ATE413192T1 - Die vorbeugung und behandlung von netzhautischämie und ödem - Google Patents
Die vorbeugung und behandlung von netzhautischämie und ödemInfo
- Publication number
- ATE413192T1 ATE413192T1 AT99967762T AT99967762T ATE413192T1 AT E413192 T1 ATE413192 T1 AT E413192T1 AT 99967762 T AT99967762 T AT 99967762T AT 99967762 T AT99967762 T AT 99967762T AT E413192 T1 ATE413192 T1 AT E413192T1
- Authority
- AT
- Austria
- Prior art keywords
- antagonist
- edema
- prevention
- treatment
- retinal ischemia
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Computer And Data Communications (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11422198P | 1998-12-30 | 1998-12-30 | |
US09/248,752 US6670321B1 (en) | 1998-12-30 | 1999-02-12 | Prevention and treatment for retinal ischemia and edema |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE413192T1 true ATE413192T1 (de) | 2008-11-15 |
Family
ID=26811943
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99967762T ATE413192T1 (de) | 1998-12-30 | 1999-12-29 | Die vorbeugung und behandlung von netzhautischämie und ödem |
Country Status (7)
Country | Link |
---|---|
US (5) | US6670321B1 (de) |
EP (1) | EP1140172B1 (de) |
AT (1) | ATE413192T1 (de) |
AU (1) | AU761646B2 (de) |
CA (1) | CA2357873A1 (de) |
DE (1) | DE69939878D1 (de) |
WO (1) | WO2000038714A1 (de) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020155511A1 (en) * | 2000-09-08 | 2002-10-24 | Carolyn Horrocks | Novel antibody compositions for the negative selection of specific rat leukocyte subsets |
AU2002223649A1 (en) * | 2000-10-27 | 2002-05-06 | Novartis Ag | Vegh inhibitors and their use |
EP1534751B1 (de) * | 2002-08-28 | 2010-04-14 | Novartis AG | Gentherapie des auges |
PT1682537E (pt) * | 2003-11-05 | 2012-06-20 | Sarcode Bioscience Inc | Moduladores de adesão celular |
US7731360B2 (en) * | 2003-11-07 | 2010-06-08 | Neuro Kinetics | Portable video oculography system |
US7419666B1 (en) | 2004-02-23 | 2008-09-02 | Massachusetts Eye And Ear Infirmary | Treatment of ocular disorders |
US20080299130A1 (en) * | 2004-05-04 | 2008-12-04 | University Of Kentucky Research Foundation | Methods And Compositions For The Treatment Of Ocular Neovascularization |
PL2444079T3 (pl) | 2005-05-17 | 2017-07-31 | Sarcode Bioscience Inc. | Kompozycje i sposoby leczenia chorób oczu |
US8367629B2 (en) * | 2006-02-14 | 2013-02-05 | Noxxon Pharma Ag | MCP-1 binding nucleic acids and use thereof |
RU2518330C2 (ru) * | 2006-02-14 | 2014-06-10 | Ноксон Фарма Аг | Нуклеиновые кислоты, связывающиеся с мср-1 |
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
US8267905B2 (en) * | 2006-05-01 | 2012-09-18 | Neurosystec Corporation | Apparatus and method for delivery of therapeutic and other types of agents |
US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
WO2007131050A2 (en) * | 2006-05-02 | 2007-11-15 | Georgia Tech Research Corporation | Method for drug delivery to ocular tissue using microneedle |
US7803148B2 (en) | 2006-06-09 | 2010-09-28 | Neurosystec Corporation | Flow-induced delivery from a drug mass |
JP2010511595A (ja) * | 2006-07-31 | 2010-04-15 | ニューロシステック コーポレイション | 遊離塩基ガシクリジンナノ粒子 |
US7553486B2 (en) * | 2006-11-13 | 2009-06-30 | Paul Theodore Finger | Anti-VEGF treatment for radiation-induced vasculopathy |
WO2008103301A2 (en) * | 2007-02-16 | 2008-08-28 | President And Fellows Of Harvard College | Treatment of the eye using macrophages and/or agents able to affect blood vessel morphology |
EP2167956A4 (de) * | 2007-05-02 | 2010-07-14 | Agency Science Tech & Res | Verfahren zur retinopathie-überwachung |
CA2702984C (en) | 2007-10-19 | 2017-04-11 | Sarcode Corporation | Compositions and methods for treatment of diabetic retinopathy |
US20090170770A1 (en) * | 2007-11-06 | 2009-07-02 | Ali Hafezi-Moghadam | Methods and compositions for treating conditions associated with angiogenesis using a vascular adhesion protein-1 (vap 1) inhibitor |
AU2008329070B2 (en) * | 2007-11-30 | 2014-11-20 | Noxxon Pharma Ag | MCP-I binding nucleic acids and use thereof |
US9655515B2 (en) * | 2008-04-08 | 2017-05-23 | Neuro Kinetics | Method of precision eye-tracking through use of iris edge based landmarks in eye geometry |
WO2009128932A1 (en) * | 2008-04-15 | 2009-10-22 | Sarcode Corporation | Delivery of lfa-1 antagonists to the gastrointestinal system |
WO2009139817A2 (en) | 2008-04-15 | 2009-11-19 | Sarcode Corporation | Crystalline pharmaceutical and methods of preparation and use thereof |
EP3632444A3 (de) | 2008-04-15 | 2020-08-26 | SARcode Bioscience Inc. | Topische lfa-1-antagonisten zur verwendung in der lokalen behandlung von immunerkrankungen |
EP2265124A4 (de) * | 2008-04-15 | 2011-12-28 | Sarcode Bioscience Inc | Aerosolisierte lfa-1-antagonisten zur verwendung bei der lokalen behandlung von immunerkrankungen |
US10398309B2 (en) | 2008-10-09 | 2019-09-03 | Neuro Kinetics, Inc. | Noninvasive rapid screening of mild traumatic brain injury using combination of subject's objective oculomotor, vestibular and reaction time analytic variables |
US9039631B2 (en) | 2008-10-09 | 2015-05-26 | Neuro Kinetics | Quantitative, non-invasive, clinical diagnosis of traumatic brain injury using VOG device for neurologic testing |
US8585609B2 (en) * | 2008-10-09 | 2013-11-19 | Neuro Kinetics, Inc. | Quantitative, non-invasive, clinical diagnosis of traumatic brain injury using simulated distance visual stimulus device for neurologic testing |
WO2010048365A2 (en) * | 2008-10-23 | 2010-04-29 | Arizona Technology Enterprises | Therapeutic peptide bioconjugates |
WO2010054393A1 (en) * | 2008-11-10 | 2010-05-14 | Mount Sinai School Of Medicine Of New York University | Methods of inhibiting inflammation-associated tissue damage by inhibiting neutrophil activity |
JP5871792B2 (ja) | 2009-04-27 | 2016-03-01 | アボット・ラボラトリーズAbbott Laboratories | 自動血液分析器において、レーザーからの前方散乱を用いることによる、赤血球細胞を白血球細胞から判別する方法 |
US8389474B1 (en) * | 2009-07-14 | 2013-03-05 | Alan Anson Wanderer | Rationale for IL-1 β targeted therapy to improve harvested organ viability, allograft tolerance, replant success and for conditions characterized by reduced or absent arterial perfusion |
US8378105B2 (en) * | 2009-10-21 | 2013-02-19 | Sarcode Bioscience Inc. | Crystalline pharmaceutical and methods of preparation and use thereof |
WO2011065968A1 (en) * | 2009-11-30 | 2011-06-03 | The Scripps Research Institute | Use of monocyte chemoattractant compounds to treat ocular disorders |
EP2627292B1 (de) | 2010-10-15 | 2018-10-10 | Clearside Biomedical, Inc. | Vorrichtung für okularen zugang |
US9705124B2 (en) | 2012-02-27 | 2017-07-11 | The Johns Hopkins University | High energy density Li-ion battery electrode materials and cells |
CN110922393A (zh) | 2012-07-25 | 2020-03-27 | 诺华股份有限公司 | Lfa-1抑制剂及其多晶型物 |
US8808179B1 (en) | 2012-08-06 | 2014-08-19 | James Z. Cinberg | Method and associated apparatus for detecting minor traumatic brain injury |
EP2887982B1 (de) | 2012-08-27 | 2022-11-23 | Clearside Biomedical, Inc. | Vorrichtung zur arzneimittelverabreichung mit mikronadeln |
BR112015010566A2 (pt) | 2012-11-08 | 2017-07-11 | Clearside Biomedical Inc | métodos e dispositivos para o tratamento de doenças oculares em indivíduos humanos |
CA3121759C (en) | 2013-05-03 | 2024-01-02 | Clearside Biomedical, Inc. | Apparatus and methods for ocular injection |
WO2014197317A1 (en) | 2013-06-03 | 2014-12-11 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
CA2933900A1 (en) | 2013-12-20 | 2015-06-25 | Georgia Tech Research Corporation | Formulations and methods for targeted ocular delivery of therapeutic agents |
WO2015196085A2 (en) | 2014-06-20 | 2015-12-23 | Clearside Biomedical, Inc. | Variable diameter cannula and methods for controlling insertion depth for medicament delivery |
USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
WO2017109164A1 (en) * | 2015-12-23 | 2017-06-29 | Université Pierre Et Marie Curie - Paris 6 (Upmc) | AGENTS THAT INHIBIT THE BINDING OF CFH TO CD11b/CD18 AND USES THEREOF |
US10390901B2 (en) | 2016-02-10 | 2019-08-27 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
EP3452165A1 (de) | 2016-05-02 | 2019-03-13 | Clearside Biomedical, Inc. | Systeme und verfahren zur verabreichung eines augenmedikaments |
WO2017201165A1 (en) | 2016-05-17 | 2017-11-23 | Genecentric Diagnostics, Inc. | Methods for subtyping of lung adenocarcinoma |
US11041214B2 (en) | 2016-05-17 | 2021-06-22 | Genecentric Therapeutics, Inc. | Methods for subtyping of lung squamous cell carcinoma |
EP3496680B1 (de) | 2016-08-12 | 2024-10-02 | Clearside Biomedical, Inc. | Vorrichtung zur einstellung der einsatztiefe einer kanüle zur medikamentenabgabe |
WO2018204515A1 (en) | 2017-05-02 | 2018-11-08 | Georgia Tech Research Corporation | Targeted drug delivery methods using a microneedle |
WO2019032525A1 (en) | 2017-08-07 | 2019-02-14 | Genecentric Therapeutics, Inc. | PROCESS FOR SUBTYPING EPIDERMOID CARCINOMA OF HEAD AND NECK |
CA3115922A1 (en) | 2018-10-09 | 2020-04-16 | Genecentric Therapeutics, Inc. | Detecting cancer cell of origin |
EP4093508A1 (de) | 2020-01-24 | 2022-11-30 | Pfizer Inc. | Anti-e-selectin-antikörper, zusammensetzungen und verwendungsverfahren |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5284931A (en) | 1987-05-04 | 1994-02-08 | Dana Farber Cancer Institute | Intercellular adhesion molecules, and their binding ligands |
EP0314863B1 (de) | 1987-11-02 | 1994-12-07 | Baylor College Of Medicine | Verwendung von ICAM-1 oder ihre funktionelle Derivate zur Behandlung unspezifischer Entzündungen |
CA2008368C (en) | 1989-01-24 | 2003-04-08 | Jeffrey Greve | Soluble molecule related to but distinct from icam-1 |
GB9009549D0 (en) | 1990-04-27 | 1990-06-20 | Celltech Ltd | Recombinant antibody and method |
GB9009548D0 (en) | 1990-04-27 | 1990-06-20 | Celltech Ltd | Chimeric antibody and method |
US5223396A (en) | 1991-05-03 | 1993-06-29 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for detecting organ transplant rejection |
JPH07502727A (ja) | 1991-10-01 | 1995-03-23 | ザ・ジエネラル・ホスピタル・コーポレーシヨン | 接着分子に対する抗体を用いた同種移植片拒絶の防止 |
ATE180408T1 (de) | 1991-10-04 | 1999-06-15 | Us Health | Herstellung eines arzneimittels zur behandlung von augenentzündung durch blockierung von zelladhäsionsmolekulen |
US5831029A (en) * | 1993-12-23 | 1998-11-03 | Icos Corporation | Human β2 integrin α subunit |
JPH08332181A (ja) * | 1995-06-09 | 1996-12-17 | Kdk Corp | 生体の位置決め方法および生体情報測定用位置決め装置並びに生体情報測定装置 |
US5730977A (en) * | 1995-08-21 | 1998-03-24 | Mitsui Toatsu Chemicals, Inc. | Anti-VEGF human monoclonal antibody |
JP2000511541A (ja) * | 1996-05-30 | 2000-09-05 | ユニバーシティー オブ ブリティッシュ コロンビア | リポソームアンチセンス送達の効果の増強 |
US5814500A (en) | 1996-10-31 | 1998-09-29 | The Johns Hopkins University School Of Medicine | Delivery construct for antisense nucleic acids and methods of use |
CA2273203A1 (en) | 1996-12-02 | 1998-06-11 | Dyad Pharmaceutical Corporation | Antisense inhibition of human adhesion molecules |
DK0973550T3 (da) | 1997-04-11 | 2003-02-10 | Searle & Co | Antagonistiske anti-AVB3-integrin-antistoffer |
EP1806135A3 (de) | 1998-03-13 | 2010-11-24 | The Johns Hopkins University School Of Medicine | Verwendung eines Protein-Tyrosin-Hemmers wie Genistein bei der Behandlung von diabetischer Retinopathie und Augenentzündungen |
ATE330631T1 (de) * | 1999-01-05 | 2006-07-15 | Univ Southern Australia | Antikörperfragmente zur lokalen behandlung von augenerkrankungen |
-
1999
- 1999-02-12 US US09/248,752 patent/US6670321B1/en not_active Expired - Fee Related
- 1999-12-29 WO PCT/US1999/031215 patent/WO2000038714A1/en active IP Right Grant
- 1999-12-29 AU AU23985/00A patent/AU761646B2/en not_active Ceased
- 1999-12-29 DE DE69939878T patent/DE69939878D1/de not_active Expired - Lifetime
- 1999-12-29 AT AT99967762T patent/ATE413192T1/de not_active IP Right Cessation
- 1999-12-29 CA CA002357873A patent/CA2357873A1/en not_active Abandoned
- 1999-12-29 EP EP99967762A patent/EP1140172B1/de not_active Expired - Lifetime
- 1999-12-29 US US09/474,523 patent/US6524581B1/en not_active Expired - Fee Related
-
2003
- 2003-02-11 US US10/364,922 patent/US20040028648A1/en not_active Abandoned
-
2007
- 2007-01-09 US US11/651,334 patent/US20080019977A1/en not_active Abandoned
-
2010
- 2010-01-08 US US12/684,215 patent/US20100203061A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2398500A (en) | 2000-07-31 |
EP1140172A1 (de) | 2001-10-10 |
US20100203061A1 (en) | 2010-08-12 |
WO2000038714A8 (en) | 2000-08-03 |
US6524581B1 (en) | 2003-02-25 |
CA2357873A1 (en) | 2000-07-06 |
EP1140172B1 (de) | 2008-11-05 |
US20080019977A1 (en) | 2008-01-24 |
US6670321B1 (en) | 2003-12-30 |
AU761646B2 (en) | 2003-06-05 |
WO2000038714A1 (en) | 2000-07-06 |
US20040028648A1 (en) | 2004-02-12 |
DE69939878D1 (de) | 2008-12-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |