ATE232848T1 - Benzoesäurederivate und deren medizinische verwendung - Google Patents
Benzoesäurederivate und deren medizinische verwendungInfo
- Publication number
- ATE232848T1 ATE232848T1 AT98907277T AT98907277T ATE232848T1 AT E232848 T1 ATE232848 T1 AT E232848T1 AT 98907277 T AT98907277 T AT 98907277T AT 98907277 T AT98907277 T AT 98907277T AT E232848 T1 ATE232848 T1 AT E232848T1
- Authority
- AT
- Austria
- Prior art keywords
- compound
- serotonin
- pharmaceutically acceptable
- gastrointestinal
- agent
- Prior art date
Links
- 150000001558 benzoic acid derivatives Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 2
- NJORREFJHWQEKY-UHFFFAOYSA-N 4-amino-n-[[1-(3-benzylsulfonylpropyl)piperidin-4-yl]methyl]-5-chloro-2-methoxybenzamide Chemical compound COC1=CC(N)=C(Cl)C=C1C(=O)NCC1CCN(CCCS(=O)(=O)CC=2C=CC=CC=2)CC1 NJORREFJHWQEKY-UHFFFAOYSA-N 0.000 abstract 1
- 108091005482 5-HT4 receptors Proteins 0.000 abstract 1
- -1 N-oxide compound Chemical class 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 230000004217 heart function Effects 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000002325 prokinetic agent Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000387 serotonin 5-HT4 receptor agonist Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 208000014001 urinary system disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6873997 | 1997-03-21 | ||
| PCT/JP1998/001132 WO1998042668A1 (fr) | 1997-03-21 | 1998-03-16 | Composes d'acide benzoique et leur utilisation medicale |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE232848T1 true ATE232848T1 (de) | 2003-03-15 |
Family
ID=13382468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98907277T ATE232848T1 (de) | 1997-03-21 | 1998-03-16 | Benzoesäurederivate und deren medizinische verwendung |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0979818B1 (de) |
| AT (1) | ATE232848T1 (de) |
| DE (1) | DE69811487D1 (de) |
| WO (1) | WO1998042668A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2897946T3 (es) * | 2013-07-25 | 2022-03-03 | Dong A St Co Ltd | Método para preparar un derivado de benzamida, intermedio novedoso utilizado en la preparación de la benzamida y método para preparar un intermedio novedoso |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0774460A1 (de) * | 1994-03-30 | 1997-05-21 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzosäurederivate und ihre medizinische verwendung |
| JPH0977742A (ja) * | 1995-09-12 | 1997-03-25 | Kyorin Pharmaceut Co Ltd | 新規なベンズアミド誘導体 |
| WO1997011054A1 (en) * | 1995-09-22 | 1997-03-27 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzoic acid compounds and medicinal use thereof |
| JPH09241241A (ja) * | 1996-03-08 | 1997-09-16 | Roussel Morishita Kk | Ｎ−（１−置換−４−ピペリジル）ベンズアミド誘導体 |
-
1998
- 1998-03-16 DE DE69811487T patent/DE69811487D1/de not_active Expired - Lifetime
- 1998-03-16 AT AT98907277T patent/ATE232848T1/de not_active IP Right Cessation
- 1998-03-16 EP EP98907277A patent/EP0979818B1/de not_active Expired - Lifetime
- 1998-03-16 WO PCT/JP1998/001132 patent/WO1998042668A1/ja active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP0979818A4 (de) | 2000-05-31 |
| DE69811487D1 (de) | 2003-03-27 |
| EP0979818A1 (de) | 2000-02-16 |
| WO1998042668A1 (fr) | 1998-10-01 |
| EP0979818B1 (de) | 2003-02-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |