BG49827A3 - Method for preparing a clean byologic active recombinative human colonium stimulating factor - Google Patents
Method for preparing a clean byologic active recombinative human colonium stimulating factorInfo
- Publication number
- BG49827A3 BG49827A3 BG086469A BG8646988A BG49827A3 BG 49827 A3 BG49827 A3 BG 49827A3 BG 086469 A BG086469 A BG 086469A BG 8646988 A BG8646988 A BG 8646988A BG 49827 A3 BG49827 A3 BG 49827A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- active
- stimulating factor
- colonium
- byologic
- recombinative
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000004936 stimulating effect Effects 0.000 title 1
- 102000007644 Colony-Stimulating Factors Human genes 0.000 abstract 1
- 108010071942 Colony-Stimulating Factors Proteins 0.000 abstract 1
- 239000000539 dimer Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4017487A | 1987-04-16 | 1987-04-16 | |
US11400187A | 1987-10-27 | 1987-10-27 | |
PCT/US1988/001189 WO1988008003A1 (fr) | 1987-04-16 | 1988-04-18 | Production de csf-1 humain recombinant produit par des cellules bacteriennes, biologiquement actif, purifie |
Publications (1)
Publication Number | Publication Date |
---|---|
BG49827A3 true BG49827A3 (en) | 1992-02-14 |
Family
ID=26716797
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG086469A BG49827A3 (en) | 1987-04-16 | 1988-12-16 | Method for preparing a clean byologic active recombinative human colonium stimulating factor |
Country Status (10)
Country | Link |
---|---|
EP (2) | EP0309569B1 (fr) |
JP (1) | JP2656964B2 (fr) |
AT (2) | ATE167192T1 (fr) |
AU (1) | AU610182B2 (fr) |
BG (1) | BG49827A3 (fr) |
DE (2) | DE3856203T2 (fr) |
FI (1) | FI96872C (fr) |
IL (1) | IL86090A (fr) |
NO (1) | NO300067B1 (fr) |
WO (1) | WO1988008003A1 (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5650297A (en) * | 1986-09-17 | 1997-07-22 | Otsuka Pharmaceutical Co., Ltd. | DNA encoding human colony-stimulating factors |
US4931543A (en) * | 1987-05-11 | 1990-06-05 | Cetus Corporation | Process for recovering microbially produced interleukin-2 |
EP0411033B1 (fr) * | 1988-04-29 | 1994-09-07 | Genetics Institute, Inc. | Formulations stables pendant le stockage du m-csf dimerique homogene |
EP0410751B1 (fr) * | 1989-07-27 | 1996-04-10 | Denki Kagaku Kogyo Kabushiki Kaisha | Gène codant pour M-CSF et systèmes recombinants pour cela |
GB8927546D0 (en) * | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
AU8417091A (en) * | 1990-08-20 | 1992-03-17 | Novo Nordisk A/S | Biologically active compound, a process for the preparation thereof and use of the same |
DK0547102T3 (da) * | 1990-09-05 | 1999-04-19 | Natinco Nv | Opløseliggørelse af proteiner på aktiv form |
US5288931A (en) * | 1991-12-06 | 1994-02-22 | Genentech, Inc. | Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation |
WO1993025687A1 (fr) * | 1992-06-09 | 1993-12-23 | Chiron Corporation | Cristallisation du m-csf |
AU661914B2 (en) * | 1992-08-18 | 1995-08-10 | Jean-Louis Odore | Support structure for a shelter cover |
JPH08502661A (ja) * | 1993-08-04 | 1996-03-26 | チバ−ガイギー アクチェンゲゼルシャフト | 高分子量デスルファトヒルジン |
US5407810A (en) * | 1993-08-20 | 1995-04-18 | Genentech, Inc. | Aqueous multiple-phase isolation of polypeptide |
US5663304A (en) * | 1993-08-20 | 1997-09-02 | Genentech, Inc. | Refolding of misfolded insulin-like growth factor-I |
TW517059B (en) | 1994-07-25 | 2003-01-11 | Ciba Geigy Ag | New process for the production of biologically active protein |
FR2796071B1 (fr) * | 1999-07-08 | 2001-09-07 | Hoechst Marion Roussel Inc | Procede de purification de facteur de stimulation de colonies de granulocytes |
US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
DE102004041639A1 (de) * | 2004-08-27 | 2006-03-02 | Bioceuticals Arzneimittel Ag | Verfahren zur Gewinnung von biologisch aktivem humanen G-CSF aus Inclusion Bodies |
MX2011013898A (es) | 2009-06-22 | 2012-05-22 | Amgen Inc | Proteínas replegadas que usan un estado de oxido-reduccion quimicamente controlado. |
EP2445924B2 (fr) | 2009-06-25 | 2023-12-13 | Amgen Inc. | Procédés de purification par capture de protéines exprimées dans un système non mammifère |
DE202009019091U1 (de) | 2009-12-21 | 2016-05-23 | Agilent Technologies, Inc. - A Delaware Corporation - | Fittingelement mit frontseitiger Einlage |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR79124B (fr) * | 1982-12-22 | 1984-10-02 | Genentech Inc | |
AU594045B2 (en) * | 1985-02-05 | 1990-03-01 | Chiron Corporation | Recombinant colony stimulating factor-1 |
HU212277B (en) * | 1986-05-06 | 1996-04-29 | Genetics Inst | Process for producing m-csf |
DK54589A (da) * | 1988-02-08 | 1989-08-09 | Otsuka Pharma Co Ltd | Humane kolonistmulerende faktorer |
-
1988
- 1988-04-15 IL IL86090A patent/IL86090A/xx not_active IP Right Cessation
- 1988-04-18 JP JP63503965A patent/JP2656964B2/ja not_active Expired - Lifetime
- 1988-04-18 EP EP88904086A patent/EP0309569B1/fr not_active Expired - Lifetime
- 1988-04-18 AU AU17124/88A patent/AU610182B2/en not_active Expired
- 1988-04-18 EP EP97202737A patent/EP0818466B1/fr not_active Expired - Lifetime
- 1988-04-18 AT AT88904086T patent/ATE167192T1/de not_active IP Right Cessation
- 1988-04-18 AT AT97202737T patent/ATE301133T1/de not_active IP Right Cessation
- 1988-04-18 DE DE3856203T patent/DE3856203T2/de not_active Expired - Lifetime
- 1988-04-18 WO PCT/US1988/001189 patent/WO1988008003A1/fr active IP Right Grant
- 1988-04-18 DE DE3856581T patent/DE3856581T2/de not_active Expired - Lifetime
- 1988-12-14 NO NO885555A patent/NO300067B1/no not_active IP Right Cessation
- 1988-12-15 FI FI885807A patent/FI96872C/fi not_active IP Right Cessation
- 1988-12-16 BG BG086469A patent/BG49827A3/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0818466A3 (fr) | 1998-03-25 |
WO1988008003A1 (fr) | 1988-10-20 |
EP0309569A1 (fr) | 1989-04-05 |
FI96872B (fi) | 1996-05-31 |
DE3856581D1 (de) | 2005-09-29 |
FI96872C (fi) | 1996-09-10 |
EP0818466A2 (fr) | 1998-01-14 |
NO300067B1 (no) | 1997-04-01 |
ATE167192T1 (de) | 1998-06-15 |
IL86090A0 (en) | 1988-09-30 |
DE3856581T2 (de) | 2006-05-24 |
JP2656964B2 (ja) | 1997-09-24 |
EP0309569B1 (fr) | 1998-06-10 |
DE3856203T2 (de) | 1998-10-08 |
NO885555L (no) | 1989-01-11 |
AU610182B2 (en) | 1991-05-16 |
NO885555D0 (no) | 1988-12-14 |
EP0818466B1 (fr) | 2005-08-03 |
DE3856203D1 (de) | 1998-07-16 |
IL86090A (en) | 1993-03-15 |
JPH01503440A (ja) | 1989-11-22 |
FI885807A (fi) | 1988-12-15 |
ATE301133T1 (de) | 2005-08-15 |
AU1712488A (en) | 1988-11-04 |
FI885807A0 (fi) | 1988-12-15 |
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