AU2001288908A1 - Antisense modulation of mekk3 expression - Google Patents
Antisense modulation of mekk3 expressionInfo
- Publication number
- AU2001288908A1 AU2001288908A1 AU2001288908A AU8890801A AU2001288908A1 AU 2001288908 A1 AU2001288908 A1 AU 2001288908A1 AU 2001288908 A AU2001288908 A AU 2001288908A AU 8890801 A AU8890801 A AU 8890801A AU 2001288908 A1 AU2001288908 A1 AU 2001288908A1
- Authority
- AU
- Australia
- Prior art keywords
- mekk3
- expression
- antisense modulation
- antisense
- modulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/11—Protein-serine/threonine kinases (2.7.11)
- C12Y207/11025—Mitogen-activated protein kinase kinase kinase (2.7.11.25), i.e. MAPKKK or MAP3K
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/33—Chemical structure of the base
- C12N2310/334—Modified C
- C12N2310/3341—5-Methylcytosine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/341—Gapmers, i.e. of the type ===---===
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/346—Spatial arrangement of the modifications having a combination of backbone and sugar modifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/658,688 US6498035B1 (en) | 2000-09-08 | 2000-09-08 | Antisense modulation of MEKK3 expression |
US09658688 | 2000-09-08 | ||
PCT/US2001/028118 WO2002020550A1 (en) | 2000-09-08 | 2001-09-07 | Antisense modulation of mekk3 expression |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001288908A1 true AU2001288908A1 (en) | 2002-03-22 |
Family
ID=24642242
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001288908A Abandoned AU2001288908A1 (en) | 2000-09-08 | 2001-09-07 | Antisense modulation of mekk3 expression |
Country Status (3)
Country | Link |
---|---|
US (2) | US6498035B1 (en) |
AU (1) | AU2001288908A1 (en) |
WO (1) | WO2002020550A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050059028A1 (en) * | 2002-11-18 | 2005-03-17 | Genospectra, Inc. | RNAi-based sensors, caged interfering RNAs, and methods of use thereof |
WO2004065579A2 (en) * | 2003-01-16 | 2004-08-05 | Isis Pharmaceuticals, Inc. | Modified oligonucleotides for use in gene modulation |
CA2529658C (en) | 2003-06-23 | 2017-09-12 | Pioneer Hi-Bred International, Inc. | Engineering single-gene-controlled staygreen potential into plants |
WO2005056825A1 (en) * | 2003-12-05 | 2005-06-23 | Board Of Regents, The University Of Texas System | Screening for modulators of mekk2 and mekk3 |
EP2463388B1 (en) | 2005-11-29 | 2017-11-22 | Cambridge Enterprise Limited | Markers for breast cancer |
EP2272969A1 (en) | 2009-07-10 | 2011-01-12 | Schmülling, Thomas | Disruption of CKX3 and at least one other CKX gene in a plant or plant cell leads to improved traits |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5405941A (en) | 1993-04-15 | 1995-04-11 | National Jewish Center For Immunology And Respiratory Medicine | MEKK protein, capable of phosphorylating MEK |
US5981265A (en) | 1993-04-15 | 1999-11-09 | National Jewish Center For Immunology And Respiratory Medicine | Methods for regulating MEKK protein activity |
US6074861A (en) | 1993-04-15 | 2000-06-13 | National Jewish Center For Immunology And Respiratory Medicine | MEKK proteins |
US5801154A (en) * | 1993-10-18 | 1998-09-01 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide modulation of multidrug resistance-associated protein |
US5736381A (en) * | 1995-05-19 | 1998-04-07 | Davis; Roger J. | Cytokine-, stress-, and oncoprotein-activated human protein kinase kinases |
US5910417A (en) | 1996-05-31 | 1999-06-08 | National Jewish Center For Immunology And Respiratory Medicine | Regulation of cytokine production in a hematopoietic cell |
WO1998054203A1 (en) | 1997-05-28 | 1998-12-03 | Mercola Daniel A | Inhibition of stress activated protein kinase (sapk) pathway and sensitization of cells to cancer therapies |
US6312934B1 (en) | 1998-03-16 | 2001-11-06 | National Jewish Center For Immunology And Respiratory Medicine | Human MEKK proteins, corresponding nucleic acid molecules, and uses therefor |
-
2000
- 2000-09-08 US US09/658,688 patent/US6498035B1/en not_active Expired - Lifetime
-
2001
- 2001-09-07 WO PCT/US2001/028118 patent/WO2002020550A1/en active Application Filing
- 2001-09-07 AU AU2001288908A patent/AU2001288908A1/en not_active Abandoned
- 2001-09-07 US US10/380,127 patent/US20040033976A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20040033976A1 (en) | 2004-02-19 |
WO2002020550A1 (en) | 2002-03-14 |
US6498035B1 (en) | 2002-12-24 |
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