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AU6869996A - Use of esters of polyhydric alcohols to enhance the oral bioavailability of drug substances as well as novel esters and pharmaceutical compositions containing them - Google Patents

Use of esters of polyhydric alcohols to enhance the oral bioavailability of drug substances as well as novel esters and pharmaceutical compositions containing them

Info

Publication number
AU6869996A
AU6869996A AU68699/96A AU6869996A AU6869996A AU 6869996 A AU6869996 A AU 6869996A AU 68699/96 A AU68699/96 A AU 68699/96A AU 6869996 A AU6869996 A AU 6869996A AU 6869996 A AU6869996 A AU 6869996A
Authority
AU
Australia
Prior art keywords
esters
enhance
well
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU68699/96A
Inventor
Morten Sloth Weidner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU6869996A publication Critical patent/AU6869996A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/12—Acetic acid esters
    • C07C69/18—Acetic acid esters of trihydroxylic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AU68699/96A 1995-09-13 1996-09-13 Use of esters of polyhydric alcohols to enhance the oral bioavailability of drug substances as well as novel esters and pharmaceutical compositions containing them Abandoned AU6869996A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK1018/95 1995-09-13
DK101895 1995-09-13
PCT/DK1996/000387 WO1997009978A1 (en) 1995-09-13 1996-09-13 Use of esters of polyhydric alcohols to enhance the oral bioavailability of drug substances as well as novel esters and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
AU6869996A true AU6869996A (en) 1997-04-01

Family

ID=8100075

Family Applications (1)

Application Number Title Priority Date Filing Date
AU68699/96A Abandoned AU6869996A (en) 1995-09-13 1996-09-13 Use of esters of polyhydric alcohols to enhance the oral bioavailability of drug substances as well as novel esters and pharmaceutical compositions containing them

Country Status (2)

Country Link
AU (1) AU6869996A (en)
WO (1) WO1997009978A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440980B1 (en) 1996-09-17 2002-08-27 Avanir Pharmaceuticals Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
EP0958828A1 (en) * 1998-05-22 1999-11-24 Greither, Peter Artichoke containing preparation especially for use as medicaments or nutritional supplement
ITMI981528A1 (en) * 1998-07-03 2000-01-03 Recordati Ind Chimica E Farma TOPICAL FORMULATIONS OF ACICLOVIR
US9011908B2 (en) 2009-04-06 2015-04-21 Banner Life Sciences Llc Progesterone solutions for increased bioavailability

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB808634A (en) * 1955-06-29 1959-02-11 Eastman Kodak Co Preparation of mixed glycerol ester compositions
GB1157753A (en) * 1966-06-24 1969-07-09 Bp Chem Int Ltd Improvements in or relating to Synthetic Lubricants
JPS53107408A (en) * 1977-02-28 1978-09-19 Yamanouchi Pharmaceut Co Ltd Micellar preparation for rectal infusion
DE3830494B4 (en) * 1987-09-15 2006-05-18 Novartis Ag Water-soluble monoesters as solubilizers for pharmacologically active substances and pharmaceutical excipients
DK657689D0 (en) * 1989-12-22 1989-12-22 Novo Nordisk As MEDICINE WITH BIOLOGICAL EFFECT ON THE GAS MILK
WO1993011798A1 (en) * 1991-12-16 1993-06-24 Alza Corporation Improved formulations with hydrophobic permeation enhancers

Also Published As

Publication number Publication date
WO1997009978A1 (en) 1997-03-20

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