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ATE551067T1 - TUMSTATIN FOR THE TREATMENT OF DISEASES RELATED TO REMODELING OF RESPIRATORY TISSUE - Google Patents

TUMSTATIN FOR THE TREATMENT OF DISEASES RELATED TO REMODELING OF RESPIRATORY TISSUE

Info

Publication number
ATE551067T1
ATE551067T1 AT07710533T AT07710533T ATE551067T1 AT E551067 T1 ATE551067 T1 AT E551067T1 AT 07710533 T AT07710533 T AT 07710533T AT 07710533 T AT07710533 T AT 07710533T AT E551067 T1 ATE551067 T1 AT E551067T1
Authority
AT
Austria
Prior art keywords
tumstatin
remodeling
treatment
diseases related
respiratory tissue
Prior art date
Application number
AT07710533T
Other languages
German (de)
Inventor
Sarah Boustany
Janette Burgess
Judith Black
Brian Oliver
Original Assignee
Crc For Asthma And Airways Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crc For Asthma And Airways Ltd filed Critical Crc For Asthma And Airways Ltd
Application granted granted Critical
Publication of ATE551067T1 publication Critical patent/ATE551067T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides a method for improving airway conductance in a subject in need thereof, the method com prising administering to the subject an effective amount of one or more of tumstatin; a derivative, variant or homologue thereof; a polynucleotide encoding tumstatin or a derivative, variant or homologue thereof; or an agent capable of increasing the expression or production of tumstatin.
AT07710533T 2006-02-03 2007-02-02 TUMSTATIN FOR THE TREATMENT OF DISEASES RELATED TO REMODELING OF RESPIRATORY TISSUE ATE551067T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76483306P 2006-02-03 2006-02-03
PCT/AU2007/000106 WO2007087689A1 (en) 2006-02-03 2007-02-02 A method of modulating cellular activity and agents for use therein

Publications (1)

Publication Number Publication Date
ATE551067T1 true ATE551067T1 (en) 2012-04-15

Family

ID=38327093

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07710533T ATE551067T1 (en) 2006-02-03 2007-02-02 TUMSTATIN FOR THE TREATMENT OF DISEASES RELATED TO REMODELING OF RESPIRATORY TISSUE

Country Status (5)

Country Link
US (2) US8227419B2 (en)
EP (2) EP1988915B1 (en)
AT (1) ATE551067T1 (en)
AU (1) AU2007211846B2 (en)
WO (1) WO2007087689A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120190612A1 (en) * 2009-06-09 2012-07-26 Crc For Asthma And Airways Ltd. Methods of treatment
CN105148269A (en) 2011-02-21 2015-12-16 菲布他丁有限合伙公司 Methods for treating and diagnosing disease
WO2013025846A2 (en) 2011-08-17 2013-02-21 The Regents Of The University Of Colorado, A Body Corporate Transferrin-tumstatin fusion protein and methods for producing and using the same
WO2016144815A1 (en) * 2015-03-06 2016-09-15 Georgia State University Research Foundation, Inc. Integrin-targeting protein and methods of use thereof
GB201721387D0 (en) * 2017-12-20 2018-01-31 Nordic Bioscience As Tumstatin assay

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4019653A (en) 1975-08-22 1977-04-26 Graco Inc. Automatic proportioning paint spray system
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4849338A (en) 1982-07-16 1989-07-18 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4843000A (en) 1979-12-26 1989-06-27 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4424279A (en) 1982-08-12 1984-01-03 Quidel Rapid plunger immunoassay method and apparatus
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5723218A (en) 1990-04-16 1998-03-03 Molecular Probes, Inc. Dipyrrometheneboron difluoride labeled flourescent microparticles
US5459276A (en) 1994-05-20 1995-10-17 Molecular Probes, Inc. Benzazolylcoumarin-based ion indicators for heavy metals
US5326692B1 (en) 1992-05-13 1996-04-30 Molecular Probes Inc Fluorescent microparticles with controllable enhanced stokes shift
US5227487A (en) 1990-04-16 1993-07-13 Molecular Probes, Inc. Certain tricyclic and pentacyclic-hetero nitrogen rhodol dyes
US5405975A (en) 1993-03-29 1995-04-11 Molecular Probes, Inc. Fluorescent ion-selective diaryldiaza crown ether conjugates
US5648270A (en) 1995-02-06 1997-07-15 Molecular Probes, Inc. Methods of sensing with fluorescent conjugates of metal-chelating nitrogen heterocycles
US5453517A (en) 1992-02-25 1995-09-26 Molecular Probes, Inc. Reactive derivatives of bapta used to make ion-selective chelators
US5274113A (en) 1991-11-01 1993-12-28 Molecular Probes, Inc. Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates
US5433896A (en) 1994-05-20 1995-07-18 Molecular Probes, Inc. Dibenzopyrrometheneboron difluoride dyes
EP0773227A1 (en) 1991-09-18 1997-05-14 Affymax Technologies N.V. Diverse collections of oligomers in use to prepare drugs, diagnostic reagents, pesticides or herbicides
US5763263A (en) 1995-11-27 1998-06-09 Dehlinger; Peter J. Method and apparatus for producing position addressable combinatorial libraries
US5753187A (en) 1996-06-14 1998-05-19 Stovall Life Science, Inc. Combinatorial chemistry cassette
US7387779B2 (en) * 1998-06-17 2008-06-17 Beth Israel Deaconess Medical Center Anti-angiogenic proteins and fragments and methods of use thereof
AU4187200A (en) 1999-04-01 2000-10-23 Biostratum, Inc. The use of domains of type iv collagen t inhibit angiogenesis an tumour growth
JP2003519630A (en) * 2000-01-07 2003-06-24 ベス イスラエル ディーコネス メディカル センター Anti-angiogenic proteins and fragments thereof and methods of use
WO2005103281A2 (en) * 2004-04-26 2005-11-03 Children's Medical Center Corporation Platelet biomarkers for the detection of disease
EP1812030A4 (en) * 2004-10-14 2009-01-14 Sopherion Therapeutics Inc Anti-angiogenic peptides and methods of use thereof
WO2006128027A1 (en) * 2005-05-26 2006-11-30 Peptx, Inc. Functionally active recombinant peptides, methods for producing same and interactions with other peptides
JP2009512423A (en) * 2005-09-12 2009-03-26 ザ・ジョンズ・ホプキンス・ユニバーシティ Composition having anti-angiogenic activity and use thereof

Also Published As

Publication number Publication date
AU2007211846A1 (en) 2007-08-09
EP2468294A1 (en) 2012-06-27
EP1988915A1 (en) 2008-11-12
EP1988915B1 (en) 2012-03-28
US20090221494A1 (en) 2009-09-03
US8227419B2 (en) 2012-07-24
EP1988915A4 (en) 2009-11-11
AU2007211846B2 (en) 2013-05-23
US20120283192A1 (en) 2012-11-08
WO2007087689A1 (en) 2007-08-09

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