ATE239722T1 - Benzofurylpiperazine als serotonin-agonisten - Google Patents

Benzofurylpiperazine als serotonin-agonisten

Info

Publication number: ATE239722T1
Authority: AT; Austria
Prior art keywords: benzofurylpiperazine; serotonin agonists; serotonin; agonists; benzofurans
Prior art date: 1999-07-29

Application number

AT00948746T

Other languages

English (en)

Inventor

Karin Briner

Timothy Paul Burkholder

Mark Louis Heiman

David Lloyd Garver Nelson

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-07-29

Filing date

2000-07-21

Publication date

2003-05-15

2000-07-21 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE239722T1 publication Critical patent/ATE239722T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT00948746T 1999-07-29 2000-07-21 Benzofurylpiperazine als serotonin-agonisten ATE239722T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US14628799P	1999-07-29	1999-07-29
US17216999P	1999-12-17	1999-12-17
PCT/US2000/019545 WO2001009123A1 (en)	1999-07-29	2000-07-21	Benzofurylpiperazine serotonin agonists

Publications (1)

Publication Number	Publication Date
ATE239722T1 true ATE239722T1 (de)	2003-05-15

Family

ID=26843756

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00948746T ATE239722T1 (de)	1999-07-29	2000-07-21	Benzofurylpiperazine als serotonin-agonisten

Country Status (11)

Country	Link
US (1)	US6638936B1 (de)
EP (1)	EP1204658B1 (de)
JP (1)	JP2003506370A (de)
AT (1)	ATE239722T1 (de)
AU (1)	AU6220300A (de)
CA (1)	CA2380531A1 (de)
DE (1)	DE60002583T2 (de)
DK (1)	DK1204658T3 (de)
ES (1)	ES2198329T3 (de)
PT (1)	PT1204658E (de)
WO (1)	WO2001009123A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1365359A (zh) *	1999-07-29	2002-08-21	伊莱利利公司	苯并呋喃哌嗪和苯并呋喃基高哌嗪:血清素激动剂
CN1227237C (zh)	2000-11-20	2005-11-16	比奥维特罗姆股份公司	作为五羟色胺5－ht2受体拮抗剂的哌嗪基吡嗪化合物
SE0004245D0 (sv)	2000-11-20	2000-11-20	Pharmacia Ab	Novel compounds and their use
DK1408976T5 (da) *	2001-07-20	2011-01-10	Psychogenics Inc	Behandling af ADHD (Attention deficit hyperactivity disorder)
NZ536664A (en)	2002-06-19	2007-07-27	Biovitrum Ab	Piperazinylpyrazine derivative compounds, their use and preparation
US8685924B2 (en)	2004-08-25	2014-04-01	Takeda Pharmaceutical Company Limited	Preventives/remedies for stress urinary incontinence and method of screening the same
EP2018863B9 (de)	2006-05-16	2015-02-18	Takeda Pharmaceutical Company Limited	Kondensierte, heterocyclische Verbindung und ihre Verwendung
CL2007003065A1 (es) *	2006-10-24	2008-01-25	Wyeth Corp	Compuestos derivados de benzodioxano, agonista 5ht2c, composicion farmaceutica que lois comprende; y sus uso en el tratamiento de un trastorno psicotico, ansiedad, depresion, trastorno bipolar, sindrome premenstrual, entre otros
EP2789338A3 (de)	2007-11-15	2015-01-14	Takeda Pharmaceutical Company Limited	Kondensiertes Pyridinderivat und seine Verwendung
EP2510949A4 (de)	2009-12-11	2013-11-13	Astellas Pharma Inc	Therapeutikum für fibromyalgie
WO2015066344A1 (en)	2013-11-01	2015-05-07	Arena Pharmaceuticals, Inc.	5-ht2c receptor agonists and compositions and methods of use
EP3733204A4 (de)	2017-12-27	2021-09-15	Takeda Pharmaceutical Company Limited	Therapeutikum für belastungsinkontinenz und stuhlinkontinenz

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0006524A1 (de) *	1978-06-22	1980-01-09	Ciba-Geigy Ag	Neue Tetrahydropyridin- und Piperidinderivate und deren Säureadditionssalze, Verfahren zu deren Herstellung und solche enthaltende pharmazeutische Zusammensetzungen
DE3586794T2 (de) *	1984-12-21	1993-05-27	Duphar Int Res	Arzneimittel mit psychotroper wirkung.
JPH09503773A (ja)	1993-10-19	1997-04-15	スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー	５ｈｔ−１ｄレセプター拮抗剤用のベンズアニリド誘導体
US5698766A (en)	1995-04-05	1997-12-16	The Regents Of The University Of California	Transgenic animal model for testing drugs for treating eating disorders and epilepsy
GB9517559D0 (en) *	1995-08-26	1995-10-25	Smithkline Beecham Plc	Novel compounds
ATE340173T1 (de) *	1996-03-29	2006-10-15	Duphar Int Res	Piperazin- und piperidin- derivate
US6132538A (en)	1998-07-30	2000-10-17	Autoliv Development Ab	High gas yield generant compositions
GB0012165D0 (en)	2000-05-20	2000-07-12	Team Consulting Ltd	Portable device with consistent power output

2000
- 2000-07-21 EP EP00948746A patent/EP1204658B1/de not_active Expired - Lifetime
- 2000-07-21 CA CA002380531A patent/CA2380531A1/en not_active Abandoned
- 2000-07-21 US US10/031,310 patent/US6638936B1/en not_active Expired - Fee Related
- 2000-07-21 WO PCT/US2000/019545 patent/WO2001009123A1/en active IP Right Grant
- 2000-07-21 PT PT00948746T patent/PT1204658E/pt unknown
- 2000-07-21 JP JP2001514326A patent/JP2003506370A/ja not_active Withdrawn
- 2000-07-21 DK DK00948746T patent/DK1204658T3/da active
- 2000-07-21 AT AT00948746T patent/ATE239722T1/de not_active IP Right Cessation
- 2000-07-21 DE DE60002583T patent/DE60002583T2/de not_active Expired - Fee Related
- 2000-07-21 ES ES00948746T patent/ES2198329T3/es not_active Expired - Lifetime
- 2000-07-21 AU AU62203/00A patent/AU6220300A/en not_active Abandoned

Also Published As

Publication number	Publication date
JP2003506370A (ja)	2003-02-18
US6638936B1 (en)	2003-10-28
AU6220300A (en)	2001-02-19
DK1204658T3 (da)	2003-09-01
CA2380531A1 (en)	2001-02-08
DE60002583D1 (de)	2003-06-12
EP1204658B1 (de)	2003-05-07
EP1204658A1 (de)	2002-05-15
DE60002583T2 (de)	2004-03-25
PT1204658E (pt)	2003-08-29
WO2001009123A1 (en)	2001-02-08
ES2198329T3 (es)	2004-02-01

Publication	Publication Date	Title
NL300877I2 (nl)	2017-06-22	obeticholzuur
ATE297910T1 (de)	2005-07-15	Retinoid x rezeptormodulatoren
BR0114045A (pt)	2003-07-01	Poliarilcarboxamidas úteis como agentes redutores de lipìdeos
DK1204654T3 (da)	2003-11-17	Benzofurylpiperaziner og benzofurylhomopiperaziner: Serotonin agonister
HRP20090162T1 (en)	2009-05-31	Quinolinone-carboxamide compounds as 5-ht4 receptor agonists
TR200200579T2 (tr)	2002-12-23	Amino-tirazolpiridin türevleri.
DE60107449D1 (de)	2004-12-30	Substituierte aminopropoxyarylderivate als lxr agonisten
ATE506354T1 (de)	2011-05-15	Substituierte arylcyclopropylacetamide als glucokinaseaktivatoren
HRP20090281T1 (en)	2009-06-30	1,2,3,4-tetrasubstituted indole for the treatment of respiratory diseases
ATE302775T1 (de)	2005-09-15	Carbolinderivate
DE60121461D1 (de)	2006-08-24	Kondensierte pyridoindolderivate
EA200300619A1 (ru)	2003-10-30	Серотонинергические средства
ATE346067T1 (de)	2006-12-15	Carbolinderivate
DE602004009200D1 (de)	2007-11-08	Tetrahydrochinazolinderivate als cfr-antagonisten
ATE300543T1 (de)	2005-08-15	Kondensierte pyrazindionderivate als pde5 inhibitore
ATE239722T1 (de)	2003-05-15	Benzofurylpiperazine als serotonin-agonisten
DE60112960D1 (de)	2005-09-29	Kondensierte pyridoindolderivate
ATE333457T1 (de)	2006-08-15	Zyklische gmp-spezifische phosphodiesteraseinhibitoren
BR0208812A (pt)	2004-03-09	Derivados fenil heterociclil éter como inibidores de recaptação de serotonina
PT1204659E (pt)	2004-04-30	Benzofuranos serotoninergicos
ATE284882T1 (de)	2005-01-15	Chromenylmethylpyrimidindiamine als antibakterielle wirkstoffe
ATE293111T1 (de)	2005-04-15	Kondensierte pyrazindionderivate als pde inhibitoren
RS50033B (sr)	2008-11-28	Derivati etansulfonil-piperidina
DE60121048D1 (de)	2006-08-03	PYRAZINOi1'2':1,6öPYRIDOi3,4-BöINDOLDERIVATE
DE60227113D1 (de)	2008-07-24	Kondensierte camptothecine als antitumormittel

Legal Events

Date	Code	Title	Description
2004-03-15	UEP	Publication of translation of european patent specification	Ref document number: 1204658 Country of ref document: EP
2006-04-15	REN	Ceased due to non-payment of the annual fee

Date

Code

Title

Description

2004-03-15

UEP

Publication of translation of european patent specification

Ref document number: 1204658

Country of ref document: EP

2006-04-15

REN

Ceased due to non-payment of the annual fee