Nothing Special   »   [go: up one dir, main page]

ATE429423T1 - Neue zwischenprodukte für linezolid und verwandte verbindungen - Google Patents

Neue zwischenprodukte für linezolid und verwandte verbindungen

Info

Publication number
ATE429423T1
ATE429423T1 AT04770673T AT04770673T ATE429423T1 AT E429423 T1 ATE429423 T1 AT E429423T1 AT 04770673 T AT04770673 T AT 04770673T AT 04770673 T AT04770673 T AT 04770673T AT E429423 T1 ATE429423 T1 AT E429423T1
Authority
AT
Austria
Prior art keywords
fluoro
linezolid
morpholinyl
related compounds
intermediate products
Prior art date
Application number
AT04770673T
Other languages
English (en)
Inventor
Rao Dodda Mohan
Reddy Pingili Krishna
Original Assignee
Symed Labs Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35784913&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE429423(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Symed Labs Ltd filed Critical Symed Labs Ltd
Application granted granted Critical
Publication of ATE429423T1 publication Critical patent/ATE429423T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT04770673T 2004-07-20 2004-07-20 Neue zwischenprodukte für linezolid und verwandte verbindungen ATE429423T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2004/000218 WO2006008754A1 (en) 2004-07-20 2004-07-20 Novel intermediates for linezolid and related compounds

Publications (1)

Publication Number Publication Date
ATE429423T1 true ATE429423T1 (de) 2009-05-15

Family

ID=35784913

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04770673T ATE429423T1 (de) 2004-07-20 2004-07-20 Neue zwischenprodukte für linezolid und verwandte verbindungen

Country Status (7)

Country Link
US (1) US7429661B2 (de)
EP (1) EP1768967B1 (de)
AT (1) ATE429423T1 (de)
DE (1) DE602004020812D1 (de)
ES (1) ES2325401T3 (de)
PL (1) PL1768967T3 (de)
WO (1) WO2006008754A1 (de)

Families Citing this family (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1673370E (pt) 2003-10-16 2009-11-05 Symed Labs Ltd Forma cristalina de linezolida
ES2294494T3 (es) * 2004-04-19 2008-04-01 Symed Labs Limited Un nuevo procedimiento para la preparacion de linezolid y compuestos relacionados.
CN102442970A (zh) 2006-05-31 2012-05-09 雅培制药有限公司 用作大麻素受体配位体的噻唑化合物及其用途
CA2647598A1 (en) 2006-05-31 2007-12-06 Abbott Laboratories Compounds as cannabinoid receptor ligands and uses thereof
US8841334B2 (en) 2006-05-31 2014-09-23 Abbvie Inc. Compounds as cannabinoid receptor ligands and uses thereof
US7875640B2 (en) 2007-03-28 2011-01-25 Abbott Laboratories Compounds as cannabinoid receptor ligands
US7872033B2 (en) 2007-04-17 2011-01-18 Abbott Laboratories Compounds as cannabinoid receptor ligands
US8501794B2 (en) 2007-04-17 2013-08-06 Abbvie Inc. Compounds as cannabinoid receptor ligands
WO2008144360A1 (en) 2007-05-18 2008-11-27 Abbott Laboratories Novel compounds as cannabinoid receptor ligands
US9193713B2 (en) 2007-10-12 2015-11-24 Abbvie Inc. Compounds as cannabinoid receptor ligands
MX2010010023A (es) 2008-03-11 2010-11-30 Abbott Lab Compuestos novedosos como ligandos receptores de canabinoides.
MX2010010773A (es) 2008-04-01 2011-04-11 Abbott Gmbh & Co Kg Tetrahidroisoquinolinas, composiciones farmaceuticas que las contienen y su uso en terapia.
CA2731102A1 (en) 2008-08-15 2010-02-18 Abbott Laboratories Imine derivatives as cannabinoid receptor ligands
US8846730B2 (en) 2008-09-08 2014-09-30 Abbvie Inc. Compounds as cannabinoid receptor ligands
KR20110061619A (ko) 2008-09-16 2011-06-09 아보트 러보러터리즈 칸나비노이드 수용체 리간드로서의 치환된 벤즈아미드
MX2011004090A (es) 2008-10-17 2011-05-31 Abbott Lab Antagonistas trpv1.
US8604053B2 (en) 2008-10-17 2013-12-10 Abbvie Inc. TRPV1 antagonists
US20100160322A1 (en) 2008-12-04 2010-06-24 Abbott Laboratories Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
US8557983B2 (en) 2008-12-04 2013-10-15 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
UA108193C2 (uk) 2008-12-04 2015-04-10 Апоптозіндукуючий засіб для лікування раку і імунних і аутоімунних захворювань
JP5684720B2 (ja) 2008-12-05 2015-03-18 アッヴィ・インコーポレイテッド 癌および免疫疾患の治療のためのｂｃｌ−２−選択的アポトーシス誘発剤としてのスルホンアミド誘導体
US8586754B2 (en) 2008-12-05 2013-11-19 Abbvie Inc. BCL-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
US8563735B2 (en) 2008-12-05 2013-10-22 Abbvie Inc. Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
PA8854001A1 (es) 2008-12-16 2010-07-27 Abbott Lab Compuestos novedosos como ligandos de receptores de canabinoides
CN101774978B (zh) 2009-01-13 2011-09-21 联化科技股份有限公司 一种利奈唑胺的制备方法及其中间体
KR20110116161A (ko) 2009-01-19 2011-10-25 아보트 러보러터리즈 암, 면역 질환 및 자가면역 질환의 치료를 위한 아폽토시스-유도제
DK2511264T3 (da) 2009-01-19 2015-06-22 Abbvie Inc Apoptose-inducerende midler til behandling af cancer og immunsygdomme og autoimmune sygdomme
TW201038569A (en) 2009-02-16 2010-11-01 Abbott Gmbh & Co Kg Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy
AR075442A1 (es) 2009-02-16 2011-03-30 Abbott Gmbh & Co Kg Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia
TWI519530B (zh) 2009-02-20 2016-02-01 艾伯維德國有限及兩合公司 羰醯胺化合物及其作為鈣蛋白酶（ｃａｌｐａｉｎ）抑制劑之用途
US8288428B2 (en) 2009-03-27 2012-10-16 Abbott Laboratories Compounds as cannabinoid receptor ligands
WO2010111574A1 (en) 2009-03-27 2010-09-30 Abbott Laboratories Compounds as cannabinoid receptor ligands
US8492371B2 (en) 2009-03-27 2013-07-23 Abbvie Inc. Compounds as cannabinoid receptor ligands
US8507493B2 (en) 2009-04-20 2013-08-13 Abbvie Inc. Amide and amidine derivatives and uses thereof
US8236798B2 (en) 2009-05-07 2012-08-07 Abbott Gmbh & Co. Kg Carboxamide compounds and their use as calpain inhibitors
RU2535347C3 (ru) 2009-05-26 2019-05-14 ЭббВи Айэленд Анлимитед Компани Индуцирующие апоптоз средства для лечения злокачественной опухоли и иммунных и аутоиммунных заболеваний
US9034875B2 (en) 2009-05-26 2015-05-19 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
US8546399B2 (en) 2009-05-26 2013-10-01 Abbvie Inc. Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
US20220315555A1 (en) 2009-05-26 2022-10-06 Abbvie Inc. Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
US8962639B2 (en) 2009-05-29 2015-02-24 Abbvie Inc. Potassium channel modulators
WO2011053740A1 (en) 2009-10-28 2011-05-05 Belkin International, Inc. Portable multi-media communication device protective carrier and method of manufacture therefor
JP2013512241A (ja) 2009-11-25 2013-04-11 アボット・ラボラトリーズ カリウムチャネルモジュレーター
TW201130855A (en) 2009-12-16 2011-09-16 Abbott Lab Prodrug compounds useful as cannabinoid ligands
EP2516408A1 (de) 2009-12-26 2012-10-31 Alembic Pharmaceuticals Limited Verfahren zur herstellung von linezolid
CN102947283B (zh) 2010-03-25 2015-10-07 Abbvie公司 用于治疗癌症和免疫以及自身免疫性疾病的细胞凋亡诱导剂
KR20130108975A (ko) 2010-04-30 2013-10-07 인디애나 유니버시티 리서치 앤드 테크놀로지 코포레이션 리네졸리드의 제조 방법
TWI520960B (zh) 2010-05-26 2016-02-11 艾伯維有限公司 用於治療癌症及免疫及自體免疫疾病之細胞凋亡誘導劑
US8586596B2 (en) 2010-06-15 2013-11-19 Abbvie Inc. Compounds as cannabinoid receptor ligands
CN102311400A (zh) * 2010-06-29 2012-01-11 翔真生物科技股份有限公司 制备5-左旋-氨甲基-3-芳基-2-恶唑烷酮类的方法
CN103140476A (zh) 2010-08-10 2013-06-05 Abbvie公司 新颖的trpv3调节剂
EP2603505A1 (de) 2010-08-11 2013-06-19 Synthon BV Verfahren zur herstellung von linezolid
EP2690100A1 (de) 2010-08-11 2014-01-29 Synhton B.V. Verfahren zur Linezpolid Herstellung
US8877794B2 (en) 2010-08-13 2014-11-04 Abbott Laboratories Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US8846743B2 (en) 2010-08-13 2014-09-30 Abbott Laboratories Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
US9045459B2 (en) 2010-08-13 2015-06-02 AbbVie Deutschland GmbH & Co. KG Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9051280B2 (en) 2010-08-13 2015-06-09 AbbVie Deutschland GmbH & Co. KG Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US8883839B2 (en) 2010-08-13 2014-11-11 Abbott Laboratories Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
AU2011300365A1 (en) 2010-09-07 2013-05-02 Symed Labs Limited Processes for the preparation of 4-{4-[5(S)-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl} morpholin-3-one
CN103119035B (zh) 2010-09-27 2015-09-30 雅培股份有限两合公司 杂环化合物和它们作为糖原合成酶激酶-3抑制剂的用途
SG189471A1 (en) 2010-10-29 2013-05-31 Abbvie Inc Solid dispersions containing an apoptosis-inducing agent
UA113500C2 (xx) 2010-10-29 2017-02-10 Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
WO2012059432A1 (en) 2010-11-01 2012-05-10 Abbott Gmbh & Co. Kg N-phenyl-(homo)piperazinyl-benzenesulfonyl or benzenesulfonamide compounds suitable for treating disorders that respond to the modulation of the 5-ht6 receptor
WO2012059431A1 (en) 2010-11-01 2012-05-10 Abbott Gmbh & Co. Kg Benzenesulfonyl or sulfonamide compounds suitable for treating disorders that respond to the modulation of the serotonin 5-ht6 receptor
WO2012067963A1 (en) 2010-11-15 2012-05-24 Abbott Laboratories Nampt inhibitors
MX2013005454A (es) 2010-11-15 2013-06-24 Abbvie Inc Inhibidores de nampt y rock.
US8609669B2 (en) 2010-11-16 2013-12-17 Abbvie Inc. Potassium channel modulators
WO2012067824A1 (en) 2010-11-16 2012-05-24 Abbott Laboratories Potassium channel modulators
DK2642999T3 (en) 2010-11-23 2017-01-09 Abbvie Ireland Unlimited Co METHODS OF TREATMENT FOR USING selectivity-VE BCL-2 INHIBITORS
RU2628560C2 (ru) 2010-11-23 2017-08-18 Эббви Инк. Соли и кристаллические формы индуцирующего апоптоз агента
US9090592B2 (en) 2010-12-30 2015-07-28 AbbVie Deutschland GmbH & Co. KG Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
CN103391927A (zh) 2011-02-24 2013-11-13 李药业有限公司 利奈唑胺及其新中间体的新制备方法
US8802693B1 (en) 2011-03-09 2014-08-12 Abbvie Inc. Azaadamantane derivatives and methods of use
WO2012129491A1 (en) 2011-03-24 2012-09-27 Abbott Laboratories Trpv3 modulators
CA2831146C (en) 2011-03-25 2019-06-04 Abbvie Inc. Trpv1 antagonists
WO2012140061A1 (en) * 2011-04-11 2012-10-18 Sandoz Ag Method for the preparation of substituted oxazolidinones
CN102229577A (zh) * 2011-05-11 2011-11-02 石药集团中诺药业（石家庄）有限公司 利奈唑胺中间体的制备及纯化方法
US9309200B2 (en) 2011-05-12 2016-04-12 AbbVie Deutschland GmbH & Co. KG Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy
WO2012158399A1 (en) 2011-05-13 2012-11-22 Abbott Laboratories Condensed 2 - carbamoylpyridazinones as potassium channel modulators
CN102304125B (zh) * 2011-07-05 2014-02-19 浙江亚太药业股份有限公司 一种用于制备利奈唑胺的中间体
WO2013020930A1 (en) 2011-08-05 2013-02-14 Abbott Gmbh & Co. Kg Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy
EP2753619A2 (de) 2011-09-08 2014-07-16 Cadila Healthcare Limited Verfahren und zwischenprodukte zur herstellung von rivaroxaban
TWI561521B (en) 2011-10-14 2016-12-11 Abbvie Inc Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
TWI571466B (zh) 2011-10-14 2017-02-21 艾伯維有限公司 用於治療癌症及免疫與自體免疫疾病之細胞凋亡誘發劑
WO2013062966A2 (en) 2011-10-24 2013-05-02 Abbvie Inc. Novel trpv3 modulators
US20130116241A1 (en) 2011-11-09 2013-05-09 Abbvie Inc. Novel inhibitor compounds of phosphodiesterase type 10a
CN103103229B (zh) * 2011-11-15 2015-03-18 安琪酵母股份有限公司 一种利奈唑酮中间体的合成方法
US8846741B2 (en) 2011-11-18 2014-09-30 Abbvie Inc. N-substituted aminobenzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy
WO2013096223A1 (en) 2011-12-19 2013-06-27 Abbvie Inc. Trpv1 antagonists
US8969325B2 (en) 2011-12-19 2015-03-03 Abbvie Inc. TRPV1 antagonists
US9365512B2 (en) 2012-02-13 2016-06-14 AbbVie Deutschland GmbH & Co. KG Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy
WO2013149376A1 (en) 2012-04-02 2013-10-10 Abbott Laboratories Chemokine receptor antagonists
CA2870931A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Isoindolone derivatives
EP2850081A1 (de) 2012-05-11 2015-03-25 AbbVie Inc. Thiazolcarboxamidderivate zur verwendung als nampt-hemmer
US9193723B2 (en) 2012-05-11 2015-11-24 Abbvie Inc. NAMPT inhibitors
CA2873075A1 (en) 2012-05-11 2013-07-14 Abbvie Inc. Nampt inhibitors
MX2014013751A (es) 2012-05-11 2015-08-07 Abbvie Inc Piridazina y derivados de piridina como inhibidores de nampt.
US20130317055A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Neuronal nicotinic agonist and methods of use
US20130317054A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Neuronal nicotinic agonist and methods of use
CN103420933B (zh) * 2012-05-26 2016-03-02 鲁南制药集团股份有限公司 一种利奈唑胺的制备方法
SG11201408324QA (en) 2012-06-12 2015-01-29 Abbvie Inc Pyridinone and pyridazinone derivatives
US8796328B2 (en) 2012-06-20 2014-08-05 Abbvie Inc. TRPV1 antagonists
CN103570639B (zh) * 2012-08-08 2016-02-03 成都国弘医药有限公司 一种利奈唑胺的合成方法
US20140080813A1 (en) 2012-09-14 2014-03-20 AbbVie Deutschland GmbH & Co. KG Tricyclic quinoline and quinoxaline derivatives
JP6290217B2 (ja) 2012-09-14 2018-03-07 アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー 三環式キノリンおよびキノキサリン誘導体
CN102887871B (zh) * 2012-09-26 2015-12-02 苏州敬业医药化工有限公司 3-取代苯基-5-氨甲基噁唑烷-2-酮的制备方法
WO2014071990A1 (en) 2012-11-09 2014-05-15 Synthon Bv Process for making linezolid
MX2015012386A (es) 2013-03-13 2016-02-03 Abbvie Inc Inhibidores de la cinasa cdk9.
JP2016516710A (ja) 2013-03-13 2016-06-09 アッヴィ・インコーポレイテッド ピリジン系ｃｄｋ９キナーゼ阻害薬
US9593104B2 (en) 2013-03-14 2017-03-14 Benova Labs Pvt. Limited Process for the preparation of oxazolidinone derivatives
BR112015023016A2 (pt) 2013-03-14 2017-07-18 Abbvie Deutschland derivados de oxindolo carregando um substituinte oxetano e uso do mesmo para tratamento de doenças relacionadas a vasopressina
JP2016510788A (ja) 2013-03-14 2016-04-11 アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー ホスホジエステラーゼ１０ａ型の新規な阻害剤化合物
US9346813B2 (en) 2013-03-14 2016-05-24 Abbvie Inc. Substituted pyrrolo[2,3-d]pyrimindines as CDK9 kinase inhibitors
US9796708B2 (en) 2013-03-14 2017-10-24 Abbvie Inc. Pyrrolo [2,3-B] pyridine CDK9 kinase inhibitors
US20140275082A1 (en) 2013-03-14 2014-09-18 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
TW201444836A (zh) 2013-03-14 2014-12-01 Abbvie Inc 吡咯并［２，３－ｂ］吡啶ｃｄｋ９激酶抑制劑
US9650334B2 (en) 2013-03-15 2017-05-16 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9656955B2 (en) 2013-03-15 2017-05-23 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9586913B2 (en) 2013-04-25 2017-03-07 Symed Labs Limited Processes for the preparation of linezolid using novel intermediates
CA2924699A1 (en) 2013-10-17 2015-04-23 AbbVie Deutschland GmbH & Co. KG Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
EP3057960B1 (de) 2013-10-17 2019-02-27 AbbVie Deutschland GmbH & Co. KG Aminochroman-, aminothiochroman- und amino-1,2,3,4-tetrahydrochinolin-derivate, pharmazeutische zusammensetzungen damit und verwendung in der therapie
US9840495B2 (en) 2013-12-20 2017-12-12 AbbVie Deutschland GmbH & Co. KG Oxindole derivatives carrying a piperidyl-substituted azetidinyl substituent and use thereof for treating vasopressine-related diseases
US9328112B2 (en) 2014-02-06 2016-05-03 Abbvie Inc. Tetracyclic CDK9 kinase inhibitors
EP3143023B1 (de) 2014-05-15 2018-04-11 AbbVie Deutschland GmbH & Co. KG Oxindolverbindungen mit einem co-gebundenen spirosubstituenten und verwendung davon zur behandlung von vasopressinvermittelten erkrankungen
CN105315231A (zh) * 2014-06-11 2016-02-10 成都自豪药业有限公司 利奈唑胺相关物质的制备方法
US9617226B2 (en) 2014-09-05 2017-04-11 AbbVie Deutschland GmbH & Co. KG Fused heterocyclic or carbocyclic compounds carrying a substituted cycloaliphatic radical and use thereof for treating vasopressin-related diseases
US9550754B2 (en) 2014-09-11 2017-01-24 AbbVie Deutschland GmbH & Co. KG 4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy
US20180243298A1 (en) 2015-04-02 2018-08-30 Abbvie Inc. Trpv3 modulators
WO2017089458A1 (en) 2015-11-25 2017-06-01 AbbVie Deutschland GmbH & Co. KG Hexahydropyrazinobenz- or -pyrido-oxazepines carrying an oxygen-containing substituent and use thereof in the treatment of 5-ht2c-dependent disorders
CN105566242B (zh) * 2016-01-12 2017-12-05 江苏豪森药业集团有限公司 利奈唑胺及其中间体的制备方法
US9643939B1 (en) 2016-04-18 2017-05-09 Optimus Drugs Private Limited Process for the preparation of linezolid
USRE47606E1 (en) 2016-04-21 2019-09-17 Optimus Drugs Private Limited Process for the preparation of linezolid
AU2016403208B2 (en) * 2016-04-21 2018-10-25 Optimus Drugs Pvt Ltd An improved process for the preparation of Linezolid
EP3452484B1 (de) 2016-05-07 2023-07-05 Fochon Pharmaceuticals, Ltd. Bestimmte proteinkinasehemmer
EP3544965A4 (de) 2016-11-28 2020-05-20 Shanghai Fochon Pharmaceutical Co., Ltd. Sulfoximin-, sulfonimidamid-, sulfondiimin- und diimidosulfonamidverbindungen als inhibitoren von indolamin-2,3-dioxygenase
EP3601255A1 (de) 2017-03-21 2020-02-05 AbbVie Deutschland GmbH & Co. KG Prolinamidverbindungen und deren azetidinanaloga, diespezifisch substituiertes benzylradikal tragen
ES2927182T3 (es) 2017-04-18 2022-11-03 Shanghai Fochon Pharmaceutical Co Ltd Agentes inductores de la apoptosis
KR20200141035A (ko) 2018-03-14 2020-12-17 포천 파마슈티컬즈, 엘티디. TRK 키나제 억제제로서의 치환된 (2-아자비사이클로 [3.1.0] 헥산-2-일) 피라졸로 [1, 5-a] 피리미딘 및 이미다조 [1, 2-b] 피리다진 화합물
CN112771025B (zh) 2018-03-23 2024-02-27 重庆复创医药研究有限公司 作为rock抑制剂的氘代化合物
CN109232457A (zh) * 2018-03-26 2019-01-18 华夏生生药业(北京)有限公司 一种利奈唑胺的制备方法
CN108892663A (zh) * 2018-08-10 2018-11-27 泰州申合泰尔生物医药有限公司 一种合成利伐沙班的中间体、合成方法和用途
CN113045509B (zh) * 2021-06-01 2021-10-22 上海翰森生物医药科技有限公司 利奈唑胺的工业生产方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2810349A1 (de) 1978-03-10 1979-09-20 Kali Chemie Pharma Gmbh Verfahren zur herstellung von 3-hydroxy-6-phenyl-1,2,3,4-tetrahydro- 1,5-benzodiazocinen
FR2506769A2 (fr) 1978-06-09 1982-12-03 Delalande Sa Para-((cyano-5 n pentyl-1) phenyl)-3 methoxymethyl-5 oxazolidinone-2, son procede de preparation et ses applications en therapeutique
US4340606A (en) * 1980-10-23 1982-07-20 E. I. Du Pont De Nemours And Company 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents
FR2608604B1 (fr) 1986-12-19 1989-04-28 Delalande Sa Derives 5-hydroxyethyles de l'oxazolidinone-2, leurs procedes de preparation et leurs applications en therapeutique
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
US5688792A (en) 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
HUP0500044A3 (en) * 1996-04-11 2005-09-28 Upjohn Co Process for prepare oxazolidinones
KR100619639B1 (ko) 1997-11-07 2006-09-06 파마시아 앤드 업존 캄파니 엘엘씨 옥사졸리디논의 제조 방법
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
DE10105989A1 (de) * 2001-02-09 2002-08-14 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
CN1155585C (zh) 2001-12-19 2004-06-30 中国医学科学院医药生物技术研究所 3,5－取代噁唑烷酮衍生物及其制备方法和应用
ES2294494T3 (es) * 2004-04-19 2008-04-01 Symed Labs Limited Un nuevo procedimiento para la preparacion de linezolid y compuestos relacionados.

Also Published As

Publication number Publication date
DE602004020812D1 (de) 2009-06-04
WO2006008754A1 (en) 2006-01-26
EP1768967A1 (de) 2007-04-04
EP1768967B1 (de) 2009-04-22
US20060247435A1 (en) 2006-11-02
PL1768967T3 (pl) 2009-09-30
US7429661B2 (en) 2008-09-30
ES2325401T3 (es) 2009-09-03

Similar Documents

Publication Publication Date Title
ATE429423T1 (de) Neue zwischenprodukte für linezolid und verwandte verbindungen
WO2005099353A3 (en) A novel process for the preparation of linezolid and related compounds
Cole Recent stereoselective synthetic approaches to β-amino acids
AU2010242496B2 (en) Processes for the preparation of Rivaroxaban and intermediates thereof
Stecko et al. Kinugasa reaction: an ‘ugly duckling’of β-lactam chemistry
PE20091974A1 (es) Derivados de indazoles sustituidos con fenil o piridinilo
ZA200603942B (en) Derivatives of N-[phenyl(alkylpiperidine-2-yl)methyl]benzamide, preparation method thereof and application of same in therapeutics
CA2434937A1 (en) Phenyl derivatives
GB0315966D0 (en) Compounds
SI2824100T1 (en) 1,2,5-oxadiazoles as inhibitors of indolamine 2,3-dioxygenase
CZ20031799A3 (cs) Nové heterocyklické sloučeniny s antibakteriálním účinkem, způsob jejich výroby a farmaceutické kompozice s jejich obsahem
AR038915A1 (es) Derivados de aminoindazoles, procedimiento de preparacion e intermedios de este procedimiento, medicamentos y composiciones farmaceuticas que contienen al compuesto
AR054417A1 (es) Derivados de imidazol. proceso de obtencion y composiciones farmaceuticas.
KR20070027614A (ko) 항박테리아제로서의3-[4-(6-｛4,5-디히드로이속사졸-3-일｝피리딘-3-일)-3-페닐]-5-(1ｈ-1,2,3-트리아졸-1-일메틸)-1,3-옥사졸리딘-2-온
WO2012114355A1 (en) Novel process for preparation of linezolid and its novel intermediates
HUP0400491A2 (hu) Eljárás (2R,2-alfa-R,3A)-2-[1-[3,5-bisz(trifluormetil)fenil]-etoxi-3-(4-fluorfenil)-1,4-oxazin előállítására
Carroccia et al. Straightforward access to 4-membered sulfurated heterocycles: introducing a strategy for the single and double functionalization of thietane 1-oxide
He et al. Synthesis of Oxazolidin‐2‐ones and Imidazolidin‐2‐ones Directly from 1, 3‐Diols or 3‐Amino Alcohols using Iodobenzene Dichloride and Sodium Azide
Bhattarai et al. Synthesis and in vitro evaluation of the antitubercular and antibacterial activity of novel oxazolidinones bearing octahydrocyclopenta [c] pyrrol-2-yl moieties
GEP20063896B (en) New heterocyclic oxime compound, method for production of the same and pharmaceutical composition comprising the same
CA2449578A1 (en) Pyrrolidine oxadiazole- and thiadiazole derivatives
EP2072505A3 (de) Verfahren zur Herstellung von Oxazolidinonderivaten
Sugiyama et al. Enantioselective addition of diethylzinc to aldehydes catalyzed by monosubstituted [2.2] paracyclophane-based N, O-ligands: remarkable cooperative effects of planar and central chiralities
CN1136810A (zh) 5-芳基异噁唑-4-基-取代的2-氨基羧酸化合物
ATE435204T1 (de) 3-(((4-phenyl)-piperazin-1-yl)-alkyl)-3-alkyl-1 3-dihydro-2h-indol-2-on-derivate und verwandte verbindungen zur behandlung von erkrankungen des zentralnervensystems

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties