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ATE203023T1 - Tropanderivate, deren herstellung und verwendung - Google Patents

Tropanderivate, deren herstellung und verwendung

Info

Publication number
ATE203023T1
ATE203023T1 AT97903355T AT97903355T ATE203023T1 AT E203023 T1 ATE203023 T1 AT E203023T1 AT 97903355 T AT97903355 T AT 97903355T AT 97903355 T AT97903355 T AT 97903355T AT E203023 T1 ATE203023 T1 AT E203023T1
Authority
AT
Austria
Prior art keywords
derivatives
disorders
tropande
production
monoamine neurotransmitter
Prior art date
Application number
AT97903355T
Other languages
English (en)
Inventor
Joergen Scheel-Krueger
Peter Moldt
Frank Waetjen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Application granted granted Critical
Publication of ATE203023T1 publication Critical patent/ATE203023T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT97903355T 1996-02-22 1997-02-21 Tropanderivate, deren herstellung und verwendung ATE203023T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK19496 1996-02-22
PCT/EP1997/000850 WO1997030997A1 (en) 1996-02-22 1997-02-21 Tropane-derivatives, their preparation and use

Publications (1)

Publication Number Publication Date
ATE203023T1 true ATE203023T1 (de) 2001-07-15

Family

ID=8090830

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97903355T ATE203023T1 (de) 1996-02-22 1997-02-21 Tropanderivate, deren herstellung und verwendung

Country Status (32)

Country Link
US (3) US6288079B1 (de)
EP (2) EP1130020A1 (de)
JP (1) JP3238414B2 (de)
KR (1) KR100446571B1 (de)
CN (1) CN1077574C (de)
AT (1) ATE203023T1 (de)
AU (1) AU720358B2 (de)
BG (1) BG63945B1 (de)
BR (1) BR9707636A (de)
CA (1) CA2244773C (de)
CZ (1) CZ287007B6 (de)
DE (1) DE69705608T2 (de)
DK (1) DK0885220T3 (de)
EE (1) EE04751B1 (de)
ES (1) ES2159839T3 (de)
GR (1) GR3036829T3 (de)
HK (1) HK1018957A1 (de)
HU (1) HU228356B1 (de)
IL (1) IL125146A (de)
IS (1) IS1824B (de)
NO (1) NO318731B1 (de)
NZ (1) NZ330886A (de)
PL (1) PL185132B1 (de)
PT (1) PT885220E (de)
RU (1) RU2167876C2 (de)
SG (1) SG99853A1 (de)
SI (1) SI0885220T1 (de)
SK (1) SK281813B6 (de)
TR (1) TR199801641T2 (de)
UA (1) UA49872C2 (de)
WO (1) WO1997030997A1 (de)
ZA (1) ZA971525B (de)

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CN115572289A (zh) * 2022-10-24 2023-01-06 龙曦宁(上海)医药科技有限公司 一种特索芬辛的合成方法
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Also Published As

Publication number Publication date
HK1018957A1 (en) 2000-01-14
DE69705608D1 (de) 2001-08-16
EE04751B1 (et) 2006-12-15
US6288079B1 (en) 2001-09-11
CN1211982A (zh) 1999-03-24
AU1794097A (en) 1997-09-10
NZ330886A (en) 1999-02-25
JP3238414B2 (ja) 2001-12-17
EE9800254A (et) 1999-02-15
CA2244773C (en) 2006-01-03
BG63945B1 (bg) 2003-07-31
IS4825A (is) 1998-08-17
CZ287007B6 (en) 2000-08-16
HUP9901199A2 (hu) 1999-08-30
PT885220E (pt) 2001-11-30
SI0885220T1 (en) 2001-12-31
EP1130020A1 (de) 2001-09-05
RU2167876C2 (ru) 2001-05-27
EP0885220B1 (de) 2001-07-11
BR9707636A (pt) 1999-07-27
AU720358B2 (en) 2000-06-01
SK281813B6 (sk) 2001-08-06
US6395748B2 (en) 2002-05-28
CZ252098A3 (cs) 1998-11-11
SK92998A3 (en) 1998-11-04
CA2244773A1 (en) 1997-08-28
PL185132B1 (pl) 2003-02-28
ZA971525B (en) 1997-10-21
US20010018444A1 (en) 2001-08-30
CN1077574C (zh) 2002-01-09
WO1997030997A1 (en) 1997-08-28
KR19990087127A (ko) 1999-12-15
TR199801641T2 (xx) 1998-11-23
DK0885220T3 (da) 2001-10-15
SG99853A1 (en) 2003-11-27
HUP9901199A3 (en) 2001-02-28
NO983877D0 (no) 1998-08-21
DE69705608T2 (de) 2002-05-16
JP2000504739A (ja) 2000-04-18
EP0885220A1 (de) 1998-12-23
US20020128284A1 (en) 2002-09-12
KR100446571B1 (ko) 2004-11-03
ES2159839T3 (es) 2001-10-16
UA49872C2 (uk) 2002-10-15
BG102637A (en) 1999-06-30
GR3036829T3 (en) 2002-01-31
IL125146A (en) 2002-03-10
NO318731B1 (no) 2005-05-02
IS1824B (is) 2002-10-01
IL125146A0 (en) 1999-01-26
NO983877L (no) 1998-08-21
PL328503A1 (en) 1999-02-01
HU228356B1 (en) 2013-03-28

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