de imidazopiridina BR0109483A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00106695 2000-03-29
PCT/EP2001/003514 WO2001072756A1 (en) 2000-03-29 2001-03-28 Prodrugs of imidazopyridine derivatives

Publications (1)

Publication Number Publication Date
BR0109483A true BR0109483A (pt) 2003-06-10

Family

ID=8168271

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0109483-1A BR0109483A (pt) 2000-03-29 2001-03-28 Pró-drogas de derivados de imidazopiridina

Country Status (26)

Country Link
US (2) US20030125327A1 (pt)
EP (1) EP1313740B1 (pt)
JP (1) JP2003528878A (pt)
KR (1) KR100860627B1 (pt)
CN (1) CN1214030C (pt)
AT (1) ATE311389T1 (pt)
AU (1) AU783633B2 (pt)
BR (1) BR0109483A (pt)
CA (1) CA2404474A1 (pt)
CZ (1) CZ20023194A3 (pt)
DE (1) DE60115466T2 (pt)
DK (1) DK1313740T3 (pt)
EA (1) EA005597B1 (pt)
ES (1) ES2253376T3 (pt)
HK (1) HK1056175A1 (pt)
HR (1) HRP20020854A2 (pt)
HU (1) HUP0302331A2 (pt)
IL (2) IL151200A0 (pt)
MX (1) MXPA02009551A (pt)
NO (1) NO20024662D0 (pt)
NZ (1) NZ520837A (pt)
PL (1) PL365116A1 (pt)
SI (1) SI1313740T1 (pt)
SK (1) SK286850B6 (pt)
WO (1) WO2001072756A1 (pt)
ZA (1) ZA200207637B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK13872002A3 (sk) * 2000-03-29 2003-02-04 Altana Pharma Ag Alkylové imidazopyridínové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie
NZ525281A (en) 2000-10-25 2004-11-26 Altana Pharma Ag Polysubstituted imidazopyridines as gastric secretion inhibitors
US20050020637A1 (en) * 2001-11-19 2005-01-27 Wolfgang-Alexander Simon Agents for the treatment of airway disorders
EA008375B1 (ru) 2002-02-15 2007-04-27 Алтана Фарма Аг Трициклические n-ацильные соединения
TWI295575B (en) * 2002-04-24 2008-04-11 Altana Pharma Ag Nitrosated imidazopyridines
CN1652822A (zh) * 2002-05-07 2005-08-10 奥坦纳医药公司 用于治疗气道病症的可逆质子泵抑制剂和气道治疗剂的新组合
AU2003288071A1 (en) 2002-11-19 2004-06-15 Altana Pharma Ag 8-substituted imidazopyridines
BR0316752A (pt) * 2002-12-20 2005-10-25 Altana Pharma Ag Silil éteres
WO2004071391A2 (en) * 2003-02-17 2004-08-26 Altana Pharma Ag Imidazopyridines containing combinations and their use in treating gastrointestinal inflammatory disorders
AR044129A1 (es) 2003-05-06 2005-08-24 Altana Pharma Ag Compuestos intermedios de imidazopiridina. proceso de preparacion.
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
RS20050868A (en) * 2003-05-27 2007-08-03 Altana Pharma Ag., Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
CN101361738A (zh) 2003-11-03 2009-02-11 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2-a]吡啶衍生物
AR046893A1 (es) * 2003-12-16 2005-12-28 Altana Pharma Ag Bencimidazoles triciclicos
AU2004298453A1 (en) 2003-12-19 2005-06-30 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
EP1831150A1 (en) * 2004-07-23 2007-09-12 DSMIP Assets B.V. Process for the preparation of (2r, 3r)-2-hydroxy-3-amino-3-aryl-propionamide and (2r, 3r)-2-hydroxy-3-amino-3-aryl-propionic acid alkyl ester
AU2005291284A1 (en) * 2004-10-01 2006-04-13 Altana Pharma Ag Substituted tricyclic benzimidazoles
WO2011004882A1 (ja) 2009-07-09 2011-01-13 ラクオリア創薬株式会社 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
US4673679A (en) * 1986-05-14 1987-06-16 E. I. Du Pont De Nemours And Company Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration
WO1992021341A1 (en) * 1991-05-31 1992-12-10 Pfizer Inc. Use of rapamycin prodrugs as immunosuppressant agents
DE4308095A1 (de) * 1993-03-13 1994-09-15 Hoechst Ag Prodrug-Derivate von Arzneimittelwirkstoffen mit Hydroxylgruppen, Verfahren zu deren Herstellung und ihre Verwendung
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
US6073004A (en) 1996-12-17 2000-06-06 Ericsson Inc. Emergency call initiator
WO1998042707A1 (en) * 1997-03-24 1998-10-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyrido compounds
CU23088A3 (es) * 1997-03-24 2005-10-19 Altana Pharma Ag Compuestos de tetra-hidropiridina.
CN101255164A (zh) * 1997-05-28 2008-09-03 奥坦纳医药公司 稠合的二氢吡喃类化合物及其用途
GEP20032926B (en) * 1998-09-23 2003-03-25 Altana Pharma Ag Tetrahydropyridoethers
AU1044500A (en) * 1998-11-03 2000-05-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Imidazonaphthyridines
SK13872002A3 (sk) 2000-03-29 2003-02-04 Altana Pharma Ag Alkylové imidazopyridínové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie

Also Published As

Publication number Publication date
CA2404474A1 (en) 2001-10-04
ATE311389T1 (de) 2005-12-15
MXPA02009551A (es) 2004-05-14
CZ20023194A3 (cs) 2003-01-15
IL151200A0 (en) 2003-04-10
US20030125327A1 (en) 2003-07-03
PL365116A1 (en) 2004-12-27
KR100860627B1 (ko) 2008-09-29
EP1313740A1 (en) 2003-05-28
ES2253376T3 (es) 2006-06-01
US7189736B2 (en) 2007-03-13
JP2003528878A (ja) 2003-09-30
HK1056175A1 (en) 2004-02-06
HUP0302331A2 (hu) 2003-12-29
AU6016601A (en) 2001-10-08
DE60115466D1 (de) 2006-01-05
SK13852002A3 (sk) 2003-02-04
IL151200A (en) 2009-11-18
EA200200875A1 (ru) 2003-04-24
NO20024662L (no) 2002-09-27
EP1313740B1 (en) 2005-11-30
US20040198764A1 (en) 2004-10-07
CN1214030C (zh) 2005-08-10
NZ520837A (en) 2005-01-28
EA005597B1 (ru) 2005-04-28
ZA200207637B (en) 2004-04-08
SK286850B6 (sk) 2009-06-05
HRP20020854A2 (en) 2004-12-31
SI1313740T1 (sl) 2006-04-30
WO2001072756A1 (en) 2001-10-04
AU783633B2 (en) 2005-11-17
DE60115466T2 (de) 2006-07-20
CN1426414A (zh) 2003-06-25
KR20020084262A (ko) 2002-11-04
DK1313740T3 (da) 2006-04-03
NO20024662D0 (no) 2002-09-27

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.