Nothing Special   »   [go: up one dir, main page]

ATE381349T1 - Bioabbaubare polyester zur herstellung ionischer molekularer konjugate mit bioaktiven polypeptiden - Google Patents

Bioabbaubare polyester zur herstellung ionischer molekularer konjugate mit bioaktiven polypeptiden

Info

Publication number
ATE381349T1
ATE381349T1 AT02001064T AT02001064T ATE381349T1 AT E381349 T1 ATE381349 T1 AT E381349T1 AT 02001064 T AT02001064 T AT 02001064T AT 02001064 T AT02001064 T AT 02001064T AT E381349 T1 ATE381349 T1 AT E381349T1
Authority
AT
Austria
Prior art keywords
acid
lactide
biodegradable polyesters
molecular conjugates
bioactive polypeptides
Prior art date
Application number
AT02001064T
Other languages
English (en)
Inventor
Shalaby W Shalaby
Steven A Jackson
Jacques-Pierre Moreau
Original Assignee
Ipsen Mfg Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Mfg Ireland Ltd filed Critical Ipsen Mfg Ireland Ltd
Application granted granted Critical
Publication of ATE381349T1 publication Critical patent/ATE381349T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/04Polyesters derived from hydroxycarboxylic acids, e.g. lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593Polyesters, e.g. PLGA or polylactide-co-glycolide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/23Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00Compositions of proteins; Compositions of derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Biological Depolymerization Polymers (AREA)
AT02001064T 1993-01-06 1994-01-05 Bioabbaubare polyester zur herstellung ionischer molekularer konjugate mit bioaktiven polypeptiden ATE381349T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IE930005 1993-01-06

Publications (1)

Publication Number Publication Date
ATE381349T1 true ATE381349T1 (de) 2008-01-15

Family

ID=38859740

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02001064T ATE381349T1 (de) 1993-01-06 1994-01-05 Bioabbaubare polyester zur herstellung ionischer molekularer konjugate mit bioaktiven polypeptiden

Country Status (4)

Country Link
EP (1) EP1203591B1 (de)
AT (1) ATE381349T1 (de)
DE (1) DE69435055T2 (de)
IE (1) IES61251B2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115785403B (zh) * 2022-12-02 2024-05-14 南方医科大学 一种苹果酸基生物材料及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9310030D0 (en) * 1993-05-15 1993-06-30 Scras Dry processed particles and process for the preparation of the same

Also Published As

Publication number Publication date
EP1203591B1 (de) 2007-12-19
EP1203591A1 (de) 2002-05-08
IES940005A2 (en) 1994-07-13
DE69435055T2 (de) 2008-12-04
DE69435055D1 (de) 2008-01-31
IES61251B2 (en) 1994-10-19

Similar Documents

Publication Publication Date Title
RU99122608A (ru) Сложный полиэфир и композиция на его основе
EP0139576A3 (de) Bioresorbierbare Polyester und Polyesterverbundstoffe
NO984923L (no) Sure polymelkesyrepolymerer
ATE168889T1 (de) Bioresorbierbares material und aus diesem material hergestellter gegenstand
BR9400436A (pt) Polímero, sutura e artigo cirúrgico
CY1111357T1 (el) Τυποποιησεις αποθεματος ιλοπεριδονης και πολυμερους αστερα
ATE445423T1 (de) Absorbierbare polymere und daraus hergestellte chirurgische artikel
DE69230460D1 (de) Verfahren zur Herstellung von wasserlöslichen und/oder wasserdispergierbaren Polyestern und die Verwendung dieser Polyester zum Schlichten von Textilgarnen
ATE375374T1 (de) Copolymere aus bioabbaubaren aliphatischen polyestern
DE59510379D1 (de) Polyesterpolyole und ihre Verwendung in Zweikomponenten-Polyurethanlacken
NO981251L (no) Polyesterformsammensetninger
CA2205422A1 (en) Absorbable polyalkylene diglycolates
DE69835189D1 (de) Biodegradierbarer selbstexpandierender Stent
DE60121602D1 (de) Verfahren zur umsetzung von linearen polyestern in makrozyklischen oligoester-zusammensetzungen und makrozyklische oligoester
IE840121L (en) Absorbable polymers of substituted benzoic acid.
KR960703719A (ko) 수축성 코폴리에스테르 필름(shrinkable copolyester film)
KR900013010A (ko) 폴리에스테르 수지조성물
ATE381349T1 (de) Bioabbaubare polyester zur herstellung ionischer molekularer konjugate mit bioaktiven polypeptiden
NO955089D0 (no) Delkrystallinsk blokk-kopolyester-polyamid
DE69418128D1 (de) Copolymere aus (p-Dioxanone/Glycolide und/oder Lactid) und p-Dioxanon
KR910700288A (ko) 폴리에스테르 공중합체
RU2003128961A (ru) Способ получения полиэфиров со свободными кислотными функциями внутри цепи
DE3876218D1 (de) Neue polyesterpolyole und ihre verwendung als polyol-komponente in zweikomponenten-polyurethanlacken.
SE9503799D0 (sv) Bio-degradable/absorbable barrier membrane
CA2347790A1 (en) Absorbable polymers and surgical articles fabricated therefrom

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties