AU1018092A - Dideoxydidehydrocarbocyclic pyrimidines - Google Patents

Dideoxydidehydrocarbocyclic pyrimidines

Info

Publication number: AU1018092A
Authority: AU; Australia
Prior art keywords: dideoxydidehydrocarbocyclic; pyrimidines; dideoxydidehydrocarbocyclic pyrimidines
Prior art date: 1988-01-20
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

AU10180/92A

Other versions

AU637015B2 (en

Inventor

Mei Hua

Peter Leslie Myers

Richard Storer

Robert Vince

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of Minnesota

Original Assignee

University of Minnesota

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-20

Filing date

1992-01-13

Publication date

1992-03-12

1988-01-20 Priority claimed from US07/146,252 external-priority patent/US4916224A/en

1988-09-07 Priority claimed from GB888821011A external-priority patent/GB8821011D0/en

1988-12-05 Priority claimed from US07/278,652 external-priority patent/US4931559A/en

1992-01-13 Application filed by University of Minnesota filed Critical University of Minnesota

1992-03-12 Publication of AU1018092A publication Critical patent/AU1018092A/en

1993-05-13 Application granted granted Critical

1993-05-13 Publication of AU637015B2 publication Critical patent/AU637015B2/en

2009-01-20 Anticipated expiration legal-status Critical

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Virology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

AU10180/92A 1988-01-20 1992-01-13 Dideoxydidehydrocarbocyclic pyrimidines Expired AU637015B2 (en)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US07/146,252 US4916224A (en)	1988-01-20	1988-01-20	Dideoxycarbocyclic nucleosides
US146252		1988-01-20
GB8821011		1988-09-07
GB888821011A GB8821011D0 (en)	1988-09-07	1988-09-07	Chemical compounds
US278652		1988-12-05
US07/278,652 US4931559A (en)	1988-01-20	1988-12-05	Optically-active isomers of dideoxycarbocyclic nucleosides

Related Parent Applications (1)

Application Number	Title	Priority Date	Filing Date
AU28671/89A Division AU626278B2 (en)	1988-01-20	1989-01-20	Dideoxydidehydrocarbocyclic nucleosides

Publications (2)

Publication Number	Publication Date
AU1018092A true AU1018092A (en)	1992-03-12
AU637015B2 AU637015B2 (en)	1993-05-13

Family

ID=27264063

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AU28671/89A Expired AU626278B2 (en)	1988-01-20	1989-01-20	Dideoxydidehydrocarbocyclic nucleosides
AU10180/92A Expired AU637015B2 (en)	1988-01-20	1992-01-13	Dideoxydidehydrocarbocyclic pyrimidines

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AU28671/89A Expired AU626278B2 (en)	1988-01-20	1989-01-20	Dideoxydidehydrocarbocyclic nucleosides

Country Status (29)

Country	Link
JP (1)	JP2793825B2 (en)
KR (1)	KR0127137B1 (en)
AT (1)	AT397801B (en)
AU (2)	AU626278B2 (en)
BE (1)	BE1003815A4 (en)
CA (1)	CA1339896C (en)
CH (1)	CH679152A5 (en)
DE (1)	DE3901502C2 (en)
DK (1)	DK175131B1 (en)
ES (1)	ES2010091A6 (en)
FI (1)	FI93546C (en)
FR (1)	FR2626002B1 (en)
GB (1)	GB2217320B (en)
GR (1)	GR890100033A (en)
HU (1)	HU203755B (en)
IE (1)	IE62275B1 (en)
IL (1)	IL88999A (en)
IT (1)	IT1229531B (en)
LU (1)	LU87437A1 (en)
MY (1)	MY103801A (en)
NL (1)	NL8900122A (en)
NO (1)	NO169123C (en)
NZ (1)	NZ227663A (en)
OA (1)	OA09031A (en)
PL (1)	PL163814B1 (en)
PT (1)	PT89482B (en)
RU (1)	RU2114846C1 (en)
SE (1)	SE505213C2 (en)
YU (1)	YU47791B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1215339B (en) *	1987-01-14	1990-02-08	Co Pharma Corp Srl	PROCEDURE FOR THE PREPARATION OF 9- (HYDROXIALCHIL) -IPOXANTINE
US5631370A (en)	1988-01-20	1997-05-20	Regents Of The University Of Minnesota	Optically-active isomers of dideoxycarbocyclic nucleosides
GB8815265D0 (en) *	1988-06-27	1988-08-03	Wellcome Found	Therapeutic nucleosides
US4939252A (en) *	1989-04-20	1990-07-03	Hoffmann-La Roche Inc.	Novel intermediates for the preparation of Carbovir
ES2136061T3 (en) *	1989-06-27	1999-11-16	Wellcome Found	THERAPEUTIC NUCLEOSIDES.
GB8916477D0 (en) *	1989-07-19	1989-09-06	Glaxo Group Ltd	Chemical process
GB8916480D0 (en) *	1989-07-19	1989-09-06	Glaxo Group Ltd	Chemical process
GB8916479D0 (en) *	1989-07-19	1989-09-06	Glaxo Group Ltd	Chemical process
GB8916478D0 (en) *	1989-07-19	1989-09-06	Glaxo Group Ltd	Chemical process
MY104575A (en) *	1989-12-22	1994-04-30	The Wellcome Foundation Ltd	Therapeutic nucleosides.
US5241069A (en) *	1990-04-06	1993-08-31	Glaxo Inc.	Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives
US5144034A (en) *	1990-04-06	1992-09-01	Glaxo Inc.	Process for the synthesis of cyclopentene derivatives of purines
US5126452A (en) *	1990-04-06	1992-06-30	Glaxo Inc.	Synthesis of purine substituted cyclopentene derivatives
US5057630A (en) *	1990-04-06	1991-10-15	Glaxo Inc.	Synthesis of cyclopentene derivatives
GB9108376D0 (en) *	1991-04-19	1991-06-05	Enzymatix Ltd	Cyclopentenes
JPH09509397A (en) *	1993-11-12	1997-09-22	メレルファーマス−ティカルズインコーポレイテッド	6-oxo-nucleosides useful as immunosuppressants
GB9721780D0 (en)	1997-10-14	1997-12-10	Glaxo Group Ltd	Process for the synthesis of chloropurine intermediates
DE59905679D1 (en)	1998-10-30	2003-06-26	Lonza Ag	METHOD FOR PRODUCING 4 - [(2 ', 5'-DIAMINO-6'-HALOGENPYRIMIDIN-4'-YL) AMINO] -CYCLOPENT-2-ENYLMETHANOLS
SK285271B6 (en) *	1998-10-30	2006-10-05	Lonza Ag	Method for producing 4-[(2',5'-diamino-6'-halopyrimidine-4'- yl)amino]-cyclopent-2-enylmethanols
TWI229674B (en)	1998-12-04	2005-03-21	Astra Pharma Prod	Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
GB9903091D0 (en) *	1999-02-12	1999-03-31	Glaxo Group Ltd	Therapeutic nucleoside compound
AR039540A1 (en)	2002-05-13	2005-02-23	Tibotec Pharm Ltd	MICROBICIDE COMPOUNDS WITH PIRIMIDINE OR TRIAZINE CONTENT
JP7104154B2 (en)	2018-07-27	2022-07-20	富士フイルム株式会社	Cyclopentenylpurine derivative or salt thereof
EP4125840A1 (en)	2020-03-27	2023-02-08	Som Innovation Biotech, S.A.	Compounds for use in the treatment of synucleinopathies

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4268672A (en) *	1977-02-09	1981-05-19	The Regents Of The University Of Minnesota	Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
US4742064A (en) *	1985-09-10	1988-05-03	Regents Of The University Of Minnesota	Antiviral carbocyclic analogs of xylofuranosylpurines
JPS62177234A (en) *	1986-01-30	1987-08-04	Mitsubishi Heavy Ind Ltd	Production device of carbon fiber by centrifugal spinning
IN164556B (en) *	1986-03-06	1989-04-08	Takeda Chemical Industries Ltd
NZ229453A (en) *	1988-06-10	1991-08-27	Univ Minnesota & Southern Rese	A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) *	1988-06-27	1988-08-03	Wellcome Found	Therapeutic nucleosides
MY104575A (en) *	1989-12-22	1994-04-30	The Wellcome Foundation Ltd	Therapeutic nucleosides.

1989
- 1989-01-19 HU HU89210A patent/HU203755B/en unknown
- 1989-01-19 CH CH172/89A patent/CH679152A5/de not_active IP Right Cessation
- 1989-01-19 PL PL89277261A patent/PL163814B1/en unknown
- 1989-01-19 FR FR8900592A patent/FR2626002B1/en not_active Expired - Lifetime
- 1989-01-19 GB GB8901187A patent/GB2217320B/en not_active Expired - Lifetime
- 1989-01-19 IL IL8899989A patent/IL88999A/en unknown
- 1989-01-19 MY MYPI89000064A patent/MY103801A/en unknown
- 1989-01-19 DK DK198900234A patent/DK175131B1/en not_active IP Right Cessation
- 1989-01-19 DE DE3901502A patent/DE3901502C2/en not_active Expired - Lifetime
- 1989-01-19 GR GR890100033A patent/GR890100033A/en not_active IP Right Cessation
- 1989-01-19 SE SE8900192A patent/SE505213C2/en not_active IP Right Cessation
- 1989-01-19 YU YU12389A patent/YU47791B/en unknown
- 1989-01-19 AT AT0010689A patent/AT397801B/en not_active IP Right Cessation
- 1989-01-19 NZ NZ227663A patent/NZ227663A/en unknown
- 1989-01-19 CA CA000588614A patent/CA1339896C/en not_active Expired - Lifetime
- 1989-01-19 JP JP1008744A patent/JP2793825B2/en not_active Expired - Lifetime
- 1989-01-19 RU RU92004364A patent/RU2114846C1/en active
- 1989-01-19 OA OA59510A patent/OA09031A/en unknown
- 1989-01-19 FI FI890286A patent/FI93546C/en not_active IP Right Cessation
- 1989-01-19 IE IE15389A patent/IE62275B1/en not_active IP Right Cessation
- 1989-01-19 PT PT89482A patent/PT89482B/en not_active IP Right Cessation
- 1989-01-19 BE BE8900061A patent/BE1003815A4/en active
- 1989-01-19 NO NO890253A patent/NO169123C/en not_active IP Right Cessation
- 1989-01-19 LU LU87437A patent/LU87437A1/en unknown
- 1989-01-19 ES ES8900184A patent/ES2010091A6/en not_active Expired
- 1989-01-19 KR KR1019890000551A patent/KR0127137B1/en not_active IP Right Cessation
- 1989-01-19 NL NL8900122A patent/NL8900122A/en not_active Application Discontinuation
- 1989-01-19 IT IT8947546A patent/IT1229531B/en active
- 1989-01-20 AU AU28671/89A patent/AU626278B2/en not_active Expired
1992
- 1992-01-13 AU AU10180/92A patent/AU637015B2/en not_active Expired

Also Published As

Publication number	Publication date
CA1339896C (en)	1998-06-02
HU203755B (en)	1991-09-30
ES2010091A6 (en)	1989-10-16
OA09031A (en)	1991-03-31
IT8947546A0 (en)	1989-01-19
ATA10689A (en)	1993-11-15
DE3901502C2 (en)	2002-06-13
GB2217320B (en)	1992-04-08
BE1003815A4 (en)	1992-06-23
JPH02196788A (en)	1990-08-03
FI93546C (en)	1995-04-25
AT397801B (en)	1994-07-25
KR890011902A (en)	1989-08-23
GR890100033A (en)	1994-03-31
GB2217320A (en)	1989-10-25
HUT48887A (en)	1989-07-28
IL88999A (en)	1994-12-29
AU2867189A (en)	1989-07-20
CH679152A5 (en)	1991-12-31
DK23489A (en)	1989-07-21
SE8900192L (en)	1989-07-21
YU12389A (en)	1991-10-31
IE62275B1 (en)	1995-01-25
YU47791B (en)	1996-01-09
MY103801A (en)	1993-09-30
SE505213C2 (en)	1997-07-14
JP2793825B2 (en)	1998-09-03
NO169123C (en)	1992-05-13
NZ227663A (en)	1990-09-26
FR2626002B1 (en)	1994-01-28
KR0127137B1 (en)	1997-12-29
NO169123B (en)	1992-02-03
IE890153L (en)	1989-07-20
FR2626002A1 (en)	1989-07-21
NL8900122A (en)	1989-08-16
RU2114846C1 (en)	1998-07-10
SE8900192D0 (en)	1989-01-19
PL277261A1 (en)	1989-09-18
FI93546B (en)	1995-01-13
NO890253D0 (en)	1989-01-19
DK23489D0 (en)	1989-01-19
IT1229531B (en)	1991-09-04
PL163814B1 (en)	1994-05-31
DK175131B1 (en)	2004-06-14
GB8901187D0 (en)	1989-03-15
FI890286A (en)	1989-07-21
AU626278B2 (en)	1992-07-30
PT89482A (en)	1989-10-04
NO890253L (en)	1989-07-21
AU637015B2 (en)	1993-05-13
IL88999A0 (en)	1989-08-15
PT89482B (en)	1994-02-28
DE3901502A1 (en)	1989-07-27
FI890286A0 (en)	1989-01-19
LU87437A1 (en)	1989-08-30

Publication	Publication Date	Title
AU3715993A (en)	1993-07-01	N-isopropylheteroaryloxyacetanilides
AU638496B2 (en)	1993-07-01	Acyl-biphenylyl-alkyl pyrimidine derivatives
AU1018092A (en)	1992-03-12	Dideoxydidehydrocarbocyclic pyrimidines
AU7219487A (en)	1987-11-05	Substituted pyrimidines
AU632763B2 (en)	1993-01-14	Substituted 9h-purines
AU2864489A (en)	1989-07-20	16-dehydro-vitamin d3-derivatives
AU3642589A (en)	1989-12-21	1-aryl-2-naphthoylamines
AU3091089A (en)	1989-09-07	Substituted sulphonylaminoazoles
AU3163389A (en)	1989-09-28	5-amino-1-phenylpyrazoles
AU4169089A (en)	1990-03-29	(Diarylmethoxy)-1-pyrrolidines and-piperidines
AU3020289A (en)	1989-08-31	Substituted pyrimidines
AU3234289A (en)	1989-10-05	Co-dispenser
AU3334389A (en)	1989-11-09	Rutheniumcomplex-compounds
AU4628489A (en)	1990-05-28	Assayomate
AU4471189A (en)	1990-05-24	Substituted oxadiaminobutanes
AU3300089A (en)	1989-10-19	Triazoloazines
AU3607189A (en)	1989-12-21	Pyrimidine derivatives
AU3869789A (en)	1990-02-19	Pyrazolo-pyrrolo-pyrimidine-diones
AU3315089A (en)	1989-10-26	2-substituted-2-cyclopentenones
AU3491189A (en)	1989-12-07	Substituted dibenzothiaphenes
AU3508989A (en)	1989-11-23	Des-17-histidine-calcitonin
AU4679689A (en)	1990-06-21	Polyhydroxybenzylpxypropanolamines
AU3851189A (en)	1990-02-05	Recombinomas
AU2508688A (en)	1990-05-17	Yacht-hull
AU4184089A (en)	1990-03-23	Sieveplate