ATE398110T1 - 3-aminochinazolin-2,4-dione als antibakterielle mittel - Google Patents

3-aminochinazolin-2,4-dione als antibakterielle mittel

Info

Publication number: ATE398110T1
Authority: AT; Austria
Prior art keywords: aminoquinazoline; dione; antibacterial agent; antibacterial; agent
Prior art date: 2000-01-24

Application number

AT00984246T

Other languages

English (en)

Inventor

Paul Bird

Edmund Ellsworth

Dai Nguyen

Joseph SANCHEZ

Howard Showalter

Rajeshwar Singh

Michael STIER

Tuan Tran

Brian Watson

Judy Yip

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-24

Filing date

2000-12-12

Publication date

2008-07-15

2000-12-12 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2008-07-15 Application granted granted Critical

2008-07-15 Publication of ATE398110T1 publication Critical patent/ATE398110T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Paper (AREA)

AT00984246T 2000-01-24 2000-12-12 3-aminochinazolin-2,4-dione als antibakterielle mittel ATE398110T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US17825200P	2000-01-24	2000-01-24
US24126700P	2000-10-18	2000-10-18

Publications (1)

Publication Number	Publication Date
ATE398110T1 true ATE398110T1 (de)	2008-07-15

Family

ID=26874138

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00984246T ATE398110T1 (de)	2000-01-24	2000-12-12	3-aminochinazolin-2,4-dione als antibakterielle mittel

Country Status (38)

Country	Link
US (2)	US7094780B1 (de)
EP (1)	EP1255739B1 (de)
JP (1)	JP4811978B2 (de)
KR (1)	KR20020067701A (de)
CN (1)	CN1425008A (de)
AP (1)	AP2002002603A0 (de)
AR (1)	AR030186A1 (de)
AT (1)	ATE398110T1 (de)
AU (1)	AU783078B2 (de)
BG (1)	BG107023A (de)
BR (1)	BR0017010A (de)
CA (1)	CA2393802C (de)
CO (1)	CO5320600A1 (de)
CR (1)	CR6709A (de)
DE (1)	DE60039194D1 (de)
EA (1)	EA005585B1 (de)
EE (1)	EE200200412A (de)
ES (1)	ES2304992T3 (de)
GE (1)	GEP20053429B (de)
HK (1)	HK1054237A1 (de)
HN (1)	HN2001000009A (de)
HR (1)	HRP20020696A2 (de)
HU (1)	HUP0204101A3 (de)
IL (1)	IL150393A0 (de)
IS (1)	IS6448A (de)
MA (1)	MA26866A1 (de)
MX (1)	MXPA02005989A (de)
NO (1)	NO20023516L (de)
OA (1)	OA12316A (de)
PA (1)	PA8510101A1 (de)
PE (1)	PE20011060A1 (de)
PL (1)	PL356837A1 (de)
SK (1)	SK10572002A3 (de)
SV (1)	SV2001000288A (de)
TN (1)	TNSN01011A1 (de)
UY (1)	UY26551A1 (de)
WO (1)	WO2001053273A1 (de)
YU (1)	YU55902A (de)

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RU2193558C2 (ru)	1997-09-15	2002-11-27	Дзе Проктер Энд Гэмбл Компани	Производные хинолона и фармацевтическая композиция на их основе
BR0210099A (pt)	2001-05-30	2004-04-13	Warner Lambert Co	Agentes antibacterianos
EP1401830A2 (de) *	2001-06-19	2004-03-31	Warner-Lambert Company LLC	Chinazolindione als antibakterielle mittel
US6900224B2 (en) *	2002-07-31	2005-05-31	The Procter & Gamble Company	Antimicrobial quinolones, their compositions and uses
BRPI0414319A (pt) *	2003-09-12	2006-11-07	Warner Lambert Co	agentes antibacterianos de quinolona
WO2005026153A1 (en) *	2003-09-12	2005-03-24	Warner-Lambert Company Llc	Quinazoline-2, 4-diones as antibacterial agents
WO2005049605A1 (en) *	2003-11-18	2005-06-02	Warner-Lambert Company Llc	Antibacterial aminoquinazolidinedione derivatives
WO2006019965A2 (en) *	2004-07-16	2006-02-23	Takeda San Diego, Inc.	Dipeptidyl peptidase inhibitors
GB0416730D0 (en)	2004-07-27	2004-09-01	Novartis Ag	Organic compounds
WO2006079467A1 (en) *	2005-01-26	2006-08-03	F. Hofmann-La Roche Ag	Phenyl methanone derivatives and their use as glycine transporter 1 inhibitors
GB0507298D0 (en)	2005-04-11	2005-05-18	Novartis Ag	Organic compounds
US7977346B2 (en)	2006-01-17	2011-07-12	Guoqing Paul Chen	Spiro compounds and methods of use
JP2009531418A (ja)	2006-03-28	2009-09-03	ザプロクターアンドギャンブルカンパニー	キノロン中間体調製のためのカップリング方法
ATE507219T1 (de)	2006-03-28	2011-05-15	Warner Chilcott Co Llc	Malatsalze und polymorphe von (3s,5s)-7-ä3-amino- 5-methyl-piperidinylü-1-cyclopropyl-1,4-dihydro 8-methoxy-4-oxo-3-chinolincarbonsäure
US20080139574A1 (en)	2006-11-30	2008-06-12	Cadila Healthcare Limited	Novel quinoline derivatives
AU2009209811B2 (en) *	2008-01-30	2011-07-21	Shin Poong Pharmaceutical Co., Ltd.	Novel quinazoline-2,4-dione derivative, and medical compositions for the prophylaxis and treatment of cranial nerve disease containing the same
WO2011031745A1 (en)	2009-09-09	2011-03-17	Achaogen, Inc.	Antibacterial fluoroquinolone analogs
WO2012088266A2 (en)	2010-12-22	2012-06-28	Incyte Corporation	Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
TWI527818B (zh)	2011-03-15	2016-04-01	特留斯治療學有限公司	三環旋轉酶抑制劑
LT2796460T (lt) *	2011-12-21	2018-10-10	Jiangsu Hengrui Medicine Co. Ltd.	Pirolo šešianario heteroarilo žiedo darinys, jo gavimo būdas ir jo medicininis panaudojimas
AR091424A1 (es)	2012-06-13	2015-02-04	Incyte Corp	Compuestos triciclicos sustituidos como inhibidores de receptores del factor de crecimiento del fibroplasto (fgfr)
WO2014026125A1 (en)	2012-08-10	2014-02-13	Incyte Corporation	Pyrazine derivatives as fgfr inhibitors
WO2014043272A1 (en)	2012-09-12	2014-03-20	Trius Therapeutics Inc.	Tricyclic gyrase inhibitors for use as antibacterial agents
US9266892B2 (en)	2012-12-19	2016-02-23	Incyte Holdings Corporation	Fused pyrazoles as FGFR inhibitors
MY181497A (en)	2013-04-19	2020-12-23	Incyte Holdings Corp	Bicyclic heterocycles as fgfr inhibitors
US10851105B2 (en)	2014-10-22	2020-12-01	Incyte Corporation	Bicyclic heterocycles as FGFR4 inhibitors
WO2016134294A1 (en)	2015-02-20	2016-08-25	Incyte Corporation	Bicyclic heterocycles as fgfr4 inhibitors
MA41551A (fr)	2015-02-20	2017-12-26	Incyte Corp	Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
EP3259269B9 (de)	2015-02-20	2020-03-04	Incyte Corporation	Bizyklische heterozyklen als fgfr inhibitoren
CN108530448A (zh) *	2017-03-02	2018-09-14	浙江司太立制药股份有限公司	含有碱性氮杂螺环片段的苯并噻嗪-4-酮类化合物及其制备方法
AR111960A1 (es)	2017-05-26	2019-09-04	Incyte Corp	Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
AU2019262579B2 (en)	2018-05-04	2024-09-12	Incyte Corporation	Salts of an FGFR inhibitor
DK3788047T3 (da)	2018-05-04	2024-09-16	Incyte Corp	Faste former af en FGFR-inhibitor og fremgangsmåder til fremstilling deraf
CN111620866A (zh) *	2019-02-27	2020-09-04	南京药石科技股份有限公司	一种顺式-7,7-二氟-六氢-1H 吡咯并[3,4-c]吡啶衍生物及其制备方法
US11628162B2 (en)	2019-03-08	2023-04-18	Incyte Corporation	Methods of treating cancer with an FGFR inhibitor
WO2021007269A1 (en)	2019-07-09	2021-01-14	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
WO2021067374A1 (en)	2019-10-01	2021-04-08	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
JP2022552324A (ja)	2019-10-14	2022-12-15	インサイト・コーポレイション	Ｆｇｆｒ阻害剤としての二環式複素環
WO2021076728A1 (en)	2019-10-16	2021-04-22	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
US11897891B2 (en)	2019-12-04	2024-02-13	Incyte Corporation	Tricyclic heterocycles as FGFR inhibitors
BR112022010664A2 (pt)	2019-12-04	2022-08-16	Incyte Corp	Derivados de um inibidor de fgfr
WO2021146424A1 (en)	2020-01-15	2021-07-22	Incyte Corporation	Bicyclic heterocycles as fgfr inhibitors
CN111499513B (zh) *	2020-04-24	2023-03-14	上海毕得医药科技股份有限公司	一种2,3,4,5-四溴苯甲酸酯的合成方法
TW202304459A (zh)	2021-04-12	2023-02-01	美商英塞特公司	包含ｆｇｆｒ抑制劑及ｎｅｃｔｉｎ－４靶向劑之組合療法
EP4352059A1 (de)	2021-06-09	2024-04-17	Incyte Corporation	Tricyclische heterocyclen als fgfr-inhibitoren

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DE1068263B (de) *		1959-11-05
FR1203542A (fr) *	1958-02-25	1960-01-19	Rhone Poulenc Sa	Nouveaux dérivés de la phénothiazine comportant en position 10 une chaîne pipérazinique et leurs procédés de préparation
EP0035619B1 (de) *	1980-03-10	1984-07-25	BERRI-BALZAC Société dite:	3-Amino-(1H,3H)-2,4-chinazolindionderivate
GB2097784A (en) *	1981-04-28	1982-11-10	Davidson Dr John Stirton	Dihydrobenzotriazepine diones; aminoquinazoline diones
WO1994014809A1 (de)	1992-12-23	1994-07-07	Byk Gulden Lomberg Chemische Fabrik Gmbh	Anellierte uracilderivate
WO1998018781A2 (en)	1996-10-28	1998-05-07	Versicor, Inc.	Fused 2,4-pyrimidinedione combinatorial libraries, their preparation and the use of fused 2,4-pyrimidinediones derivatives as antimicrobial agents
AU9503998A (en) *	1997-10-28	1999-05-17	Warner-Lambert Company	Novel 7-substituted quinazolin-2,4-diones useful as antibacterial agents
HUP0102514A3 (en)	1998-05-26	2002-03-28	Warner Lambert Co	Pyrido-pyrimidin and pyrimido-pyrimidin derivatives as inhibitors of cellular proliferation and pharmaceutical compositions thereof
ATE305003T1 (de) *	1998-12-11	2005-10-15	Hoffmann La Roche	Zyklische hydrazinderivate als tnf-alpha inhibitoren

2000
- 2000-12-12 AT AT00984246T patent/ATE398110T1/de not_active IP Right Cessation
- 2000-12-12 PL PL00356837A patent/PL356837A1/xx not_active Application Discontinuation
- 2000-12-12 HU HU0204101A patent/HUP0204101A3/hu unknown
- 2000-12-12 EA EA200200661A patent/EA005585B1/ru not_active IP Right Cessation
- 2000-12-12 EE EEP200200412A patent/EE200200412A/xx unknown
- 2000-12-12 US US10/182,221 patent/US7094780B1/en not_active Expired - Fee Related
- 2000-12-12 MX MXPA02005989A patent/MXPA02005989A/es active IP Right Grant
- 2000-12-12 SK SK1057-2002A patent/SK10572002A3/sk unknown
- 2000-12-12 CA CA2393802A patent/CA2393802C/en not_active Expired - Fee Related
- 2000-12-12 YU YU55902A patent/YU55902A/sh unknown
- 2000-12-12 AU AU20899/01A patent/AU783078B2/en not_active Ceased
- 2000-12-12 WO PCT/US2000/033656 patent/WO2001053273A1/en active Search and Examination
- 2000-12-12 OA OA1200200210A patent/OA12316A/en unknown
- 2000-12-12 DE DE60039194T patent/DE60039194D1/de not_active Expired - Lifetime
- 2000-12-12 AP APAP/P/2002/002603A patent/AP2002002603A0/en unknown
- 2000-12-12 JP JP2001553275A patent/JP4811978B2/ja not_active Expired - Fee Related
- 2000-12-12 BR BR0017010-0A patent/BR0017010A/pt not_active Application Discontinuation
- 2000-12-12 CN CN00818578A patent/CN1425008A/zh active Pending
- 2000-12-12 IL IL15039300A patent/IL150393A0/xx unknown
- 2000-12-12 KR KR1020027009515A patent/KR20020067701A/ko not_active Application Discontinuation
- 2000-12-12 ES ES00984246T patent/ES2304992T3/es not_active Expired - Lifetime
- 2000-12-12 GE GE4912A patent/GEP20053429B/en unknown
- 2000-12-12 EP EP00984246A patent/EP1255739B1/de not_active Expired - Lifetime
2001
- 2001-01-19 PA PA20018510101A patent/PA8510101A1/es unknown
- 2001-01-22 TN TNTNSN01011A patent/TNSN01011A1/en unknown
- 2001-01-22 PE PE2001000066A patent/PE20011060A1/es not_active Application Discontinuation
- 2001-01-22 UY UY26551A patent/UY26551A1/es not_active Application Discontinuation
- 2001-01-22 CO CO01004183A patent/CO5320600A1/es not_active Application Discontinuation
- 2001-01-22 SV SV2001000288A patent/SV2001000288A/es not_active Application Discontinuation
- 2001-01-22 HN HN2001000009A patent/HN2001000009A/es unknown
- 2001-01-23 AR ARP010100278A patent/AR030186A1/es unknown
2002
- 2002-06-27 IS IS6448A patent/IS6448A/is unknown
- 2002-07-19 CR CR6709A patent/CR6709A/es not_active Application Discontinuation
- 2002-07-22 MA MA26734A patent/MA26866A1/fr unknown
- 2002-07-23 NO NO20023516A patent/NO20023516L/no not_active Application Discontinuation
- 2002-08-22 BG BG107023A patent/BG107023A/xx unknown
- 2002-08-23 HR HR20020696A patent/HRP20020696A2/hr not_active Application Discontinuation
2003
- 2003-09-11 HK HK03106519.6A patent/HK1054237A1/zh unknown
2006
- 2006-06-13 US US11/452,121 patent/US7582627B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HN2001000009A (es)	2001-06-13
AU783078B2 (en)	2005-09-22
EP1255739B1 (de)	2008-06-11
EP1255739A1 (de)	2002-11-13
BG107023A (en)	2003-04-30
AR030186A1 (es)	2003-08-13
WO2001053273A1 (en)	2001-07-26
CA2393802A1 (en)	2001-07-26
AP2002002603A0 (en)	2002-09-30
US7094780B1 (en)	2006-08-22
MXPA02005989A (es)	2002-10-23
SK10572002A3 (sk)	2003-10-07
US20060287308A1 (en)	2006-12-21
CR6709A (es)	2003-11-25
CO5320600A1 (es)	2003-09-30
HUP0204101A2 (hu)	2003-04-28
CA2393802C (en)	2011-04-19
GEP20053429B (en)	2005-01-25
YU55902A (sh)	2006-01-16
EE200200412A (et)	2003-10-15
SV2001000288A (es)	2001-11-30
HRP20020696A2 (en)	2003-12-31
DE60039194D1 (de)	2008-07-24
JP4811978B2 (ja)	2011-11-09
MA26866A1 (fr)	2004-12-20
IL150393A0 (en)	2002-12-01
AU2089901A (en)	2001-07-31
BR0017010A (pt)	2002-11-05
NO20023516D0 (no)	2002-07-23
CN1425008A (zh)	2003-06-18
ES2304992T3 (es)	2008-11-01
US20060183762A1 (en)	2006-08-17
PL356837A1 (en)	2004-07-12
US7582627B2 (en)	2009-09-01
PE20011060A1 (es)	2001-10-12
UY26551A1 (es)	2001-04-30
PA8510101A1 (es)	2003-06-30
NO20023516L (no)	2002-07-23
HUP0204101A3 (en)	2004-05-28
OA12316A (en)	2006-05-15
EA200200661A1 (ru)	2003-02-27
EA005585B1 (ru)	2005-04-28
HK1054237A1 (zh)	2003-11-21
IS6448A (is)	2002-06-27
JP2003520277A (ja)	2003-07-02
KR20020067701A (ko)	2002-08-23
TNSN01011A1 (en)	2005-11-10

Publication	Publication Date	Title
ATE398110T1 (de)	2008-07-15	3-aminochinazolin-2,4-dione als antibakterielle mittel
DE60134094D1 (de)	2008-07-03	C7-taxanester als antitumormittel
BR0214664B1 (pt)	2012-06-26	peça de vestuário absorvente.
ATE391531T1 (de)	2008-04-15	Schweisshemmende mittel
DE60136571D1 (de)	2008-12-24	Guanidinobenzamide als mc4-r agonisten
DE60317711D1 (de)	2008-01-03	Kationische porphyrin-derivate als antibakterielle mittel
DE60106275D1 (de)	2004-11-11	Dermatologisches mittel
BR0106287B1 (pt)	2009-08-11	seringa de segurança.
DE60132618D1 (de)	2008-03-13	4,6-diphenylpyridinderivate als entzündungshemmende mittel
DE60210598D1 (de)	2006-05-24	3,7-DIAZABICYCLOc3.3.1Ü-FORMULIERUNGEN ALS ANTIARRHYTHMIKA
DE60004207D1 (de)	2003-09-04	Bizyklische oxazolidinone als antibakterielle mittel
NL1027545A1 (nl)	2005-05-23	Chinolonen als antibacteriele middelen.
ATE337322T1 (de)	2006-09-15	Isoxazolin-derivate als antidepressiva
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