ATE540973T1 - Zusammensetzungen und verfahren zur verwendung von mgd-cdf zur krankheitsbehandlung - Google Patents
Zusammensetzungen und verfahren zur verwendung von mgd-cdf zur krankheitsbehandlungInfo
- Publication number
- ATE540973T1 ATE540973T1 AT05791762T AT05791762T ATE540973T1 AT E540973 T1 ATE540973 T1 AT E540973T1 AT 05791762 T AT05791762 T AT 05791762T AT 05791762 T AT05791762 T AT 05791762T AT E540973 T1 ATE540973 T1 AT E540973T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- compositions
- mgd
- cdf
- disease treatment
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/243—Colony Stimulating Factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Pregnancy & Childbirth (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Nutrition Science (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59056504P | 2004-07-22 | 2004-07-22 | |
US64760405P | 2005-01-27 | 2005-01-27 | |
US66493205P | 2005-03-24 | 2005-03-24 | |
US69901905P | 2005-07-14 | 2005-07-14 | |
PCT/US2005/025941 WO2006012451A2 (en) | 2004-07-22 | 2005-07-21 | Compositions and methods of use for mgd-csf in disease treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE540973T1 true ATE540973T1 (de) | 2012-01-15 |
Family
ID=35448388
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05791762T ATE540973T1 (de) | 2004-07-22 | 2005-07-21 | Zusammensetzungen und verfahren zur verwendung von mgd-cdf zur krankheitsbehandlung |
Country Status (7)
Country | Link |
---|---|
US (4) | US20070264277A1 (de) |
EP (3) | EP1778842B8 (de) |
JP (4) | JP5435865B2 (de) |
AT (1) | ATE540973T1 (de) |
AU (1) | AU2005267062C1 (de) |
CA (1) | CA2574654C (de) |
WO (1) | WO2006012451A2 (de) |
Families Citing this family (41)
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US9060961B2 (en) * | 2006-11-09 | 2015-06-23 | University Of Washington | Molecules and methods for treatment and detection of cancer |
EP2271358B1 (de) * | 2008-03-25 | 2018-11-21 | Amarantus Therapeutics, Inc. | verwendung von mesencephalischem von Astrozyten abstammenden neurotrophen Faktor zur Behandlung von Parkinsonscher Erkrankung |
WO2009137631A2 (en) * | 2008-05-07 | 2009-11-12 | Wintherix Llc | Methods for identifying compounds that affect expression of cancer-related protein isoforms |
WO2010062399A2 (en) | 2008-11-26 | 2010-06-03 | Five Prime Therapeutics, Inc. | Csf1r extracellular domain fusion molecules and treatments using same |
US8183207B2 (en) | 2008-11-26 | 2012-05-22 | Five Prime Therapeutics, Inc. | Treatment of osteolytic disorders and cancer using CSF1R extracellular domain fusion molecules |
DK2949670T3 (da) | 2009-12-10 | 2019-05-13 | Hoffmann La Roche | Antistoffer, der fortrinsvis binder humant ekstracellulært CSF1R-domæne 4 og anvendelse deraf |
MX336682B (es) | 2010-03-05 | 2016-01-27 | Hoffmann La Roche | Anticuerpos contra csf-1r humanos y usos de los mismos. |
EP2542587A1 (de) | 2010-03-05 | 2013-01-09 | F. Hoffmann-La Roche AG | Antikörper gegen menschlichen csf-1r und ihre verwendung |
KR101838698B1 (ko) | 2010-05-04 | 2018-03-16 | 파이브 프라임 테라퓨틱스, 인크. | Csf1r에 결합하는 항체들 |
US20110312506A1 (en) * | 2010-06-17 | 2011-12-22 | Dilyx Biotechnologies, LLC | Methods and kits for screening protein solubility |
US10023643B2 (en) | 2011-12-15 | 2018-07-17 | Hoffmann-La Roche Inc. | Antibodies against human CSF-1R and uses thereof |
US20130302322A1 (en) | 2012-05-11 | 2013-11-14 | Five Prime Therapeutics, Inc. | Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r) |
SG10201906328RA (en) | 2012-08-31 | 2019-08-27 | Five Prime Therapeutics Inc | Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r) |
US20150329639A1 (en) * | 2012-12-12 | 2015-11-19 | University Of Virginia Patent Foundation | Compositions and methods for regulating erythropoiesis |
AR095882A1 (es) | 2013-04-22 | 2015-11-18 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9 |
AR097584A1 (es) | 2013-09-12 | 2016-03-23 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano |
WO2015129263A1 (ja) | 2014-02-25 | 2015-09-03 | 株式会社クラレ | スフェロイド作製用デバイス、スフェロイドの回収方法及び製造方法 |
US11175268B2 (en) | 2014-06-09 | 2021-11-16 | Biometry Inc. | Mini point of care gas chromatographic test strip and method to measure analytes |
AU2015274801B2 (en) | 2014-06-09 | 2020-10-15 | Biometry Inc. | Low cost test strip and method to measure analyte |
JP6964410B2 (ja) | 2014-06-23 | 2021-11-10 | ファイヴ プライム セラピューティクス インク | コロニー刺激因子1受容体(csf1r)に結合する抗体で疾患を治療する方法 |
US20160060597A1 (en) * | 2014-08-28 | 2016-03-03 | The University Of Maryland, Baltimore | Functional myelination of neurons |
DK3212670T3 (da) | 2014-10-29 | 2021-03-22 | Five Prime Therapeutics Inc | Kombinationsterapi mod cancer |
EP3215847A4 (de) * | 2014-11-03 | 2018-02-14 | Bioincept LLC | Pif-bindung als ein marker zur immundysregulierung |
AU2015369854B2 (en) | 2014-12-22 | 2021-07-01 | Five Prime Therapeutics, Inc. | Anti-CSF1R antibodies for treating PVNS |
EP3283527B1 (de) | 2015-04-13 | 2021-01-13 | Five Prime Therapeutics, Inc. | Kombinationstherapie gegen krebs |
US11255840B2 (en) | 2016-07-19 | 2022-02-22 | Biometry Inc. | Methods of and systems for measuring analytes using batch calibratable test strips |
EP3504239B1 (de) | 2016-08-25 | 2024-05-29 | F. Hoffmann-La Roche AG | Intervalldosierung eines anti-csf-1r-antikörpers in kombination mit makrophagenaktivierungsmittel |
CN110072553B (zh) | 2016-12-22 | 2023-09-15 | 豪夫迈·罗氏有限公司 | 在抗pd-l1/pd1治疗失败之后抗csf-1r抗体与抗pd-l1抗体组合对肿瘤的治疗 |
WO2018133937A1 (en) * | 2017-01-19 | 2018-07-26 | Biontech Ag | Engineered cells for inducing tolerance |
CN107130009A (zh) * | 2017-07-13 | 2017-09-05 | 华南理工大学 | 一种具有免疫活性和抗红细胞溶血活性的新型多肽及其制备方法 |
JP2020535119A (ja) | 2017-09-13 | 2020-12-03 | ファイヴ プライム セラピューティクス インク | 膵臓がんの抗csf1rおよび抗pd−1抗体組合せ併用療法 |
CN109456989B (zh) * | 2018-10-31 | 2022-03-29 | 陕西慧康生物科技有限责任公司 | 一种提高毕赤酵母分泌表达的载体的构建方法 |
CN109593126B (zh) * | 2018-11-28 | 2019-11-22 | 山西锦波生物医药股份有限公司 | 多肽、其生产方法和用途 |
CN109468361B (zh) * | 2018-11-29 | 2021-11-02 | 电子科技大学 | 鱼类自然杀伤细胞杀伤细菌感染的单核/巨噬细胞能力的测定方法 |
CN109596839A (zh) * | 2018-12-25 | 2019-04-09 | 广州万孚生物技术股份有限公司 | 人和肽素快速定量检测方法与试剂盒 |
CN113508129B (zh) * | 2019-01-15 | 2025-02-18 | 法国国家健康和医学研究院 | 突变的白介素-34(il-34)多肽及其在治疗中的用途 |
CN111150841B (zh) * | 2019-12-31 | 2023-08-15 | 优锐生物医药科技(深圳)有限公司 | 一种主动免疫调控微粒及其制备方法和应用 |
CN114113602B (zh) * | 2020-08-28 | 2024-07-02 | 香港城市大学深圳研究院 | 免疫球蛋白相关凝血因子x作为急性心肌梗死的生物标志物 |
US20240335562A1 (en) * | 2021-08-04 | 2024-10-10 | Alpine Biotherapeutics Corporation | Sustainable ocular cell-mediated intraocular delivery of cellular therapeutics for treatment of ocular diseases or disorders |
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2005
- 2005-07-21 WO PCT/US2005/025941 patent/WO2006012451A2/en active Application Filing
- 2005-07-21 CA CA2574654A patent/CA2574654C/en not_active Expired - Fee Related
- 2005-07-21 AU AU2005267062A patent/AU2005267062C1/en not_active Ceased
- 2005-07-21 US US11/632,319 patent/US20070264277A1/en not_active Abandoned
- 2005-07-21 EP EP05791762A patent/EP1778842B8/de not_active Ceased
- 2005-07-21 JP JP2007522769A patent/JP5435865B2/ja not_active Expired - Fee Related
- 2005-07-21 EP EP20100179665 patent/EP2287310B1/de not_active Not-in-force
- 2005-07-21 EP EP12150386.6A patent/EP2479277B1/de not_active Not-in-force
- 2005-07-21 AT AT05791762T patent/ATE540973T1/de active
-
2009
- 2009-02-12 US US12/370,559 patent/US8178109B2/en not_active Expired - Fee Related
-
2012
- 2012-04-13 US US13/446,254 patent/US8575312B2/en not_active Expired - Fee Related
-
2013
- 2013-10-08 US US14/048,834 patent/US20140170145A1/en not_active Abandoned
- 2013-10-31 JP JP2013226693A patent/JP5815638B2/ja not_active Expired - Fee Related
-
2015
- 2015-02-18 JP JP2015029580A patent/JP2015133970A/ja active Pending
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2016
- 2016-05-24 JP JP2016103092A patent/JP2016146850A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20110003384A1 (en) | 2011-01-06 |
HK1100223A1 (en) | 2007-09-14 |
JP2016146850A (ja) | 2016-08-18 |
US20140170145A1 (en) | 2014-06-19 |
EP2287310B1 (de) | 2015-05-06 |
JP5815638B2 (ja) | 2015-11-17 |
EP1778842A2 (de) | 2007-05-02 |
JP2014034577A (ja) | 2014-02-24 |
US20120258071A1 (en) | 2012-10-11 |
JP2008507283A (ja) | 2008-03-13 |
JP2015133970A (ja) | 2015-07-27 |
CA2574654A1 (en) | 2006-02-02 |
EP2479277B1 (de) | 2015-09-02 |
AU2005267062C1 (en) | 2013-01-17 |
EP2287310A1 (de) | 2011-02-23 |
WO2006012451A3 (en) | 2006-03-30 |
JP5435865B2 (ja) | 2014-03-05 |
EP1778842B8 (de) | 2012-03-21 |
AU2005267062B2 (en) | 2012-05-17 |
US8178109B2 (en) | 2012-05-15 |
AU2005267062A1 (en) | 2006-02-02 |
US20070264277A1 (en) | 2007-11-15 |
CA2574654C (en) | 2014-02-18 |
EP2479277A2 (de) | 2012-07-25 |
HK1167432A1 (en) | 2012-11-30 |
EP1778842B1 (de) | 2012-01-11 |
US8575312B2 (en) | 2013-11-05 |
WO2006012451A2 (en) | 2006-02-02 |
EP2479277A3 (de) | 2012-08-22 |
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