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AU6242294A - 3,3-disubstituted tri- and tetracyclic indolin-2-ones useful for the treatment of cognitive disorders - Google Patents

3,3-disubstituted tri- and tetracyclic indolin-2-ones useful for the treatment of cognitive disorders

Info

Publication number
AU6242294A
AU6242294A AU62422/94A AU6242294A AU6242294A AU 6242294 A AU6242294 A AU 6242294A AU 62422/94 A AU62422/94 A AU 62422/94A AU 6242294 A AU6242294 A AU 6242294A AU 6242294 A AU6242294 A AU 6242294A
Authority
AU
Australia
Prior art keywords
indolin
tetracyclic
disubstituted
tri
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU62422/94A
Inventor
Richard Alan Earl
Melvyn John Myers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Pharma Co
Original Assignee
DuPont Merck Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DuPont Merck Pharmaceutical Co filed Critical DuPont Merck Pharmaceutical Co
Publication of AU6242294A publication Critical patent/AU6242294A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06Peri-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU62422/94A 1992-10-13 1993-10-12 3,3-disubstituted tri- and tetracyclic indolin-2-ones useful for the treatment of cognitive disorders Abandoned AU6242294A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96052292A 1992-10-13 1992-10-13
US960522 1992-10-13
PCT/US1993/009476 WO1994009009A1 (en) 1992-10-13 1993-10-12 3,3-disubstituted tri- and tetracyclic indolin-2-ones useful for the treatment of cognitive disorders

Publications (1)

Publication Number Publication Date
AU6242294A true AU6242294A (en) 1994-05-09

Family

ID=25503278

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62422/94A Abandoned AU6242294A (en) 1992-10-13 1993-10-12 3,3-disubstituted tri- and tetracyclic indolin-2-ones useful for the treatment of cognitive disorders

Country Status (8)

Country Link
EP (1) EP0664810A1 (en)
JP (1) JPH08502293A (en)
AU (1) AU6242294A (en)
CA (1) CA2146000A1 (en)
IL (1) IL107251A0 (en)
MX (1) MX9306337A (en)
WO (1) WO1994009009A1 (en)
ZA (1) ZA937604B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112624972A (en) * 2019-09-24 2021-04-09 中国人民解放军军事科学院军事医学研究院 Acridone compound and medical application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5173489A (en) * 1986-04-10 1992-12-22 The Dupont Merck Pharmaceutical Co. α,α-disubstituted aromatics and heteroaromatics as cognition enhancers
US4760083A (en) * 1986-04-10 1988-07-26 E. I. Dupont De Nemours & Company 3,3-disubstituted indolines
US5278045A (en) * 1990-02-28 1994-01-11 Du Pont Merck Pharmaceutical Company Method and compositions to screen compounds for enhancement of the cholinergic, dopaminergic and serotonergic function

Also Published As

Publication number Publication date
WO1994009009A1 (en) 1994-04-28
IL107251A0 (en) 1994-01-25
EP0664810A1 (en) 1995-08-02
JPH08502293A (en) 1996-03-12
MX9306337A (en) 1995-01-31
CA2146000A1 (en) 1994-04-28
ZA937604B (en) 1995-04-13

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