BE2013C004I2 - Phosphonocephem derivatives, process for the preparation of the same, and use thereof - Google Patents

Phosphonocephem derivatives, process for the preparation of the same, and use thereof

Info

Publication number: BE2013C004I2
Authority: BE; Belgium
Prior art keywords: group; substituted; preparation; same; hydrogen atom
Prior art date: 1997-12-19

Application number

BE2013C004C

Other languages

English (en)

French (fr)

Original Assignee

Takeda Pharmaceuticals Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-19

Filing date

2013-01-08

Publication date

2018-01-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18417716&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE2013C004(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2013-01-08 Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co

2018-01-29 Publication of BE2013C004I2 publication Critical patent/BE2013C004I2/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65613—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)

BE2013C004C 1997-12-19 2013-01-08 Phosphonocephem derivatives, process for the preparation of the same, and use thereof BE2013C004I2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP35149997		1997-12-19
PCT/JP1998/005709 WO1999032497A1 (fr)	1997-12-19	1998-12-17	Derives de phosphonocephem, leur procede de preparation et leur utilisation

Publications (1)

Publication Number	Publication Date
BE2013C004I2 true BE2013C004I2 (en)	2018-01-29

Family

ID=18417716

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE2013C004C BE2013C004I2 (en)	1997-12-19	2013-01-08	Phosphonocephem derivatives, process for the preparation of the same, and use thereof

Country Status (19)

Country	Link
US (1)	US6417175B1 (el)
EP (2)	EP2080765A1 (el)
JP (3)	JP3467418B2 (el)
KR (1)	KR100384047B1 (el)
CN (2)	CN1679595B (el)
AT (1)	ATE430155T1 (el)
AU (1)	AU1683299A (el)
BE (1)	BE2013C004I2 (el)
CA (1)	CA2314564C (el)
CY (2)	CY1109276T1 (el)
DE (1)	DE69840796D1 (el)
DK (1)	DK1043327T3 (el)
ES (1)	ES2325139T3 (el)
FR (1)	FR13C0008I2 (el)
LU (1)	LU92134I2 (el)
NL (1)	NL300568I1 (el)
PT (1)	PT1043327E (el)
TW (1)	TW473479B (el)
WO (1)	WO1999032497A1 (el)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT1310502E (pt) *	2000-08-10	2009-07-31	Takeda Pharmaceutical	Composto de fosfonocefem
US20070238720A1 (en) *	2005-05-10	2007-10-11	Hopkins Scott J	Method for reducing the risk of or preventing infection due to surgical or invasive medical procedures
US20070238719A1 (en) *	2005-05-10	2007-10-11	Hopkins Scott J	Method for reducing the risk of or preventing infection due to surgical or invasive medical procedures
US20070249577A1 (en) *	2005-05-10	2007-10-25	Hopkins Scott J	Method for reducing the risk of or preventing infection due to surgical or invasive medical procedures
CN101456871B (zh) *	2007-06-22	2011-01-12	山东轩竹医药科技有限公司	含有巯基噻唑的头孢菌素衍生物
AU2008302201A1 (en)	2007-09-21	2009-03-26	Astrazeneca Ab	Soluble dosage forms containing cephem derivatives suitable for parenteral administration
EP2889034B1 (en) *	2008-08-28	2019-02-27	Pfizer Anti-Infectives AB	Composition comprising ceftaroline and tobramycin
CA2753387C (en) *	2009-02-23	2017-01-24	Forest Laboratories Holdings Limited	Novel cephem compounds useful for the treatment of bacterial infections
MX2012003201A (es)	2009-09-21	2012-05-08	Astrazeneca Ab	Composiciones y metodos para tratar infecciones bacterianas utilizando ceftarolina.
FR2951171A1 (fr) *	2009-10-09	2011-04-15	Novexel	Nouveau sel de sodium d'un compose azabicyclique sous forme enantiomere cristallisee et nouvelles formes polymorphes et pseudopolymorphes ainsi que leur preparation
CN103649051B (zh)	2011-06-17	2016-04-13	阿斯利康(瑞典)有限公司	制备包括反-7-氧代-6-(磺基氧基)-1,6-二氮杂二环[3,2,1]辛烷-2-甲酰胺的杂环化合物及其盐的方法
EP2788361A1 (en)	2011-12-07	2014-10-15	Ranbaxy Laboratories Limited	Process for preparing ceftaroline salts or hydrates thereof
CN104718216B (zh) *	2012-10-19	2017-09-22	桑多斯股份公司	制备头孢洛林酯的新方法
CN102977124B (zh) *	2012-12-13	2014-11-26	山东诚创医药技术开发有限公司	7β-[(苯乙酰)氨基]-3-[4-(1-甲基-4-吡啶鎓)-2-噻唑硫基]-3-头孢烯-4-羧酸二苯甲基酯的制备方法
AU2013366718A1 (en) *	2012-12-20	2015-05-14	Sandoz Ag	Novel crystalline forms of ceftaroline fosamil
ES2900838T3 (es)	2014-02-21	2022-03-18	Shanghai Micurx Pharmaceutical Co Ltd	Profármacos de O-carbonil fosforamidato solubles en agua para administración terapéutica
CN106565784B (zh) *	2016-10-31	2019-02-26	瑞阳制药有限公司	头孢洛林酯二钠盐的纯化方法
CN110872322B (zh) *	2018-08-29	2022-08-02	上海博志研新药物技术有限公司	乙酸头孢罗膦一水合物及其中间体的制备方法
CN113072567B (zh) *	2021-03-26	2022-10-14	海南海灵化学制药有限公司	一种拉氧头孢钠合成工艺
CN113214323A (zh) *	2021-04-30	2021-08-06	瑞阳制药股份有限公司	分段式头孢罗膦高效稳定析晶方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5941999B2 (ja) *	1975-07-24	1984-10-11	武田薬品工業株式会社	セフエムまたはベナム化合物の製造法
US4268509A (en)	1978-07-10	1981-05-19	Fujisawa Pharmaceutical Co., Ltd.	New cephem compounds and processes for preparation thereof
JPS5511600A (en) *	1978-07-10	1980-01-26	Fujisawa Pharmaceut Co Ltd	Cephem compound, its salt, their preparation and remedy and prophylactic for microbism containing mainly the same
FR2511372A1 (fr)	1981-08-17	1983-02-18	Rhone Poulenc Sante	Nouveaux derives de la cephalosporine et leur preparation
JPS5931791A (ja) *	1982-07-19	1984-02-20	Fujisawa Pharmaceut Co Ltd	新規セフエム化合物およびその製造法、並びに細菌感染症予防・治療剤
US4563449A (en)	1982-07-19	1986-01-07	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
JPS62238291A (ja) *	1986-04-10	1987-10-19	Fujisawa Pharmaceut Co Ltd	セフエム化合物および医薬として許容されるその塩
US4978663A (en) *	1989-08-16	1990-12-18	Hoechst-Roussel Pharmaceuticals Inc.	5-(1-aminocyclohexyl)-2(1H)-pyridinone compounds which have pharmaceutical utility
JP3514495B2 (ja)	1992-10-02	2004-03-31	エーザイ株式会社	ハロゲン化アミノチアジアゾリル酢酸誘導体の製造法
JP3927262B2 (ja) *	1995-07-19	2007-06-06	武田薬品工業株式会社	セフェム化合物、その製造法および抗菌組成物
JPH10265488A (ja) *	1997-03-27	1998-10-06	Takeda Chem Ind Ltd	ホスフォノセフェム誘導体

1998
- 1998-12-02 TW TW087119933A patent/TW473479B/zh not_active IP Right Cessation
- 1998-12-17 WO PCT/JP1998/005709 patent/WO1999032497A1/ja active IP Right Grant
- 1998-12-17 EP EP09158866A patent/EP2080765A1/en not_active Withdrawn
- 1998-12-17 KR KR10-2000-7006796A patent/KR100384047B1/ko not_active IP Right Cessation
- 1998-12-17 CA CA002314564A patent/CA2314564C/en not_active Expired - Lifetime
- 1998-12-17 AT AT98961385T patent/ATE430155T1/de active
- 1998-12-17 JP JP35888798A patent/JP3467418B2/ja not_active Expired - Lifetime
- 1998-12-17 US US09/555,949 patent/US6417175B1/en not_active Expired - Lifetime
- 1998-12-17 CN CN2005100079635A patent/CN1679595B/zh not_active Expired - Lifetime
- 1998-12-17 AU AU16832/99A patent/AU1683299A/en not_active Abandoned
- 1998-12-17 EP EP98961385A patent/EP1043327B1/en not_active Expired - Lifetime
- 1998-12-17 DK DK98961385T patent/DK1043327T3/da active
- 1998-12-17 DE DE69840796T patent/DE69840796D1/de not_active Expired - Lifetime
- 1998-12-17 ES ES98961385T patent/ES2325139T3/es not_active Expired - Lifetime
- 1998-12-17 CN CNB988122944A patent/CN1194980C/zh not_active Expired - Lifetime
- 1998-12-17 PT PT98961385T patent/PT1043327E/pt unknown
2000
- 2000-07-04 JP JP2000206824A patent/JP2001048893A/ja active Pending
2009
- 2009-01-16 JP JP2009007750A patent/JP2009114202A/ja not_active Abandoned
- 2009-07-29 CY CY20091100809T patent/CY1109276T1/el unknown
2013
- 2013-01-07 CY CY2013003C patent/CY2013003I2/el unknown
- 2013-01-08 BE BE2013C004C patent/BE2013C004I2/fr unknown
- 2013-01-11 NL NL300568C patent/NL300568I1/nl unknown
- 2013-01-16 LU LU92134C patent/LU92134I2/fr unknown
- 2013-02-06 FR FR13C0008C patent/FR13C0008I2/fr active Active

Also Published As

Publication number	Publication date
EP1043327A4 (en)	2001-12-12
TW473479B (en)	2002-01-21
CY2013003I2 (el)	2015-08-05
CN1194980C (zh)	2005-03-30
EP2080765A1 (en)	2009-07-22
ES2325139T3 (es)	2009-08-26
EP1043327B1 (en)	2009-04-29
JP2009114202A (ja)	2009-05-28
KR100384047B1 (ko)	2003-05-14
JPH11255772A (ja)	1999-09-21
PT1043327E (pt)	2009-07-02
AU1683299A (en)	1999-07-12
LU92134I2 (fr)	2013-03-18
JP3467418B2 (ja)	2003-11-17
NL300568I2 (el)	2016-01-18
JP2001048893A (ja)	2001-02-20
EP1043327A1 (en)	2000-10-11
DK1043327T3 (da)	2009-08-17
KR20010015885A (ko)	2001-02-26
ATE430155T1 (de)	2009-05-15
CA2314564C (en)	2008-11-18
CN1679595A (zh)	2005-10-12
CY2013003I1 (el)	2014-07-02
US6417175B1 (en)	2002-07-09
WO1999032497A1 (fr)	1999-07-01
DE69840796D1 (de)	2009-06-10
CA2314564A1 (en)	1999-07-01
NL300568I1 (el)	2016-01-18
CN1679595B (zh)	2010-05-12
CN1282335A (zh)	2001-01-31
CY1109276T1 (el)	2014-07-02
FR13C0008I2 (fr)	2013-08-16
FR13C0008I1 (el)	2013-03-22

Publication	Publication Date	Title
BE2013C004I2 (en)	2018-01-29	Phosphonocephem derivatives, process for the preparation of the same, and use thereof
AU1463195A (en)	1995-08-15	Substituted aromatic compounds as c.amp phosphodiesterase- and tnf-inhibitors
IE892340L (en)	1990-01-20	4-oxoquinoline-3-carboxylic acid derivatives, their¹preparation and their use
AU3461697A (en)	1998-02-10	Heterocyclic compounds, their production and use
HUT70159A (en)	1995-09-28	Oxazolidinedion derivatives, pharmaceutical compositions containing them, their production and use
HUT54685A (en)	1991-03-28	Process for producing condensed heterocyclic compounds, salts and intermediates, and fungicide compositions containing them
AU8345491A (en)	1992-04-02	Heterocyclic derivatives
CA2219692A1 (en)	1998-04-30	S type 2-substituted hydroxy-2-indolidinylbutyric ester compounds and process for preparation thereof
AU2267495A (en)	1995-11-16	Benzamide derivatives as vasopressin antagonists
PL309874A1 (en)	1996-02-05	Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives
WO2006103342A8 (fr)	2007-12-21	Derives d'indanyl-piperazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO1994019343A3 (en)	1994-10-27	Novel use as anti-inflammatory agents for bis-heterocyclic compounds and pharmaceutical compositions thereof
IE901350L (en)	1990-10-14	Diaminoethylene compounds
AU582553B2 (en)	1989-04-06	11-substituted 5H,11H-pyrrolo``2,1-c````1,4``benzoxazepines, a process for their preparation and their use as medicaments
CA2334727A1 (en)	1999-12-16	Tetrahydroquinoline derivatives as glycine antagonists
IE891199L (en)	1989-10-18	2-alkyl-3-benzoylbenzofurans and pharmaceutical compositions¹containing them
CA2191874A1 (en)	1995-12-14	Novel processes and intermediates for the preparation of piperazine derivatives
AU2148595A (en)	1995-10-30	4,6-di-t-butyl-2,3-dihydrobenzothiophene derivative
AU671163B2 (en)	1996-08-15	Alkyl substituted heterocyclic compounds
ATE375343T1 (de)	2007-10-15	Neue beta-lactamverbindungen und verfahren zu deren herstellung
IE781467L (en)	1979-01-25	4"-ureido-oleandomycin derivatives
CA2093510A1 (en)	1992-05-01	Oxysulfonyl carbamates
IE891261L (en)	1989-10-20	Heterotetracyclic lactam derivatives
EP0402472A4 (en)	1991-01-30	Pyrrole derivatives and process for their preparation
AU5910690A (en)	1991-01-24	Method of treating diabetes mellitus