AU9678598A - Stabilization of envelope glycoprotein trimers by disulfide bonds introduced into a gp41 glycoprotein ectodomain - Google Patents

Stabilization of envelope glycoprotein trimers by disulfide bonds introduced into a gp41 glycoprotein ectodomain

Info

Publication number: AU9678598A
Authority: AU; Australia
Prior art keywords: glycoprotein; stabilization; disulfide bonds; trimers; ectodomain
Prior art date: 1997-10-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU96785/98A

Inventor

Michael Farzan

Joseph G Sodroski

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Dana Farber Cancer Institute Inc

Original Assignee

Dana Farber Cancer Institute Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-10-01

Filing date

1998-10-01

Publication date

1999-04-23

1998-10-01 Application filed by Dana Farber Cancer Institute Inc filed Critical Dana Farber Cancer Institute Inc

1999-04-23 Publication of AU9678598A publication Critical patent/AU9678598A/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
AIDS & HIV (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AU96785/98A 1997-10-01 1998-10-01 Stabilization of envelope glycoprotein trimers by disulfide bonds introduced into a gp41 glycoprotein ectodomain Abandoned AU9678598A (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US6081397P	1997-10-01	1997-10-01
US60060813		1997-10-01
US6080897P	1997-10-03	1997-10-03
US60060808		1997-10-03
PCT/US1998/020693 WO1999016883A2 (en)	1997-10-01	1998-10-01	STABILIZATION OF ENVELOPE GLYCOPROTEIN TRIMERS BY DISULFIDE BONDS INTRODUCED INTO A gp41 GLYCOPROTEIN ECTODOMAIN

Publications (1)

Publication Number	Publication Date
AU9678598A true AU9678598A (en)	1999-04-23

Family

ID=26740384

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU96785/98A Abandoned AU9678598A (en)	1997-10-01	1998-10-01	Stabilization of envelope glycoprotein trimers by disulfide bonds introduced into a gp41 glycoprotein ectodomain

Country Status (4)

Country	Link
EP (1)	EP1019511A2 (en)
AU (1)	AU9678598A (en)
CA (1)	CA2305341C (en)
WO (1)	WO1999016883A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2781676B1 (en)	1998-07-31	2004-04-02	Pasteur Merieux Serums Vacc	QUARTER OF HIV ENV GENE EXPRESSION PRODUCT
EP1214333A4 (en) *	1999-09-17	2005-01-19	Dana Farber Cancer Inst Inc	Stabilized soluble glycoprotein trimers
US7179468B1 (en)	2000-06-08	2007-02-20	Cornell Research Foundation, Inc.	Antigen for developing neutralizing antibodies to human immunodeficiency virus
WO2002056831A2 (en)	2000-12-27	2002-07-25	Dana-Farber Cancer Institute, Inc.	Immunogenic proteoliposomes, and uses thereof
CA2634992C (en)	2001-07-05	2012-10-16	Novartis Vaccines And Diagnostics, Inc.	Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
WO2005118886A2 (en) *	2004-06-01	2005-12-15	Merck & Co., Inc.	Stable peptide mimetic of hiv gp41 fusion intermediate
ES2324755B1 (en) *	2007-04-04	2010-05-31	Consejo Superior De Investigaciones Cientificas (Csic)	PROTEIN GP120 POLYPEPTIDE ABLE TO INHIBIT THE VITAL CYCLE OF AIDS VIRUS.
ATE538129T1 (en)	2007-09-07	2012-01-15	Complix N V	NON-NATURAL PROTEINOUS STRUCTURE COMPRISING THREE NON-COVALENTLY ASSOCIATE PEPTIDES
EP2161278B1 (en) *	2008-09-08	2012-05-23	Complix N.V.	Single-chain coiled coil scaffold
WO2016201007A1 (en)	2015-06-08	2016-12-15	New York University	Stabilized minimal coiled-coil mimetics
US11891422B2 (en)	2018-11-16	2024-02-06	New York University	NEMO coiled coil mimics and methods of using same
CN110184298B (en) *	2019-05-15	2023-05-16	武汉璟泓科技股份有限公司	HIV mutant type surface glycoprotein, nano antigen and preparation method thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4704694A (en)	1985-12-16	1987-11-03	Automation Intelligence, Inc.	Learned part system
US4976778A (en)	1988-03-08	1990-12-11	Scm Metal Products, Inc.	Infiltrated powder metal part and method for making same
CA2116107A1 (en)	1991-09-05	1993-03-18	George Y. Wu	Targeted delivery of poly-or oligonucleotides to cells
CA2183667A1 (en)	1994-02-22	1995-08-24	Wayne A. Marasco	Nucleic acid delivery system, method of synthesis and uses thereof

1998
- 1998-10-01 AU AU96785/98A patent/AU9678598A/en not_active Abandoned
- 1998-10-01 EP EP98950846A patent/EP1019511A2/en not_active Withdrawn
- 1998-10-01 CA CA002305341A patent/CA2305341C/en not_active Expired - Fee Related
- 1998-10-01 WO PCT/US1998/020693 patent/WO1999016883A2/en active Application Filing

Also Published As

Publication number	Publication date
CA2305341A1 (en)	1999-04-08
WO1999016883A3 (en)	1999-06-17
CA2305341C (en)	2009-01-06
WO1999016883A2 (en)	1999-04-08
EP1019511A2 (en)	2000-07-19

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Legal Events

Date	Code	Title	Description
2000-06-15	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase