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AU2002229859B2 - Chemical derivatives and their use as anti-telomerase agent - Google Patents

Chemical derivatives and their use as anti-telomerase agent Download PDF

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Publication number
AU2002229859B2
AU2002229859B2 AU2002229859A AU2002229859A AU2002229859B2 AU 2002229859 B2 AU2002229859 B2 AU 2002229859B2 AU 2002229859 A AU2002229859 A AU 2002229859A AU 2002229859 A AU2002229859 A AU 2002229859A AU 2002229859 B2 AU2002229859 B2 AU 2002229859B2
Authority
AU
Australia
Prior art keywords
group
alkyl
carbon atoms
compound according
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
AU2002229859A
Other languages
English (en)
Other versions
AU2002229859A1 (en
Inventor
Marcel Alasia
Thomas Caulfield
Gilles Doerflinger
Abdelazize Laoui
Patrick Mailliet
Jean-Louis Mergny
Odile Petitgenet
Emmanuelle Renou
Jean-Francois Riou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of AU2002229859A1 publication Critical patent/AU2002229859A1/en
Application granted granted Critical
Publication of AU2002229859B2 publication Critical patent/AU2002229859B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2002229859A 2001-01-09 2002-01-09 Chemical derivatives and their use as anti-telomerase agent Expired - Fee Related AU2002229859B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR01/00205 2001-01-09
FR0100205A FR2819255B1 (fr) 2001-01-09 2001-01-09 Derives chimiques et leur application comme agent antitelomerase
PCT/FR2002/000057 WO2002055515A1 (fr) 2001-01-09 2002-01-09 Derives chimiques et leur application comme agent antitelomerase

Publications (2)

Publication Number Publication Date
AU2002229859A1 AU2002229859A1 (en) 2003-02-06
AU2002229859B2 true AU2002229859B2 (en) 2008-03-13

Family

ID=8858610

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002229859A Expired - Fee Related AU2002229859B2 (en) 2001-01-09 2002-01-09 Chemical derivatives and their use as anti-telomerase agent

Country Status (8)

Country Link
EP (1) EP1351957A1 (fr)
JP (1) JP2004520350A (fr)
AU (1) AU2002229859B2 (fr)
CA (1) CA2433723A1 (fr)
FR (1) FR2819255B1 (fr)
IL (1) IL156794A0 (fr)
MX (1) MXPA03005975A (fr)
WO (1) WO2002055515A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6887873B2 (en) 2001-03-23 2005-05-03 Aventis Pharma S.A. Triazine derivatives and their application as antitelomerase agents
US7173032B2 (en) * 2001-09-21 2007-02-06 Reddy Us Therapeutics, Inc. Methods and compositions of novel triazine compounds
FR2850970B1 (fr) * 2003-02-07 2006-07-07 Aventis Pharma Sa Derives chimiques se liant de maniere tres specifique aux structures d'adn en g-quadruplexe et leur application comme agent anticancereux specifique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9206768D0 (en) * 1992-03-27 1992-05-13 Jarman Michael New compounds for use in the treatment of cancer
US5767278A (en) * 1995-10-06 1998-06-16 Geron Corporation Telomerase inhibitors
JPH1160573A (ja) * 1997-08-22 1999-03-02 Nippon Kayaku Co Ltd トリアジン誘導体及びテロメラーゼ阻害剤

Also Published As

Publication number Publication date
EP1351957A1 (fr) 2003-10-15
WO2002055515A1 (fr) 2002-07-18
IL156794A0 (en) 2004-02-08
FR2819255B1 (fr) 2003-02-28
CA2433723A1 (fr) 2002-07-18
FR2819255A1 (fr) 2002-07-12
MXPA03005975A (es) 2005-02-14
JP2004520350A (ja) 2004-07-08

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Legal Events

Date Code Title Description
MK25 Application lapsed reg. 22.2i(2) - failure to pay acceptance fee