ATE502633T1 - Cyclosporins zur behandlung und vorbeugung von augenerkrankungen - Google Patents
Cyclosporins zur behandlung und vorbeugung von augenerkrankungenInfo
- Publication number
- ATE502633T1 ATE502633T1 AT07795039T AT07795039T ATE502633T1 AT E502633 T1 ATE502633 T1 AT E502633T1 AT 07795039 T AT07795039 T AT 07795039T AT 07795039 T AT07795039 T AT 07795039T AT E502633 T1 ATE502633 T1 AT E502633T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- cyclosporins
- prevention
- eye diseases
- methods
- Prior art date
Links
- 108010036941 Cyclosporins Proteins 0.000 title 1
- 229930182912 cyclosporin Natural products 0.000 title 1
- 208000030533 eye disease Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 208000022873 Ocular disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Laser Surgery Devices (AREA)
- Prostheses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80220806P | 2006-05-19 | 2006-05-19 | |
| PCT/US2007/011919 WO2007136759A2 (en) | 2006-05-19 | 2007-05-18 | Method for the treatment and prevention of ocular disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE502633T1 true ATE502633T1 (de) | 2011-04-15 |
Family
ID=37814449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07795039T ATE502633T1 (de) | 2006-05-19 | 2007-05-18 | Cyclosporins zur behandlung und vorbeugung von augenerkrankungen |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8188052B2 (de) |
| EP (1) | EP2023918B1 (de) |
| JP (1) | JP5377293B2 (de) |
| CN (1) | CN101511357B (de) |
| AT (1) | ATE502633T1 (de) |
| AU (1) | AU2007254148B2 (de) |
| CA (1) | CA2652662C (de) |
| DE (1) | DE602007013391D1 (de) |
| DK (1) | DK2023918T3 (de) |
| ES (1) | ES2361635T3 (de) |
| WO (1) | WO2007136759A2 (de) |
| ZA (1) | ZA200810113B (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1802650T1 (sl) * | 2004-10-01 | 2012-03-30 | Scynexis Inc | Eter in tioeter substituirani ciklosporinski derivati za zdravljenje in preventivo pred infekcijami s hepatitisom c |
| US7196161B2 (en) | 2004-10-01 | 2007-03-27 | Scynexis Inc. | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection |
| US7202209B2 (en) * | 2005-07-13 | 2007-04-10 | Allergan, Inc. | Cyclosporin compositions |
| BRPI0616476A2 (pt) | 2005-09-30 | 2011-06-21 | Scynexis Inc | uso de uma quantidade terapeuticamente eficaz de um derivado de ciclosporina, e, composição farmacêutica |
| WO2007041631A1 (en) | 2005-09-30 | 2007-04-12 | Scynexis, Inc. | ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION |
| CA2652662C (en) | 2006-05-19 | 2015-11-03 | Scynexis, Inc. | Methods for the treatment and prevention of ocular disorders |
| US10265265B2 (en) | 2007-03-15 | 2019-04-23 | Drug Delivery Solutions Limited | Topical composition |
| EP2008651A1 (de) | 2007-06-26 | 2008-12-31 | Drug Delivery Solutions Limited | Biologisch erodierbares Patch |
| JP5820722B2 (ja) | 2008-06-06 | 2015-11-24 | スシネキス インク | シクロスポリン類似体及びｈｃｖ感染の治療におけるその使用 |
| US20090306033A1 (en) * | 2008-06-06 | 2009-12-10 | Keqiang Li | Novel cyclic peptides |
| EP2376524B1 (de) * | 2008-12-31 | 2017-03-15 | Cypralis Limited | Derivate von cyclosporin a |
| US8685917B2 (en) * | 2009-07-09 | 2014-04-01 | Enanta Pharmaceuticals, Inc. | Cyclosporin analogues |
| JP2013513595A (ja) * | 2009-12-09 | 2013-04-22 | サイネクシス，インコーポレーテッド | 新規環状ペプチド |
| US9175042B2 (en) * | 2010-10-12 | 2015-11-03 | Allergan, Inc. | Cyclosporin analogs |
| BR112013008864A2 (pt) * | 2010-10-12 | 2016-06-28 | Allergan Inc | análogos d ciclosporina |
| JP6105494B2 (ja) * | 2011-03-14 | 2017-03-29 | ドラッグ デリバリー ソリューションズ リミテッド | 眼科用組成物 |
| US10429712B2 (en) | 2012-04-20 | 2019-10-01 | View, Inc. | Angled bus bar |
| EP2855508B1 (de) | 2012-06-01 | 2018-02-14 | Allergan, Inc. | Cyclosporin-a-analoga |
| WO2014205014A1 (en) | 2013-06-18 | 2014-12-24 | View, Inc. | Electrochromic devices on non-rectangular shapes |
| WO2014210571A1 (en) * | 2013-06-27 | 2014-12-31 | Jing-Feng Huang | Methods and devices for classifying and managing autoimune and inflammatory conditions |
| US9801862B2 (en) | 2013-11-05 | 2017-10-31 | Gustavo A. Garcia-Sánchez | Immunosuppressive treatments, formulations and methods |
| TW201639873A (zh) | 2015-01-08 | 2016-11-16 | 歐樂根公司 | Ｍｅｂｍｔ側鏈已環化之環孢菌素衍生物 |
| KR102084341B1 (ko) * | 2015-12-14 | 2020-03-03 | 요우 핑 차오 | 짧은 합성 펩티드 및 그의 용도 |
| GB201711749D0 (en) * | 2017-07-21 | 2017-09-06 | Cypralis Ltd | Cyclosporin analogues and uses thereof |
| EP3542788A1 (de) | 2018-03-19 | 2019-09-25 | MC2 Therapeutics Limited | Topische zusammensetzung enthaltend calcipotriol und betamethason dipropionat |
| CN111449050A (zh) | 2019-01-20 | 2020-07-28 | 睿诺医疗科技（上海）有限公司 | 环孢菌素类似物及其用途 |
| US20200366476A1 (en) * | 2019-05-17 | 2020-11-19 | Panasonic Avionics Corporation | Transient key negotiation for passenger accessible peripherals |
| CA3152922A1 (en) * | 2019-10-12 | 2021-04-15 | Michael Peel | Treatment and prevention of nephrotoxin-induced kidney injuries |
| CN111920940B (zh) * | 2020-09-16 | 2022-04-05 | 易舟(上海)生物医药有限公司 | 一种眼用制剂及其制备方法和应用 |
| EP4126905A4 (de) | 2020-03-26 | 2024-05-29 | Farsight Medical Technology (Shanghai) Co., Ltd. | Cyclophilinhemmer und verwendungen davon |
| TW202143995A (zh) * | 2020-04-15 | 2021-12-01 | 大陸商睿諾醫療科技（上海）有限公司 | 器官損傷的預防和治療 |
| US11564909B2 (en) * | 2020-11-30 | 2023-01-31 | Romeg Therapeutics Llc | Methods and compositions for oral pilocarpine liquid |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0194972B1 (de) | 1985-03-11 | 1992-07-29 | Sandoz Ag | Cyclosporine |
| US4649047A (en) * | 1985-03-19 | 1987-03-10 | University Of Georgia Research Foundation, Inc. | Ophthalmic treatment by topical administration of cyclosporin |
| US4814323A (en) | 1986-03-25 | 1989-03-21 | Andrieu J M | Process for the treatment and the prevention of AIDS and other disorders induced by the LAV/HTLV III virus |
| US4798823A (en) | 1987-06-03 | 1989-01-17 | Merck & Co., Inc. | New cyclosporin analogs with modified "C-9 amino acids" |
| US4885276A (en) | 1987-06-03 | 1989-12-05 | Merck & Co., Inc. | Cyclosporin analogs with modified "C-9 amino acids" |
| US4996193A (en) | 1989-03-03 | 1991-02-26 | The Regents Of The University Of California | Combined topical and systemic method of administration of cyclosporine |
| US5294604A (en) | 1989-12-20 | 1994-03-15 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method of treating ocular diseases by periocular administration of cyclosporine A or G |
| ATE148469T1 (de) | 1990-11-02 | 1997-02-15 | Sandoz Ag | Zyklosporine |
| US5863550A (en) | 1993-03-31 | 1999-01-26 | Tokyo Tanabe Company Limited | Cholestasis ameliorant |
| US5846964A (en) | 1993-07-19 | 1998-12-08 | Tokyo Tanabe Company Limited | Hepatitis C virus proliferation inhibitor |
| NZ315324A (en) | 1995-07-17 | 1999-10-28 | Chem Ag C | Cyclosporin derivatives with anti-hiv effect |
| JP3089350B2 (ja) | 1995-11-20 | 2000-09-18 | ギルフォード ファーマシューティカルズ インコーポレイテッド | シクロフィリンロタマーゼ活性の阻害剤 |
| FR2757520B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent |
| FR2757521B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2757522B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2762843B1 (fr) | 1997-04-30 | 1999-12-10 | Rhone Poulenc Rorer Sa | Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2772768B1 (fr) | 1997-12-19 | 2000-01-14 | Rhone Poulenc Rorer Sa | Nouveau procede de preparation de derives de cyclosporine |
| CN1205220C (zh) * | 1998-06-12 | 2005-06-08 | 斯－凯穆公司 | 新颖的环孢菌素 |
| FR2780061B1 (fr) | 1998-06-22 | 2001-09-07 | Rhone Poulenc Rorer Sa | Nouveau procede de preparation de derives de cyclosporine |
| USRE40987E1 (en) | 1998-07-01 | 2009-11-17 | Debiopharm S.A. | Cyclosporin with improved activity profile |
| US6254860B1 (en) * | 1999-04-13 | 2001-07-03 | Allergan Sales, Inc. | Ocular treatment using cyclosporin-A derivatives |
| US7229961B2 (en) * | 1999-08-24 | 2007-06-12 | Cellgate, Inc. | Compositions and methods for enhancing drug delivery across and into ocular tissues |
| US6521595B1 (en) | 1999-11-19 | 2003-02-18 | Lg Chemical, Ltd. | Nonimmunosuppressive [γ-hydroxy-methylleucine4] cyclosporin A, hair growth stimulator and external composition for skin using the same |
| HUP0202263A3 (en) | 1999-12-27 | 2003-02-28 | Japan Tobacco Inc | Benzimidazole, indole and imidazo-pyridine derivatives and pharmaceutical compositions containing them |
| CA2410662C (en) | 2000-07-21 | 2012-09-18 | Schering Corporation | Novel peptides as ns3-serine protease inhibitors of hepatitis c virus |
| US6987090B2 (en) | 2002-05-09 | 2006-01-17 | Lg Household & Health Care Ltd. | Use of 3-position cyclosporin derivatives for hair growth |
| KR20040039622A (ko) | 2002-11-04 | 2004-05-12 | 주식회사 엘지생활건강 | 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제 |
| WO2005000308A2 (en) | 2003-05-15 | 2005-01-06 | Rigel Pharmaceuticals, Inc. | Methods of identifying hcv ns5b polymerase inhibitors and use against hepatitis c |
| GB0320638D0 (en) | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
| US20050277584A1 (en) * | 2004-06-09 | 2005-12-15 | Allergan, Inc. | Pharmaceutical compositions comprising cyclosporins |
| CA2573400A1 (en) | 2004-07-13 | 2006-01-19 | Novartis Ag | Cyclosporins to treat alzheimer's disease |
| WO2006005610A1 (en) | 2004-07-14 | 2006-01-19 | Novartis Ag | Use of a combination of cyclosporine and pegylated interferon for treating hepatitis c (hcv) |
| EP1809656A4 (de) * | 2004-09-29 | 2009-03-25 | Amr Technology Inc | Cyclosporinalkinanaloga und deren pharmazeutische anwendungen |
| US7196161B2 (en) | 2004-10-01 | 2007-03-27 | Scynexis Inc. | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection |
| SI1802650T1 (sl) | 2004-10-01 | 2012-03-30 | Scynexis Inc | Eter in tioeter substituirani ciklosporinski derivati za zdravljenje in preventivo pred infekcijami s hepatitisom c |
| AU2005290984B2 (en) | 2004-10-01 | 2010-09-09 | Debiopharm Sa | Use of [D-MeAla]3-[EtVal]4-cyclosporin for the treatment of hepatitis C infection and pharmaceutical composition comprising said [D-MeAla]3-[EtVal]4-cyclosporin |
| CA2587586A1 (en) | 2004-12-23 | 2006-07-06 | Novartis Ag | Compounds for flaviviridae treatment |
| AU2005322242B2 (en) | 2004-12-23 | 2010-02-11 | Novartis Ag | Compositions for HCV treatment |
| BRPI0616476A2 (pt) | 2005-09-30 | 2011-06-21 | Scynexis Inc | uso de uma quantidade terapeuticamente eficaz de um derivado de ciclosporina, e, composição farmacêutica |
| WO2007041631A1 (en) | 2005-09-30 | 2007-04-12 | Scynexis, Inc. | ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION |
| CA2652662C (en) | 2006-05-19 | 2015-11-03 | Scynexis, Inc. | Methods for the treatment and prevention of ocular disorders |
| WO2008069917A2 (en) | 2006-11-20 | 2008-06-12 | Scynexis, Inc. | Novel cyclic peptides |
| US20080255038A1 (en) | 2007-04-11 | 2008-10-16 | Samuel Earl Hopkins | Pharmaceutical compositions |
| WO2008143996A1 (en) * | 2007-05-18 | 2008-11-27 | Scynexis, Inc. | New chemical processes |
| JP5820722B2 (ja) | 2008-06-06 | 2015-11-24 | スシネキス インク | シクロスポリン類似体及びｈｃｖ感染の治療におけるその使用 |
| US20090306033A1 (en) | 2008-06-06 | 2009-12-10 | Keqiang Li | Novel cyclic peptides |
| EP2376524B1 (de) | 2008-12-31 | 2017-03-15 | Cypralis Limited | Derivate von cyclosporin a |
| EP2385838A1 (de) | 2009-01-07 | 2011-11-16 | Scynexis, Inc. | Cyclosporin-derivat zur verwendung bei der behandlung von hcv- und hiv-infektion |
| AU2010203660A1 (en) | 2009-01-07 | 2011-07-28 | Scynexis, Inc | Combination of a cyclosporine derivative and nucleosides for treating HCV |
| JP2013513595A (ja) | 2009-12-09 | 2013-04-22 | サイネクシス，インコーポレーテッド | 新規環状ペプチド |
-
2007
- 2007-05-18 CA CA2652662A patent/CA2652662C/en active Active
- 2007-05-18 DE DE602007013391T patent/DE602007013391D1/de active Active
- 2007-05-18 JP JP2009511089A patent/JP5377293B2/ja active Active
- 2007-05-18 WO PCT/US2007/011919 patent/WO2007136759A2/en active Application Filing
- 2007-05-18 EP EP07795039A patent/EP2023918B1/de active Active
- 2007-05-18 AT AT07795039T patent/ATE502633T1/de active
- 2007-05-18 CN CN2007800267754A patent/CN101511357B/zh active Active
- 2007-05-18 ES ES07795039T patent/ES2361635T3/es active Active
- 2007-05-18 AU AU2007254148A patent/AU2007254148B2/en active Active
- 2007-05-18 DK DK07795039.2T patent/DK2023918T3/da active
- 2007-05-18 US US12/301,210 patent/US8188052B2/en active Active
-
2008
- 2008-11-27 ZA ZA2008/10113A patent/ZA200810113B/en unknown
-
2012
- 2012-04-27 US US13/458,460 patent/US8551952B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20120270804A1 (en) | 2012-10-25 |
| AU2007254148A1 (en) | 2007-11-29 |
| WO2007136759A3 (en) | 2009-04-16 |
| CN101511357A (zh) | 2009-08-19 |
| EP2023918A2 (de) | 2009-02-18 |
| EP2023918B1 (de) | 2011-03-23 |
| JP5377293B2 (ja) | 2013-12-25 |
| AU2007254148B2 (en) | 2013-02-07 |
| CN101511357B (zh) | 2011-11-02 |
| JP2009537550A (ja) | 2009-10-29 |
| DE602007013391D1 (de) | 2011-05-05 |
| WO2007136759A2 (en) | 2007-11-29 |
| US8188052B2 (en) | 2012-05-29 |
| CA2652662C (en) | 2015-11-03 |
| US20100062975A1 (en) | 2010-03-11 |
| ES2361635T3 (es) | 2011-06-20 |
| CA2652662A1 (en) | 2007-11-29 |
| ZA200810113B (en) | 2010-02-24 |
| DK2023918T3 (da) | 2011-04-26 |
| US8551952B2 (en) | 2013-10-08 |
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