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ATE82294T1 - Therapeutische nukleoside. - Google Patents

Therapeutische nukleoside.

Info

Publication number
ATE82294T1
ATE82294T1 AT88302922T AT88302922T ATE82294T1 AT E82294 T1 ATE82294 T1 AT E82294T1 AT 88302922 T AT88302922 T AT 88302922T AT 88302922 T AT88302922 T AT 88302922T AT E82294 T1 ATE82294 T1 AT E82294T1
Authority
AT
Austria
Prior art keywords
therapeutic nucleosides
nucleosides
therapeutic
prophylaxis
processes
Prior art date
Application number
AT88302922T
Other languages
English (en)
Inventor
Joel Van Tuttle
Thomas Anthony Krenitsky
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of ATE82294T1 publication Critical patent/ATE82294T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT88302922T 1987-04-03 1988-03-31 Therapeutische nukleoside. ATE82294T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878708050A GB8708050D0 (en) 1987-04-03 1987-04-03 Therapeutic nucleosides
EP88302922A EP0285432B1 (de) 1987-04-03 1988-03-31 Therapeutische Nukleoside

Publications (1)

Publication Number Publication Date
ATE82294T1 true ATE82294T1 (de) 1992-11-15

Family

ID=10615214

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88302922T ATE82294T1 (de) 1987-04-03 1988-03-31 Therapeutische nukleoside.

Country Status (12)

Country Link
EP (1) EP0285432B1 (de)
JP (1) JPS63258891A (de)
KR (1) KR880012628A (de)
AT (1) ATE82294T1 (de)
AU (1) AU1412088A (de)
DE (1) DE3875769T2 (de)
DK (1) DK177888A (de)
GB (1) GB8708050D0 (de)
GR (1) GR3006366T3 (de)
HU (1) HU199869B (de)
IL (1) IL85945A0 (de)
ZA (1) ZA882344B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310732A (en) * 1986-02-03 1994-05-10 The Scripps Research Institute 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis
US5106837A (en) * 1988-03-16 1992-04-21 The Scripps Research Institute Adenosine derivatives with therapeutic activity
US5214048A (en) * 1987-05-19 1993-05-25 Nippon Kayaku Kabushiki Kaisha Oxetanocins
IL86381A0 (en) * 1987-05-19 1988-11-15 Nippon Kayaku Kk Oxetanocins and pharmaceutical compositions containing the same
KR0138996B1 (ko) * 1988-03-16 1998-04-30 레이몬드 에이치. 칸 치환된 아데닌 유도체 및 이를 함유하는 약제학적 조성물
US4996308A (en) * 1988-03-25 1991-02-26 Merrell Dow Pharmaceuticals Inc. Derivatives with unsaturated substitutions for the 5'-hydroxymethyl group
FI95384C (fi) * 1989-04-06 1996-01-25 Squibb Bristol Myers Co Menetelmä 3'-deoksi-3'-substituoitujen metyylinukleosidien valmistamiseksi ja menetelmässä käytettäviä välituotteita
KR910007655A (ko) * 1989-10-03 1991-05-30 엠. 피. 잭슨 치료용 뉴클레오시드
US5420115A (en) * 1990-09-10 1995-05-30 Burroughs Wellcome Co. Method for the treatment of protoza infections with 21 -deoxy-21 -fluoropurine nucleosides
WO1992011276A1 (en) * 1990-12-18 1992-07-09 Sloan-Kettering Institute For Cancer Research Novel synthesis of 2'-'up' fluorinated 2''-deoxy-arabinofuranosylpurines
JPH06321784A (ja) * 1993-03-18 1994-11-22 Nippon Chemiphar Co Ltd 抗ヒト免疫不全ウイルス剤
CA2119315A1 (en) * 1993-03-18 1994-09-19 Tsujiaki Hata Nucleoside derivatives and anti-herpes composition
US5654286A (en) * 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
KR20060095772A (ko) 2003-10-24 2006-09-01 야마사 쇼유 가부시키가이샤 α-1-인산화-2-데옥시-2-플루오로아라비노시드 및2’-데옥시-2’-플루오로-β-D-아라비노뉴클레오시드의제조법
JP6983814B2 (ja) * 2016-12-14 2021-12-17 ヤマサ醤油株式会社 抗ウイルス活性を示すヌクレオシド誘導体
WO2018181102A1 (ja) * 2017-03-29 2018-10-04 ヤマサ醤油株式会社 ヌクレオシド誘導体又はその塩、及びそれを含む医薬組成物
JP7378760B2 (ja) * 2019-03-14 2023-11-14 国立大学法人 鹿児島大学 抗b型肝炎ウイルス剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3658787A (en) * 1969-08-04 1972-04-25 Syntex Corp Halogenated purine nucleosides and derivatives
US4751221A (en) * 1985-10-18 1988-06-14 Sloan-Kettering Institute For Cancer Research 2-fluoro-arabinofuranosyl purine nucleosides

Also Published As

Publication number Publication date
JPS63258891A (ja) 1988-10-26
DE3875769D1 (de) 1992-12-17
EP0285432B1 (de) 1992-11-11
EP0285432A3 (en) 1990-01-24
IL85945A0 (en) 1988-09-30
DE3875769T2 (de) 1993-04-08
HU199869B (en) 1990-03-28
KR880012628A (ko) 1988-11-28
AU1412088A (en) 1988-10-06
EP0285432A2 (de) 1988-10-05
GB8708050D0 (en) 1987-05-07
DK177888D0 (da) 1988-03-30
GR3006366T3 (de) 1993-06-21
HUT48268A (en) 1989-05-29
DK177888A (da) 1988-10-04
ZA882344B (en) 1989-12-27

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