ATE383361T1 - Pyrrazolopyrimidinderivate - Google Patents

Pyrrazolopyrimidinderivate

Info

Publication number: ATE383361T1
Authority: AT; Austria
Prior art keywords: pyrrazolopyrimide; derivatives; pyrrazolopyrimide derivatives
Prior art date: 2004-06-21

Application number

AT05754665T

Other languages

English (en)

Inventor

Erwin Goetschi

Juergen Wichmann

Thomas Woltering

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-06-21

Filing date

2005-06-13

Publication date

2008-01-15

2005-06-13 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2008-01-15 Application granted granted Critical

2008-01-15 Publication of ATE383361T1 publication Critical patent/ATE383361T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT05754665T 2004-06-21 2005-06-13 Pyrrazolopyrimidinderivate ATE383361T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP04102837		2004-06-21

Publications (1)

Publication Number	Publication Date
ATE383361T1 true ATE383361T1 (de)	2008-01-15

Family

ID=34971089

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05754665T ATE383361T1 (de)	2004-06-21	2005-06-13	Pyrrazolopyrimidinderivate

Country Status (26)

Country	Link
US (1)	US7378417B2 (de)
EP (1)	EP1761541B1 (de)
JP (1)	JP4608542B2 (de)
CN (1)	CN100528876C (de)
AR (1)	AR049521A1 (de)
AT (1)	ATE383361T1 (de)
AU (1)	AU2005254657B2 (de)
BR (1)	BRPI0512330A (de)
CA (1)	CA2571487C (de)
DE (1)	DE602005004287T2 (de)
DK (1)	DK1761541T3 (de)
ES (1)	ES2299044T3 (de)
HK (1)	HK1105971A1 (de)
HR (1)	HRP20080070T3 (de)
IL (1)	IL179736A (de)
MX (1)	MXPA06014809A (de)
MY (1)	MY143368A (de)
NO (1)	NO20070249L (de)
NZ (1)	NZ551660A (de)
PL (1)	PL1761541T3 (de)
PT (1)	PT1761541E (de)
RU (1)	RU2378277C2 (de)
SI (1)	SI1761541T1 (de)
TW (1)	TWI301835B (de)
WO (1)	WO2005123738A1 (de)
ZA (1)	ZA200610102B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0607927A2 (pt) *	2005-02-11	2009-10-20	Hoffmann La Roche	derivados de pirazol-pirimidina
SI1863818T1 (sl)	2005-03-23	2010-05-31	Hoffmann La Roche	Derivati acetilenil pirazolo pirimidina kot antagonisti mglur
BRPI0616571A2 (pt)	2005-09-27	2011-06-21	Hoffmann La Roche	oxadiazolil pirazol-piridiminas como antagonistas de mglur2, processo para sua preparação, composição farmacêutica que os contém e uso dos mesmo
EP1948663B1 (de) *	2005-10-21	2011-09-14	Exelixis, Inc.	Pyrazolopyrimidine als modulatoren von caseinkinase ii (ck2)
EP2178375B1 (de) *	2007-07-20	2014-09-24	Merck Sharp & Dohme Corp.	Pyrazol-[1,5-a]-pyrimidinderivate
CA2740792C (en) *	2008-10-31	2016-06-21	Genentech, Inc.	Pyrazolopyrimidine jak inhibitor compounds and methods
AR078171A1 (es) *	2009-09-15	2011-10-19	Sanofi Aventis	Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas
WO2012075393A2 (en) *	2010-12-02	2012-06-07	President And Fellows Of Harvard College	Activators of proteasomal degradation and uses thereof
PT3366688T (pt) *	2010-12-08	2022-05-11	Us Health	Pirazolopirimidinas substituídas como ativadores de glucocerebrosidase
US10953012B2 (en)	2011-04-26	2021-03-23	Bioenergenix Llc	Heterocyclic compounds for the inhibition of pask
US9464035B2 (en)	2012-03-28	2016-10-11	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Salicylic acid derivatives useful as glucocerebrosidase activators
SG11201503192XA (en)	2012-10-23	2015-06-29	Hoffmann La Roche	Mglu2/3 antagonists for the treatment of autistic disorders
US10392389B2 (en)	2012-10-25	2019-08-27	Bioenergenix Llc	Heterocyclic compounds for the inhibition of PASK
US9278973B2 (en)	2012-10-25	2016-03-08	Bioenergenix Llc	Heterocyclic compounds for the inhibition of PASK
EP3134089A2 (de)	2014-04-23	2017-03-01	F. Hoffmann-La Roche AG	Mglu2/3-antagonisten zur behandlung von geistigen behinderungen
JOP20150179B1 (ar)	2014-08-01	2021-08-17	Janssen Pharmaceutica Nv	مركبات 6 ، 7 ثاني هيدرو بيرازولو [ 1، 5 الفا ] بيرازين – 4 (5 يد) – اون واستخدامها كمنظمات الوسترية سلبية لمستقبلات ملجور 2
EP3000814A1 (de)	2014-09-26	2016-03-30	Domain Therapeutics	Substituierte Pyrazolochinazolinone und Pyrrolochinazolinone als allosterische Modulatoren von metabotropen Glutamatrezeptoren der Gruppe II
IL252053B2 (en)	2014-11-06	2024-04-01	Lysosomal Therapeutics Inc	Converted pyrazolo[1,5-a]pyrimidines and their use in the treatment of medical disorders
EP3215509B1 (de)	2014-11-06	2020-02-26	Lysosomal Therapeutics Inc.	Substituierte pyrrolo[1,2-a]pyrimidine und deren verwendung bei der behandlung von medizinischen störungen
EP3215510B1 (de)	2014-11-06	2023-06-07	Bial-R&D Investments, S.A.	Substituierte imidazo[1,5-a]pyrimidine und deren verwendung bei der behandlung von medizinischen störungen
AU2015357169B2 (en)	2014-12-03	2021-03-04	Janssen Pharmaceutica Nv	Radiolabelled mGluR2 PET ligands
WO2017066428A1 (en)	2015-10-13	2017-04-20	H. Lee Moffitt Cancer Center & Research Institute, Inc.	Brd4-kinase inhibitors as cancer therapeutics
WO2017103179A1 (en)	2015-12-18	2017-06-22	Janssen Pharmaceutica Nv	Radiolabelled mglur2/3 pet ligands
DK3389727T3 (da)	2015-12-18	2020-11-02	Janssen Pharmaceutica Nv	Radioaktivt mærkede mglur2/3-pet-ligander
CA3020287A1 (en) *	2016-04-06	2017-10-12	Lysosomal Therapeutics Inc.	Pyrazolo[1,5-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders
WO2017176962A1 (en)	2016-04-06	2017-10-12	Lysosomal Therapeutics, Inc.	Pyrrolo[1,2-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders
JP7046827B2 (ja)	2016-04-06	2022-04-04	リソソーマル・セラピューティクス・インコーポレイテッド	イミダゾ［１，５－ａ］ピリミジニルカルボキサミド化合物および医学的障害の処置におけるその使用
WO2017192930A1 (en)	2016-05-05	2017-11-09	Lysosomal Therapeutics Inc.	SUBSTITUTED IMIDAZO[1,2-b]PYRIDAZINES, SUBSTITUTED IMIDAZO[1,5-b]PYRIDAZINES, RELATED COMPOUNDS, AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS
US11345698B2 (en)	2016-05-05	2022-05-31	Bial—R&D Investments, S.A.	Substituted imidazo[1,2-a]pyridines, substituted imidazo[1,2-a]pyrazines, related compounds, and their use in the treatment of medical disorders
WO2020081508A1 (en)	2018-10-15	2020-04-23	Nimbus Lakshmi, Inc.	Tyk2 inhibitors and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5017212A (en) *	1986-03-20	1991-05-21	Takeda Chemical Industries, Ltd.	Sulfonylurea compounds and herbicidal use
PT891978E (pt) *	1997-07-18	2002-07-31	Hoffmann La Roche	Derivados de 5h-tiazolo (3,2-a) pirimidina
EA200200422A1 (ru) *	1999-09-30	2002-10-31	Ньюроджен Корпорейшн	НЕКОТОРЫЕ АЛКИЛЕНДИАМИНОЗАМЕЩЕННЫЕ ПИРАЗОЛО[1,5-а]-1,5-ПИРИМИДИНЫ И ПИРАЗОЛО[1,5-а]-1,3,5-ТРИАЗИНЫ
ATE374200T1 (de) *	2002-03-28	2007-10-15	Eisai R&D Man Co Ltd	7-azaindole als inhibitoren c-jun n-terminaler kinasen zur behandlung neurodegenerativer störungen
US7329662B2 (en) *	2003-10-03	2008-02-12	Hoffmann-La Roche Inc.	Pyrazolo-pyridine

2005
- 2005-06-13 DK DK05754665T patent/DK1761541T3/da active
- 2005-06-13 SI SI200530203T patent/SI1761541T1/sl unknown
- 2005-06-13 PL PL05754665T patent/PL1761541T3/pl unknown
- 2005-06-13 AU AU2005254657A patent/AU2005254657B2/en not_active Ceased
- 2005-06-13 BR BRPI0512330-5A patent/BRPI0512330A/pt not_active IP Right Cessation
- 2005-06-13 NZ NZ551660A patent/NZ551660A/en unknown
- 2005-06-13 MX MXPA06014809A patent/MXPA06014809A/es active IP Right Grant
- 2005-06-13 ES ES05754665T patent/ES2299044T3/es active Active
- 2005-06-13 CA CA2571487A patent/CA2571487C/en not_active Expired - Fee Related
- 2005-06-13 AT AT05754665T patent/ATE383361T1/de active
- 2005-06-13 WO PCT/EP2005/006302 patent/WO2005123738A1/en active IP Right Grant
- 2005-06-13 PT PT05754665T patent/PT1761541E/pt unknown
- 2005-06-13 CN CNB2005800187943A patent/CN100528876C/zh not_active Expired - Fee Related
- 2005-06-13 RU RU2006143571/04A patent/RU2378277C2/ru not_active IP Right Cessation
- 2005-06-13 JP JP2007517134A patent/JP4608542B2/ja not_active Expired - Fee Related
- 2005-06-13 DE DE602005004287T patent/DE602005004287T2/de active Active
- 2005-06-13 EP EP05754665A patent/EP1761541B1/de active Active
- 2005-06-17 AR ARP050102490A patent/AR049521A1/es not_active Application Discontinuation
- 2005-06-20 MY MYPI20052792A patent/MY143368A/en unknown
- 2005-06-20 TW TW094120365A patent/TWI301835B/zh not_active IP Right Cessation
- 2005-06-20 US US11/156,974 patent/US7378417B2/en not_active Expired - Fee Related
2006
- 2006-11-30 IL IL179736A patent/IL179736A/en not_active IP Right Cessation
- 2006-12-01 ZA ZA200610102A patent/ZA200610102B/xx unknown
2007
- 2007-01-15 NO NO20070249A patent/NO20070249L/no not_active Application Discontinuation
- 2007-10-22 HK HK07111355.9A patent/HK1105971A1/xx not_active IP Right Cessation
2008
- 2008-02-13 HR HR20080070T patent/HRP20080070T3/xx unknown

Also Published As

Publication number	Publication date
CN1964973A (zh)	2007-05-16
TW200626598A (en)	2006-08-01
SI1761541T1 (sl)	2008-06-30
US20050282827A1 (en)	2005-12-22
HRP20080070T3 (en)	2008-05-31
WO2005123738A1 (en)	2005-12-29
HK1105971A1 (en)	2008-02-29
AR049521A1 (es)	2006-08-09
EP1761541B1 (de)	2008-01-09
US7378417B2 (en)	2008-05-27
DE602005004287D1 (de)	2008-02-21
RU2006143571A (ru)	2008-07-27
NO20070249L (no)	2007-02-15
CA2571487C (en)	2013-04-30
TWI301835B (en)	2008-10-11
RU2378277C2 (ru)	2010-01-10
DK1761541T3 (da)	2008-04-28
CA2571487A1 (en)	2005-12-29
JP4608542B2 (ja)	2011-01-12
NZ551660A (en)	2009-08-28
AU2005254657A1 (en)	2005-12-29
BRPI0512330A (pt)	2008-02-26
AU2005254657B2 (en)	2011-03-17
JP2008503510A (ja)	2008-02-07
IL179736A (en)	2010-12-30
DE602005004287T2 (de)	2008-12-24
CN100528876C (zh)	2009-08-19
IL179736A0 (en)	2007-05-15
MXPA06014809A (es)	2007-02-12
ES2299044T3 (es)	2008-05-16
PL1761541T3 (pl)	2008-06-30
MY143368A (en)	2011-04-29
EP1761541A1 (de)	2007-03-14
PT1761541E (pt)	2008-03-13
ZA200610102B (en)	2008-08-27

Publication	Publication Date	Title
NO2017018I1 (no)	2017-05-04	umeklinidiumbromid
IS8578A (is)	2006-12-08	3- karbamoýl - 2- pýridón afleiður
DK1725553T3 (da)	2008-08-18	Tetrahydropyridoindolderivater
ATE540935T1 (de)	2012-01-15	Chinazolinderivate
ATE383361T1 (de)	2008-01-15	Pyrrazolopyrimidinderivate
ATE417830T1 (de)	2009-01-15	Sulfonylbenzimidazolderivate
ATE553079T1 (de)	2012-04-15	Heteroarylphenylharnstoffderivat
NO20052187L (no)	2005-11-14	Repetervapen
DE602006010581D1 (de)	2009-12-31	4-phenyl-6-substituierte pyrimidin-2-carbonitrilderivate
DE602005003991D1 (de)	2008-02-07	Gleichlauftripodegelenk
DE602004004628D1 (de)	2007-03-22	Schlauchendsprühgerät
ATE485294T1 (de)	2010-11-15	Azaindol-2-carboxamid-derivate
DE602005026084D1 (de)	2011-03-10	Tintenstrahlkopfanornung
ATE430142T1 (de)	2009-05-15	Phenylpiperazin-methanon-derivate
ATE527255T1 (de)	2011-10-15	Aryl-isoxazol-4-yl-imidazol-derivate
DK1971588T3 (da)	2012-10-22	Tiglien-3-onderivater
DE602004017368D1 (de)	2008-12-04	Verschliessmaschinenkopf
ATE404542T1 (de)	2008-08-15	4-phenylpyrimidin-2-carbonitrilderivate
DE602005007544D1 (de)	2008-07-31	Perfluoroelastomergele
DK1740574T3 (da)	2007-10-15	4-amino-5-cyanopyrimidinderivater
DE502005004695D1 (de)	2008-08-28	Sicherheitsfangseil
ATE541837T1 (de)	2012-02-15	Oxaphenanthren-derivate
FI20045304A (fi)	2004-08-24	Repijämurskain
DE502005003159D1 (de)	2008-04-24	Kettenstichnähvorrichtung
DE602004013423D1 (de)	2008-06-12	Kraftstoffverteilerkomponent

Legal Events

Date	Code	Title	Description
2008-08-15	UEP	Publication of translation of european patent specification	Ref document number: 1761541 Country of ref document: EP

Date

Code

Title

Description

2008-08-15

UEP

Publication of translation of european patent specification

Ref document number: 1761541

Country of ref document: EP