ATE345135T1 - Tropan-derivate mit dopamin-wiederaufnahme-hemmer-wirkung für die behandlung von ischämischen erkrankungen - Google Patents
Tropan-derivate mit dopamin-wiederaufnahme-hemmer-wirkung für die behandlung von ischämischen erkrankungenInfo
- Publication number
- ATE345135T1 ATE345135T1 AT02803752T AT02803752T ATE345135T1 AT E345135 T1 ATE345135 T1 AT E345135T1 AT 02803752 T AT02803752 T AT 02803752T AT 02803752 T AT02803752 T AT 02803752T AT E345135 T1 ATE345135 T1 AT E345135T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- dopamine
- rupup
- ischemic diseases
- tropane derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200101781 | 2001-11-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE345135T1 true ATE345135T1 (de) | 2006-12-15 |
Family
ID=8160868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02803752T ATE345135T1 (de) | 2001-11-30 | 2002-11-28 | Tropan-derivate mit dopamin-wiederaufnahme-hemmer-wirkung für die behandlung von ischämischen erkrankungen |
Country Status (7)
Country | Link |
---|---|
US (1) | US7381733B2 (de) |
EP (1) | EP1453511B1 (de) |
JP (1) | JP2005511639A (de) |
AT (1) | ATE345135T1 (de) |
AU (1) | AU2002365288A1 (de) |
DE (1) | DE60216142T2 (de) |
WO (1) | WO2003045388A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2480742A1 (en) * | 2002-03-28 | 2003-12-04 | President And Fellows Of Harvard College | Tropane compounds |
NZ541248A (en) * | 2003-02-12 | 2008-04-30 | Neurosearch As | Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
AR045141A1 (es) | 2003-07-31 | 2005-10-19 | Neurosearch As | Sales de tartrato de 2- metoximetil-3-(3,4-diclorofenil)-8-azabiciclo (3,2,1) octano. composiciones farmaceuticas que los contienen y usos de las mismas. |
BRPI0416691A (pt) * | 2003-11-18 | 2007-01-30 | Boehringer Ingelheim Int | forma de preparação farmacêutica sólida |
DE102004004965B4 (de) * | 2004-01-31 | 2006-01-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung eines 2-(Ethoxymethyl)-tropanderivates |
CA2614833A1 (en) * | 2005-07-12 | 2007-01-18 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition comprising 2, 3-disubstituted tropanes for the treatment of disorders of sexual desire |
GB0703998D0 (en) * | 2007-03-01 | 2007-04-11 | Glaxo Group Ltd | Novel salt |
US8221345B2 (en) | 2007-05-30 | 2012-07-17 | Smiths Medical Asd, Inc. | Insulin pump based expert system |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4179567A (en) * | 1978-04-10 | 1979-12-18 | Sterling Drug Inc. | 2-Aryltropane compounds |
US5272160A (en) * | 1989-05-17 | 1993-12-21 | Pfizer Inc | 2-piperidino-1-alkanol derivatives as antiischemic agents |
US6329520B1 (en) * | 1990-08-09 | 2001-12-11 | Research Triangle Institute | Cocaine receptor binding ligands |
US5128118A (en) * | 1990-08-09 | 1992-07-07 | Research Triangle Institute | Cocaine receptor binding ligands |
AU671163B2 (en) | 1992-12-23 | 1996-08-15 | Neurosearch A/S | Alkyl substituted heterocyclic compounds |
AU672052B2 (en) | 1992-12-23 | 1996-09-19 | Neurosearch A/S | Antidepressant and antiparkinsonian compounds |
DK154192D0 (da) * | 1992-12-23 | 1992-12-23 | Neurosearch As | Heterocycliske forbindelser |
AU672644B2 (en) | 1992-12-23 | 1996-10-10 | Neurosearch A/S | Aryl substituted heterocyclic compounds |
CZ284379B6 (cs) | 1994-04-19 | 1998-11-11 | Neurosearch A/S | Tropanové deriváty, způsob jejich přípravy a jejich použití |
AU684359B2 (en) | 1994-08-18 | 1997-12-11 | Pfizer Inc. | Neuroprotective 3-(piperidinyl-1)-chroman-4,7-diol and 1-(4-hydrophenyl)-2-(piperidinyl-1)-alkanol derivatives |
US6241963B1 (en) * | 1995-10-19 | 2001-06-05 | The Trustees Of The University Of Pennsylvania | Dopamine and serotonin transporter ligands and imaging agents |
DK0858461T3 (da) | 1995-11-02 | 2003-01-27 | Neurosearch As | Kondenserede tropanderivater som neurotransmittergenoptagelsesinhibitorer |
ATE203023T1 (de) | 1996-02-22 | 2001-07-15 | Neurosearch As | Tropanderivate, deren herstellung und verwendung |
AU7847800A (en) * | 1999-10-15 | 2001-04-30 | Mayo Foundation For Medical Education And Research | Topical anesthetics useful for treating cancer, autoimmune diseases and ischemia |
EP1361874A1 (de) * | 2001-02-15 | 2003-11-19 | Neurosearch A/S | Behandlung von durch übermässigen oder unzureichendem zelltod gekennzeichneten erkrankungen |
-
2002
- 2002-11-28 AT AT02803752T patent/ATE345135T1/de not_active IP Right Cessation
- 2002-11-28 EP EP02803752A patent/EP1453511B1/de not_active Expired - Lifetime
- 2002-11-28 DE DE60216142T patent/DE60216142T2/de not_active Expired - Lifetime
- 2002-11-28 AU AU2002365288A patent/AU2002365288A1/en not_active Abandoned
- 2002-11-28 JP JP2003546890A patent/JP2005511639A/ja active Pending
- 2002-11-28 US US10/494,922 patent/US7381733B2/en not_active Expired - Fee Related
- 2002-11-28 WO PCT/DK2002/000796 patent/WO2003045388A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
WO2003045388A1 (en) | 2003-06-05 |
EP1453511A1 (de) | 2004-09-08 |
US20050020621A1 (en) | 2005-01-27 |
DE60216142T2 (de) | 2007-09-06 |
DE60216142D1 (de) | 2006-12-28 |
AU2002365288A1 (en) | 2003-06-10 |
EP1453511B1 (de) | 2006-11-15 |
US7381733B2 (en) | 2008-06-03 |
JP2005511639A (ja) | 2005-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |