|
TWI321054B
(en)
*
|
2000-12-19 |
2010-03-01 |
California Inst Of Techn |
Compositions containing inclusion complexes
|
|
CA2465860A1
(en)
*
|
2001-11-02 |
2004-04-22 |
Insert Therapeutics, Inc. |
Methods and compositions for therapeutic use of rna interference
|
|
US20040063654A1
(en)
*
|
2001-11-02 |
2004-04-01 |
Davis Mark E. |
Methods and compositions for therapeutic use of RNA interference
|
|
JP2005514438A
(en)
|
2001-12-21 |
2005-05-19 |
ソーン， デイビッド エス． |
Use of oligomers and polymers for solubilization, stabilization and delivery of drugs
|
|
BRPI0314042B8
(en)
|
2002-09-06 |
2021-05-25 |
Calando Pharmaceuticals Inc |
cyclodextrin-based polymers for the delivery of covalently linked therapeutic agents
|
|
US20040220153A1
(en)
*
|
2002-09-24 |
2004-11-04 |
Jost-Price Edward Roydon |
Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
|
|
BR0315198A
(en)
*
|
2002-10-09 |
2005-08-30 |
Insert Therapeutics Inc |
Cyclodextrin-based materials and compositions and uses thereof
|
|
CA2518475C
(en)
|
2003-03-07 |
2014-12-23 |
Alnylam Pharmaceuticals, Inc. |
Irna agents comprising asymmetrical modifications
|
|
US20070179100A1
(en)
*
|
2003-04-09 |
2007-08-02 |
Muthiah Manoharan |
Protected monomers
|
|
WO2004094345A2
(en)
|
2003-04-17 |
2004-11-04 |
Alnylam Pharmaceuticals Inc. |
Protected monomers
|
|
US7851615B2
(en)
*
|
2003-04-17 |
2010-12-14 |
Alnylam Pharmaceuticals, Inc. |
Lipophilic conjugated iRNA agents
|
|
CA2522637C
(en)
*
|
2003-04-17 |
2014-01-21 |
Alnylam Pharmaceuticals, Inc. |
Modified irna agents
|
|
US7723509B2
(en)
|
2003-04-17 |
2010-05-25 |
Alnylam Pharmaceuticals |
IRNA agents with biocleavable tethers
|
|
US8017762B2
(en)
*
|
2003-04-17 |
2011-09-13 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
|
US8796436B2
(en)
|
2003-04-17 |
2014-08-05 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
|
JP4535229B2
(en)
*
|
2003-05-08 |
2010-09-01 |
国立大学法人 東京大学 |
Polyethylene glycol-polycation block copolymer
|
|
WO2005004794A2
(en)
|
2003-06-09 |
2005-01-20 |
Alnylam Pharmaceuticals Inc. |
Method of treating neurodegenerative disease
|
|
US7595306B2
(en)
*
|
2003-06-09 |
2009-09-29 |
Alnylam Pharmaceuticals Inc |
Method of treating neurodegenerative disease
|
|
KR100554156B1
(en)
*
|
2003-07-26 |
2006-02-22 |
학교법인 포항공과대학교 |
Nano-particles comprising curcurbituril derivatives, pharmaceutical composition containing the same, and process for the preparation thereof
|
|
KR100988321B1
(en)
*
|
2003-07-26 |
2010-10-18 |
포항공과대학교 산학협력단 |
Polymer comprising cucurbiturils, stationary phase and column using the same
|
|
TW200517114A
(en)
|
2003-10-15 |
2005-06-01 |
Combinatorx Inc |
Methods and reagents for the treatment of immunoinflammatory disorders
|
|
WO2005051174A2
(en)
*
|
2003-11-21 |
2005-06-09 |
The Trustees Of Columbia University In The City Of New York |
Nucleic acid aptamer-based compositions and methods
|
|
JP4692983B2
(en)
*
|
2004-07-12 |
2011-06-01 |
独立行政法人科学技術振興機構 |
Liposomes from which liposome encapsulated material can escape from endosomes
|
|
TW200612993A
(en)
*
|
2004-10-08 |
2006-05-01 |
Alza Corp |
Lipopolymer conjugates
|
|
US7883688B2
(en)
*
|
2005-02-03 |
2011-02-08 |
Agency For Science, Technology And Research |
Polycationic polyrotaxanes capable of forming complexes with nucleic acids
|
|
TW200640493A
(en)
*
|
2005-02-16 |
2006-12-01 |
Insert Therapeutics Inc |
Cyclodextrin-based polymers for therapeutics delivery
|
|
ES2381201T3
(en)
|
2005-03-31 |
2012-05-24 |
Calando Pharmaceuticals, Inc. |
Inhibitors of the subunit 2 of the ribonucleotide reductase and uses thereof
|
|
JP2007006849A
(en)
*
|
2005-07-04 |
2007-01-18 |
Japan Science & Technology Agency |
Nucleic acid transfection agent consisting of 6-amino-6-deoxychitosan derivative
|
|
JP5086254B2
(en)
|
2005-07-07 |
2012-11-28 |
フルクルム エスピー リミテッド |
SP1 polypeptides, modified SP1 polypeptides and uses thereof
|
|
KR100642220B1
(en)
*
|
2005-07-12 |
2006-11-03 |
광주과학기술원 |
Conjugates of cyclodextrin and poly(oxyethylene) and process for preparation thereof
|
|
US20070021380A1
(en)
*
|
2005-07-22 |
2007-01-25 |
Leonard Wiebe |
Novel drug delivery compositions
|
|
EP1940391A4
(en)
*
|
2005-08-05 |
2010-01-20 |
Orbus Pharma Inc |
Stabilized extended release pharmeceutical compositions comprising an hmg-coa reductase inhibitor
|
|
AU2006308765B2
(en)
|
2005-11-02 |
2013-09-05 |
Arbutus Biopharma Corporation |
Modified siRNA molecules and uses thereof
|
|
US20090247603A1
(en)
*
|
2005-12-23 |
2009-10-01 |
Orbus Pharma, Inc. |
Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor
|
|
JP2007217376A
(en)
*
|
2006-02-17 |
2007-08-30 |
Nagoya Institute Of Technology |
Self-assembly peptide composition
|
|
KR100751540B1
(en)
*
|
2006-06-07 |
2007-08-22 |
재단법인서울대학교산학협력재단 |
Carcerands, carceplexes and guest-paired caceroisomers and molecular electronics using them
|
|
US9744137B2
(en)
*
|
2006-08-31 |
2017-08-29 |
Supernus Pharmaceuticals, Inc. |
Topiramate compositions and methods of enhancing its bioavailability
|
|
WO2008061226A2
(en)
|
2006-11-17 |
2008-05-22 |
Supernus Pharmaceuticals Inc. |
Sustained-release formulations of topiramate
|
|
WO2008070670A2
(en)
*
|
2006-12-04 |
2008-06-12 |
Supernus Pharmaceuticals, Inc. |
Enhanced immediate release formulations of topiramate
|
|
EP2121030A4
(en)
*
|
2007-01-17 |
2013-06-19 |
Immunomedics Inc |
Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites
|
|
US20080176958A1
(en)
|
2007-01-24 |
2008-07-24 |
Insert Therapeutics, Inc. |
Cyclodextrin-based polymers for therapeutics delivery
|
|
US8974814B2
(en)
*
|
2007-11-12 |
2015-03-10 |
California Institute Of Technology |
Layered drug delivery polymer monofilament fibers
|
|
WO2009079399A2
(en)
*
|
2007-12-14 |
2009-06-25 |
Alnylam Pharmaceuticals, Inc. |
Method of treating neurodegenerative disease
|
|
ES2535419T3
(en)
|
2007-12-27 |
2015-05-11 |
Protiva Biotherapeutics Inc. |
Polo kinase expression silencing using interfering RNA
|
|
JP5250796B2
(en)
*
|
2008-03-06 |
2013-07-31 |
株式会社不二製作所 |
Method for producing gel abrasive and gel abrasive
|
|
CA2720473A1
(en)
|
2008-04-04 |
2009-10-08 |
Calando Pharmaceuticals, Inc. |
Compositions and use of epas1 inhibitors
|
|
EP2770057A1
(en)
|
2008-04-15 |
2014-08-27 |
Protiva Biotherapeutics Inc. |
Silencing of CSN5 gene expression using interfering RNA
|
|
IL192262A
(en)
|
2008-06-17 |
2016-05-31 |
Z H T Eng Equipment And Tech Ltd |
Polymer adapted to release bioactive agents in vivo, pharmaceutical composition comprising it and method of preparation thereof
|
|
US20110223665A1
(en)
*
|
2008-07-25 |
2011-09-15 |
Alnylam Pharmaceuticals, Inc. |
ENHANCEMENT OF siRNA SILENCING ACTIVITY USING UNIVERSAL BASES OR MISMATCHES IN THE SENSE STRAND
|
|
KR101661746B1
(en)
*
|
2008-08-13 |
2016-09-30 |
캘리포니아 인스티튜트 오브 테크놀로지 |
Carrier nanoparticles and related compositions, methods and systems
|
|
US20100168044A1
(en)
*
|
2008-12-26 |
2010-07-01 |
Devesh Kumar Misra |
Superparamagnetic nanoparticle encapsulated with stimuli responsive polymer for drug delivery
|
|
US8309530B2
(en)
*
|
2009-02-04 |
2012-11-13 |
Washington State University |
Compositions and methods for modulating ghrelin-mediated conditions
|
|
WO2010138802A2
(en)
|
2009-05-28 |
2010-12-02 |
Cornell University |
Compositions and their use for removing cholesterol
|
|
ES2337226B2
(en)
*
|
2009-12-16 |
2011-09-14 |
Universidad De Granada |
LIPID SYSTEMS FUNCTIONED WITH VINYLSULPHONES. SYNTHESIS AND USES.
|
|
EP2515946B1
(en)
|
2009-12-23 |
2019-05-22 |
The Board of Trustees of the University of Illionis |
Nanoconjugates and nanoconjugate formulations
|
|
WO2011097138A1
(en)
*
|
2010-02-04 |
2011-08-11 |
Rgo Bioscience Llc |
Molecular entities for binding, stabilization and cellular delivery of negatively charged molecules
|
|
CN106036793B
(en)
*
|
2010-03-13 |
2020-11-06 |
伊斯顿庞德实验室有限公司 |
Fat-binding compositions
|
|
US8349308B2
(en)
|
2010-03-26 |
2013-01-08 |
Mersana Therapeutics, Inc. |
Modified polymers for delivery of polynucleotides, method of manufacture, and methods of use thereof
|
|
JP2013530187A
(en)
|
2010-06-17 |
2013-07-25 |
ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンティッド バイ ザ シークレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
Compositions and methods for treating inflammatory diseases.
|
|
WO2012005368A1
(en)
|
2010-07-08 |
2012-01-12 |
株式会社ボナック |
Single-strand nucleic acid molecule for controlling gene expression
|
|
EP2628801B1
(en)
|
2010-08-03 |
2015-01-07 |
Bonac Corporation |
Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton
|
|
US20130210663A1
(en)
|
2010-08-04 |
2013-08-15 |
Cizzle Biotechnology Limited |
Methods and compounds for the diagnosis and treatment of cancer
|
|
US9572895B2
(en)
|
2010-08-06 |
2017-02-21 |
The Board Of Trustees Of The University Of Illinois |
Multiplexed supramolecular assemblies for non-viral delivery of genetic material
|
|
CN101935365B
(en)
*
|
2010-08-25 |
2012-03-21 |
华东理工大学 |
Method for synthesizing brain targeting head modification cyclodextrin (CD) derivative
|
|
EP2627657B1
(en)
|
2010-10-13 |
2016-02-03 |
University of Maryland, College Park |
CUCURBIT[n]URIL-TYPE MOLECULAR CONTAINERS AND METHODS OF MAKING AND USING SAME
|
|
US9566351B2
(en)
|
2010-10-13 |
2017-02-14 |
University Of Maryland, College Park |
Molecular containers and methods of making and using same
|
|
CN102443200B
(en)
*
|
2011-09-22 |
2013-10-16 |
四川大学 |
Ph sensitive shape memory material and preparation method thereof
|
|
AU2012340086A1
(en)
|
2011-11-17 |
2014-05-29 |
The Regents Of The University Of California |
Therapeutic RNA switches compositions and methods of use
|
|
US9035039B2
(en)
|
2011-12-22 |
2015-05-19 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing SMAD4
|
|
EP2801617B1
(en)
|
2012-01-07 |
2017-09-06 |
Bonac Corporation |
Single-stranded nucleic acid molecule having amino acid backbone
|
|
US9827321B2
(en)
|
2012-08-14 |
2017-11-28 |
The Trustees Of The University Of Pennsylvania |
Stabilizing shear-thinning hydrogels
|
|
WO2014055493A1
(en)
|
2012-10-02 |
2014-04-10 |
Cerulean Pharma Inc. |
Methods and systems for polymer precipitation and generation of particles
|
|
US9468681B2
(en)
|
2013-03-01 |
2016-10-18 |
California Institute Of Technology |
Targeted nanoparticles
|
|
US9132097B2
(en)
|
2013-03-01 |
2015-09-15 |
California Institute Of Technology |
Nanoparticles stabilized with nitrophenylboronic acid compositions
|
|
JP6358661B2
(en)
*
|
2013-03-19 |
2018-07-18 |
公立大学法人首都大学東京 |
Surfactant-like compound
|
|
JP6180241B2
(en)
*
|
2013-08-29 |
2017-08-16 |
学校法人同志社 |
Cyclodextrin derivatives and pharmaceutical compositions
|
|
JP6468777B2
(en)
*
|
2014-09-30 |
2019-02-13 |
株式会社リバネス |
Improved folic acid modified cyclodextrin derivatives
|
|
JP2017536092A
(en)
|
2014-10-02 |
2017-12-07 |
プロティバ バイオセラピューティクス インコーポレイテッド |
Compositions and methods for silencing gene expression of hepatitis B virus
|
|
CN104840975B
(en)
*
|
2015-04-24 |
2018-01-23 |
南开大学 |
A kind of super-molecule assembling body and preparation method of targeted delivery siRNA
|
|
WO2016197132A1
(en)
|
2015-06-04 |
2016-12-08 |
Protiva Biotherapeutics Inc. |
Treating hepatitis b virus infection using crispr
|
|
JP6914860B2
(en)
|
2015-07-01 |
2021-08-04 |
カリフォルニア インスティチュート オブ テクノロジー |
Cationic mucic acid polymer delivery system
|
|
WO2017019891A2
(en)
|
2015-07-29 |
2017-02-02 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing hepatitis b virus gene expression
|
|
IL243839B
(en)
|
2016-01-28 |
2018-01-31 |
Sp Nano Ltd |
Conductive yarn
|
|
IL243838A
(en)
|
2016-01-28 |
2017-07-31 |
Sp Nano Ltd |
Composition comprising sp1 and carbon based nanoparticles and uses thereof
|
|
US20210188895A1
(en)
|
2017-10-13 |
2021-06-24 |
Bonac Corporation |
Single-stranded nucleic acid molecule, and production method therefor
|
|
WO2019241327A1
(en)
|
2018-06-13 |
2019-12-19 |
California Institute Of Technology |
Nanoparticles for crossing the blood brain barrier and methods of treatment using the same
|
|
CN109134709B
(en)
*
|
2018-07-19 |
2020-08-25 |
昆明理工大学 |
Amino modified cyclodextrin bonded ring-opening cucurbituril bonding compound and preparation method and application thereof
|
|
CN109160995B
(en)
*
|
2018-08-19 |
2021-02-23 |
南京理工大学 |
Column [5] arene self-assembly elastomer material and preparation method thereof
|
|
JP7453687B2
(en)
*
|
2018-12-05 |
2024-03-21 |
国立大学法人大阪大学 |
Polymer materials and their manufacturing methods, and polymer compositions
|
|
EP3903822A4
(en)
*
|
2018-12-27 |
2022-08-31 |
National University Corporation Kumamoto University |
Brain-penetrating ligand and drug carrier
|
|
KR102286453B1
(en)
*
|
2019-06-19 |
2021-08-09 |
한국과학기술연구원 |
Hydrogel inclusion complex comprising physiologically active materials bound to thermosensitive polyphosphazene by host-guest interaction using β-cyclodextrin and use thereof
|
|
US20240032535A1
(en)
*
|
2020-12-14 |
2024-02-01 |
Bps Just Energy Technology, Llc |
Antimicrobial compositions and methods with supramolecular structures
|
|
CN115160454A
(en)
*
|
2021-04-01 |
2022-10-11 |
四川大学 |
Supermolecule polyaldehyde compound based on poly-beta-cyclodextrin and adamantane host-guest action and preparation method thereof
|
|
CN113234183B
(en)
*
|
2021-06-24 |
2022-07-22 |
西北民族大学 |
Clathrate monomer based on subject-object recognition, preparation method thereof, starch-styrene-acrylic antibacterial emulsion, and preparation method and application thereof
|
|
CN113603823B
(en)
*
|
2021-09-10 |
2022-05-03 |
广东电网有限责任公司 |
Anti-ultraviolet repair material and preparation method and application thereof
|
|
CN114833336B
(en)
*
|
2022-04-21 |
2023-08-04 |
南开大学 |
Printable liquid metal emulsion colloid and preparation method and application thereof
|