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AU2000258410A1 - New method for the preparation of the anti-ulcer compounds omeprazole, lansoprazole and pantoprazole - Google Patents

New method for the preparation of the anti-ulcer compounds omeprazole, lansoprazole and pantoprazole

Info

Publication number
AU2000258410A1
AU2000258410A1 AU2000258410A AU2000258410A AU2000258410A1 AU 2000258410 A1 AU2000258410 A1 AU 2000258410A1 AU 2000258410 A AU2000258410 A AU 2000258410A AU 2000258410 A AU2000258410 A AU 2000258410A AU 2000258410 A1 AU2000258410 A1 AU 2000258410A1
Authority
AU
Australia
Prior art keywords
pantoprazole
lansoprazole
preparation
new method
ulcer compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2000258410A
Other versions
AU2000258410A8 (en
Inventor
Jose Enrique Borges
Luis Brito Correia
Pedro Brito Correia
Maria Do Ceu Costa
Ana Cristina Fernandes
Maria Florbela Pereira
Carlos Crispim Romao
Regina Tavares
Fatima Teixeira
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HERBEX PRODUTOS QUIMICOS SA
Saragga Jose Manuel
Original Assignee
HERBEX PRODUTOS QUIMICOS SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HERBEX PRODUTOS QUIMICOS SA filed Critical HERBEX PRODUTOS QUIMICOS SA
Publication of AU2000258410A1 publication Critical patent/AU2000258410A1/en
Publication of AU2000258410A8 publication Critical patent/AU2000258410A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2000258410A 2000-07-28 2000-07-28 New method for the preparation of the anti-ulcer compounds omeprazole, lansoprazole and pantoprazole Abandoned AU2000258410A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2000/001057 WO2003097606A1 (en) 2000-07-28 2000-07-28 New method for the preparation of the anti-ulcer compounds omeprazole, lansoprazole and pantoprazole

Publications (2)

Publication Number Publication Date
AU2000258410A1 true AU2000258410A1 (en) 2003-12-02
AU2000258410A8 AU2000258410A8 (en) 2003-12-02

Family

ID=29434046

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2000258410A Abandoned AU2000258410A1 (en) 2000-07-28 2000-07-28 New method for the preparation of the anti-ulcer compounds omeprazole, lansoprazole and pantoprazole

Country Status (2)

Country Link
AU (1) AU2000258410A1 (en)
WO (1) WO2003097606A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE327233T1 (en) * 2002-12-23 2006-06-15 Chemi Spa METHOD FOR PRODUCING SULFINYL DERIVATIVES BY OXIDATION OF THE CORRESPONDING SULFIDES
FR2863611B1 (en) * 2003-12-15 2006-03-24 Sidem Pharma Sa PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF SULFOXIDE DERIVATIVES
US7683177B2 (en) 2003-06-10 2010-03-23 Teva Pharmaceutical Industries Ltd Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
WO2005054228A1 (en) * 2003-12-05 2005-06-16 Hetero Drugs Limited A process for the preparation of substitited pyridinylmethylsulfinyl- benzimidazole enantiomers
SE0400410D0 (en) * 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
ES2264362B1 (en) * 2004-12-22 2007-11-01 Laboratorios Viñas S.A. "PROCEDURE FOR OBTAINING DERIVATIVES OF 2- (2-PIRIDINILMETILSUFINIL-1H-BENZIMIDAZOLES").
ES2273564B1 (en) * 2005-03-22 2008-04-01 Quimica Sintetica, S.A. PROCEDURE FOR THE PREPARATION OF PANTOPRAZOLE.
JP2010077030A (en) * 2008-09-24 2010-04-08 Ihara Nikkei Kagaku Kogyo Kk Manufacturing method of 2-chloromethyl-6-methylpyridine
CN102942523A (en) * 2012-12-05 2013-02-27 寿光富康制药有限公司 Preparation method of omeprazole intermediate 2,3,5-trimethylpyridyl-N-oxide
CN103664886A (en) * 2013-12-06 2014-03-26 威海迪素制药有限公司 Preparation method of 2-[[[4-(3-methoxypropoxy)-3-methylpyridine-2-yl]-methyl]thio]-1H-benzimidazole
EP3187494A1 (en) 2015-12-30 2017-07-05 KRKA, tovarna zdravil, d.d., Novo mesto Process for the preparation of pantoprazole sodium sesquihydrate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8204879D0 (en) * 1982-08-26 1982-08-26 Haessle Ab NOVEL CHEMICAL INTERMEDIATES
ES2026761A6 (en) * 1990-10-31 1992-05-01 Genesis Para La Investigacion A process for the preparation of omeprazol.
US5670526A (en) * 1995-12-21 1997-09-23 Otsuka Pharmaceutical Co., Ltd. 1,3,4-oxadiazoles

Also Published As

Publication number Publication date
WO2003097606A1 (en) 2003-11-27
AU2000258410A8 (en) 2003-12-02

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase
TH Corrigenda

Free format text: IN VOL 18, NO 25, PAGE(S) 6948 UNDER THE HEADING APPLICATIONS OPI - NAME INDEX UNDER THE NAME HERBEX, PRODUTOS QUIMICOS, SA, APPLICATION NO. 2000258410, UNDER INID (71) CORRECT THE NAME TO READ HERBEX, PRODUTOS QUIMICOS, SA; SARAGGA, JOS#, MANUEL