US9096636B2
(en)
|
1996-06-06 |
2015-08-04 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
US8273866B2
(en)
|
2002-02-20 |
2012-09-25 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA)
|
US7833992B2
(en)
|
2001-05-18 |
2010-11-16 |
Merck Sharpe & Dohme |
Conjugates and compositions for cellular delivery
|
US20070026394A1
(en)
|
2000-02-11 |
2007-02-01 |
Lawrence Blatt |
Modulation of gene expression associated with inflammation proliferation and neurite outgrowth using nucleic acid based technologies
|
US7491805B2
(en)
|
2001-05-18 |
2009-02-17 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
WO2003070918A2
(en)
*
|
2002-02-20 |
2003-08-28 |
Ribozyme Pharmaceuticals, Incorporated |
Rna interference by modified short interfering nucleic acid
|
US8202979B2
(en)
|
2002-02-20 |
2012-06-19 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
|
US7198924B2
(en)
|
2000-12-11 |
2007-04-03 |
Invitrogen Corporation |
Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
|
AU2001297906B2
(en)
*
|
2000-10-31 |
2007-07-19 |
Commonwealth Scientific And Industrial Research Organisation |
Method and means for producing barley yellow dwarf virus resistant cereal plants
|
CA2429397C
(en)
|
2001-01-26 |
2014-06-03 |
Commonwealth Scientific And Industrial Research Organisation |
Methods and means for producing efficient silencing construct using recombinational cloning
|
US9994853B2
(en)
|
2001-05-18 |
2018-06-12 |
Sirna Therapeutics, Inc. |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
|
US20050148530A1
(en)
|
2002-02-20 |
2005-07-07 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US7109165B2
(en)
|
2001-05-18 |
2006-09-19 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
DE10133858A1
(en)
|
2001-07-12 |
2003-02-06 |
Aventis Pharma Gmbh |
Synthetic double-stranded oligonucleotides for targeted inhibition of gene expression
|
KR20040022449A
(en)
|
2001-07-12 |
2004-03-12 |
유니버시티 오브 매사추세츠 |
IN VIVO PRODUCTION OF SMALL INTERFERING RNAs THAT MEDIATE GENE SILENCING
|
US8022272B2
(en)
|
2001-07-13 |
2011-09-20 |
Sungene Gmbh & Co. Kgaa |
Expression cassettes for transgenic expression of nucleic acids
|
US20030198627A1
(en)
*
|
2001-09-01 |
2003-10-23 |
Gert-Jan Arts |
siRNA knockout assay method and constructs
|
US7456335B2
(en)
|
2001-09-03 |
2008-11-25 |
Basf Plant Science Gmbh |
Nucleic acid sequences and their use in methods for achieving pathogen resistance in plants
|
US7230168B2
(en)
|
2001-12-20 |
2007-06-12 |
The Curators Of The University Of Missouri |
Reversible male sterility in transgenic plants by expression of cytokinin oxidase
|
US9181551B2
(en)
|
2002-02-20 |
2015-11-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
US9657294B2
(en)
|
2002-02-20 |
2017-05-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
US8013143B2
(en)
|
2002-02-20 |
2011-09-06 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA)
|
EP1432724A4
(en)
*
|
2002-02-20 |
2006-02-01 |
Sirna Therapeutics Inc |
Rna interference mediated inhibition of map kinase genes
|
US7928220B2
(en)
|
2002-02-20 |
2011-04-19 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of stromal cell-derived factor-1 (SDF-1) gene expression using short interfering nucleic acid (siNA)
|
CA2478904A1
(en)
*
|
2002-03-14 |
2003-09-18 |
Commonwealth Scientific And Industrial Research Organisation |
Modified gene-silencing rna and uses thereof
|
US20040180438A1
(en)
|
2002-04-26 |
2004-09-16 |
Pachuk Catherine J. |
Methods and compositions for silencing genes without inducing toxicity
|
US7399586B2
(en)
|
2002-05-23 |
2008-07-15 |
Ceptyr, Inc. |
Modulation of biological signal transduction by RNA interference
|
ATE405658T1
(en)
|
2002-07-26 |
2008-09-15 |
Basf Plant Science Gmbh |
NEW SELECTION PROCEDURES
|
EP1540004A4
(en)
*
|
2002-07-31 |
2007-10-03 |
Nucleonics Inc |
Double stranded rna structures and constructs, and methods for generating and using the same
|
EP2278018A3
(en)
|
2002-08-07 |
2012-01-04 |
BASF Plant Science GmbH |
Nucleic acid sequences encoding proteins associated with abiotic stress response
|
US7923547B2
(en)
|
2002-09-05 |
2011-04-12 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
US7696345B2
(en)
|
2002-11-05 |
2010-04-13 |
Isis Pharmaceuticals, Inc. |
Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation
|
AU2003295387A1
(en)
|
2002-11-05 |
2004-06-03 |
Isis Parmaceuticals, Inc. |
Modified oligonucleotides for use in rna interference
|
US9150606B2
(en)
|
2002-11-05 |
2015-10-06 |
Isis Pharmaceuticals, Inc. |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
|
US9150605B2
(en)
|
2002-11-05 |
2015-10-06 |
Isis Pharmaceuticals, Inc. |
Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
|
CA2504720C
(en)
|
2002-11-05 |
2013-12-24 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
WO2005014828A2
(en)
|
2003-08-01 |
2005-02-17 |
Basf Plant Science Gmbh |
Process for the production of fine chemicals in plants
|
WO2006032707A2
(en)
|
2004-09-24 |
2006-03-30 |
Basf Plant Science Gmbh |
Plant cells and plants with increased tolerance to environmental stress
|
WO2005002507A2
(en)
|
2003-06-03 |
2005-01-13 |
Isis Pharmaceuticals, Inc. |
Modulation of survivin expression
|
IL157538A0
(en)
|
2003-08-21 |
2004-03-28 |
Bar Ilan Res & Dev Company Ltd |
Plant resistant to cytoplasm-feeding parasites
|
WO2005054438A2
(en)
|
2003-12-01 |
2005-06-16 |
Invitrogen Corporation |
Nucleic acid molecules containing recombination sites and methods of using the same
|
US7858769B2
(en)
|
2004-02-10 |
2010-12-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using multifunctional short interfering nucleic acid (multifunctional siNA)
|
US10508277B2
(en)
|
2004-05-24 |
2019-12-17 |
Sirna Therapeutics, Inc. |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
|
US8394947B2
(en)
|
2004-06-03 |
2013-03-12 |
Isis Pharmaceuticals, Inc. |
Positionally modified siRNA constructs
|
AU2005321630A1
(en)
|
2004-07-02 |
2006-07-06 |
Metanomics Gmbh |
Process for the production of fine chemicals
|
EP2166103B1
(en)
|
2004-08-02 |
2013-05-22 |
BASF Plant Science GmbH |
Method for isolation of transcription termination sequences
|
US7884086B2
(en)
|
2004-09-08 |
2011-02-08 |
Isis Pharmaceuticals, Inc. |
Conjugates for use in hepatocyte free uptake assays
|
EP2166098B1
(en)
|
2004-10-05 |
2013-11-06 |
SunGene GmbH |
Constitutive expression cassettes for regulation of plant expression
|
EP1655364A3
(en)
|
2004-11-05 |
2006-08-02 |
BASF Plant Science GmbH |
Expression cassettes for seed-preferential expression in plants
|
EP2163631B1
(en)
|
2004-11-25 |
2013-05-22 |
SunGene GmbH |
Expression cassettes for guard cell-preferential expression in plants
|
EP1666599A3
(en)
|
2004-12-04 |
2006-07-12 |
SunGene GmbH |
Expression cassettes for mesophyll- and/or epidermis-preferential expression in plants
|
EP2072620B1
(en)
|
2004-12-08 |
2013-05-08 |
SunGene GmbH |
Expression casstettes for vascular tissue-preferential expression in plants
|
EP1669456A3
(en)
|
2004-12-11 |
2006-07-12 |
SunGene GmbH |
Expression cassettes for meristem-preferential expression in plants
|
EP1974049A2
(en)
|
2004-12-17 |
2008-10-01 |
Metanomics GmbH |
Process for the control of production of fine chemicals
|
WO2006071219A1
(en)
|
2004-12-28 |
2006-07-06 |
Pioneer Hi-Bred International, Inc. |
Improved grain quality through altered expression of seed proteins
|
EP2186903A3
(en)
|
2005-02-09 |
2010-09-08 |
BASF Plant Science GmbH |
Expression cassettes for regulation of expression in monocotyledonous plants
|
EP1851317B1
(en)
|
2005-02-23 |
2011-10-26 |
North Carolina State University |
Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes
|
WO2006089950A2
(en)
|
2005-02-26 |
2006-08-31 |
Basf Plant Science Gmbh |
Expression cassettes for seed-preferential expression in plants
|
CN101137752B
(en)
|
2005-03-08 |
2013-04-03 |
巴斯福植物科学有限公司 |
Expression enhancing intron sequences
|
EP1882037A2
(en)
|
2005-05-10 |
2008-01-30 |
BASF Plant Science GmbH |
Expression cassettes for seed-preferential expression in plants
|
NZ564016A
(en)
|
2005-05-25 |
2009-08-28 |
Pioneer Hi Bred Int |
Methods for improving crop plant architecture and yield by introducing recombinant expression cassette
|
DE602006019588D1
(en)
|
2005-06-23 |
2011-02-24 |
Basf Plant Science Gmbh |
IMPROVED METHODS FOR PRODUCING STABILIZED TRANSFORMED AND FRUITFUL BUNTMAIS PLANTS
|
CN101268194A
(en)
|
2005-09-20 |
2008-09-17 |
巴斯福植物科学有限公司 |
Methods for controlling gene expression using ta-siRNA
|
CA2628505A1
(en)
|
2005-11-08 |
2007-05-18 |
Basf Plant Science Gmbh |
Use of armadillo repeat (arm1) polynucleotides for obtaining resistance to pathogens in plants
|
EP2380986A1
(en)
|
2006-01-12 |
2011-10-26 |
BASF Plant Science GmbH |
Use of stomatin (STM1) polynucleotides for achieving a pathogen resistance in plants
|
CA2637252A1
(en)
|
2006-01-17 |
2007-07-26 |
Biolex Therapeutics, Inc. |
Plants and plant cells having inhibited expression of .alpha.1,3-fucosyltransferase and .beta.1,2-xylosyltransferase
|
EP1991568A2
(en)
|
2006-02-09 |
2008-11-19 |
Pioneer Hi-Bred International Inc. |
Genes for enhancing nitrogen utilization efficiency in crop plants
|
CA2644273A1
(en)
|
2006-04-05 |
2008-03-27 |
Metanomics Gmbh |
Process for the production of a fine chemical
|
MX2008013354A
(en)
|
2006-04-19 |
2008-11-10 |
Pioneer Hi Bred Int |
Isolated polynucleotide molecules corresponding to mutant and wild-type alleles of the maize d9 gene and methods of use.
|
US8592652B2
(en)
|
2007-01-15 |
2013-11-26 |
Basf Plant Science Gmbh |
Use of subtilisin-like RNR9 polynucleotide for achieving pathogen resistance in plants
|
CA2675926A1
(en)
|
2007-02-16 |
2008-08-21 |
Basf Plant Science Gmbh |
Nucleic acid sequences for regulation of embryo-specific expression in monocotyledonous plants
|
AU2008252998A1
(en)
|
2007-05-22 |
2008-11-27 |
Basf Plant Science Gmbh |
Plant cells and plants with increased tolerance and/or resistance to environmental stress and increased biomass production-KO
|
US20100240597A1
(en)
|
2007-06-15 |
2010-09-23 |
Arkansas State University |
Methods of delivery of molecules to cells using a ricin subunit and compositions relating to same
|
ES2651911T3
(en)
|
2007-08-14 |
2018-01-30 |
Commonwealth Scientific And Industrial Research Organisation |
Improved methods of gene silencing
|
EP2231168A4
(en)
|
2007-10-03 |
2012-01-04 |
Quark Pharmaceuticals Inc |
Novel sirna structures
|
WO2009064771A2
(en)
|
2007-11-12 |
2009-05-22 |
North Carolina State University |
Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes
|
CL2008003469A1
(en)
|
2007-11-20 |
2009-09-04 |
Pioneer Hi Bred Int |
Nucleic acid isolated from corn associated with ethylene signaling in plants; expression cassette; host cell; encoded protein; and method of modulation of the ethylene response in a plant.
|
AU2008340002A1
(en)
|
2007-12-21 |
2009-07-02 |
Basf Plant Science Gmbh |
Plants with increased yield (KO NUE)
|
WO2009147684A2
(en)
|
2008-06-06 |
2009-12-10 |
Quark Pharmaceuticals, Inc. |
Compositions and methods for treatment of ear disorders
|
MX2011003616A
(en)
|
2008-10-30 |
2011-08-15 |
Pioneer Hi Bred Int |
Manipulation of glutamine synthetases (gs) to improve nitrogen use efficiency and grain yield in higher plants.
|
WO2010065867A1
(en)
|
2008-12-04 |
2010-06-10 |
Pioneer Hi-Bred International, Inc. |
Methods and compositions for enhanced yield by targeted expression of knotted1
|
US20110288155A1
(en)
|
2008-12-18 |
2011-11-24 |
Elena Feinstein |
Sirna compounds and methods of use thereof
|
WO2010101818A1
(en)
|
2009-03-02 |
2010-09-10 |
Pioneer Hi-Bred International, Inc. |
Nac transcriptional activators involved in abiotic stress tolerance
|
US8987553B2
(en)
|
2009-04-14 |
2015-03-24 |
Pioneer Hi Bred International Inc |
Modulation of ACC synthase improves plant yield under low nitrogen conditions
|
EP2421976B1
(en)
|
2009-04-22 |
2015-09-16 |
BASF Plant Science Company GmbH |
Whole seed specific promoter
|
CA2766858A1
(en)
|
2009-07-10 |
2011-01-13 |
Basf Plant Science Company Gmbh |
Expression cassettes for endosperm-specific expression in plants
|
WO2011011273A1
(en)
|
2009-07-24 |
2011-01-27 |
Pioneer Hi-Bred International, Inc. |
The use of dimerization domain component stacks to modulate plant architecture
|
AR078502A1
(en)
|
2009-10-02 |
2011-11-09 |
Pioneer Hi Bred Int |
REGULATION DOWN ACC (1-AMINOCICLOPROPANO-1-CARBOXILIC ACID) SYNTHEASE FOR IMPROVED PLANTS PERFORMANCE
|
US8796239B2
(en)
|
2009-11-26 |
2014-08-05 |
Quark Pharmaceuticals, Inc. |
Sirna compounds comprising terminal substitutions
|
BR112012013156A2
(en)
|
2009-12-03 |
2017-06-13 |
Basf Plant Science Co Gmbh |
expression cassette, vector, host cell, transgenic plant tissue and method for producing a transgenic plant tissue
|
EP2862929B1
(en)
|
2009-12-09 |
2017-09-06 |
Quark Pharmaceuticals, Inc. |
Compositions and methods for treating diseases, disorders or injury of the CNS
|
US20110167517A1
(en)
|
2010-01-06 |
2011-07-07 |
Pioneer Hi-Bred International, Inc. |
Identification of diurnal rhythms in photosynthetic and non-photsynthetic tissues from zea mays and use in improving crop plants
|
WO2011084193A1
(en)
|
2010-01-07 |
2011-07-14 |
Quark Pharmaceuticals, Inc. |
Oligonucleotide compounds comprising non-nucleotide overhangs
|
ES2817780T3
(en)
|
2010-07-12 |
2021-04-08 |
The State Of Israel Ministry Of Agriculture And Rural Development Agricultural Res Organization A R |
Isolated polynucleotides and methods and plants that use them to regulate the acidity of plants
|
ES2663009T3
(en)
|
2010-10-29 |
2018-04-10 |
Sirna Therapeutics, Inc. |
Inhibition of RNA-mediated gene expression using short interference nucleic acids (ANic)
|
EP2681315B1
(en)
|
2011-03-03 |
2017-05-03 |
Quark Pharmaceuticals, Inc. |
Oligonucleotide modulators of the toll-like receptor pathway
|
US9796979B2
(en)
|
2011-03-03 |
2017-10-24 |
Quark Pharmaceuticals Inc. |
Oligonucleotide modulators of the toll-like receptor pathway
|
CA2831144A1
(en)
|
2011-03-23 |
2012-09-27 |
Pioneer Hi-Bred International, Inc. |
Methods for producing a complex transgenic trait locus
|
CA2833876A1
(en)
|
2011-04-29 |
2012-11-01 |
Pioneer Hi-Bred International, Inc. |
Down-regulation of a homeodomain-leucine zipper i-class homeobox gene for improved plant performance
|
EP2721160A2
(en)
|
2011-06-14 |
2014-04-23 |
Synthon Biopharmaceuticals B.V. |
Compositions and methods for making and biocontaining auxotrophic transgenic plants
|
MX2013015174A
(en)
|
2011-06-21 |
2014-09-22 |
Pioneer Hi Bred Int |
Methods and compositions for producing male sterile plants.
|
RU2014121387A
(en)
*
|
2011-10-28 |
2015-12-10 |
Е.И. Дюпон Де Немур Энд Компани |
METHODS AND COMPOSITIONS FOR GENE SILENCING USING ARTIFICIAL MICRORNAKS
|
CA2853775A1
(en)
|
2011-10-31 |
2013-05-10 |
Pioneer Hi-Bred International, Inc. |
Improving plant drought tolerance, nitrogen use efficiency and yield
|
WO2013070821A1
(en)
|
2011-11-08 |
2013-05-16 |
Quark Pharmaceuticals, Inc. |
Methods and compositions for treating diseases, disorders or injury of the nervous system
|
UA116097C2
(en)
|
2011-12-11 |
2018-02-12 |
Зе Стейт Оф Ізраел, Міністрі Оф Агрікалче Енд Руерал Девелопмент, Агрікалчерал Рісьоч Організейшн, (А.Р.О.), Волкані Сентре |
Methods of modulating stomata conductance and plant expression constructs for executing same
|
WO2013138309A1
(en)
|
2012-03-13 |
2013-09-19 |
Pioneer Hi-Bred International, Inc. |
Genetic reduction of male fertility in plants
|
WO2013138358A1
(en)
|
2012-03-13 |
2013-09-19 |
Pioneer Hi-Bred International, Inc. |
Genetic reduction of male fertility in plants
|
WO2014027021A1
(en)
|
2012-08-16 |
2014-02-20 |
Vib Vzw |
Means and methods for altering the lignin pathway in plants
|
EP2951298A1
(en)
|
2013-01-29 |
2015-12-09 |
The University Court of The University Of Glasgow |
Methods and means for increasing stress tolerance and biomass in plants
|
WO2014164014A1
(en)
|
2013-03-11 |
2014-10-09 |
Pioneer Hi-Bred International, Inc. |
Genes for improving nutrient uptake and abiotic stress tolerance in plants
|
US20160010101A1
(en)
|
2013-03-13 |
2016-01-14 |
Pioneer Hi-Bred International, Inc. |
Enhanced nitrate uptake and nitrate translocation by over- expressing maize functional low-affinity nitrate transporters in transgenic maize
|
US20160017360A1
(en)
|
2013-03-13 |
2016-01-21 |
Pioneer Hi-Bred International, Inc. |
Functional expression of bacterial major facilitator superfamily mfs gene in maize to improve agronomic traits and grain yield
|
US20160024513A1
(en)
|
2013-03-14 |
2016-01-28 |
Pioneer Hi-Bred International Inc. |
Maize stress related transcription factor 18 and uses thereof
|
US20140283216A1
(en)
|
2013-03-15 |
2014-09-18 |
Pioneer Hi Bred International Inc |
Compositions and methods of use of acc oxidase polynucleotides and polypeptides
|
WO2014147249A1
(en)
|
2013-03-21 |
2014-09-25 |
Vib Vzw |
Means and methods for the reduction of photorespiration in crops
|
CA2911185C
(en)
|
2013-06-11 |
2023-09-05 |
Syngenta Participations Ag |
Methods for generating transgenic plants
|
US20170166920A1
(en)
|
2014-01-30 |
2017-06-15 |
Two Blades Foundation |
Plants with enhanced resistance to phytophthora
|
WO2015171603A1
(en)
|
2014-05-06 |
2015-11-12 |
Two Blades Foundation |
Methods for producing plants with enhanced resistance to oomycete pathogens
|
WO2016005449A1
(en)
|
2014-07-08 |
2016-01-14 |
Vib Vzw |
Means and methods to increase plant yield
|
WO2017062790A1
(en)
|
2015-10-09 |
2017-04-13 |
Two Blades Foundation |
Cold shock protein receptors and methods of use
|
AU2017234920B2
(en)
|
2016-03-18 |
2023-08-17 |
E. I. Du Pont De Nemours And Company |
Methods and compositions for producing clonal, non-reduced, non-recombined gametes
|
CA3148950A1
(en)
|
2019-07-30 |
2021-02-04 |
The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (A.R.O.), Volcani Center |
Methods of controlling cannabinoid synthesis in plants or cells and plants and cells produced thereby
|
AU2022324708A1
(en)
|
2021-08-06 |
2024-02-15 |
Kws Vegetables B.V. |
Durable downy mildew resistance in spinach
|