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BR0010916A - nucleic acid, probe or nucleotide primer, processes and kits for amplifying a nucleic acid, for detecting the presence of a nucleic acid and a polypeptide, for selecting a molecule or candidate substance that interacts with a polypeptide, recombinant vector , recombinant host cell, polypeptide, and antibody - Google Patents

nucleic acid, probe or nucleotide primer, processes and kits for amplifying a nucleic acid, for detecting the presence of a nucleic acid and a polypeptide, for selecting a molecule or candidate substance that interacts with a polypeptide, recombinant vector , recombinant host cell, polypeptide, and antibody

Info

Publication number
BR0010916A
BR0010916A BR0010916-9A BR0010916A BR0010916A BR 0010916 A BR0010916 A BR 0010916A BR 0010916 A BR0010916 A BR 0010916A BR 0010916 A BR0010916 A BR 0010916A
Authority
BR
Brazil
Prior art keywords
nucleic acid
polypeptide
recombinant
kits
antibody
Prior art date
Application number
BR0010916-9A
Other languages
Portuguese (pt)
Inventor
Patrice Denefle
Marie-Francoise Rosier-Montus
Isabelle Arnould-Requingne
Catherine Prades
Christian Clepet
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9906587A external-priority patent/FR2794131B1/en
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of BR0010916A publication Critical patent/BR0010916A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"áCIDO NUCLEICO, SONDA OU INICIADOR DE NUCLEOTìDEO, PROCESSOS E KITS PARA AMPLIFICAçãO DE UM áCIDO NUCLEICO, PARA DETECçãO DA PRESENçA DE UM áCIDO NUCLéICO E DE UM POLIPEPTìDEO, PARA SELEçãO DE UMA MOLéCULA OU DE UMA SUBSTâNCIA CANDIDATA QUE INTERAGE COM UM POLIPEPTìDEO, VETOR RECOMBINANTE, CéLULA HOSPEDEIRA RECOMBINANTE, POLIPEPTìDEO, E, ANTICORPO". A presente invenção refere-se a ácidos nucleicos expressos a partir de genes localizados no genoma humano na região 9q31-34 do cromossoma 9, capazes de estarem implicados nas doenças geneticamente ligadas a este local cromossómico, principalmente as afecções do metabolismo das lipoproteinas plasmáticas, mais particularmente o transporte inverso do colesterol. A invenção refere-se também a polipeptídeos codificados por determinados destes ácidos nucleicos bem como dos anticorpos dirigidos especificamente contra tais polipeptídeos, úteis como reagentes de diagnóstico. A invenção refere-se, finalmente, a vetores e células hospedeiras recombinantes compreendendo estes ácidos nucleicos ou fragmentos dos mesmos."NUCLEIC ACID, NUCLEOTIDE PROBE OR INITIATOR, PROCESSES AND KITS FOR AMPLIFICATION OF A NUCLEIC ACID, FOR DETECTION OF THE PRESENCE OF A NUCLEIC ACID AND A POLYPEEPTIDE, FOR THE SELECTION OF A MOLECULE OR A SUE RECOMBINANT, RECOMBINANT HOSTING CELL, POLYPEPTIDE, AND ANTIBODY ". The present invention relates to nucleic acids expressed from genes located in the human genome in the 9q31-34 region of chromosome 9, capable of being implicated in diseases genetically linked to this chromosomal site, mainly disorders of plasma lipoprotein metabolism, more particularly cholesterol reverse transport. The invention also relates to polypeptides encoded by certain of these nucleic acids as well as antibodies specifically directed against such polypeptides, useful as diagnostic reagents. Finally, the invention relates to vectors and recombinant host cells comprising these nucleic acids or fragments thereof.

BR0010916-9A 1999-05-25 2000-05-25 nucleic acid, probe or nucleotide primer, processes and kits for amplifying a nucleic acid, for detecting the presence of a nucleic acid and a polypeptide, for selecting a molecule or candidate substance that interacts with a polypeptide, recombinant vector , recombinant host cell, polypeptide, and antibody BR0010916A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9906587A FR2794131B1 (en) 1999-05-25 1999-05-25 GENE EXPRESSION PRODUCTS INVOLVED IN CONDITIONS ASSOCIATED WITH THE METABOLISM OF CHOLESTEROL
US13945099P 1999-06-16 1999-06-16
PCT/FR2000/001426 WO2000071710A2 (en) 1999-05-25 2000-05-25 Expression products of genes involved in diseases related to cholesterol metabolism

Publications (1)

Publication Number Publication Date
BR0010916A true BR0010916A (en) 2002-02-19

Family

ID=26234967

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0010916-9A BR0010916A (en) 1999-05-25 2000-05-25 nucleic acid, probe or nucleotide primer, processes and kits for amplifying a nucleic acid, for detecting the presence of a nucleic acid and a polypeptide, for selecting a molecule or candidate substance that interacts with a polypeptide, recombinant vector , recombinant host cell, polypeptide, and antibody

Country Status (11)

Country Link
EP (1) EP1183350A2 (en)
JP (1) JP2003518918A (en)
KR (1) KR20020033627A (en)
AU (1) AU4931800A (en)
BR (1) BR0010916A (en)
CA (1) CA2371500A1 (en)
HU (1) HUP0203164A2 (en)
IL (1) IL145835A0 (en)
MX (1) MXPA01011882A (en)
NO (1) NO20015729L (en)
WO (1) WO2000071710A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE364696T1 (en) 1999-03-15 2007-07-15 Univ British Columbia ABC1 POLYPEPTIDES AND METHODS AND REAGENTS FOR MODULATING CHOLESTEROL CONTENT
MXPA03000979A (en) 2000-08-01 2004-08-12 Amgen Inc C3b/C4b COMPLEMENT RECEPTOR-LIKE MOLECULES AND USES THEREOF.
AT413701B (en) * 2001-11-06 2006-05-15 Bmt Medizinische Forschung Und STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF CDW92
US20100111851A1 (en) * 2007-01-05 2010-05-06 The University Of Tokyo Diagnosis and treatment of cancer by using anti-prg-3 antibody
US8680243B2 (en) 2007-11-14 2014-03-25 Chugai Seiyaku Kabushiki Kaisha Diagnosis and treatment of cancer using anti-GPR49 antibody

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0941366A2 (en) * 1996-11-06 1999-09-15 Whitehead Institute For Biomedical Research Biallelic markers

Also Published As

Publication number Publication date
CA2371500A1 (en) 2000-11-30
JP2003518918A (en) 2003-06-17
KR20020033627A (en) 2002-05-07
HUP0203164A2 (en) 2002-12-28
EP1183350A2 (en) 2002-03-06
AU4931800A (en) 2000-12-12
WO2000071710A3 (en) 2001-05-17
NO20015729D0 (en) 2001-11-23
NO20015729L (en) 2002-01-22
IL145835A0 (en) 2002-07-25
MXPA01011882A (en) 2002-05-06
WO2000071710A2 (en) 2000-11-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A, E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1929 DE 26/12/2007.