ATE408141T1 - Gen-detektionschip, sensor und nachweisverfahren - Google Patents
Gen-detektionschip, sensor und nachweisverfahrenInfo
- Publication number
- ATE408141T1 ATE408141T1 AT00969958T AT00969958T ATE408141T1 AT E408141 T1 ATE408141 T1 AT E408141T1 AT 00969958 T AT00969958 T AT 00969958T AT 00969958 T AT00969958 T AT 00969958T AT E408141 T1 ATE408141 T1 AT E408141T1
- Authority
- AT
- Austria
- Prior art keywords
- pin electrodes
- sensor
- gene
- detection
- recess
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00653—Making arrays on substantially continuous surfaces the compounds being bound to electrodes embedded in or on the solid supports
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Electrochemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP29891799 | 1999-10-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE408141T1 true ATE408141T1 (de) | 2008-09-15 |
Family
ID=17865860
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00969958T ATE408141T1 (de) | 1999-10-20 | 2000-10-20 | Gen-detektionschip, sensor und nachweisverfahren |
Country Status (8)
Country | Link |
---|---|
US (1) | US6916614B1 (de) |
EP (1) | EP1146331B1 (de) |
KR (1) | KR20010099859A (de) |
CN (1) | CN1223851C (de) |
AT (1) | ATE408141T1 (de) |
AU (1) | AU7952700A (de) |
DE (1) | DE60040205D1 (de) |
WO (1) | WO2001029550A1 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002066969A1 (fr) * | 2001-02-19 | 2002-08-29 | Kyowa Medex Co., Ltd. | Detecteur de composant charge, son procede d'utilisation et un panneau de detection |
JP2002372533A (ja) * | 2001-06-13 | 2002-12-26 | Kiwamu Akagi | 血液の検査方法、検査用チップ、並びに検査装置 |
DE10208794A1 (de) * | 2002-02-28 | 2003-09-04 | Degussa Bioactives Gmbh | Verfahren zum Sortieren einsträngiger Nucleinsäuren |
WO2004011646A1 (ja) * | 2002-07-30 | 2004-02-05 | Tum Gene,Inc. | 塩基変異の検出法 |
US7097751B2 (en) | 2002-08-23 | 2006-08-29 | Kabushiki Kaisha Toshiba | Base sequence detecting electrode, base sequence detecting device and base sequence detecting method |
ATE544867T1 (de) * | 2002-12-11 | 2012-02-15 | Centre Nat Rech Scient | Methode zur elektronischen detektion wenigstens einer spezifischen interaktion zwischen einem proben- und einem zielmolekül |
WO2004102194A1 (ja) * | 2003-05-19 | 2004-11-25 | Toray Industries, Inc. | 選択結合性物質固定化担体 |
JP4285119B2 (ja) * | 2003-07-07 | 2009-06-24 | ソニー株式会社 | 生化学反応装置、生化学反応用基板、ハイブリダイゼーション用基板の製造方法及びハイブリダイゼーション方法 |
JP4466074B2 (ja) * | 2003-12-26 | 2010-05-26 | 株式会社日立製作所 | 微細金属構造体とその製造方法、並びに微細金型とデバイス |
KR101050468B1 (ko) * | 2004-02-14 | 2011-07-19 | 삼성에스디아이 주식회사 | 바이오 칩 및 이를 이용한 바이오 분자 검출 시스템 |
JP4872244B2 (ja) * | 2005-06-03 | 2012-02-08 | 横河電機株式会社 | 化学反応用カートリッジ |
JP4353958B2 (ja) * | 2005-09-15 | 2009-10-28 | 株式会社日立製作所 | Dna計測装置、及びdna計測方法 |
CA2682761C (en) | 2007-04-04 | 2015-10-13 | Network Biosystems, Inc. | Methods for rapid multiplexed amplification of target nucleic acids |
US7871571B2 (en) * | 2007-10-25 | 2011-01-18 | Parker John A | Biomolecule analyzing system |
JP2010011791A (ja) * | 2008-07-03 | 2010-01-21 | Toshiba Corp | 複数核酸の検出方法 |
GB0822733D0 (en) * | 2008-12-12 | 2009-01-21 | Univ Warwick | Nanotube electrochemistry |
WO2010147654A2 (en) | 2009-06-15 | 2010-12-23 | Netbio Inc. | Improved methods for forensic dna quantitation |
JP2011232328A (ja) * | 2010-04-09 | 2011-11-17 | Hitachi Ltd | 生体物質検出アレイ、計測装置および計測方法 |
KR101982627B1 (ko) | 2011-05-12 | 2019-05-27 | 에이엔디이 코포레이션 | Str 유전자좌의 신속한 다중 증폭 방법 및 조성법 |
CN104049011B (zh) * | 2014-06-30 | 2016-10-12 | 安徽师范大学 | 一种电化学生物传感器,其制备方法,用途以及检测血小板源生长因子的方法 |
CN106153940A (zh) * | 2014-10-17 | 2016-11-23 | 广州瑞博奥生物科技有限公司 | 一种用于检测血管生成因子的抗体芯片试剂盒 |
CN106153939A (zh) * | 2014-10-17 | 2016-11-23 | 广州瑞博奥生物科技有限公司 | 一种用于检测凋亡因子的抗体芯片试剂盒 |
US10488365B2 (en) * | 2015-06-17 | 2019-11-26 | Qualcomm Incorporated | Current sensors using bipolar transistors |
EP3314245A4 (de) | 2015-06-25 | 2019-02-27 | Roswell Biotechnologies, Inc | Biomolekulare sensoren und verfahren |
CN105296351A (zh) * | 2015-12-02 | 2016-02-03 | 北京大学 | 用于聚合酶链式反应的芯片、实时检测装置和系统 |
US10712334B2 (en) | 2016-01-28 | 2020-07-14 | Roswell Biotechnologies, Inc. | Massively parallel DNA sequencing apparatus |
US11624725B2 (en) | 2016-01-28 | 2023-04-11 | Roswell Blotechnologies, Inc. | Methods and apparatus for measuring analytes using polymerase in large scale molecular electronics sensor arrays |
EP3414784B1 (de) | 2016-02-09 | 2021-04-14 | Roswell Biotechnologies, Inc | Elektronische markierungsfreie dna- und genomsequenzierung |
US10597767B2 (en) | 2016-02-22 | 2020-03-24 | Roswell Biotechnologies, Inc. | Nanoparticle fabrication |
US9829456B1 (en) | 2016-07-26 | 2017-11-28 | Roswell Biotechnologies, Inc. | Method of making a multi-electrode structure usable in molecular sensing devices |
WO2018132457A1 (en) | 2017-01-10 | 2018-07-19 | Roswell Biotechnologies, Inc. | Methods and systems for dna data storage |
WO2018136148A1 (en) | 2017-01-19 | 2018-07-26 | Roswell Biotechnologies, Inc. | Solid state sequencing devices comprising two dimensional layer materials |
CA3057151A1 (en) | 2017-04-25 | 2018-11-01 | Roswell Biotechnologies, Inc. | Enzymatic circuits for molecular sensors |
US10508296B2 (en) | 2017-04-25 | 2019-12-17 | Roswell Biotechnologies, Inc. | Enzymatic circuits for molecular sensors |
EP4023764A3 (de) | 2017-05-09 | 2022-09-21 | Roswell Biotechnologies, Inc. | Bindungssondenschaltungen für molekulare sensoren |
TWI745392B (zh) * | 2017-06-29 | 2021-11-11 | 瑞禾生物科技股份有限公司 | 生物感測元件及其製造方法以及生物分子檢測方法 |
EP3676389A4 (de) | 2017-08-30 | 2021-06-02 | Roswell Biotechnologies, Inc | Prozessive enzymatische molekulare elektronische sensoren zur speicherung von dna-daten |
CN111373051A (zh) | 2017-10-10 | 2020-07-03 | 罗斯威尔生命技术公司 | 用于无扩增dna数据存储的方法、装置和系统 |
CN110227565B (zh) | 2019-06-25 | 2021-03-19 | 京东方科技集团股份有限公司 | 微流控器件及制作方法、生物分子数量检测方法及系统 |
KR20220114030A (ko) * | 2020-01-07 | 2022-08-17 | 엘지전자 주식회사 | 전기장 인가용 커버 및 이를 포함하는 전기장 인가 장치 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS56152958A (en) | 1980-04-30 | 1981-11-26 | Mitsubishi Electric Corp | Electroless gold plating solution |
US4343684A (en) | 1980-12-19 | 1982-08-10 | Stanley Lechtzin | Method of electroforming and product |
EP0149339B1 (de) | 1983-12-16 | 1989-08-23 | MediSense, Inc. | Test für Nukleinsäuren |
US4857831A (en) | 1986-12-29 | 1989-08-15 | Schlumberger Technology Corporation | Borehole casing diagnostic apparatus and method |
US5108576A (en) | 1988-06-13 | 1992-04-28 | Ohmicron Corporation | Pyroelectric thermometric device |
US5776672A (en) * | 1990-09-28 | 1998-07-07 | Kabushiki Kaisha Toshiba | Gene detection method |
US5605662A (en) * | 1993-11-01 | 1997-02-25 | Nanogen, Inc. | Active programmable electronic devices for molecular biological analysis and diagnostics |
US5846708A (en) * | 1991-11-19 | 1998-12-08 | Massachusetts Institiute Of Technology | Optical and electrical methods and apparatus for molecule detection |
GB9201481D0 (en) | 1992-01-23 | 1992-03-11 | Scient Generics Ltd | Treatment of nucleic acid material |
US6071394A (en) | 1996-09-06 | 2000-06-06 | Nanogen, Inc. | Channel-less separation of bioparticles on a bioelectronic chip by dielectrophoresis |
JP3331261B2 (ja) | 1994-08-19 | 2002-10-07 | 日本エレクトロプレイテイング・エンジニヤース株式会社 | 無電解金めっき液 |
EP0821745A1 (de) | 1995-04-17 | 1998-02-04 | The Board Of Trustees Of The University Of Arkansas | Verfahren zum elektrobeschichten von substraten und so hergestellte produkte |
JP3671100B2 (ja) | 1996-02-23 | 2005-07-13 | 日本碍子株式会社 | 酸化物センサ |
JP3764779B2 (ja) | 1996-03-30 | 2006-04-12 | 株式会社東北テクノアーチ | 凸状領域を用いた分析方法 |
JP3233851B2 (ja) | 1996-04-24 | 2001-12-04 | 繁織 竹中 | 遺伝子の電気化学的検出法およびその装置 |
ZA975891B (en) * | 1996-07-05 | 1998-07-23 | Combimatrix Corp | Electrochemical solid phase synthesis of polymers |
IL131486A0 (en) | 1997-02-21 | 2001-01-28 | Burstein Lab Inc | Gene sequencer and methods |
FR2764385B1 (fr) | 1997-06-06 | 1999-07-16 | Commissariat Energie Atomique | Microsysteme d'analyse de liquides a cuvette integree |
US6048692A (en) * | 1997-10-07 | 2000-04-11 | Motorola, Inc. | Sensors for electrically sensing binding events for supported molecular receptors |
US6287776B1 (en) * | 1998-02-02 | 2001-09-11 | Signature Bioscience, Inc. | Method for detecting and classifying nucleic acid hybridization |
DE19841337C1 (de) * | 1998-05-27 | 1999-09-23 | Micronas Intermetall Gmbh | Verfahren und Vorrichtung zur intrazellulären Manipulation einer biologischen Zelle |
US6093370A (en) | 1998-06-11 | 2000-07-25 | Hitachi, Ltd. | Polynucleotide separation method and apparatus therefor |
JP3888807B2 (ja) * | 1999-08-06 | 2007-03-07 | 凸版印刷株式会社 | 遺伝子を検出する方法、並びに検出装置及び検出用チップ |
US6749731B2 (en) | 2001-01-31 | 2004-06-15 | Kyocera Corporation | Gene detection chip and detection device |
-
2000
- 2000-10-20 EP EP00969958A patent/EP1146331B1/de not_active Expired - Lifetime
- 2000-10-20 US US09/868,576 patent/US6916614B1/en not_active Expired - Fee Related
- 2000-10-20 AU AU79527/00A patent/AU7952700A/en not_active Abandoned
- 2000-10-20 KR KR1020017007821A patent/KR20010099859A/ko not_active Application Discontinuation
- 2000-10-20 CN CNB008039984A patent/CN1223851C/zh not_active Expired - Fee Related
- 2000-10-20 WO PCT/JP2000/007342 patent/WO2001029550A1/ja active IP Right Grant
- 2000-10-20 AT AT00969958T patent/ATE408141T1/de not_active IP Right Cessation
- 2000-10-20 DE DE60040205T patent/DE60040205D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU7952700A (en) | 2001-04-30 |
US6916614B1 (en) | 2005-07-12 |
CN1223851C (zh) | 2005-10-19 |
DE60040205D1 (de) | 2008-10-23 |
EP1146331A4 (de) | 2006-08-30 |
WO2001029550A1 (fr) | 2001-04-26 |
EP1146331A1 (de) | 2001-10-17 |
CN1341211A (zh) | 2002-03-20 |
EP1146331B1 (de) | 2008-09-10 |
KR20010099859A (ko) | 2001-11-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |