AU2003211731A1 - Fixed length anchor and pull mitral valve device and method - Google Patents
Fixed length anchor and pull mitral valve device and methodInfo
- Publication number
- AU2003211731A1 AU2003211731A1 AU2003211731A AU2003211731A AU2003211731A1 AU 2003211731 A1 AU2003211731 A1 AU 2003211731A1 AU 2003211731 A AU2003211731 A AU 2003211731A AU 2003211731 A AU2003211731 A AU 2003211731A AU 2003211731 A1 AU2003211731 A1 AU 2003211731A1
- Authority
- AU
- Australia
- Prior art keywords
- anchor
- mitral valve
- heart
- coronary sinus
- valve annulus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Description
FIXED LENGTH ANCHOR AND PULL MITRAL VALVE DEVICE AND METHOD
Field of the Invention :
[1] The present invention generally relates to a device and method for treating dilated cardiomyopathy of a heart. The present invention more particularly relates to a device and method for reshaping the mitral valve annulus.
Background of the Invention : [2] The human heart generally includes four valves. Of these valves, a most critical one is known as the mitral valve. The mitral valve is located in the left atrial ventricular opening between the left atrium and left ventricle. The mitral valve is intended to prevent regurgitation of blood from the left ventricle into the left atrium when the left ventricle contracts. In preventing blood regurgitation the mitral valve must be able to withstand considerable back pressure as the left ventricle contracts. [3] The valve cusps of the mitral valve are anchored to muscular wall of the heart by delicate but strong fibrous cords in order to support the cusps during left ventricular contraction. In a healthy mitral valve, the geometry of the mitral valve ensures that the cusps overlie each other to preclude regurgitation of the blood during left ventricular contraction.
[4] The normal functioning of the mitral valve in preventing regurgitation can be impaired by dilated cardiomyopathy caused by disease or certain natural defects. For example, certain diseases may cause dilation of the mitral valve annulus. This can result in deformation of the mitral valve geometry to cause ineffective closure of the mitral valve during left ventricular contraction. Such ineffective closure results in leakage through the mitral valve and regurgitation.
Diseases such as bacterial inflammations of the heart or heart failure can cause the aforementioned distortion or dilation of the mitral valve annulus. Needless to say, mitral valve regurgitation must not go uncorrected. [5] One method of repairing a mitral valve having impaired function is to completely replace the valve. This method has been found to be particularly suitable for replacing a mitral valve when one of the cusps has been severely damaged or deformed. While the replacement of the entire valve eliminates the immediate problem associated with a dilated mitral valve annulus, presently available prosthetic heart valves do not possess the same durability as natural heart valves. [6] Various other surgical procedures have been developed to correct the deformation of the mitral valve annulus and thus retain the intact natural heart valve function. These surgical techniques involve repairing the shape of the dilated or deformed valve annulus. Such techniques, generally known as annuloplasty, require surgically restricting the valve annulus to minimize dilation. Here, a prosthesis is typically sutured about the base of the valve leaflets to reshape the valve annulus and restrict the movement of the valve annulus during the opening and closing of the mitral valve.
[7] Many different types of prostheses have been developed for use in such surgery. In general, prostheses are annular or partially annular shaped members which fit about the base of the valve annulus . The annular or partially annular shaped members may be formed from a rigid material, such as a metal, or from a flexible material. [8] While the prior art methods mentioned above have been able to achieve some success in treating mitral regurgitation, they have not been without problems and potential adverse consequences. For example, these procedures require open heart surgery. Such procedures are expensive, are extremely invasive
requiring considerable recovery time, and pose the concomitant mortality risks associated with such procedures. Moreover, such open heart procedures are particularly stressful on patients with a comprised cardiac condition. Given these factors, such procedures are often reserved as a last resort and hence are employed late in the mitral regurgitation progression. Further, the effectiveness of such procedures is difficult to assess during the procedure and may not be known until a much later time. Hence, the ability to make adjustments to or changes in the prostheses to obtain optimum effectiveness is extremely limited. Later corrections, if made at all, require still another open heart surgery.
[9] An improved therapy to treat mitral regurgitation without resorting to open heart surgery has recently been proposed. This is rendered possible by the realization that the coronary sinus of a heart is near to and at least partially encircles the mitral valve annulus and then extends into a venous system including the great cardiac vein. As used herein, the term "coronary sinus" is meant to refer to not only the coronary sinus itself but in addition, the venous system associated with the coronary sinus including the great cardiac vein. The therapy contemplates the use of a device introduced into the coronary sinus to reshape and advantageously effect the geometry of the mitral valve annulus. [10] The device includes a resilient member having a cross sectional dimension for being received within the coronary sinus of the heart and a longitudinal dimension having an unstressed arched configuration when placed in the coronary sinus. The device partially encircles and exerts an inward pressure on the mitral valve. The inward pressure constricts the mitral valve annulus, or at least a portion of it, to essentially restore the mitral valve geometry. This promotes effective valve sealing action and eliminates mitral regurgitation.
[11] The device may be implanted in the coronary sinus using only percutaneous techniques similar to the techniques used to implant cardiac leads such as pacemaker leads. One proposed system for implanting the device includes an elongated introducer configured for being releasably coupled to the device. The introducer is preferably flexible to permit it to advance the device into the heart and into the coronary sinus through the coronary sinus ostium. To promote guidance, an elongated sheath is first advanced into the coronary sinus. Then, the device and introducer are moved through a lumen of the sheath until the device is in position within the coronary sinus. Because the device is formed of resilient material, it conforms to the curvatures of the lumen as it is advanced through the sheath. The sheath is then partially retracted to permit the device to assume its unstressed arched configuration. Once the device is properly positioned, the introducer is then decoupled from the device and retracted through the sheath. The procedure is then completed by the retraction of the sheath. As a result, the device is left within the coronary sinus to exert the inward pressure on the mitral valve to restore mitral valve geometry.
[12] The foregoing therapy has many advantages over the traditional open heart surgery approach. Since the device, system and method may be employed in a comparatively noninvasive procedure, mitral valve regurgitation may be treated at an early stage in the mitral regurgitation progression. Further, the device may be placed with relative ease by any minimally invasive cardiologist. Still further, since the heart remains completely intact throughout the procedure, the effectiveness of the procedure may be readily determined. Moreover, should adjustments be deemed desirable, such adjustments may be made during the procedure and before the patient is sent to recovery.
[13] Another approach to treat mitral regurgitation with a device in the coronary sinus is based upon the observation that the application of a localized force against a discrete portion of the mitral valve annulus can terminate mitral regurgitation. This suggests that mitral valve dilation may be localized and nonuniform. Hence, the device applies a force to one or more discrete portions of the atrial wall of the coronary sinus to provide localized mitral valve annulus reshaping instead of generalized reshaping of the mitral valve annulus. Such localized therapy would have all the benefits of the generalized therapy. In addition, a localized therapy device may be easier to implant and adjust.
[14] A still further approach to treat mitral regurgitation from the coronary sinus of the heart contemplates a device having a first anchor configured to be positioned within and fixed to the coronary sinus of the heart adjacent the mitral valve annulus within the heart, a cable fixed to the first anchor and extending proximally from the first anchor within the heart, a second anchor configured to be positioned in and fixed in the heart proximal to the first anchor and arranged to slidingly receive the cable, and a lock that locks the cable on the second anchor. When the first and second anchors are fixed within the heart, the cable may be drawn proximally and locked on the second anchor. The geometry of the mitral valve is thereby effected. This approach provides flexibility in that the second anchor may be positioned and fixed in the coronary sinus or alternatively, the second anchor may be positioned and fixed in the right atrium. This approach further allows adjustments in the cable tension after implant. The present invention provides a still further alternative for treating mitral regurgitation with a device placed in the coronary sinus adjacent to the mitral valve annulus.
SUMMARY OF THE INVENTION [15] The present invention provides a device that effects mitral valve annulus geometry of a heart. The device includes a first anchor configured to be positioned within and anchored to the coronary sinus of the heart adjacent the mitral valve annulus within the heart, and a second anchor configured to be positioned within the heart proximal to the first anchor and adjacent the mitral valve annulus within the heart. The device further includes a connecting member having a fixed length permanently attached to the first and second anchors. As a result, when the first and second anchors are within the heart with the first anchor anchored in the coronary sinus, the second anchor may be displaced proximally to effect the geometry of the mitral valve annulus and released to maintain the effect on the' mitral valve geometry. The second anchor may be configured, when deployed, to anchor against distal movement but be moveable proximally to permit the second anchor to be displaced proximally within the coronary sinus. [16] The first anchor and the second anchor are preferably self-deploying upon release in the coronary sinus or may be deployable after placement. Further, the connecting member, in being of fixed length, has a maximum extended length and as such may be a rigid member, have an initial arcuate configuration, include a spring, having a maximum length or be flexible but not stretchable.
[17] The present invention further provides a device for effecting mitral valve annulus geometry of a heart. The device includes first anchor means for anchoring in the coronary sinus of the heart adjacent the mitral valve annulus, and second anchor means for being deployed within the heart proximal to the first anchor means and adjacent the mitral valve annulus, and connecting means having a fixed length and permanently connecting the first anchor means to the second anchor means.
As a result, when the first and second anchor means are within the heart with the first anchor means anchored in the coronary sinus, the second anchor means may be displaced proximally for cooperating with the first anchor means and the connecting means for effecting the geometry of the mitral valve annulus and released for maintaining the effect on the mitral valve geometry.
[18] The invention further provides a system that effects mitral valve annulus geometry of a heart. The system includes a mitral valve device including a first anchor configured to be positioned within and anchored to the coronary sinus of the heart adjacent the mitral valve annulus within the heart, a second anchor configured to be positioned within the heart proximal to the first anchor and adjacent the mitral valve annulus within the heart, and a connecting member having a fixed length permanently attached to the first and second anchors. [19] The system further includes a catheter having a distal end, a proximal end and a lumen that receives the device, the catheter being guidable into the coronary sinus adjacent to the mitral valve annulus and deploying the first and second anchors of the device within the coronary sinus adjacent to the mitral valve annulus, and a tether releasably coupled to the second anchor and extending proximally through the lumen and out of the catheter proximal end. As a result, when the first anchor is deployed by the catheter in the coronary sinus, the second anchor may be displaced proximally by proximally pulling on the tether to effect the geometry of the mitral valve annulus and thereafter released for deployment to maintain the effect on the mitral valve geometry. [20] The present invention further provides a method of effecting mitral valve annulus geometry in a heart. The method includes the steps of fixing a first anchor within the coronary sinus of the heart adjacent to the mitral valve annulus,
positioning a second anchor within the coronary sinus adjacent to the mitral valve annulus and proximal to the first anchor, fixing a fixed length connecting member between the first anchor and the second anchor, displacing the second anchor proximally to effect the geometry of the mitral valve annulus, and releasing the second anchor from further proximal displacement to maintain the effect on the mitral valve geometry. [21] The present invention further provides a device that effects mitral valve annulus geometry of a heart. The device includes a first anchor configured to be positioned within and anchored to the coronary sinus of the heart adjacent the mitral valve annulus within the heart, a second anchor configured to be positioned within the heart proximal to the first anchor and adjacent the mitral valve annulus within the heart, and a connecting member attached between the first and second anchors. At least one of the first and second anchors anchoring against movement in a first direction and being moveable in a second direction opposite the first direction. [22] The at least one anchor may be the first anchor wherein the first direction is a proximal direction and wherein the second direction is a distal direction. The at least one anchor may be the second anchor wherein the first direction is a distal direction and wherein the second direction is a proximal direction. In a preferred embodiment, the first anchor anchors against movement in a proximal direction and is moveable in a distal direction and the second anchor anchors against movement in the distal direction and is moveable in the proximal direction.
[23] The invention still further provides a device that effects mitral valve annulus geometry of a heart and which permits a cardiac lead to be implanted in the left side of the heart. The device includes a first anchor configured to be positioned within and anchored to the coronary sinus of the
heart adjacent the mitral valve annulus within the heart, a second anchor configured to be positioned within the heart proximal to the first anchor and adjacent the mitral valve annulus within the heart, and a connecting member attached between the first and second anchors . The first anchor is configured to occupy less than all of the coronary sinus to permit a cardiac lead to be passed by the first anchor. [24] The first anchor may include a loop through which the cardiac lead may be passed. The second anchor may be positionable within the coronary sinus and be configured to occupy less than all of the coronary sinus to permit the cardiac lead to be passed by the second anchor. The second anchor may also include a loop through which the cardiac lead may be passed.
BRIEF DESCRIPTION OF THE DRAWINGS [25] The features of the present invention which are believed to be novel are set forth with particularity in the appended claims. The invention, together with further aspects and advantages thereof, may best be understood by making reference to the following description taken in conjunction with the accompanying drawings, in the several figures of which like reference numerals identify identical elements, and wherein: [26] FIG. 1 is a superior view of a human heart with the atria removed;
[27] FIG. 2 is a superior view of a human heart similar to FIG. 1 illustrating a deployed mitral valve device embodying the present invention; [28] FIG. 3 is a superior view of a human heart similar to FIG. 2 illustrating a first step in the deployment of the mitral valve device of FIG. 2 embodying the present invention; [29] FIG. 4 is a view similar to FIG. 3 illustrating a further step in the deployment of the device of FIG. 2;
[30] FIG. 5 is a view similar to FIG. 3 illustrating a final step in the deployment of the device of FIG. 2 ; [31] FIG. 6 is a superior view of a human heart similar to FIG. 1 illustrating another deployed mitral valve device embodying the present invention; and
[32] FIG. 7 is a side view with a portion broken away illustrating further details of device anchors and the manner in which they permit an implantable lead to pass thereby.
DETAILED DESCRIPTION OF THE INVENTION
[33] Referring now to FIG. 1, it is a superior view of a human heart 10 with the atria removed to expose the mitral valve 12, the coronary sinus 14, the coronary artery 15, and the circumflex artery 17 of the heart 10 to lend a better understanding of the present invention.- Also generally shown in FIG. 1 are the pulmonary valve 22, the aortic valve 24, and the tricuspid valve 26 of the heart 10.
[34] The mitral valve 12 includes an anterior cusp 16, a posterior cusp 18 and an annulus 20. The annulus encircles the cusps 16 and 18 and maintains their spacing to provide a complete closure during a left ventricular contraction. As is well known, the coronary sinus 14 partially encircles the mitral valve 12 adjacent to the mitral valve annulus 20. As is also known, the coronary sinus is part of the venus system of the heart and extends along the AV groove between the left atrium and the left ventricle. This places the coronary sinus essentially within the same plane as the mitral valve annulus making the coronary sinus available for placement of the mitral valve therapy device of the present invention therein. [35] FIG. 2 shows a mitral valve therapy device 30 embodying the present invention. As may be noted in FIG. 2, the device 30 includes a first anchor 32, a connecting member 34, and a second anchor 36. The anchors 32 and 36 and the
connecting member 34 may be formed from the same material to provide an integral structure.
[36] The first anchor 32 is located at the distal end of the device 30. The anchor 32 is hook-shaped so as to be self- deployable when released in the coronary sinus 14. More specifically, the device 30 may be formed of most any biocompatible material such as stainless steel, Nitinol, a nickel/titanium alloy of the type well known in the art having shape memory or plastic. The hook-shaped configuration of the anchor 32 thus expands when released to wedge against the inner wall of the coronary sinus 14 for anchoring or fixing the anchor 32 against at least proximal movement. The anchor 32 may however allow distal movement. Preferably, the anchor 32 is positioned just proximally to the crossover point 19 of the coronary sinus 14 and a circumflex artery 17.
[37] The connecting member 34, by being formed of Nitinol, is relatively rigid and is predisposed to have an arcuate configuration to generally correspond to the shape of the mitral valve annulus 20. The connecting member 34 is of a fixed length and is permanently attached to the first and second anchors 32 and 36. Here it will be noted that the second anchor is positioned within the coronary sinus just distal to the ostium 21 of the coronary sinus 14. The second anchor 36 may have a similar hook-shaped configuration and is also preferably self- expanding to be self-deployable . The hook-shape of the anchor
36 anchors or fixes the anchor 36 against distal movement but permits the anchor to be pulled proximally. This is a particularly significant aspect of the device 30 because it permits the device to be adjusted after the anchors 32 and 36 are first deployed.
[38] When the device 30 is deployed as shown in FIG. 2, the first anchor 32 is fixed against proximal movement within the coronary sinus 14. The connecting member 34 then extends
proximally from the first anchor 32 to the second anchor 36. The second anchor 36 is then positioned in its desired location within the coronary sinus 14 proximal to the first anchor 32 and permitted to self-expand for being anchored against distal movement. Then, the second anchor 36 is pulled proximally while the first anchor 32 is held in its fixed position. This creates tension in the connecting member 34 to effect the geometry of the mitral valve annulus 20. Once a desired amount of tension is applied to the connecting member 34, the second anchor 36 is released from further movement and is redeployed against distal movement. With the connecting member 34 now under maintained tension, the advantageously effected geometry of the mitral valve annulus 20 is now preserved. The tension in the cable is preferably adjusted by the pulling on the second anchor 26 while monitoring a parameter indicative of mitral regurgitation, such as Doppler echo.
[39] The connecting member 34 may be provided with a covering (not shown) . The covering may preferably be formed of a compressible material to serve to cushion the forces of the connecting member applied against the inner wall of the coronary sinus 14.
[40] FIGS. 3 through 5 show a manner in which the device 30 may be deployed by a deployment assembly 50. As will be noted in FIG. 3, the deployment assembly 50 includes a catheter 52 and a tether 54. The catheter 52 has a lumen 56 dimensioned for slidably receiving the device 30 in its predeployed state with the tether 54 looped around the second anchor 36 and extending out the proximal end of the catheter 52. [41] As will be noted in FIG. 3, the first anchor 32 has been deployed while the second anchor remains in the catheter lumen 56. This may be accompanied by feeding the catheter 52 into the coronary sinus until the first anchor is in a desired position. Now, the catheter 52 may be moved proximally while
maintaining the first anchor 32 against movement. Proximal movement of the catheter 52 will release the anchor 32. When the anchor is released, it will self-expand to self-deploy and be fixed against proximal movement . [42] As shown in FIG. 4, the catheter 52 is further retracted to release the second anchor 36 to permit it to self- expand and to self-deploy. The second anchor 36 is now fixed against distal movement but permitted to move proximally. The tether 54 continues to extend out the proximal end of the catheter 52.
[43] As may now be further seen in FIG. 5, tension is then applied to the connecting member 34 by proximally pulling on the tether 54, and hence the second anchor 36, while the first anchor 32 resists proximal movement. When the desired tension is placed on the connecting member 34, the second anchor 36 is released for re-self-deployment . When this is completed, the first anchor 32 and the second anchor 36 are fixed in position with a tension in the connecting member 34. The catheter 52 and the tether 54 may then be removed to complete the deployment process. Although the proximal anchor 36 is shown to be finally deployed in the coronary sinus, it will be appreciated by those skilled in the art that the proximal anchor 36, after being displaced proximally, may finally be deployed within the right atrium just proximal to the ostium 21 of the coronary sinus 14. Hence, any final position of the proximal anchor 36 proximal to the distal anchor 32 and within the heart is contemplated in accordance with the present invention.
[44] In accordance with the present invention, the device 30 may be deployed in a slightly different manner as described above. Here, the first anchor 32 may be deployed as described above and the second anchor 36 left in the catheter 52 as it is moved proximally. When the second anchor 36 reaches a desired position, the catheter 52 may then be pulled back to release and
deploy the second anchor 36. As a result, in accordance with this alternative embodiment, the second anchor, when deployed, may anchor against both distal and proximal movement. [45] FIG. 6 shows another mitral valve device 70 embodying the present invention. The device 70 is similar to the device 30 previously described except that its connecting member 74 includes a spring configuration 75. The spring 75 has a maximum length and serves to more forcefully maintain the applied tension on the mitral valve annulus 20. To this end, the device 70 includes a first anchor 72, the connecting member 74, and a second anchor 76.
[46] The first and second anchors 72 and 76 are again configured so that when they are released, they self-expand, to wedge against the inner wall of the coronary sinus 14. Again, the first anchor resists proximal movement and the second anchor 76 resists distal movement. In all other respects, the device 70 may be identical to and deployed in the same manner as the device 30. [47] Implantable cardiac stimulation devices are well known in the art. Such devices may include, for example, implantable cardiac pacemakers and defibrillators . The devices are generally implanted in a pectoral region of the chest beneath the skin of a patient within what is known as a subcutaneous pocket. The implantable devices generally function in association with one or more electrode carrying leads which are implanted within the heart. The electrodes are usually positioned within the right side of the heart, either within the right ventricle or right atrium, or both, for making electrical contact with their respective heart chamber. Conductors within the leads and a proximal connector carried by the leads couple the electrodes to the device to enable the device to sense cardiac electrical activity and deliver the desired therapy.
[48] Traditionally, therapy delivery had been limited to the venous, or right side of the heart. The reason for this is that implanted electrodes can cause blood clot formation in some patients. If a blood clot were released arterially from the left heart, as for example the left ventricle, it could pass directly to the brain potentially resulting in a paralyzing or fatal stroke. However, a blood clot released from the right heart, as from the right ventricle, would pass into the lungs where the filtering action of the lungs would prevent a fatal or debilitating embolism in the brain.
[49] Recently, new lead structures and methods have been proposed and even practiced for delivering cardiac rhythm management therapy to the left heart. These lead structures and methods avoid direct electrode placement within the left atrium and left ventricle of the heart by lead implantation within the coronary sinus of the heart. As previously mentioned, the phrase "coronary sinus" refers to not only the coronary sinus itself but in addition, the venous system associated with the coronary sinus including the great cardiac vein. [50] It has been demonstrated that electrodes placed in the coronary sinus region of the heart may be used for left atrial pacing, left ventricular pacing, or cardioversion and defibrillation. These advancements enable implantable cardiac stimulation devices to address the needs of a patient population with left ventricular dysfunction and/or congestive heart failure which would benefit from left heart side pacing, either alone or in conjunction with right heart side pacing (bi-chamber pacing) , and/or defibrillation. [51] Even though the device of the present invention is implantable in the coronary sinus of the heart, it is configured in accordance with further aspects of the present invention to permit a cardiac lead to pass through the coronary sinus for functioning as described above. To that end, and as best seen
in FIG. 7, the anchors 32 and 36 of the device 30 occupy only a small portion of and hence less than all of the interior space of the coronary sinus 14. This permits a cardiac lead 80 to be advanced into the coronary sinus 14 for implant in the left side of the heart .
[52] More specifically, the anchors 32 and 36 take the form of loops 33 and 35 respectively which are then bent backwards on the device to form the previously referred to hook-shapes for self-deployment . The loops 33 and 35 thus permit the cardiac lead 80 to be passed therethrough for implant in the left heart. This is particularly desirable because many patients suffering from mitral regurgitation may also be candidates for left heart cardiac rhythm management therapy. [53] While particular embodiments of the present invention have been shown and described, modifications may be made, and it is therefore intended in the appended claims to cover all such changes and modifications which fall within the true spirit and scope of the invention as defined by the appended claims .
Claims (43)
1. A device that effects mitral valve annulus geometry of a heart, comprising: a first anchor configured to be positioned within and anchored to the coronary sinus of the heart adjacent the mitral valve annulus within the heart; a second anchor configured to be positioned within the heart proximal to the first anchor and adjacent the mitral valve annulus within the heart; and a connecting member having a fixed length permanently attached to the first and second anchors, whereby when the first and second anchors are within the heart with the first anchor anchored in the coronary sinus, the second anchor may be displaced proximally to effect the geometry of the mitral valve annulus and released to maintain the effect on the mitral valve geometry.
2. The device of claim 1 wherein the second anchor, when deployed, is configured to anchor against distal movement and moveable in a proximal direction.
3. The device of claim 2 wherein the first anchor is self- deploying upon release in the coronary sinus.
4. The device of claim 2 wherein the second anchor is self-deploying upon release in the coronary sinus .
5. The device of claim 2 wherein the connecting member is a rigid member .
6. The device of claim 2 wherein the connecting member includes a spring having a maximum length.
7. The device of claim 2 wherein the connecting member is flexible and nonstretchable.
8. A device for effecting mitral valve annulus geometry of a heart, comprising: first anchor means for anchoring in the coronary sinus of the heart adjacent the mitral valve annulus; second anchor means for being deployed within the heart proximal to the first anchor means and adjacent the mitral valve annulus; and connecting means having a fixed length and permanently connecting the first anchor means to the second anchor means , whereby when the first and second anchor means are within the heart with the first anchor means deployed, the second anchor means may be displaced proximally for cooperating with, the first anchor means and the connecting means for effecting the geometry of the mitral valve annulus and released for maintaining the effect on the mitral valve geometry.
9. The device of claim 8 wherein the second anchor means, when deployed, anchors against distal movement and is moveable in a proximal direction.
10. The device of claim 8 wherein the first anchor (means is self-deploying upon release in the coronary sinus.
11. The device of claim 8 wherein the second anchor means is self-deploying upon release in the coronary sinus.
12. The device of claim 8 wherein the connecting means is a rigid member.
13. The device of claim 8 wherein the connecting means includes a spring having a maximum length.
14. The device of claim 8 wherein the connecting means is flexible and nonstretchable.
15. The device of claim 1 wherein the first anchor occupies less than all of the coronary sinus to permit a cardiac lead to be passed by the first anchor.
16. The device of claim 15 wherein the first anchor includes a loop through which the cardiac lead may be passed.
17. The device of claim 15 wherein the second anchor also occupies less than all of the coronary sinus to permit the cardiac lead to be passed by the second anchor.
18. The device of claim 17 wherein the second anchor includes a loop through which the cardiac lead may be passed.
19. A system that effects mitral valve annulus geometry of a heart, comprising: a mitral valve device including a first anchor configured to be positioned within and anchored to the coronary sinus of the heart adjacent the mitral valve annulus within the heart, a second anchor configured to be positioned within the heart proximal to the first anchor and adjacent the mitral valve annulus within the heart, and a connecting member having a fixed length permanently attached to the first and second anchors; a catheter having a distal end, a proximal end and a lumen that receives the device, the catheter being guidable into the coronary sinus adjacent to the mitral valve annulus and deploying the first and second anchors of the device within the coronary sinus adjacent to the mitral valve annulus; and a tether releasably coupled to the second anchor and extending proximally through the lumen and out of the catheter proximal end, whereby when the first anchor is deployed by the catheter in the coronary sinus, the second anchor may be displaced proximally by proximally pulling on the tether to effect the geometry of the mitral valve annulus and thereafter released for deployment to maintain the effect on the mitral valve geometry.
20. The system of claim 19 wherein the second anchor, when deployed, is anchored against distal movement and moveable in a proximal direction.
21. The system of claim 19 wherein the first anchor is self-deploying upon release in the coronary sinus.
22. The system of claim 19 wherein the second anchor is self-deploying upon release in the coronary sinus .
23. The system of claim 19 wherein the connecting member is a rigid member.
24. The system of claim 19 wherein the connecting member includes a spring having a maximum length.
25. The system of claim 19 wherein the connecting member is flexible and nonstretchable.
26. A method of effecting mitral valve annulus geometry in a heart, the method including the steps of: fixing a first anchor within the coronary sinus of the heart adjacent to the mitral valve annulus; positioning a second anchor within the heart proximal to the first anchor; fixing a fixed length connecting member between the first anchor and the second anchor; displacing the second anchor proximally to effect the geometry of the mitral valve annulus; and releasing the second anchor from further proximal displacement to maintain the effect on the mitral valve geometry.
27. The method of claim 26 wherein the displacing step includes the steps of releasably coupling a tether to the second anchor and pulling proximally on the tether.
28. The method of claim 27 including the further step of removing the tether from the second anchor after the releasing step.
29. A method of effecting mitral valve geometry of a heart, the method including the steps of: advancing a guide catheter into the coronary sinus of the heart adjacent to the mitral valve annulus; feeding a self-deploying first anchor down and out of the guide catheter to deploy the first anchor in the coronary sinus adjacent to the mitral valve annulus; connecting a fixed length connecting member between the first anchor and a self-deploying second anchor that once deployed anchors at least against distal movement; guiding the second self-deploying anchor down the guide catheter to a position within the coronary sinus proximal to the first anchor; displacing the second anchor proximally to effect the geometry of the mitral valve annulus; withdrawing the guide catheter to release and deploy the second anchor; and releasing the second anchor to deploy the second anchor and maintain the effect on the mitral valve annulus geometry .
30. The method of claim 29 including the further step of releasably coupling a tether to the second anchor prior to the displacing step.
31. The method of claim 30 wherein the displacing step includes the step of pulling proximally on the tether.
32. The method of claim 29 wherein the feeding step includes locating the first anchor proximally to the circumflex artery within the coronary sinus.
33. A device that effects mitral valve annulus geometry of a heart, comprising: a first anchor configured to be positioned within and anchored to the coronary sinus of the heart adjacent the mitral valve annulus within the heart; a second anchor configured to be positioned within the heart proximal to the first anchor and adjacent the mitral valve annulus within the heart; and a connecting member attached between the first and second anchors, at least one of the first and second anchors anchoring against movement in a first direction and being moveable in a second direction opposite the first direction.
34. The device of claim 33 wherein the at least one anchor is the first anchor wherein the first direction is a proximal direction and wherein the second direction is a distal direction.
35. The device of claim 33 wherein the at least one anchor is the second anchor wherein the first direction is a distal direction and wherein the second direction is a proximal direction.
36. The device of claim 33 wherein the first anchor anchors against movement in a proximal direction and is moveable in a distal direction and wherein the second anchor anchors against movement in the distal direction and is moveable in the proximal direction.
37. A device that effects mitral valve annulus geometry of a heart, comprising: a first anchor configured to be positioned within and anchored to the coronary sinus of the heart adjacent the mitral valve annulus within the heart; a second anchor configured to be positioned within the heart proximal to the first anchor and adjacent the mitral valve annulus within the heart; and a connecting member attached between the first and second anchors, the first anchor being configured to occupy less than all of the coronary sinus to permit a cardiac lead to be passed by the first anchor.
38. The device of claim 37 wherein the first anchor includes a loop through which the cardiac lead may be passed.
39. The device of claim 37 wherein the second anchor is positionable within the coronary sinus and wherein the second anchor is configured to occupy less than all of the coronary sinus to permit the cardiac lead to be passed by the second anchor .
40. The device of claim 39 wherein the second anchor includes a loop through which the cardiac lead may be passed.
41. The device of claim 39 wherein each of the first and second anchors includes a loop through which the cardiac lead may be passed.
42. The device of claim 1 wherein the connecting member is flexible and nonstretchable.
43. A device for providing therapy to a mitral valve annulus of a heart, the device being elongated and dimensioned to be received within the coronary sinus of the heart adjacent to the mitral valve annulus, the device having a first radius of curvature when initially placed in the coronary sinus adjacent the mitral valve annulus and a second radius of curvature when providing therapy to the mitral valve annulus from within the coronary sinus, the second radius of curvature being greater than the first radius of curvature.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/066,426 US6976995B2 (en) | 2002-01-30 | 2002-01-30 | Fixed length anchor and pull mitral valve device and method |
| US10/066,426 | 2002-01-30 | ||
| PCT/US2003/002124 WO2003063735A2 (en) | 2002-01-30 | 2003-01-22 | Fixed length anchor and pull mitral valve device and method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2003211731A1 true AU2003211731A1 (en) | 2003-09-18 |
| AU2003211731B2 AU2003211731B2 (en) | 2009-04-02 |
Family
ID=27610485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003211731A Expired AU2003211731B2 (en) | 2002-01-30 | 2003-01-22 | Fixed length anchor and pull mitral valve device and method |
Country Status (7)
| Country | Link |
|---|---|
| US (15) | US6976995B2 (en) |
| EP (3) | EP3254644B1 (en) |
| JP (1) | JP4359660B2 (en) |
| AU (1) | AU2003211731B2 (en) |
| CA (2) | CA2469460C (en) |
| ES (3) | ES2636661T3 (en) |
| WO (1) | WO2003063735A2 (en) |
Families Citing this family (279)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7883539B2 (en) | 1997-01-02 | 2011-02-08 | Edwards Lifesciences Llc | Heart wall tension reduction apparatus and method |
| US6050936A (en) | 1997-01-02 | 2000-04-18 | Myocor, Inc. | Heart wall tension reduction apparatus |
| FR2768324B1 (en) | 1997-09-12 | 1999-12-10 | Jacques Seguin | SURGICAL INSTRUMENT FOR PERCUTANEOUSLY FIXING TWO AREAS OF SOFT TISSUE, NORMALLY MUTUALLY REMOTE, TO ONE ANOTHER |
| US6332893B1 (en) | 1997-12-17 | 2001-12-25 | Myocor, Inc. | Valve to myocardium tension members device and method |
| US6260552B1 (en) | 1998-07-29 | 2001-07-17 | Myocor, Inc. | Transventricular implant tools and devices |
| US6752813B2 (en) | 1999-04-09 | 2004-06-22 | Evalve, Inc. | Methods and devices for capturing and fixing leaflets in valve repair |
| US7666204B2 (en) | 1999-04-09 | 2010-02-23 | Evalve, Inc. | Multi-catheter steerable guiding system and methods of use |
| US8216256B2 (en) | 1999-04-09 | 2012-07-10 | Evalve, Inc. | Detachment mechanism for implantable fixation devices |
| US7811296B2 (en) | 1999-04-09 | 2010-10-12 | Evalve, Inc. | Fixation devices for variation in engagement of tissue |
| CA2369641C (en) | 1999-04-09 | 2009-02-10 | Evalve, Inc. | Methods and apparatus for cardiac valve repair |
| US20040044350A1 (en) | 1999-04-09 | 2004-03-04 | Evalve, Inc. | Steerable access sheath and methods of use |
| US6997951B2 (en) | 1999-06-30 | 2006-02-14 | Edwards Lifesciences Ag | Method and device for treatment of mitral insufficiency |
| US7507252B2 (en) * | 2000-01-31 | 2009-03-24 | Edwards Lifesciences Ag | Adjustable transluminal annuloplasty system |
| US6989028B2 (en) * | 2000-01-31 | 2006-01-24 | Edwards Lifesciences Ag | Medical system and method for remodeling an extravascular tissue structure |
| US6723038B1 (en) | 2000-10-06 | 2004-04-20 | Myocor, Inc. | Methods and devices for improving mitral valve function |
| US6602286B1 (en) | 2000-10-26 | 2003-08-05 | Ernst Peter Strecker | Implantable valve system |
| US7591826B2 (en) * | 2000-12-28 | 2009-09-22 | Cardiac Dimensions, Inc. | Device implantable in the coronary sinus to provide mitral valve therapy |
| US8038708B2 (en) | 2001-02-05 | 2011-10-18 | Cook Medical Technologies Llc | Implantable device with remodelable material and covering material |
| US7037334B1 (en) | 2001-04-24 | 2006-05-02 | Mitralign, Inc. | Method and apparatus for catheter-based annuloplasty using local plications |
| US8202315B2 (en) | 2001-04-24 | 2012-06-19 | Mitralign, Inc. | Catheter-based annuloplasty using ventricularly positioned catheter |
| US6676702B2 (en) * | 2001-05-14 | 2004-01-13 | Cardiac Dimensions, Inc. | Mitral valve therapy assembly and method |
| US6800090B2 (en) * | 2001-05-14 | 2004-10-05 | Cardiac Dimensions, Inc. | Mitral valve therapy device, system and method |
| US7311729B2 (en) * | 2002-01-30 | 2007-12-25 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
| US7635387B2 (en) | 2001-11-01 | 2009-12-22 | Cardiac Dimensions, Inc. | Adjustable height focal tissue deflector |
| US6949122B2 (en) * | 2001-11-01 | 2005-09-27 | Cardiac Dimensions, Inc. | Focused compression mitral valve device and method |
| US6824562B2 (en) * | 2002-05-08 | 2004-11-30 | Cardiac Dimensions, Inc. | Body lumen device anchor, device and assembly |
| US7179282B2 (en) | 2001-12-05 | 2007-02-20 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
| US6793673B2 (en) | 2002-12-26 | 2004-09-21 | Cardiac Dimensions, Inc. | System and method to effect mitral valve annulus of a heart |
| US6976995B2 (en) | 2002-01-30 | 2005-12-20 | Cardiac Dimensions, Inc. | Fixed length anchor and pull mitral valve device and method |
| US8075616B2 (en) * | 2001-12-28 | 2011-12-13 | Edwards Lifesciences Ag | Apparatus for applying a compressive load on body tissue |
| US6764510B2 (en) | 2002-01-09 | 2004-07-20 | Myocor, Inc. | Devices and methods for heart valve treatment |
| WO2003105670A2 (en) | 2002-01-10 | 2003-12-24 | Guided Delivery Systems, Inc. | Devices and methods for heart valve repair |
| US7351260B2 (en) | 2005-01-20 | 2008-04-01 | Cardiac Dimensions, Inc. | Tissue shaping device |
| US20050209690A1 (en) * | 2002-01-30 | 2005-09-22 | Mathis Mark L | Body lumen shaping device with cardiac leads |
| US7048754B2 (en) | 2002-03-01 | 2006-05-23 | Evalve, Inc. | Suture fasteners and methods of use |
| US7004958B2 (en) * | 2002-03-06 | 2006-02-28 | Cardiac Dimensions, Inc. | Transvenous staples, assembly and method for mitral valve repair |
| US6797001B2 (en) * | 2002-03-11 | 2004-09-28 | Cardiac Dimensions, Inc. | Device, assembly and method for mitral valve repair |
| US6752828B2 (en) | 2002-04-03 | 2004-06-22 | Scimed Life Systems, Inc. | Artificial valve |
| CA2744868C (en) | 2002-05-08 | 2015-12-29 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
| US20060122633A1 (en) | 2002-06-13 | 2006-06-08 | John To | Methods and devices for termination |
| US9949829B2 (en) | 2002-06-13 | 2018-04-24 | Ancora Heart, Inc. | Delivery devices and methods for heart valve repair |
| US7753858B2 (en) | 2002-06-13 | 2010-07-13 | Guided Delivery Systems, Inc. | Delivery devices and methods for heart valve repair |
| US9226825B2 (en) * | 2002-06-13 | 2016-01-05 | Guided Delivery Systems, Inc. | Delivery devices and methods for heart valve repair |
| US7883538B2 (en) | 2002-06-13 | 2011-02-08 | Guided Delivery Systems Inc. | Methods and devices for termination |
| US8287555B2 (en) | 2003-02-06 | 2012-10-16 | Guided Delivery Systems, Inc. | Devices and methods for heart valve repair |
| US7753922B2 (en) | 2003-09-04 | 2010-07-13 | Guided Delivery Systems, Inc. | Devices and methods for cardiac annulus stabilization and treatment |
| US7666193B2 (en) | 2002-06-13 | 2010-02-23 | Guided Delivery Sytems, Inc. | Delivery devices and methods for heart valve repair |
| US7758637B2 (en) * | 2003-02-06 | 2010-07-20 | Guided Delivery Systems, Inc. | Delivery devices and methods for heart valve repair |
| US8641727B2 (en) | 2002-06-13 | 2014-02-04 | Guided Delivery Systems, Inc. | Devices and methods for heart valve repair |
| US20050216078A1 (en) * | 2002-06-13 | 2005-09-29 | Guided Delivery Systems, Inc. | Delivery devices and methods for heart valve repair |
| US7087064B1 (en) | 2002-10-15 | 2006-08-08 | Advanced Cardiovascular Systems, Inc. | Apparatuses and methods for heart valve repair |
| WO2004037317A2 (en) | 2002-10-21 | 2004-05-06 | Mitralign Incorporated | Method and apparatus for performing catheter-based annuloplasty using local plications |
| US8979923B2 (en) * | 2002-10-21 | 2015-03-17 | Mitralign, Inc. | Tissue fastening systems and methods utilizing magnetic guidance |
| US7112219B2 (en) | 2002-11-12 | 2006-09-26 | Myocor, Inc. | Devices and methods for heart valve treatment |
| US7485143B2 (en) | 2002-11-15 | 2009-02-03 | Abbott Cardiovascular Systems Inc. | Apparatuses and methods for heart valve repair |
| US9149602B2 (en) | 2005-04-22 | 2015-10-06 | Advanced Cardiovascular Systems, Inc. | Dual needle delivery system |
| US7404824B1 (en) | 2002-11-15 | 2008-07-29 | Advanced Cardiovascular Systems, Inc. | Valve aptation assist device |
| US7335213B1 (en) | 2002-11-15 | 2008-02-26 | Abbott Cardiovascular Systems Inc. | Apparatus and methods for heart valve repair |
| US8187324B2 (en) * | 2002-11-15 | 2012-05-29 | Advanced Cardiovascular Systems, Inc. | Telescoping apparatus for delivering and adjusting a medical device in a vessel |
| US7981152B1 (en) | 2004-12-10 | 2011-07-19 | Advanced Cardiovascular Systems, Inc. | Vascular delivery system for accessing and delivering devices into coronary sinus and other vascular sites |
| US7316708B2 (en) * | 2002-12-05 | 2008-01-08 | Cardiac Dimensions, Inc. | Medical device delivery system |
| US7837729B2 (en) * | 2002-12-05 | 2010-11-23 | Cardiac Dimensions, Inc. | Percutaneous mitral valve annuloplasty delivery system |
| US6945957B2 (en) | 2002-12-30 | 2005-09-20 | Scimed Life Systems, Inc. | Valve treatment catheter and methods |
| US20040133240A1 (en) * | 2003-01-07 | 2004-07-08 | Cardiac Dimensions, Inc. | Electrotherapy system, device, and method for treatment of cardiac valve dysfunction |
| US7314485B2 (en) | 2003-02-03 | 2008-01-01 | Cardiac Dimensions, Inc. | Mitral valve device using conditioned shape memory alloy |
| US20040158321A1 (en) * | 2003-02-12 | 2004-08-12 | Cardiac Dimensions, Inc. | Method of implanting a mitral valve therapy device |
| US20040254600A1 (en) * | 2003-02-26 | 2004-12-16 | David Zarbatany | Methods and devices for endovascular mitral valve correction from the left coronary sinus |
| JP4691017B2 (en) * | 2003-03-18 | 2011-06-01 | セント ジュード メディカル インコーポレイテッド | Body tissue remodeling method and apparatus |
| US7625399B2 (en) * | 2003-04-24 | 2009-12-01 | Cook Incorporated | Intralumenally-implantable frames |
| US7717952B2 (en) | 2003-04-24 | 2010-05-18 | Cook Incorporated | Artificial prostheses with preferred geometries |
| US7658759B2 (en) | 2003-04-24 | 2010-02-09 | Cook Incorporated | Intralumenally implantable frames |
| DE602004023708D1 (en) | 2003-04-24 | 2009-12-03 | Cook Inc | ARTIFICIAL FLAP FLAP WITH IMPROVED FLOW BEHAVIOR |
| US20040220657A1 (en) * | 2003-05-02 | 2004-11-04 | Cardiac Dimensions, Inc., A Washington Corporation | Tissue shaping device with conformable anchors |
| US20040220654A1 (en) | 2003-05-02 | 2004-11-04 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
| US10667823B2 (en) | 2003-05-19 | 2020-06-02 | Evalve, Inc. | Fixation devices, systems and methods for engaging tissue |
| US7887582B2 (en) | 2003-06-05 | 2011-02-15 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
| US7351259B2 (en) | 2003-06-05 | 2008-04-01 | Cardiac Dimensions, Inc. | Device, system and method to affect the mitral valve annulus of a heart |
| US8052751B2 (en) * | 2003-07-02 | 2011-11-08 | Flexcor, Inc. | Annuloplasty rings for repairing cardiac valves |
| EP1646332B1 (en) | 2003-07-18 | 2015-06-17 | Edwards Lifesciences AG | Remotely activated mitral annuloplasty system |
| US7998112B2 (en) | 2003-09-30 | 2011-08-16 | Abbott Cardiovascular Systems Inc. | Deflectable catheter assembly and method of making same |
| US7004176B2 (en) * | 2003-10-17 | 2006-02-28 | Edwards Lifesciences Ag | Heart valve leaflet locator |
| US8128681B2 (en) | 2003-12-19 | 2012-03-06 | Boston Scientific Scimed, Inc. | Venous valve apparatus, system, and method |
| US7854761B2 (en) | 2003-12-19 | 2010-12-21 | Boston Scientific Scimed, Inc. | Methods for venous valve replacement with a catheter |
| US7837728B2 (en) * | 2003-12-19 | 2010-11-23 | Cardiac Dimensions, Inc. | Reduced length tissue shaping device |
| US9526616B2 (en) | 2003-12-19 | 2016-12-27 | Cardiac Dimensions Pty. Ltd. | Mitral valve annuloplasty device with twisted anchor |
| US20050137449A1 (en) * | 2003-12-19 | 2005-06-23 | Cardiac Dimensions, Inc. | Tissue shaping device with self-expanding anchors |
| US7794496B2 (en) | 2003-12-19 | 2010-09-14 | Cardiac Dimensions, Inc. | Tissue shaping device with integral connector and crimp |
| US8864822B2 (en) * | 2003-12-23 | 2014-10-21 | Mitralign, Inc. | Devices and methods for introducing elements into tissue |
| US7166127B2 (en) * | 2003-12-23 | 2007-01-23 | Mitralign, Inc. | Tissue fastening systems and methods utilizing magnetic guidance |
| WO2005087139A1 (en) * | 2004-03-15 | 2005-09-22 | Baker Medical Research Institute | Treating valve failure |
| US7993397B2 (en) * | 2004-04-05 | 2011-08-09 | Edwards Lifesciences Ag | Remotely adjustable coronary sinus implant |
| EP3628239B1 (en) | 2004-05-14 | 2022-04-27 | Evalve, Inc. | Locking mechanisms for fixation devices for engaging tissue |
| US7566343B2 (en) | 2004-09-02 | 2009-07-28 | Boston Scientific Scimed, Inc. | Cardiac valve, system, and method |
| CA2581852C (en) | 2004-09-27 | 2012-11-13 | Evalve, Inc. | Methods and devices for tissue grasping and assessment |
| US8052592B2 (en) | 2005-09-27 | 2011-11-08 | Evalve, Inc. | Methods and devices for tissue grasping and assessment |
| US7211110B2 (en) * | 2004-12-09 | 2007-05-01 | Edwards Lifesciences Corporation | Diagnostic kit to assist with heart valve annulus adjustment |
| US7854755B2 (en) | 2005-02-01 | 2010-12-21 | Boston Scientific Scimed, Inc. | Vascular catheter, system, and method |
| US20060173490A1 (en) | 2005-02-01 | 2006-08-03 | Boston Scientific Scimed, Inc. | Filter system and method |
| US7878966B2 (en) | 2005-02-04 | 2011-02-01 | Boston Scientific Scimed, Inc. | Ventricular assist and support device |
| US7780722B2 (en) | 2005-02-07 | 2010-08-24 | Boston Scientific Scimed, Inc. | Venous valve apparatus, system, and method |
| US7670368B2 (en) | 2005-02-07 | 2010-03-02 | Boston Scientific Scimed, Inc. | Venous valve apparatus, system, and method |
| US7867274B2 (en) | 2005-02-23 | 2011-01-11 | Boston Scientific Scimed, Inc. | Valve apparatus, system and method |
| WO2006097931A2 (en) | 2005-03-17 | 2006-09-21 | Valtech Cardio, Ltd. | Mitral valve treatment techniques |
| US7722666B2 (en) | 2005-04-15 | 2010-05-25 | Boston Scientific Scimed, Inc. | Valve apparatus, system and method |
| US7357815B2 (en) * | 2005-04-21 | 2008-04-15 | Micardia Corporation | Dynamically adjustable implants and methods for reshaping tissue |
| US8333777B2 (en) | 2005-04-22 | 2012-12-18 | Benvenue Medical, Inc. | Catheter-based tissue remodeling devices and methods |
| US8012198B2 (en) | 2005-06-10 | 2011-09-06 | Boston Scientific Scimed, Inc. | Venous valve, system, and method |
| US8951285B2 (en) | 2005-07-05 | 2015-02-10 | Mitralign, Inc. | Tissue anchor, anchoring system and methods of using the same |
| US9492277B2 (en) | 2005-08-30 | 2016-11-15 | Mayo Foundation For Medical Education And Research | Soft body tissue remodeling methods and apparatus |
| US7569071B2 (en) | 2005-09-21 | 2009-08-04 | Boston Scientific Scimed, Inc. | Venous valve, system, and method with sinus pocket |
| US7799038B2 (en) | 2006-01-20 | 2010-09-21 | Boston Scientific Scimed, Inc. | Translumenal apparatus, system, and method |
| WO2007136532A2 (en) * | 2006-05-03 | 2007-11-29 | St. Jude Medical, Inc. | Soft body tissue remodeling methods and apparatus |
| US11285005B2 (en) | 2006-07-17 | 2022-03-29 | Cardiac Dimensions Pty. Ltd. | Mitral valve annuloplasty device with twisted anchor |
| US8388680B2 (en) | 2006-10-18 | 2013-03-05 | Guided Delivery Systems, Inc. | Methods and devices for catheter advancement and delivery of substances therethrough |
| WO2010004546A1 (en) | 2008-06-16 | 2010-01-14 | Valtech Cardio, Ltd. | Annuloplasty devices and methods of delivery therefor |
| US9883943B2 (en) | 2006-12-05 | 2018-02-06 | Valtech Cardio, Ltd. | Implantation of repair devices in the heart |
| WO2008068756A2 (en) | 2006-12-05 | 2008-06-12 | Valtech Cardio, Ltd. | Segmented ring placement |
| US11259924B2 (en) | 2006-12-05 | 2022-03-01 | Valtech Cardio Ltd. | Implantation of repair devices in the heart |
| WO2008091493A1 (en) | 2007-01-08 | 2008-07-31 | California Institute Of Technology | In-situ formation of a valve |
| WO2008097589A1 (en) | 2007-02-05 | 2008-08-14 | Boston Scientific Limited | Percutaneous valve, system, and method |
| US8911461B2 (en) | 2007-03-13 | 2014-12-16 | Mitralign, Inc. | Suture cutter and method of cutting suture |
| US20080228266A1 (en) * | 2007-03-13 | 2008-09-18 | Mitralign, Inc. | Plication assistance devices and methods |
| US11660190B2 (en) | 2007-03-13 | 2023-05-30 | Edwards Lifesciences Corporation | Tissue anchors, systems and methods, and devices |
| US8828079B2 (en) | 2007-07-26 | 2014-09-09 | Boston Scientific Scimed, Inc. | Circulatory valve, system and method |
| US7892276B2 (en) | 2007-12-21 | 2011-02-22 | Boston Scientific Scimed, Inc. | Valve with delayed leaflet deployment |
| US8790367B2 (en) | 2008-02-06 | 2014-07-29 | Guided Delivery Systems Inc. | Multi-window guide tunnel |
| US8382829B1 (en) | 2008-03-10 | 2013-02-26 | Mitralign, Inc. | Method to reduce mitral regurgitation by cinching the commissure of the mitral valve |
| WO2009137712A1 (en) | 2008-05-07 | 2009-11-12 | Guided Delivery Systems Inc. | Deflectable guide |
| US8006594B2 (en) | 2008-08-11 | 2011-08-30 | Cardiac Dimensions, Inc. | Catheter cutting tool |
| US8945211B2 (en) | 2008-09-12 | 2015-02-03 | Mitralign, Inc. | Tissue plication device and method for its use |
| KR20110084911A (en) | 2008-10-10 | 2011-07-26 | 가이디드 딜리버리 시스템즈 인코퍼레이티드 | Termination devices and related methods |
| WO2010042857A1 (en) | 2008-10-10 | 2010-04-15 | Guided Delivery Systems Inc. | Tether tensioning devices and related methods |
| US9011530B2 (en) | 2008-12-22 | 2015-04-21 | Valtech Cardio, Ltd. | Partially-adjustable annuloplasty structure |
| US8241351B2 (en) | 2008-12-22 | 2012-08-14 | Valtech Cardio, Ltd. | Adjustable partial annuloplasty ring and mechanism therefor |
| US8911494B2 (en) | 2009-05-04 | 2014-12-16 | Valtech Cardio, Ltd. | Deployment techniques for annuloplasty ring |
| EP2379008B1 (en) | 2008-12-22 | 2021-02-17 | Valtech Cardio, Ltd. | Adjustable annuloplasty devices |
| US10517719B2 (en) | 2008-12-22 | 2019-12-31 | Valtech Cardio, Ltd. | Implantation of repair devices in the heart |
| US8715342B2 (en) | 2009-05-07 | 2014-05-06 | Valtech Cardio, Ltd. | Annuloplasty ring with intra-ring anchoring |
| US20100198192A1 (en) | 2009-01-20 | 2010-08-05 | Eugene Serina | Anchor deployment devices and related methods |
| US8353956B2 (en) | 2009-02-17 | 2013-01-15 | Valtech Cardio, Ltd. | Actively-engageable movement-restriction mechanism for use with an annuloplasty structure |
| US9968452B2 (en) | 2009-05-04 | 2018-05-15 | Valtech Cardio, Ltd. | Annuloplasty ring delivery cathethers |
| US9180007B2 (en) | 2009-10-29 | 2015-11-10 | Valtech Cardio, Ltd. | Apparatus and method for guide-wire based advancement of an adjustable implant |
| US10098737B2 (en) | 2009-10-29 | 2018-10-16 | Valtech Cardio, Ltd. | Tissue anchor for annuloplasty device |
| US9011520B2 (en) | 2009-10-29 | 2015-04-21 | Valtech Cardio, Ltd. | Tissue anchor for annuloplasty device |
| US8734467B2 (en) | 2009-12-02 | 2014-05-27 | Valtech Cardio, Ltd. | Delivery tool for implantation of spool assembly coupled to a helical anchor |
| US8870950B2 (en) | 2009-12-08 | 2014-10-28 | Mitral Tech Ltd. | Rotation-based anchoring of an implant |
| US8475525B2 (en) | 2010-01-22 | 2013-07-02 | 4Tech Inc. | Tricuspid valve repair using tension |
| US9307980B2 (en) * | 2010-01-22 | 2016-04-12 | 4Tech Inc. | Tricuspid valve repair using tension |
| US10058323B2 (en) | 2010-01-22 | 2018-08-28 | 4 Tech Inc. | Tricuspid valve repair using tension |
| US8961596B2 (en) | 2010-01-22 | 2015-02-24 | 4Tech Inc. | Method and apparatus for tricuspid valve repair using tension |
| US9107749B2 (en) | 2010-02-03 | 2015-08-18 | Edwards Lifesciences Corporation | Methods for treating a heart |
| US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
| US11653910B2 (en) | 2010-07-21 | 2023-05-23 | Cardiovalve Ltd. | Helical anchor implantation |
| US9861350B2 (en) | 2010-09-03 | 2018-01-09 | Ancora Heart, Inc. | Devices and methods for anchoring tissue |
| WO2012068541A2 (en) | 2010-11-18 | 2012-05-24 | Pavilion Medical Innovations | Tissue restraining devices and methods of use |
| US9198756B2 (en) | 2010-11-18 | 2015-12-01 | Pavilion Medical Innovations, Llc | Tissue restraining devices and methods of use |
| GB201100137D0 (en) | 2011-01-06 | 2011-02-23 | Davies Helen C S | Apparatus and method of assessing a narrowing in a fluid tube |
| WO2012127309A1 (en) | 2011-03-21 | 2012-09-27 | Ontorfano Matteo | Disk-based valve apparatus and method for the treatment of valve dysfunction |
| US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
| US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
| US10792152B2 (en) | 2011-06-23 | 2020-10-06 | Valtech Cardio, Ltd. | Closed band for percutaneous annuloplasty |
| WO2013003228A1 (en) | 2011-06-27 | 2013-01-03 | University Of Maryland, Baltimore | Transapical mitral valve repair device |
| CA2842288A1 (en) | 2011-07-21 | 2013-01-24 | 4Tech Inc. | Method and apparatus for tricuspid valve repair using tension |
| US9668859B2 (en) | 2011-08-05 | 2017-06-06 | California Institute Of Technology | Percutaneous heart valve delivery systems |
| CA2846058A1 (en) | 2011-08-20 | 2013-02-28 | Volcano Corporation | Devices, systems, and methods for visually depicting a vessel and evaluating treatment options |
| US9339348B2 (en) | 2011-08-20 | 2016-05-17 | Imperial Colege of Science, Technology and Medicine | Devices, systems, and methods for assessing a vessel |
| US8945177B2 (en) | 2011-09-13 | 2015-02-03 | Abbott Cardiovascular Systems Inc. | Gripper pusher mechanism for tissue apposition systems |
| US8858623B2 (en) | 2011-11-04 | 2014-10-14 | Valtech Cardio, Ltd. | Implant having multiple rotational assemblies |
| EP2775896B1 (en) | 2011-11-08 | 2020-01-01 | Valtech Cardio, Ltd. | Controlled steering functionality for implant-delivery tool |
| EP2790609B1 (en) | 2011-12-12 | 2015-09-09 | David Alon | Heart valve repair device |
| WO2013120082A1 (en) | 2012-02-10 | 2013-08-15 | Kassab Ghassan S | Methods and uses of biological tissues for various stent and other medical applications |
| US10076414B2 (en) | 2012-02-13 | 2018-09-18 | Mitraspan, Inc. | Method and apparatus for repairing a mitral valve |
| EP2814428A4 (en) | 2012-02-13 | 2016-05-25 | Mitraspan Inc | Method and apparatus for repairing a mitral valve |
| US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
| US8961594B2 (en) | 2012-05-31 | 2015-02-24 | 4Tech Inc. | Heart valve repair system |
| EP2900150B1 (en) | 2012-09-29 | 2018-04-18 | Mitralign, Inc. | Plication lock delivery system |
| WO2014064695A2 (en) | 2012-10-23 | 2014-05-01 | Valtech Cardio, Ltd. | Percutaneous tissue anchor techniques |
| US9949828B2 (en) | 2012-10-23 | 2018-04-24 | Valtech Cardio, Ltd. | Controlled steering functionality for implant-delivery tool |
| US9730793B2 (en) | 2012-12-06 | 2017-08-15 | Valtech Cardio, Ltd. | Techniques for guide-wire based advancement of a tool |
| US9788948B2 (en) | 2013-01-09 | 2017-10-17 | 4 Tech Inc. | Soft tissue anchors and implantation techniques |
| US9681952B2 (en) | 2013-01-24 | 2017-06-20 | Mitraltech Ltd. | Anchoring of prosthetic valve supports |
| EP4215163A1 (en) | 2013-02-11 | 2023-07-26 | Cook Medical Technologies LLC | Expandable support frame and medical device |
| EP2961351B1 (en) | 2013-02-26 | 2018-11-28 | Mitralign, Inc. | Devices for percutaneous tricuspid valve repair |
| US10449333B2 (en) | 2013-03-14 | 2019-10-22 | Valtech Cardio, Ltd. | Guidewire feeder |
| US9907681B2 (en) | 2013-03-14 | 2018-03-06 | 4Tech Inc. | Stent with tether interface |
| WO2014152503A1 (en) | 2013-03-15 | 2014-09-25 | Mitralign, Inc. | Translation catheters, systems, and methods of use thereof |
| US9744037B2 (en) | 2013-03-15 | 2017-08-29 | California Institute Of Technology | Handle mechanism and functionality for repositioning and retrieval of transcatheter heart valves |
| US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
| US9607612B2 (en) | 2013-05-20 | 2017-03-28 | Intel Corporation | Natural human-computer interaction for virtual personal assistant systems |
| US9801710B2 (en) * | 2013-07-09 | 2017-10-31 | Edwards Lifesciences Corporation | Collapsible cardiac implant and deployment system and methods |
| US8870948B1 (en) | 2013-07-17 | 2014-10-28 | Cephea Valve Technologies, Inc. | System and method for cardiac valve repair and replacement |
| US10070857B2 (en) | 2013-08-31 | 2018-09-11 | Mitralign, Inc. | Devices and methods for locating and implanting tissue anchors at mitral valve commissure |
| WO2015059699A2 (en) | 2013-10-23 | 2015-04-30 | Valtech Cardio, Ltd. | Anchor magazine |
| US10052095B2 (en) | 2013-10-30 | 2018-08-21 | 4Tech Inc. | Multiple anchoring-point tension system |
| US10022114B2 (en) | 2013-10-30 | 2018-07-17 | 4Tech Inc. | Percutaneous tether locking |
| EP3062709A2 (en) | 2013-10-30 | 2016-09-07 | 4Tech Inc. | Multiple anchoring-point tension system |
| US9610162B2 (en) | 2013-12-26 | 2017-04-04 | Valtech Cardio, Ltd. | Implantation of flexible implant |
| US9681864B1 (en) | 2014-01-03 | 2017-06-20 | Harpoon Medical, Inc. | Method and apparatus for transapical procedures on a mitral valve |
| US10390943B2 (en) | 2014-03-17 | 2019-08-27 | Evalve, Inc. | Double orifice device for transcatheter mitral valve replacement |
| US9572666B2 (en) | 2014-03-17 | 2017-02-21 | Evalve, Inc. | Mitral valve fixation device removal devices and methods |
| US9801720B2 (en) | 2014-06-19 | 2017-10-31 | 4Tech Inc. | Cardiac tissue cinching |
| US10524910B2 (en) | 2014-07-30 | 2020-01-07 | Mitraltech Ltd. 3 Ariel Sharon Avenue | Articulatable prosthetic valve |
| US10195030B2 (en) | 2014-10-14 | 2019-02-05 | Valtech Cardio, Ltd. | Leaflet-restraining techniques |
| CN106999178B (en) | 2014-12-02 | 2019-12-24 | 4科技有限公司 | Eccentric tissue anchor |
| EP4306080A3 (en) | 2014-12-09 | 2024-04-10 | Cephea Valve Technologies, Inc. | Replacement cardiac valves and method of manufacture |
| US10188392B2 (en) | 2014-12-19 | 2019-01-29 | Abbott Cardiovascular Systems, Inc. | Grasping for tissue repair |
| CN110141399B (en) | 2015-02-05 | 2021-07-27 | 卡迪尔维尔福股份有限公司 | Prosthetic valve with axially sliding frame |
| US20160256269A1 (en) | 2015-03-05 | 2016-09-08 | Mitralign, Inc. | Devices for treating paravalvular leakage and methods use thereof |
| WO2016141358A1 (en) | 2015-03-05 | 2016-09-09 | Guided Delivery Systems Inc. | Devices and methods of visualizing and determining depth of penetration in cardiac tissue |
| US10524912B2 (en) | 2015-04-02 | 2020-01-07 | Abbott Cardiovascular Systems, Inc. | Tissue fixation devices and methods |
| WO2016174669A1 (en) | 2015-04-30 | 2016-11-03 | Valtech Cardio Ltd. | Annuloplasty technologies |
| CA2985659A1 (en) | 2015-05-12 | 2016-11-17 | Ancora Heart, Inc. | Device and method for releasing catheters from cardiac structures |
| EP3294221B1 (en) | 2015-05-14 | 2024-03-06 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
| US10849746B2 (en) | 2015-05-14 | 2020-12-01 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices and systems |
| US10376673B2 (en) | 2015-06-19 | 2019-08-13 | Evalve, Inc. | Catheter guiding system and methods |
| US10238494B2 (en) | 2015-06-29 | 2019-03-26 | Evalve, Inc. | Self-aligning radiopaque ring |
| US10667815B2 (en) | 2015-07-21 | 2020-06-02 | Evalve, Inc. | Tissue grasping devices and related methods |
| US10413408B2 (en) | 2015-08-06 | 2019-09-17 | Evalve, Inc. | Delivery catheter systems, methods, and devices |
| EP3355804B1 (en) | 2015-10-02 | 2020-07-15 | Harpoon Medical, Inc. | Distal anchor apparatus for mitral valve repair |
| US10238495B2 (en) | 2015-10-09 | 2019-03-26 | Evalve, Inc. | Delivery catheter handle and methods of use |
| AU2016366840B2 (en) * | 2015-12-10 | 2021-09-23 | Mvrx, Inc. | Devices, systems, and methods for reshaping a heart valve annulus |
| DK3389557T3 (en) | 2015-12-15 | 2022-08-01 | Neovasc Tiara Inc | Transseptalt leveringssystem |
| US10828160B2 (en) | 2015-12-30 | 2020-11-10 | Edwards Lifesciences Corporation | System and method for reducing tricuspid regurgitation |
| US10751182B2 (en) | 2015-12-30 | 2020-08-25 | Edwards Lifesciences Corporation | System and method for reshaping right heart |
| EP3407835A4 (en) | 2016-01-29 | 2019-06-26 | Neovasc Tiara Inc. | Prosthetic valve for avoiding obstruction of outflow |
| US10531866B2 (en) | 2016-02-16 | 2020-01-14 | Cardiovalve Ltd. | Techniques for providing a replacement valve and transseptal communication |
| US10624743B2 (en) | 2016-04-22 | 2020-04-21 | Edwards Lifesciences Corporation | Beating-heart mitral valve chordae replacement |
| US10702274B2 (en) | 2016-05-26 | 2020-07-07 | Edwards Lifesciences Corporation | Method and system for closing left atrial appendage |
| EP3471665B1 (en) | 2016-06-17 | 2023-10-11 | Cephea Valve Technologies, Inc. | Cardiac valve delivery devices |
| US10736632B2 (en) | 2016-07-06 | 2020-08-11 | Evalve, Inc. | Methods and devices for valve clip excision |
| GB201611910D0 (en) | 2016-07-08 | 2016-08-24 | Valtech Cardio Ltd | Adjustable annuloplasty device with alternating peaks and troughs |
| GB201613219D0 (en) | 2016-08-01 | 2016-09-14 | Mitraltech Ltd | Minimally-invasive delivery systems |
| CN109789018B (en) | 2016-08-10 | 2022-04-26 | 卡迪尔维尔福股份有限公司 | Prosthetic valve with coaxial frame |
| US11071564B2 (en) | 2016-10-05 | 2021-07-27 | Evalve, Inc. | Cardiac valve cutting device |
| US10363138B2 (en) | 2016-11-09 | 2019-07-30 | Evalve, Inc. | Devices for adjusting the curvature of cardiac valve structures |
| US10398553B2 (en) | 2016-11-11 | 2019-09-03 | Evalve, Inc. | Opposing disk device for grasping cardiac valve tissue |
| US10426616B2 (en) | 2016-11-17 | 2019-10-01 | Evalve, Inc. | Cardiac implant delivery system |
| WO2018094258A1 (en) | 2016-11-18 | 2018-05-24 | Ancora Heart, Inc. | Myocardial implant load sharing device and methods to promote lv function |
| JP2019535415A (en) | 2016-11-21 | 2019-12-12 | ニオバスク ティアラ インコーポレイテッド | Method and system for rapid retraction of a transcatheter heart valve delivery system |
| US10779837B2 (en) | 2016-12-08 | 2020-09-22 | Evalve, Inc. | Adjustable arm device for grasping tissues |
| US10314586B2 (en) | 2016-12-13 | 2019-06-11 | Evalve, Inc. | Rotatable device and method for fixing tricuspid valve tissue |
| CN115137529A (en) | 2016-12-21 | 2022-10-04 | 特里弗洛心血管公司 | Heart valve support devices and methods for making and using the same |
| AU2018203053B2 (en) | 2017-01-23 | 2020-03-05 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
| CR20190381A (en) | 2017-01-23 | 2019-09-27 | Cephea Valve Tech Inc | Replacement mitral valves |
| US10390953B2 (en) | 2017-03-08 | 2019-08-27 | Cardiac Dimensions Pty. Ltd. | Methods and devices for reducing paravalvular leakage |
| US10765515B2 (en) | 2017-04-06 | 2020-09-08 | University Of Maryland, Baltimore | Distal anchor apparatus and methods for mitral valve repair |
| US11045627B2 (en) | 2017-04-18 | 2021-06-29 | Edwards Lifesciences Corporation | Catheter system with linear actuation control mechanism |
| US11065119B2 (en) | 2017-05-12 | 2021-07-20 | Evalve, Inc. | Long arm valve repair clip |
| CA3065223C (en) | 2017-06-19 | 2024-05-07 | Harpoon Medical, Inc. | Method and apparatus for cardiac procedures |
| US12064347B2 (en) | 2017-08-03 | 2024-08-20 | Cardiovalve Ltd. | Prosthetic heart valve |
| US11793633B2 (en) | 2017-08-03 | 2023-10-24 | Cardiovalve Ltd. | Prosthetic heart valve |
| US10856984B2 (en) | 2017-08-25 | 2020-12-08 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
| WO2019051587A1 (en) | 2017-09-12 | 2019-03-21 | Cheema Asim | Apparatus and system for changing mitral valve annulus geometry |
| WO2019079788A1 (en) | 2017-10-20 | 2019-04-25 | Boston Scientific Scimed, Inc. | Heart valve repair implant for treating tricuspid regurgitation |
| US11065120B2 (en) | 2017-10-24 | 2021-07-20 | University Of Maryland, Baltimore | Method and apparatus for cardiac procedures |
| US10835221B2 (en) | 2017-11-02 | 2020-11-17 | Valtech Cardio, Ltd. | Implant-cinching devices and systems |
| US11135062B2 (en) | 2017-11-20 | 2021-10-05 | Valtech Cardio Ltd. | Cinching of dilated heart muscle |
| CA3086884A1 (en) | 2018-01-24 | 2019-08-01 | Valtech Cardio, Ltd. | Contraction of an annuloplasty structure |
| EP4248904A3 (en) | 2018-01-26 | 2023-11-29 | Edwards Lifesciences Innovation (Israel) Ltd. | Techniques for facilitating heart valve tethering and chord replacement |
| US11285003B2 (en) | 2018-03-20 | 2022-03-29 | Medtronic Vascular, Inc. | Prolapse prevention device and methods of use thereof |
| US11026791B2 (en) | 2018-03-20 | 2021-06-08 | Medtronic Vascular, Inc. | Flexible canopy valve repair systems and methods of use |
| US11517435B2 (en) | 2018-05-04 | 2022-12-06 | Edwards Lifesciences Corporation | Ring-based prosthetic cardiac valve |
| JP7387731B2 (en) | 2018-07-12 | 2023-11-28 | エドワーズ ライフサイエンシーズ イノベーション （イスラエル） リミテッド | Annuloplasty system and its locking tools |
| US12102531B2 (en) | 2018-10-22 | 2024-10-01 | Evalve, Inc. | Tissue cutting systems, devices and methods |
| CN113271890B (en) | 2018-11-08 | 2024-08-30 | 内奥瓦斯克迪亚拉公司 | Ventricular deployment of transcatheter mitral valve prosthesis |
| AU2020233892A1 (en) | 2019-03-08 | 2021-11-04 | Neovasc Tiara Inc. | Retrievable prosthesis delivery system |
| WO2020206012A1 (en) | 2019-04-01 | 2020-10-08 | Neovasc Tiara Inc. | Controllably deployable prosthetic valve |
| CA3136334A1 (en) | 2019-04-10 | 2020-10-15 | Neovasc Tiara Inc. | Prosthetic valve with natural blood flow |
| CN109925096A (en) * | 2019-04-29 | 2019-06-25 | 上海方维医疗科技有限公司 | For reducing the device of annulus of mitral valve opening area |
| CA3140925A1 (en) | 2019-05-20 | 2020-11-26 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
| CN113873971A (en) | 2019-05-22 | 2021-12-31 | 特里弗洛心血管公司 | Heart valve support device |
| AU2020295566B2 (en) | 2019-06-20 | 2023-07-20 | Neovasc Tiara Inc. | Low profile prosthetic mitral valve |
| US12048624B2 (en) | 2019-07-15 | 2024-07-30 | Evalve, Inc. | Independent proximal element actuation methods |
| CN114727830A (en) | 2019-07-15 | 2022-07-08 | 复心公司 | Tether cutting device and method |
| MX2021015000A (en) | 2019-10-29 | 2022-01-24 | Valtech Cardio Ltd | Annuloplasty and tissue anchor technologies. |
| US12048448B2 (en) | 2020-05-06 | 2024-07-30 | Evalve, Inc. | Leaflet grasping and cutting device |
| JP2023527304A (en) | 2020-05-20 | 2023-06-28 | カーディアック・インプランツ・エルエルシー | Heart valve annulus diameter reduction by independently controlling each anchor driven into the heart valve annulus |
| US11857417B2 (en) | 2020-08-16 | 2024-01-02 | Trilio Medical Ltd. | Leaflet support |
| AU2021400419A1 (en) | 2020-12-14 | 2023-06-29 | Cardiac Dimensions Pty. Ltd. | Modular pre-loaded medical implants and delivery systems |
Family Cites Families (252)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB741604A (en) | 1952-10-16 | 1955-12-07 | S & R J Everett & Co Ltd | Improvements relating to hypodermic syringes |
| US3620212A (en) | 1970-06-15 | 1971-11-16 | Robert D Fannon Jr | Intrauterine contraceptive device |
| US3786806A (en) * | 1972-11-22 | 1974-01-22 | A Johnson | Thermoconstrictive surgical appliance |
| US3974526A (en) | 1973-07-06 | 1976-08-17 | Dardik Irving I | Vascular prostheses and process for producing the same |
| US3890977A (en) * | 1974-03-01 | 1975-06-24 | Bruce C Wilson | Kinetic memory electrodes, catheters and cannulae |
| US3995623A (en) | 1974-12-23 | 1976-12-07 | American Hospital Supply Corporation | Multipurpose flow-directed catheter |
| FR2306671A1 (en) | 1975-04-11 | 1976-11-05 | Rhone Poulenc Ind | VALVULAR IMPLANT |
| US4164046A (en) | 1977-05-16 | 1979-08-14 | Cooley Denton | Valve prosthesis |
| US4588395A (en) | 1978-03-10 | 1986-05-13 | Lemelson Jerome H | Catheter and method |
| US4485816A (en) | 1981-06-25 | 1984-12-04 | Alchemia | Shape-memory surgical staple apparatus and method for use in surgical suturing |
| US4550870A (en) | 1983-10-13 | 1985-11-05 | Alchemia Ltd. Partnership | Stapling device |
| US5190546A (en) | 1983-10-14 | 1993-03-02 | Raychem Corporation | Medical devices incorporating SIM alloy elements |
| CA1303298C (en) | 1986-08-06 | 1992-06-16 | Alain Carpentier | Flexible cardiac valvular support prosthesis |
| JP2810665B2 (en) | 1987-06-15 | 1998-10-15 | 松下電工株式会社 | Blood circulation promotion device |
| US4830023A (en) | 1987-11-27 | 1989-05-16 | Medi-Tech, Incorporated | Medical guidewire |
| US5099838A (en) * | 1988-12-15 | 1992-03-31 | Medtronic, Inc. | Endocardial defibrillation electrode system |
| JP2754067B2 (en) | 1989-01-17 | 1998-05-20 | 日本ゼオン株式会社 | Medical body wall hole plugging jig |
| US5350420A (en) | 1989-07-31 | 1994-09-27 | Baxter International Inc. | Flexible annuloplasty ring and holder |
| CA2026604A1 (en) * | 1989-10-02 | 1991-04-03 | Rodney G. Wolff | Articulated stent |
| US5454365A (en) | 1990-11-05 | 1995-10-03 | Bonutti; Peter M. | Mechanically expandable arthroscopic retractors |
| US5344426A (en) | 1990-04-25 | 1994-09-06 | Advanced Cardiovascular Systems, Inc. | Method and system for stent delivery |
| US6197059B1 (en) * | 1990-04-27 | 2001-03-06 | Medevec Licensing, B.V. | Accomodating intraocular lens |
| US5197978B1 (en) | 1991-04-26 | 1996-05-28 | Advanced Coronary Tech | Removable heat-recoverable tissue supporting device |
| US5261916A (en) | 1991-12-12 | 1993-11-16 | Target Therapeutics | Detachable pusher-vasoocclusive coil assembly with interlocking ball and keyway coupling |
| US5265601A (en) | 1992-05-01 | 1993-11-30 | Medtronic, Inc. | Dual chamber cardiac pacing from a single electrode |
| GB9213978D0 (en) * | 1992-07-01 | 1992-08-12 | Skidmore Robert | Medical devices |
| US5250071A (en) | 1992-09-22 | 1993-10-05 | Target Therapeutics, Inc. | Detachable embolic coil assembly using interlocking clasps and method of use |
| US5441515A (en) | 1993-04-23 | 1995-08-15 | Advanced Cardiovascular Systems, Inc. | Ratcheting stent |
| WO1994027670A1 (en) * | 1993-06-02 | 1994-12-08 | Cardiac Pathways Corporation | Catheter having tip with fixation means |
| FR2706309B1 (en) * | 1993-06-17 | 1995-10-06 | Sofamor | Instrument for surgical treatment of an intervertebral disc by the anterior route. |
| US5458615A (en) | 1993-07-06 | 1995-10-17 | Advanced Cardiovascular Systems, Inc. | Stent delivery system |
| US5411549A (en) | 1993-07-13 | 1995-05-02 | Scimed Life Systems, Inc. | Selectively expandable, retractable and removable stent |
| FR2710254B1 (en) | 1993-09-21 | 1995-10-27 | Mai Christian | Multi-branch osteosynthesis clip with self-retaining dynamic compression. |
| DE69419877T2 (en) | 1993-11-04 | 1999-12-16 | C.R. Bard, Inc. | Fixed vascular prosthesis |
| US5728122A (en) * | 1994-01-18 | 1998-03-17 | Datascope Investment Corp. | Guide wire with releaseable barb anchor |
| US5645560A (en) | 1995-12-15 | 1997-07-08 | Cardiovascular Dynamics, Inc. | Fixed focal balloon for interactive angioplasty and stent implantation |
| US5417708A (en) | 1994-03-09 | 1995-05-23 | Cook Incorporated | Intravascular treatment system and percutaneous release mechanism therefor |
| US5449373A (en) | 1994-03-17 | 1995-09-12 | Medinol Ltd. | Articulated stent |
| FR2718036B1 (en) | 1994-04-05 | 1996-08-30 | Ela Medical Sa | Method for controlling a triple atrial pacemaker of the triple chamber type. |
| FR2718035B1 (en) | 1994-04-05 | 1996-08-30 | Ela Medical Sa | Method for controlling a double atrial pacemaker of the triple chamber type programmable in fallback mode. |
| WO1995029646A1 (en) | 1994-04-29 | 1995-11-09 | Boston Scientific Corporation | Medical prosthetic stent and method of manufacture |
| US5617854A (en) * | 1994-06-22 | 1997-04-08 | Munsif; Anand | Shaped catheter device and method |
| US5433727A (en) | 1994-08-16 | 1995-07-18 | Sideris; Eleftherios B. | Centering buttoned device for the occlusion of large defects for occluding |
| US5899882A (en) | 1994-10-27 | 1999-05-04 | Novoste Corporation | Catheter apparatus for radiation treatment of a desired area in the vascular system of a patient |
| US5549662A (en) | 1994-11-07 | 1996-08-27 | Scimed Life Systems, Inc. | Expandable stent using sliding members |
| US5879366A (en) * | 1996-12-20 | 1999-03-09 | W.L. Gore & Associates, Inc. | Self-expanding defect closure device and method of making and using |
| US5575818A (en) | 1995-02-14 | 1996-11-19 | Corvita Corporation | Endovascular stent with locking ring |
| US5554177A (en) | 1995-03-27 | 1996-09-10 | Medtronic, Inc. | Method and apparatus to optimize pacing based on intensity of acoustic signal |
| US5693089A (en) | 1995-04-12 | 1997-12-02 | Inoue; Kanji | Method of collapsing an implantable appliance |
| AU4632196A (en) | 1995-04-14 | 1996-10-30 | Schneider (Usa) Inc. | Rolling membrane stent delivery device |
| US5601600A (en) | 1995-09-08 | 1997-02-11 | Conceptus, Inc. | Endoluminal coil delivery system having a mechanical release mechanism |
| EP0950385A3 (en) | 1995-12-14 | 1999-10-27 | Prograft Medical, Inc. | Stent-graft deployment apparatus and method |
| US6053900A (en) * | 1996-02-16 | 2000-04-25 | Brown; Joe E. | Apparatus and method for delivering diagnostic and therapeutic agents intravascularly |
| US5853422A (en) | 1996-03-22 | 1998-12-29 | Scimed Life Systems, Inc. | Apparatus and method for closing a septal defect |
| US5827293A (en) | 1996-05-13 | 1998-10-27 | Elliott; James B. | Subcutaneous insertion device |
| IL122904A0 (en) * | 1996-05-31 | 1998-08-16 | Bard Galway Ltd | Bifurcated endovascular stents and method and apparatus for their placement |
| CA2258732C (en) * | 1996-06-20 | 2006-04-04 | Sulzer Vascutek Ltd. | Prosthetic repair of body passages |
| US6077295A (en) | 1996-07-15 | 2000-06-20 | Advanced Cardiovascular Systems, Inc. | Self-expanding stent delivery system |
| US5741297A (en) * | 1996-08-28 | 1998-04-21 | Simon; Morris | Daisy occluder and method for septal defect repair |
| US5655548A (en) | 1996-09-16 | 1997-08-12 | Circulation, Inc. | Method for treatment of ischemic heart disease by providing transvenous myocardial perfusion |
| US6254628B1 (en) | 1996-12-09 | 2001-07-03 | Micro Therapeutics, Inc. | Intracranial stent |
| US5895391A (en) | 1996-09-27 | 1999-04-20 | Target Therapeutics, Inc. | Ball lock joint and introducer for vaso-occlusive member |
| US5868781A (en) * | 1996-10-22 | 1999-02-09 | Scimed Life Systems, Inc. | Locking stent |
| US6805128B1 (en) | 1996-10-22 | 2004-10-19 | Epicor Medical, Inc. | Apparatus and method for ablating tissue |
| US6395017B1 (en) | 1996-11-15 | 2002-05-28 | C. R. Bard, Inc. | Endoprosthesis delivery catheter with sequential stage control |
| US6352561B1 (en) | 1996-12-23 | 2002-03-05 | W. L. Gore & Associates | Implant deployment apparatus |
| IL119911A (en) * | 1996-12-25 | 2001-03-19 | Niti Alloys Tech Ltd | Surgical clip |
| US6050936A (en) | 1997-01-02 | 2000-04-18 | Myocor, Inc. | Heart wall tension reduction apparatus |
| US6045497A (en) * | 1997-01-02 | 2000-04-04 | Myocor, Inc. | Heart wall tension reduction apparatus and method |
| US5961545A (en) | 1997-01-17 | 1999-10-05 | Meadox Medicals, Inc. | EPTFE graft-stent composite device |
| US6241757B1 (en) * | 1997-02-04 | 2001-06-05 | Solco Surgical Instrument Co., Ltd. | Stent for expanding body's lumen |
| US5814064A (en) | 1997-03-06 | 1998-09-29 | Scimed Life Systems, Inc. | Distal protection device |
| US5800393A (en) * | 1997-03-07 | 1998-09-01 | Sahota; Harvinder | Wire perfusion catheter |
| JP4430744B2 (en) | 1997-03-14 | 2010-03-10 | ユニヴァーシティ・オヴ・アラバマ・アト・バーミンガム・リサーチ・ファンデイション | Implantable system for patients in need of such treatment with cardiac cardioversion |
| US6275730B1 (en) | 1997-03-14 | 2001-08-14 | Uab Research Foundation | Method and apparatus for treating cardiac arrythmia |
| US5836882A (en) | 1997-03-17 | 1998-11-17 | Frazin; Leon J. | Method and apparatus of localizing an insertion end of a probe within a biotic structure |
| US5954761A (en) | 1997-03-25 | 1999-09-21 | Intermedics Inc. | Implantable endocardial lead assembly having a stent |
| JP2002503991A (en) | 1997-06-13 | 2002-02-05 | マイクロ・テラピューティクス・インコーポレーテッド | Syringe and luer hub having novel shape and method of forming embolus |
| FR2766374B1 (en) | 1997-07-24 | 2000-01-28 | Medex Sa | DEVICE FOR INJECTING A LIQUID FOR MEDICAL SYRINGE ASSOCIATED WITH THE DEVICE AND METHOD FOR PLACING THE SYRINGE |
| US6007519A (en) | 1997-07-30 | 1999-12-28 | Rosselli; Matteo | Central access cannulation device |
| US5984944A (en) | 1997-09-12 | 1999-11-16 | B. Braun Medical, Inc. | Introducer for an expandable vascular occlusion device |
| US6096064A (en) | 1997-09-19 | 2000-08-01 | Intermedics Inc. | Four chamber pacer for dilated cardiomyopthy |
| ES2290995T3 (en) | 1997-09-24 | 2008-02-16 | Med Institute, Inc. | RADIALLY EXPANDABLE ENDOPROTESIS. |
| US6086611A (en) | 1997-09-25 | 2000-07-11 | Ave Connaught | Bifurcated stent |
| US5928258A (en) | 1997-09-26 | 1999-07-27 | Corvita Corporation | Method and apparatus for loading a stent or stent-graft into a delivery sheath |
| US6099552A (en) | 1997-11-12 | 2000-08-08 | Boston Scientific Corporation | Gastrointestinal copression clips |
| US6059775A (en) * | 1997-12-31 | 2000-05-09 | Nielsen; James M. | Multifocal corneal sculpturing |
| US6190406B1 (en) | 1998-01-09 | 2001-02-20 | Nitinal Development Corporation | Intravascular stent having tapered struts |
| US6342067B1 (en) * | 1998-01-09 | 2002-01-29 | Nitinol Development Corporation | Intravascular stent having curved bridges for connecting adjacent hoops |
| US6129755A (en) | 1998-01-09 | 2000-10-10 | Nitinol Development Corporation | Intravascular stent having an improved strut configuration |
| US6503271B2 (en) | 1998-01-09 | 2003-01-07 | Cordis Corporation | Intravascular device with improved radiopacity |
| US6345198B1 (en) * | 1998-01-23 | 2002-02-05 | Pacesetter, Inc. | Implantable stimulation system for providing dual bipolar sensing using an electrode positioned in proximity to the tricuspid valve and programmable polarity |
| WO1999039637A1 (en) | 1998-02-05 | 1999-08-12 | Mault James R | Metabolic calorimeter employing respiratory gas analysis |
| US6623521B2 (en) | 1998-02-17 | 2003-09-23 | Md3, Inc. | Expandable stent with sliding and locking radial elements |
| AU746955B2 (en) | 1998-03-27 | 2002-05-09 | Cook Urological Inc. | Minimally-invasive medical retrieval device |
| CA2333591C (en) * | 1998-06-02 | 2009-12-15 | Cook Incorporated | Multiple-sided intraluminal medical device |
| US6250308B1 (en) | 1998-06-16 | 2001-06-26 | Cardiac Concepts, Inc. | Mitral valve annuloplasty ring and method of implanting |
| NL1009551C2 (en) | 1998-07-03 | 2000-01-07 | Cordis Europ | Vena cava filter with improvements for controlled ejection. |
| US6228098B1 (en) | 1998-07-10 | 2001-05-08 | General Surgical Innovations, Inc. | Apparatus and method for surgical fastening |
| EP1112041A1 (en) * | 1998-09-10 | 2001-07-04 | Percardia, Inc. | Tmr shunt |
| US6458092B1 (en) * | 1998-09-30 | 2002-10-01 | C. R. Bard, Inc. | Vascular inducing implants |
| US6368345B1 (en) | 1998-09-30 | 2002-04-09 | Edwards Lifesciences Corporation | Methods and apparatus for intraluminal placement of a bifurcated intraluminal garafat |
| US6358276B1 (en) * | 1998-09-30 | 2002-03-19 | Impra, Inc. | Fluid containing endoluminal stent |
| US7044134B2 (en) | 1999-11-08 | 2006-05-16 | Ev3 Sunnyvale, Inc | Method of implanting a device in the left atrial appendage |
| US6214036B1 (en) | 1998-11-09 | 2001-04-10 | Cordis Corporation | Stent which is easily recaptured and repositioned within the body |
| WO2000030553A1 (en) | 1998-11-20 | 2000-06-02 | Medical Industries Corp. | Hemostatic agent inserting device |
| CN1212810C (en) | 1999-01-27 | 2005-08-03 | 维亚科公司 | Cardiac valve procedure methods and devices |
| BR0007932A (en) | 1999-02-01 | 2002-07-02 | Univ Texas | Bifurcated and trifurcated braided stents and methods for their manufacture |
| US7018401B1 (en) * | 1999-02-01 | 2006-03-28 | Board Of Regents, The University Of Texas System | Woven intravascular devices and methods for making the same and apparatus for delivery of the same |
| DE19910233A1 (en) | 1999-03-09 | 2000-09-21 | Jostra Medizintechnik Ag | Anuloplasty prosthesis |
| US6159220A (en) | 1999-03-11 | 2000-12-12 | Scimed Life Systems, Inc. | Medical retrieval device |
| CA2369641C (en) | 1999-04-09 | 2009-02-10 | Evalve, Inc. | Methods and apparatus for cardiac valve repair |
| US6183512B1 (en) * | 1999-04-16 | 2001-02-06 | Edwards Lifesciences Corporation | Flexible annuloplasty system |
| US6317615B1 (en) | 1999-04-19 | 2001-11-13 | Cardiac Pacemakers, Inc. | Method and system for reducing arterial restenosis in the presence of an intravascular stent |
| US6758830B1 (en) * | 1999-05-11 | 2004-07-06 | Atrionix, Inc. | Catheter positioning system |
| US6602289B1 (en) | 1999-06-08 | 2003-08-05 | S&A Rings, Llc | Annuloplasty rings of particular use in surgery for the mitral valve |
| US6626899B2 (en) | 1999-06-25 | 2003-09-30 | Nidus Medical, Llc | Apparatus and methods for treating tissue |
| SE514718C2 (en) | 1999-06-29 | 2001-04-09 | Jan Otto Solem | Apparatus for treating defective closure of the mitral valve apparatus |
| US7192442B2 (en) | 1999-06-30 | 2007-03-20 | Edwards Lifesciences Ag | Method and device for treatment of mitral insufficiency |
| US6997951B2 (en) | 1999-06-30 | 2006-02-14 | Edwards Lifesciences Ag | Method and device for treatment of mitral insufficiency |
| US6391038B2 (en) | 1999-07-28 | 2002-05-21 | Cardica, Inc. | Anastomosis system and method for controlling a tissue site |
| US7306618B2 (en) | 1999-07-30 | 2007-12-11 | Incept Llc | Vascular device for emboli and thrombi removal and methods of use |
| FR2799364B1 (en) * | 1999-10-12 | 2001-11-23 | Jacques Seguin | MINIMALLY INVASIVE CANCELING DEVICE |
| US6613075B1 (en) | 1999-10-27 | 2003-09-02 | Cordis Corporation | Rapid exchange self-expanding stent delivery catheter system |
| US6368284B1 (en) | 1999-11-16 | 2002-04-09 | Cardiac Intelligence Corporation | Automated collection and analysis patient care system and method for diagnosing and monitoring myocardial ischemia and outcomes thereof |
| US6556873B1 (en) * | 1999-11-29 | 2003-04-29 | Medtronic, Inc. | Medical electrical lead having variable bending stiffness |
| CN1243520C (en) | 2000-01-14 | 2006-03-01 | 维亚科公司 | Tissue annuloplasty band and apparatus and method for fashioning, sizing and implanting the same |
| US6402781B1 (en) * | 2000-01-31 | 2002-06-11 | Mitralife | Percutaneous mitral annuloplasty and cardiac reinforcement |
| US7507252B2 (en) | 2000-01-31 | 2009-03-24 | Edwards Lifesciences Ag | Adjustable transluminal annuloplasty system |
| US6989028B2 (en) | 2000-01-31 | 2006-01-24 | Edwards Lifesciences Ag | Medical system and method for remodeling an extravascular tissue structure |
| US6821297B2 (en) | 2000-02-02 | 2004-11-23 | Robert V. Snyders | Artificial heart valve, implantation instrument and method therefor |
| US6358195B1 (en) | 2000-03-09 | 2002-03-19 | Neoseed Technology Llc | Method and apparatus for loading radioactive seeds into brachytherapy needles |
| US6569198B1 (en) | 2000-03-31 | 2003-05-27 | Richard A. Wilson | Mitral or tricuspid valve annuloplasty prosthetic device |
| US6478776B1 (en) | 2000-04-05 | 2002-11-12 | Biocardia, Inc. | Implant delivery catheter system and methods for its use |
| DE60134907D1 (en) * | 2000-04-10 | 2008-09-04 | Seiko Epson Corp | Coating liquid, image recording method and a record produced therewith |
| US6442427B1 (en) | 2000-04-27 | 2002-08-27 | Medtronic, Inc. | Method and system for stimulating a mammalian heart |
| IL136213A0 (en) * | 2000-05-17 | 2001-05-20 | Xtent Medical Inc | Selectively expandable and releasable stent |
| US6334864B1 (en) * | 2000-05-17 | 2002-01-01 | Aga Medical Corp. | Alignment member for delivering a non-symmetric device with a predefined orientation |
| US6589208B2 (en) | 2000-06-20 | 2003-07-08 | Applied Medical Resources Corporation | Self-deploying catheter assembly |
| EP1330189B1 (en) | 2000-06-23 | 2007-12-19 | Viacor Incorporated | Automated annular plication for mitral valve repair |
| AU2001273088A1 (en) | 2000-06-30 | 2002-01-30 | Viacor Incorporated | Intravascular filter with debris entrapment mechanism |
| AU2001271667A1 (en) | 2000-06-30 | 2002-01-14 | Viacor Incorporated | Method and apparatus for performing a procedure on a cardiac valve |
| US6419696B1 (en) | 2000-07-06 | 2002-07-16 | Paul A. Spence | Annuloplasty devices and related heart valve repair methods |
| JP2002035135A (en) | 2000-07-31 | 2002-02-05 | Manii Kk | Stent and method for manufacturing stent |
| US6743219B1 (en) * | 2000-08-02 | 2004-06-01 | Cordis Corporation | Delivery apparatus for a self-expanding stent |
| US6846325B2 (en) | 2000-09-07 | 2005-01-25 | Viacor, Inc. | Fixation band for affixing a prosthetic heart valve to tissue |
| US20060106456A9 (en) | 2002-10-01 | 2006-05-18 | Ample Medical, Inc. | Devices, systems, and methods for reshaping a heart valve annulus |
| US6602288B1 (en) | 2000-10-05 | 2003-08-05 | Edwards Lifesciences Corporation | Minimally-invasive annuloplasty repair segment delivery template, system and method of use |
| US6723038B1 (en) | 2000-10-06 | 2004-04-20 | Myocor, Inc. | Methods and devices for improving mitral valve function |
| US6913608B2 (en) | 2000-10-23 | 2005-07-05 | Viacor, Inc. | Automated annular plication for mitral valve repair |
| US7070618B2 (en) | 2000-10-25 | 2006-07-04 | Viacor, Inc. | Mitral shield |
| WO2002034118A2 (en) | 2000-10-27 | 2002-05-02 | Viacor, Inc. | Intracardiovascular access (icvatm) system |
| DE10058730A1 (en) * | 2000-11-25 | 2003-01-02 | Buhler Motor Gmbh | Adjustment device for motor vehicle exterior mirrors |
| AU2002236640A1 (en) | 2000-12-15 | 2002-06-24 | Viacor, Inc. | Apparatus and method for replacing aortic valve |
| US7591826B2 (en) | 2000-12-28 | 2009-09-22 | Cardiac Dimensions, Inc. | Device implantable in the coronary sinus to provide mitral valve therapy |
| US7510576B2 (en) * | 2001-01-30 | 2009-03-31 | Edwards Lifesciences Ag | Transluminal mitral annuloplasty |
| JP4195612B2 (en) | 2001-01-30 | 2008-12-10 | エドワーズ ライフサイエンシーズ アーゲー | Medical system and method for improving extracorporeal tissue structure |
| US6810882B2 (en) | 2001-01-30 | 2004-11-02 | Ev3 Santa Rosa, Inc. | Transluminal mitral annuloplasty |
| WO2002062408A2 (en) | 2001-02-05 | 2002-08-15 | Viacor, Inc. | Method and apparatus for improving mitral valve function |
| US6790231B2 (en) | 2001-02-05 | 2004-09-14 | Viacor, Inc. | Apparatus and method for reducing mitral regurgitation |
| US6643546B2 (en) | 2001-02-13 | 2003-11-04 | Quetzal Biomedical, Inc. | Multi-electrode apparatus and method for treatment of congestive heart failure |
| US6562066B1 (en) * | 2001-03-02 | 2003-05-13 | Eric C. Martin | Stent for arterialization of the coronary sinus and retrograde perfusion of the myocardium |
| JP3468755B2 (en) | 2001-03-05 | 2003-11-17 | 石川島播磨重工業株式会社 | LCD drive board inspection equipment |
| CA2441370C (en) * | 2001-03-05 | 2011-05-24 | Viacor, Incorporated | Apparatus and method for reducing mitral regurgitation |
| US6955689B2 (en) | 2001-03-15 | 2005-10-18 | Medtronic, Inc. | Annuloplasty band and method |
| US6899734B2 (en) * | 2001-03-23 | 2005-05-31 | Howmedica Osteonics Corp. | Modular implant for fusing adjacent bone structure |
| WO2002076284A2 (en) | 2001-03-23 | 2002-10-03 | Viacor, Inc. | Method and apparatus for reducing mitral regurgitation |
| US7186264B2 (en) | 2001-03-29 | 2007-03-06 | Viacor, Inc. | Method and apparatus for improving mitral valve function |
| WO2002078576A2 (en) | 2001-03-29 | 2002-10-10 | Viacor, Inc. | Method and apparatus for improving mitral valve function |
| US6733521B2 (en) * | 2001-04-11 | 2004-05-11 | Trivascular, Inc. | Delivery system and method for endovascular graft |
| US6619291B2 (en) | 2001-04-24 | 2003-09-16 | Edwin J. Hlavka | Method and apparatus for catheter-based annuloplasty |
| US20020188170A1 (en) | 2001-04-27 | 2002-12-12 | Santamore William P. | Prevention of myocardial infarction induced ventricular expansion and remodeling |
| US6676692B2 (en) | 2001-04-27 | 2004-01-13 | Intek Technology L.L.C. | Apparatus for delivering, repositioning and/or retrieving self-expanding stents |
| US6800090B2 (en) * | 2001-05-14 | 2004-10-05 | Cardiac Dimensions, Inc. | Mitral valve therapy device, system and method |
| US6676702B2 (en) | 2001-05-14 | 2004-01-13 | Cardiac Dimensions, Inc. | Mitral valve therapy assembly and method |
| US6599314B2 (en) | 2001-06-08 | 2003-07-29 | Cordis Corporation | Apparatus and method for stenting a vessel using balloon-actuated stent with interlocking elements |
| US6629994B2 (en) | 2001-06-11 | 2003-10-07 | Advanced Cardiovascular Systems, Inc. | Intravascular stent |
| US6783538B2 (en) | 2001-06-18 | 2004-08-31 | Rex Medical, L.P | Removable vein filter |
| DE10133063B4 (en) * | 2001-07-07 | 2005-08-04 | Itw Automotive Products Gmbh & Co. Kg | Fastening device and fastening element |
| US20030078654A1 (en) | 2001-08-14 | 2003-04-24 | Taylor Daniel C. | Method and apparatus for improving mitral valve function |
| US6908482B2 (en) * | 2001-08-28 | 2005-06-21 | Edwards Lifesciences Corporation | Three-dimensional annuloplasty ring and template |
| US6721598B1 (en) * | 2001-08-31 | 2004-04-13 | Pacesetter, Inc. | Coronary sinus cardiac lead for stimulating and sensing in the right and left heart and system |
| US6776784B2 (en) | 2001-09-06 | 2004-08-17 | Core Medical, Inc. | Clip apparatus for closing septal defects and methods of use |
| ES2310609T3 (en) | 2001-09-07 | 2009-01-16 | Mardil, Inc. | METHOD AND APPARATUS FOR THE EXTERNAL STABILIZATION OF THE HEART. |
| US7144363B2 (en) | 2001-10-16 | 2006-12-05 | Extensia Medical, Inc. | Systems for heart treatment |
| AUPR847301A0 (en) | 2001-10-26 | 2001-11-15 | Cook Incorporated | Endoluminal prostheses for curved lumens |
| US7052487B2 (en) | 2001-10-26 | 2006-05-30 | Cohn William E | Method and apparatus for reducing mitral regurgitation |
| US6949122B2 (en) | 2001-11-01 | 2005-09-27 | Cardiac Dimensions, Inc. | Focused compression mitral valve device and method |
| US6824562B2 (en) | 2002-05-08 | 2004-11-30 | Cardiac Dimensions, Inc. | Body lumen device anchor, device and assembly |
| US7635387B2 (en) * | 2001-11-01 | 2009-12-22 | Cardiac Dimensions, Inc. | Adjustable height focal tissue deflector |
| US7311729B2 (en) | 2002-01-30 | 2007-12-25 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
| US6805710B2 (en) * | 2001-11-13 | 2004-10-19 | Edwards Lifesciences Corporation | Mitral valve annuloplasty ring for molding left ventricle geometry |
| US6908478B2 (en) | 2001-12-05 | 2005-06-21 | Cardiac Dimensions, Inc. | Anchor and pull mitral valve device and method |
| US7179282B2 (en) | 2001-12-05 | 2007-02-20 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
| US6976995B2 (en) * | 2002-01-30 | 2005-12-20 | Cardiac Dimensions, Inc. | Fixed length anchor and pull mitral valve device and method |
| US6793673B2 (en) | 2002-12-26 | 2004-09-21 | Cardiac Dimensions, Inc. | System and method to effect mitral valve annulus of a heart |
| DE10161543B4 (en) | 2001-12-11 | 2004-02-19 | REITAN, Öyvind | Implant for the treatment of heart valve insufficiency |
| SE524709C2 (en) | 2002-01-11 | 2004-09-21 | Edwards Lifesciences Ag | Device for delayed reshaping of a heart vessel and a heart valve |
| US8075616B2 (en) | 2001-12-28 | 2011-12-13 | Edwards Lifesciences Ag | Apparatus for applying a compressive load on body tissue |
| US6764510B2 (en) | 2002-01-09 | 2004-07-20 | Myocor, Inc. | Devices and methods for heart valve treatment |
| WO2003105670A2 (en) * | 2002-01-10 | 2003-12-24 | Guided Delivery Systems, Inc. | Devices and methods for heart valve repair |
| US20050209690A1 (en) * | 2002-01-30 | 2005-09-22 | Mathis Mark L | Body lumen shaping device with cardiac leads |
| US6960229B2 (en) | 2002-01-30 | 2005-11-01 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
| US7351260B2 (en) | 2005-01-20 | 2008-04-01 | Cardiac Dimensions, Inc. | Tissue shaping device |
| US7125420B2 (en) * | 2002-02-05 | 2006-10-24 | Viacor, Inc. | Method and apparatus for improving mitral valve function |
| US7004958B2 (en) | 2002-03-06 | 2006-02-28 | Cardiac Dimensions, Inc. | Transvenous staples, assembly and method for mitral valve repair |
| US6797001B2 (en) * | 2002-03-11 | 2004-09-28 | Cardiac Dimensions, Inc. | Device, assembly and method for mitral valve repair |
| US20030199974A1 (en) * | 2002-04-18 | 2003-10-23 | Coalescent Surgical, Inc. | Annuloplasty apparatus and methods |
| CA2744868C (en) | 2002-05-08 | 2015-12-29 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
| US20040243227A1 (en) | 2002-06-13 | 2004-12-02 | Guided Delivery Systems, Inc. | Delivery devices and methods for heart valve repair |
| US8287555B2 (en) | 2003-02-06 | 2012-10-16 | Guided Delivery Systems, Inc. | Devices and methods for heart valve repair |
| ATE464028T1 (en) | 2002-08-29 | 2010-04-15 | St Jude Medical Cardiology Div | IMPLANTABLE DEVICES FOR CONTROLLING THE INNER DIAMETER OF AN OPENING IN THE BODY |
| US7087064B1 (en) | 2002-10-15 | 2006-08-08 | Advanced Cardiovascular Systems, Inc. | Apparatuses and methods for heart valve repair |
| US7247134B2 (en) | 2002-11-12 | 2007-07-24 | Myocor, Inc. | Devices and methods for heart valve treatment |
| US7112219B2 (en) | 2002-11-12 | 2006-09-26 | Myocor, Inc. | Devices and methods for heart valve treatment |
| US20040098116A1 (en) * | 2002-11-15 | 2004-05-20 | Callas Peter L. | Valve annulus constriction apparatus and method |
| US7485143B2 (en) | 2002-11-15 | 2009-02-03 | Abbott Cardiovascular Systems Inc. | Apparatuses and methods for heart valve repair |
| US7316708B2 (en) * | 2002-12-05 | 2008-01-08 | Cardiac Dimensions, Inc. | Medical device delivery system |
| US7837729B2 (en) * | 2002-12-05 | 2010-11-23 | Cardiac Dimensions, Inc. | Percutaneous mitral valve annuloplasty delivery system |
| US20040133240A1 (en) | 2003-01-07 | 2004-07-08 | Cardiac Dimensions, Inc. | Electrotherapy system, device, and method for treatment of cardiac valve dysfunction |
| US7314485B2 (en) | 2003-02-03 | 2008-01-01 | Cardiac Dimensions, Inc. | Mitral valve device using conditioned shape memory alloy |
| US20040158321A1 (en) | 2003-02-12 | 2004-08-12 | Cardiac Dimensions, Inc. | Method of implanting a mitral valve therapy device |
| SE0300854D0 (en) | 2003-03-26 | 2003-03-26 | Oeyvind Reitan | Device for the treatment of a heart valve insufficiency |
| US20060161169A1 (en) | 2003-05-02 | 2006-07-20 | Cardiac Dimensions, Inc., A Delaware Corporation | Device and method for modifying the shape of a body organ |
| US20040220654A1 (en) | 2003-05-02 | 2004-11-04 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
| US20040220657A1 (en) | 2003-05-02 | 2004-11-04 | Cardiac Dimensions, Inc., A Washington Corporation | Tissue shaping device with conformable anchors |
| DE102004025323A1 (en) * | 2003-05-23 | 2005-02-17 | Siempelkamp Maschinen- Und Anlagenbau Gmbh & Co. Kg | Comminuting apparatus for stack of wooden boards used in producing wood strands has replaceable filler bodies provided in the chamber to which a blade ring is disposed to reduce free space |
| US7351259B2 (en) | 2003-06-05 | 2008-04-01 | Cardiac Dimensions, Inc. | Device, system and method to affect the mitral valve annulus of a heart |
| US7887582B2 (en) | 2003-06-05 | 2011-02-15 | Cardiac Dimensions, Inc. | Device and method for modifying the shape of a body organ |
| US20040260384A1 (en) | 2003-06-17 | 2004-12-23 | Medtronic Ave | Superelastic coiled stent |
| EP1646332B1 (en) * | 2003-07-18 | 2015-06-17 | Edwards Lifesciences AG | Remotely activated mitral annuloplasty system |
| US7004176B2 (en) | 2003-10-17 | 2006-02-28 | Edwards Lifesciences Ag | Heart valve leaflet locator |
| WO2005046530A1 (en) | 2003-11-12 | 2005-05-26 | Medtronic Vascular, Inc. | Coronary sinus approach for repair of mitral valve reguritation |
| US7955384B2 (en) * | 2003-11-12 | 2011-06-07 | Medtronic Vascular, Inc. | Coronary sinus approach for repair of mitral valve regurgitation |
| WO2005058206A1 (en) | 2003-12-16 | 2005-06-30 | Edwards Lifesciences Ag | Device for changing the shape of the mitral annulus |
| US20050177228A1 (en) | 2003-12-16 | 2005-08-11 | Solem Jan O. | Device for changing the shape of the mitral annulus |
| US9526616B2 (en) | 2003-12-19 | 2016-12-27 | Cardiac Dimensions Pty. Ltd. | Mitral valve annuloplasty device with twisted anchor |
| US20060271174A1 (en) | 2003-12-19 | 2006-11-30 | Gregory Nieminen | Mitral Valve Annuloplasty Device with Wide Anchor |
| US7794496B2 (en) | 2003-12-19 | 2010-09-14 | Cardiac Dimensions, Inc. | Tissue shaping device with integral connector and crimp |
| US7837728B2 (en) | 2003-12-19 | 2010-11-23 | Cardiac Dimensions, Inc. | Reduced length tissue shaping device |
| US20050137449A1 (en) * | 2003-12-19 | 2005-06-23 | Cardiac Dimensions, Inc. | Tissue shaping device with self-expanding anchors |
| US20050137450A1 (en) * | 2003-12-19 | 2005-06-23 | Cardiac Dimensions, Inc., A Washington Corporation | Tapered connector for tissue shaping device |
| WO2005087139A1 (en) * | 2004-03-15 | 2005-09-22 | Baker Medical Research Institute | Treating valve failure |
| US7993397B2 (en) | 2004-04-05 | 2011-08-09 | Edwards Lifesciences Ag | Remotely adjustable coronary sinus implant |
| EP1781179A1 (en) | 2004-07-06 | 2007-05-09 | Baker Medical Research Institute | Treating valvular insufficiency |
| US20070027533A1 (en) | 2005-07-28 | 2007-02-01 | Medtronic Vascular, Inc. | Cardiac valve annulus restraining device |
| US20080221673A1 (en) | 2005-08-12 | 2008-09-11 | Donald Bobo | Medical implant with reinforcement mechanism |
| US20070055879A1 (en) * | 2005-08-16 | 2007-03-08 | Jianjun Luo | System and method for high performance public key encryption |
| US20070073391A1 (en) | 2005-09-28 | 2007-03-29 | Henry Bourang | System and method for delivering a mitral valve repair device |
| WO2007067820A2 (en) | 2005-12-09 | 2007-06-14 | Edwards Lifesciences Corporation | Improved anchoring system for medical implant |
| US7503932B2 (en) | 2006-04-11 | 2009-03-17 | Cardiac Dimensions, Inc. | Mitral valve annuloplasty device with vena cava anchor |
| US8006594B2 (en) | 2008-08-11 | 2011-08-30 | Cardiac Dimensions, Inc. | Catheter cutting tool |
-
2002
- 2002-01-30 US US10/066,426 patent/US6976995B2/en not_active Expired - Lifetime
-
2003
- 2003-01-22 AU AU2003211731A patent/AU2003211731B2/en not_active Expired
- 2003-01-22 ES ES15190348.1T patent/ES2636661T3/en not_active Expired - Lifetime
- 2003-01-22 ES ES03734987.5T patent/ES2558860T3/en not_active Expired - Lifetime
- 2003-01-22 EP EP17170256.6A patent/EP3254644B1/en not_active Expired - Lifetime
- 2003-01-22 CA CA2469460A patent/CA2469460C/en not_active Expired - Lifetime
- 2003-01-22 ES ES17170256T patent/ES2749598T3/en not_active Expired - Lifetime
- 2003-01-22 JP JP2003563433A patent/JP4359660B2/en not_active Expired - Fee Related
- 2003-01-22 EP EP15190348.1A patent/EP3011931B1/en not_active Expired - Lifetime
- 2003-01-22 WO PCT/US2003/002124 patent/WO2003063735A2/en active Application Filing
- 2003-01-22 CA CA2760865A patent/CA2760865C/en not_active Expired - Lifetime
- 2003-01-22 EP EP03734987.5A patent/EP1482869B1/en not_active Expired - Lifetime
-
2005
- 2005-05-18 US US11/132,788 patent/US20050216077A1/en not_active Abandoned
-
2008
- 2008-01-17 US US12/016,054 patent/US9408695B2/en not_active Expired - Fee Related
- 2008-04-01 US US12/060,781 patent/US7828842B2/en not_active Expired - Lifetime
-
2010
- 2010-10-19 US US12/907,907 patent/US8974525B2/en not_active Expired - Lifetime
-
2015
- 2015-03-09 US US14/642,476 patent/US9320600B2/en active Active
-
2016
- 2016-04-22 US US15/136,739 patent/US9597186B2/en active Active
- 2016-08-05 US US15/230,093 patent/US10052205B2/en not_active Expired - Fee Related
- 2016-08-05 US US15/230,060 patent/US9827098B2/en not_active Expired - Lifetime
- 2016-09-09 US US15/261,549 patent/US9827099B2/en not_active Expired - Lifetime
- 2016-09-09 US US15/261,572 patent/US9956076B2/en not_active Expired - Lifetime
- 2016-09-09 US US15/261,594 patent/US9827100B2/en not_active Expired - Lifetime
-
2017
- 2017-03-21 US US15/465,253 patent/US10206778B2/en active Active
-
2018
- 2018-05-01 US US15/968,612 patent/US10327900B2/en not_active Expired - Fee Related
-
2019
- 2019-06-24 US US16/450,686 patent/US20190336290A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10327900B2 (en) | Tissue shaping device | |
| AU2003211731A1 (en) | Fixed length anchor and pull mitral valve device and method | |
| EP1450733B1 (en) | Anchor and pull mitral valve device and method | |
| US6797001B2 (en) | Device, assembly and method for mitral valve repair | |
| JP2005515833A5 (en) |