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BR0011880A - Method for the treatment of co-morbid conditions associated with obesity, compound, product, use of a compound, and pharmaceutical composition - Google Patents

Method for the treatment of co-morbid conditions associated with obesity, compound, product, use of a compound, and pharmaceutical composition

Info

Publication number
BR0011880A
BR0011880A BR0011880-0A BR0011880A BR0011880A BR 0011880 A BR0011880 A BR 0011880A BR 0011880 A BR0011880 A BR 0011880A BR 0011880 A BR0011880 A BR 0011880A
Authority
BR
Brazil
Prior art keywords
compound
treatment
obesity
conditions associated
pharmaceutical composition
Prior art date
Application number
BR0011880-0A
Other languages
Portuguese (pt)
Inventor
David John Heal
Original Assignee
Knoll Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Gmbh filed Critical Knoll Gmbh
Publication of BR0011880A publication Critical patent/BR0011880A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Addiction (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"MéTODO PARA O TRATAMENTO DE CONDIçõES CO-MóRBIDAS ASSOCIADAS COM OBESIDADE, COMPOSTO , PRODUTO, USO DE UM COMPOSTO, E, COMPOSIçãO FARMACêUTICA". Método para o tratamento de condições co-mórbidas associadas com obesidade em humanos necessitados de tal tratamento que compreende administração ao humano de quantidade terapeuticamente efetiva do composto de fórmula (I): que inclui enanciómeros e sais farmaceuticamente aceitáveis dos mesmos, em que R~ 1~ e R~ 2~ são independentemente H ou metila, e quantidade terapeuticamente efetiva do composto de fórmula (II) em que o composto de fórmula (I) e o composto de fórmula (II): são administrados simultaneamente, separadamente ou seq³encialmente."METHOD FOR THE TREATMENT OF COMBOSIBLE CONDITIONS ASSOCIATED WITH OBESITY, COMPOUND, PRODUCT, USE OF A COMPOUND, AND PHARMACEUTICAL COMPOSITION". Method for the treatment of co-morbid conditions associated with obesity in humans in need of such treatment which comprises administering to the human a therapeutically effective amount of the compound of formula (I): which includes enantiomers and pharmaceutically acceptable salts thereof, where R ~ 1 ~ and R ~ 2 ~ are independently H or methyl, and therapeutically effective amount of the compound of formula (II) wherein the compound of formula (I) and the compound of formula (II): are administered simultaneously, separately or sequentially.

BR0011880-0A 1999-06-24 2000-06-16 Method for the treatment of co-morbid conditions associated with obesity, compound, product, use of a compound, and pharmaceutical composition BR0011880A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9914744.9A GB9914744D0 (en) 1999-06-24 1999-06-24 Therapeutic agents
PCT/EP2000/005542 WO2001000205A1 (en) 1999-06-24 2000-06-16 Pharmaceutical composition containing sibutramine and orlistat

Publications (1)

Publication Number Publication Date
BR0011880A true BR0011880A (en) 2002-03-19

Family

ID=10855955

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0011880-0A BR0011880A (en) 1999-06-24 2000-06-16 Method for the treatment of co-morbid conditions associated with obesity, compound, product, use of a compound, and pharmaceutical composition

Country Status (21)

Country Link
EP (1) EP1187606A1 (en)
JP (1) JP2003503349A (en)
KR (1) KR20020015357A (en)
CN (1) CN1358092A (en)
AU (1) AU5533200A (en)
BG (1) BG106180A (en)
BR (1) BR0011880A (en)
CA (1) CA2375972A1 (en)
CZ (1) CZ20014613A3 (en)
GB (1) GB9914744D0 (en)
HK (1) HK1049278A1 (en)
HU (1) HUP0201878A3 (en)
IL (1) IL147079A0 (en)
MX (1) MXPA01012936A (en)
NO (1) NO20016224L (en)
PL (1) PL352402A1 (en)
RU (1) RU2229289C2 (en)
SK (1) SK18242001A3 (en)
TR (1) TR200103699T2 (en)
WO (1) WO2001000205A1 (en)
ZA (1) ZA200109989B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696495B2 (en) * 1998-12-02 2004-02-24 Snowden Pharmaceuticals, Llc Treatment of disorders secondary to organic impairments
US20040214804A1 (en) * 2003-04-25 2004-10-28 Pharmacia Corporation Combination of an aldosterone receptor antagonist and an anti-obesity agent
BRPI0517434A (en) 2004-10-25 2008-10-07 Solvay Pharm Gmbh pharmaceutical compositions comprising cannabinoid cb1 receptor antagonists and potassium channel openers for the treatment of type i diabetes mellitus, obesity and related conditions
US8604244B2 (en) 2010-07-02 2013-12-10 Reviva Pharmaceuticals, Inc. Compositions, synthesis, and methods of using cycloalkylmethylamine derivatives
CN101626768B (en) 2006-09-15 2013-08-21 雷维瓦药品公司 Synthesis, methods of using, and compositions of cycloalkylmethylamines
US20100099773A1 (en) * 2006-11-22 2010-04-22 Jae-Sun Kim Inclusion complex of sibutramine and beta-cyclodextrin
CN101890017A (en) * 2009-05-22 2010-11-24 北京奥萨医药研究中心有限公司 Medicament composition containing sibutramine and stanin fat-reducing medicament and application thereof
MX336980B (en) * 2010-12-21 2016-02-09 Senosiain S A De C V Lab Combination and composition for treating obesity.
RU2642074C2 (en) 2011-12-30 2018-01-24 Ревива Фармасьютикалс, Инк. Compositions, synthesis and methods for application of phenylcycloalkylmethylamine derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9727131D0 (en) * 1997-12-24 1998-02-25 Knoll Ag Therapeutic agents

Also Published As

Publication number Publication date
MXPA01012936A (en) 2004-04-21
JP2003503349A (en) 2003-01-28
GB9914744D0 (en) 1999-08-25
NO20016224L (en) 2002-02-12
HUP0201878A3 (en) 2005-04-28
HUP0201878A2 (en) 2003-08-28
ZA200109989B (en) 2003-02-26
AU5533200A (en) 2001-01-31
CA2375972A1 (en) 2001-01-04
RU2229289C2 (en) 2004-05-27
BG106180A (en) 2002-08-30
SK18242001A3 (en) 2003-02-04
EP1187606A1 (en) 2002-03-20
IL147079A0 (en) 2002-08-14
WO2001000205A1 (en) 2001-01-04
KR20020015357A (en) 2002-02-27
TR200103699T2 (en) 2002-04-22
CN1358092A (en) 2002-07-10
CZ20014613A3 (en) 2003-04-16
PL352402A1 (en) 2003-08-25
NO20016224D0 (en) 2001-12-19
HK1049278A1 (en) 2003-05-09

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Legal Events

Date Code Title Description
PC Transfer

Owner name: ABBOTT GMBH & CO. KG (DE)

B25L Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled
B25A Requested transfer of rights approved

Free format text: ABBOTT GMBH (DE)

B25D Requested change of name of applicant approved
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.