AU2001242279A1 - Ligase/polymerase method for detecting cytosine methylation in DNA samples - Google Patents

Ligase/polymerase method for detecting cytosine methylation in DNA samples

Info

Publication number: AU2001242279A1
Authority: AU; Australia
Prior art keywords: ligase; dna samples; cytosine methylation; detecting cytosine; polymerase method
Prior art date: 2000-02-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

AU2001242279A

Other versions

AU2001242279B2 (en

Inventor

Kurt Berlin

Alexander Olek

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Epigenomics AG

Original Assignee

Epigenomics AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-02-25

Filing date

2001-02-23

Publication date

2001-11-15

2000-02-25 Priority claimed from DE10010281A external-priority patent/DE10010281B4/en

2001-02-23 Application filed by Epigenomics AG filed Critical Epigenomics AG

2001-11-15 Publication of AU2001242279A1 publication Critical patent/AU2001242279A1/en

2006-10-26 Application granted granted Critical

2006-10-26 Publication of AU2001242279B2 publication Critical patent/AU2001242279B2/en

2021-02-23 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE10010281.6		2000-02-25
DE10010281A DE10010281B4 (en)	2000-02-25	2000-02-25	Ligase / polymerase method for the detection of cytosine methylation in DNA samples
PCT/DE2001/000749 WO2001062961A1 (en)	2000-02-25	2001-02-23	Ligase/polymerase method for detecting cytosine methylation in dna samples

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2006236059A Division AU2006236059A1 (en)	2000-02-25	2006-11-17	Ligase/polymerase method for detecting cytosine methylation in DNA samples

Publications (2)

Publication Number	Publication Date
AU2001242279A1 true AU2001242279A1 (en)	2001-11-15
AU2001242279B2 AU2001242279B2 (en)	2006-10-26

Family

ID=7633312

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AU4227901A Pending AU4227901A (en)	2000-02-25	2001-02-23	Ligase/polymerase method for detecting cytosine methylation in dna samples
AU2001242279A Ceased AU2001242279B2 (en)	2000-02-25	2001-02-23	Ligase/polymerase method for detecting cytosine methylation in DNA samples
AU2006236059A Abandoned AU2006236059A1 (en)	2000-02-25	2006-11-17	Ligase/polymerase method for detecting cytosine methylation in DNA samples

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AU4227901A Pending AU4227901A (en)	2000-02-25	2001-02-23	Ligase/polymerase method for detecting cytosine methylation in dna samples

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AU2006236059A Abandoned AU2006236059A1 (en)	2000-02-25	2006-11-17	Ligase/polymerase method for detecting cytosine methylation in DNA samples

Country Status (7)

Country	Link
US (1)	US7405040B2 (en)
EP (1)	EP1261740A1 (en)
JP (1)	JP2003523752A (en)
AU (3)	AU4227901A (en)
CA (1)	CA2401198A1 (en)
DE (1)	DE10010281B4 (en)
WO (1)	WO2001062961A1 (en)

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US8076063B2 (en)	2000-02-07	2011-12-13	Illumina, Inc.	Multiplexed methylation detection methods
DE10010280B4 (en) *	2000-02-25	2006-08-10	Epigenomics Ag	Method for the detection of cytosine methylation in DNA samples
DE10154318A1 (en) *	2001-10-26	2003-05-15	Epigenomics Ag	Method for analyzing genomic methylation patterns
US20110151438A9 (en)	2001-11-19	2011-06-23	Affymetrix, Inc.	Methods of Analysis of Methylation
EP1860200A1 (en) *	2001-12-03	2007-11-28	Illumina, Inc.	Multiplexed methylation detection methods
DE10201138B4 (en) *	2002-01-08	2005-03-10	Epigenomics Ag	Method for the detection of cytosine methylation patterns by exponential ligation of hybridized probe oligonucleotides (MLA)
US20040101843A1 (en) *	2002-11-22	2004-05-27	Gerald Zon	Detection of methylated DNA sites
US20060094016A1 (en) *	2002-12-02	2006-05-04	Niall Gormley	Determination of methylation of nucleic acid sequences
AU2003900368A0 (en) *	2003-01-24	2003-02-13	Human Genetic Signatures Pty Ltd	Assay for nucleic acid molecules
US7288373B2 (en) *	2003-05-02	2007-10-30	Human Genetic Signatures Pty Ltd.	Treatment of methylated nucleic acid
US20050009059A1 (en) *	2003-05-07	2005-01-13	Affymetrix, Inc.	Analysis of methylation status using oligonucleotide arrays
WO2004111266A1 (en) *	2003-06-17	2004-12-23	Human Genetic Signatures Pty Ltd	Methods for genome amplification
US7846693B2 (en) *	2003-09-04	2010-12-07	Human Genetic Signatures Pty. Ltd.	Nucleic acid detection assay
US8168777B2 (en)	2004-04-29	2012-05-01	Human Genetic Signatures Pty. Ltd.	Bisulphite reagent treatment of nucleic acid
US7364855B2 (en) *	2004-04-30	2008-04-29	Applera Corporation	Methods and kits for methylation detection
US20060234252A1 (en) *	2004-07-02	2006-10-19	Applera Corporation	Methods and kits for methylation detection
DE602005022740D1 (en) *	2004-09-10	2010-09-16	Human Genetic Signatures Pty	AMPLIFICATION BLOCKERS COMPRISING INTERCALING NUCLEIC ACIDS (INA) CONTAINING INTERCALING PSEUDONUCLEOTIDES (IPN)
WO2006058393A1 (en) *	2004-12-03	2006-06-08	Human Genetic Signatures Pty Ltd	Methods for simplifying microbial nucleic acids by chemical modification of cytosines
US20060134650A1 (en) *	2004-12-21	2006-06-22	Illumina, Inc.	Methylation-sensitive restriction enzyme endonuclease method of whole genome methylation analysis
AU2005318874B2 (en) *	2004-12-23	2007-05-03	Human Genetic Signatures Pty Ltd	Detection of human papilloma virus
AU2006236363B2 (en)	2005-04-15	2012-11-01	Epigenomics Ag	A method for providing DNA fragments derived from a remote sample
CN101203618B (en) *	2005-05-26	2013-03-13	人类遗传标记控股有限公司	Isothermal strand displacement amplification using primers containing a non-regular base
US20060292585A1 (en) *	2005-06-24	2006-12-28	Affymetrix, Inc.	Analysis of methylation using nucleic acid arrays
AU2006292033B2 (en) *	2005-09-14	2010-08-12	Human Genetic Signatures Pty Ltd	Assay for a health state
EP1969139A1 (en)	2005-11-17	2008-09-17	Epigenomics AG	Method for the determination of the dna methylation level of a cpg position in identical cells within a tissue sample
US7820385B2 (en) *	2006-03-22	2010-10-26	The United States Of America As Represented By The Department Of Health And Human Services, Centers For Disease Control And Prevention	Method for retaining methylation pattern in globally amplified DNA
US7901882B2 (en)	2006-03-31	2011-03-08	Affymetrix, Inc.	Analysis of methylation using nucleic acid arrays
US8084734B2 (en) *	2006-05-26	2011-12-27	The George Washington University	Laser desorption ionization and peptide sequencing on laser induced silicon microcolumn arrays
US20080050738A1 (en) *	2006-05-31	2008-02-28	Human Genetic Signatures Pty Ltd.	Detection of target nucleic acid
WO2008096146A1 (en)	2007-02-07	2008-08-14	Solexa Limited	Preparation of templates for methylation analysis
CA2680426A1 (en) *	2007-03-16	2008-09-25	Human Genetic Signatures Pty Ltd	Assay for gene expression
DK2479289T3 (en)	2007-06-08	2016-05-02	Epigenomics Ag	Method for methylation analysis
EP2215250B1 (en) *	2007-11-27	2013-02-27	Human Genetic Signatures Pty Ltd	Enzymes for amplification and copying bisulphite modified nucleic acids
US20110003700A1 (en) *	2007-12-20	2011-01-06	Human Genetic Signatures Pty Ltd.	Elimination of contaminants associated with nucleic acid amplification
WO2010048337A2 (en)	2008-10-22	2010-04-29	Illumina, Inc.	Preservation of information related to genomic dna methylation
US8110796B2 (en)	2009-01-17	2012-02-07	The George Washington University	Nanophotonic production, modulation and switching of ions by silicon microcolumn arrays
US9490113B2 (en) *	2009-04-07	2016-11-08	The George Washington University	Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry
ES2534200T3 (en)	2009-08-03	2015-04-20	Epigenomics Ag	Methods for preserving the complexity of the genomic DNA sequence
US20110104695A1 (en)	2009-11-05	2011-05-05	Epigenomics Ag	Methods of predicting therapeutic efficacy of cancer therapy
NZ622418A (en)	2011-09-07	2014-12-24	Human Genetic Signatures Pty	Molecular detection assay
CA3169966A1 (en)	2020-03-03	2021-09-10	John E. Gill	Methods for assembling nucleic acids

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US4988617A (en) *	1988-03-25	1991-01-29	California Institute Of Technology	Method of detecting a nucleotide change in nucleic acids
US6013431A (en) *	1990-02-16	2000-01-11	Molecular Tool, Inc.	Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
DE69531542T2 (en) *	1994-02-07	2004-06-24	Beckman Coulter, Inc., Fullerton	LIGASE / POLYMERASE-MEDIATED ANALYSIS OF GENETIC ELEMENTS OF SINGLE-NUCLEOTIDE POLYMORPHISMS AND THEIR USE IN GENETIC ANALYSIS
US5728526A (en) *	1995-06-07	1998-03-17	Oncor, Inc.	Method for analyzing a nucleotide sequence
EP1736554B1 (en) *	1996-05-29	2013-10-09	Cornell Research Foundation, Inc.	Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
DE19754482A1 (en) *	1997-11-27	1999-07-01	Epigenomics Gmbh	Process for making complex DNA methylation fingerprints
WO1999067414A1 (en) *	1998-06-24	1999-12-29	Glaxo Group Limited	Nucleotide detection method
DE10010280B4 (en) *	2000-02-25	2006-08-10	Epigenomics Ag	Method for the detection of cytosine methylation in DNA samples
DE10029915B4 (en) *	2000-06-19	2005-06-16	Epigenomics Ag	Method for the detection of cytosine methylations

2000
- 2000-02-25 DE DE10010281A patent/DE10010281B4/en not_active Expired - Fee Related
2001
- 2001-02-23 JP JP2001561769A patent/JP2003523752A/en active Pending
- 2001-02-23 EP EP01915053A patent/EP1261740A1/en not_active Withdrawn
- 2001-02-23 AU AU4227901A patent/AU4227901A/en active Pending
- 2001-02-23 US US10/204,961 patent/US7405040B2/en not_active Expired - Fee Related
- 2001-02-23 CA CA002401198A patent/CA2401198A1/en not_active Abandoned
- 2001-02-23 AU AU2001242279A patent/AU2001242279B2/en not_active Ceased
- 2001-02-23 WO PCT/DE2001/000749 patent/WO2001062961A1/en active Application Filing
2006
- 2006-11-17 AU AU2006236059A patent/AU2006236059A1/en not_active Abandoned

Publication	Publication Date	Title
AU2001242279A1 (en)	2001-11-15	Ligase/polymerase method for detecting cytosine methylation in DNA samples
AU4227901A (en)	2001-09-03	Ligase/polymerase method for detecting cytosine methylation in dna samples
AU2001242280A1 (en)	2001-11-15	Method for detecting cytosine methylation in dna samples
AU2002212188A1 (en)	2002-06-06	Method for determining the degree of methylation of defined cytosines in genomic DNA in the sequence context 5'-CPG-3'
AU2001242277A1 (en)	2001-11-15	Method for detecting cytosine methylation in DNA samples
AU2002311897A1 (en)	2002-11-18	Nucleic acid detection in pooled samples
AU2001273840A1 (en)	2001-10-23	Detection of variations in the DNA methylation profile
AU2001264811A1 (en)	2001-12-03	Methods for genetic analysis of dna to detect sequence variances
AU2002227866A1 (en)	2002-06-18	Method for quantifying cytosine methylations in genomic dna that is amplified in a complex manner
AU2002363259A1 (en)	2003-07-10	Method for the detection of cytosine methylation in immobilised DNA samples
IL138229A0 (en)	2001-10-31	Method and system for detecting nucleic acids
AU2001241733A1 (en)	2001-09-03	Methods for determining single nucleotide variations
AU4975300A (en)	2000-11-17	Dna melting curve analysis
AU2003903430A0 (en)	2003-07-17	Method for detection of alkylated cytosine in dna
AU5885100A (en)	2001-01-30	Method for determining dna double-stranded breaks
IL143176A0 (en)	2002-04-21	Method for identifying cytosine methylation patterns in genomic dna
AU3922802A (en)	2002-05-27	Methods for identifying nucleotides at defined positions in target nucleic acidsusing fluorescence polarization
AU4099001A (en)	2001-09-24	Nucleic acid detection method and system
AU2003230619A1 (en)	2003-09-22	Compositions and methods for detecting nucleic acid methylation
AU2001270635A1 (en)	2002-02-18	Method for detecting mutations in nucleotide sequences
AU2001254601A1 (en)	2001-09-24	Oligonucleotides or pna oligomers and a method for detecting the methylation state of genomic dna in a parallel manner
AU2003302685A1 (en)	2004-06-23	Methylation dna detecting method
AU2001292922A1 (en)	2002-04-29	Nucleic acid detection
AU2001266212A1 (en)	2002-01-08	Method for dna extraction
AU8346901A (en)	2002-03-04	Method for transdermal nucleic acid sampling