ATE264307T1 - Interkalatoren mit affinität für dna und ihre anwendung - Google Patents
Interkalatoren mit affinität für dna und ihre anwendungInfo
- Publication number
- ATE264307T1 ATE264307T1 AT94922010T AT94922010T ATE264307T1 AT E264307 T1 ATE264307 T1 AT E264307T1 AT 94922010 T AT94922010 T AT 94922010T AT 94922010 T AT94922010 T AT 94922010T AT E264307 T1 ATE264307 T1 AT E264307T1
- Authority
- AT
- Austria
- Prior art keywords
- intercalators
- affinity
- dna
- applications
- hetero
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/14—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C07D221/12—Phenanthridines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8628593A | 1993-06-30 | 1993-06-30 | |
| PCT/US1994/007130 WO1995001341A1 (en) | 1993-06-30 | 1994-06-23 | Intercalators having affinity for dna and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE264307T1 true ATE264307T1 (de) | 2004-04-15 |
Family
ID=22197554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94922010T ATE264307T1 (de) | 1993-06-30 | 1994-06-23 | Interkalatoren mit affinität für dna und ihre anwendung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5582984A (de) |
| EP (3) | EP0706515B1 (de) |
| JP (1) | JP3856463B2 (de) |
| AT (1) | ATE264307T1 (de) |
| CA (1) | CA2162382C (de) |
| DE (2) | DE69435240D1 (de) |
| ES (2) | ES2218527T3 (de) |
| WO (1) | WO1995001341A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5861247A (en) * | 1996-01-26 | 1999-01-19 | University Of Chicago | Rapid method to detect duplex formation in sequencing by hybridization methods |
| SE506700C2 (sv) * | 1996-05-31 | 1998-02-02 | Mikael Kubista | Sond och förfaranden för analys av nukleinsyra |
| US5730849A (en) * | 1996-09-30 | 1998-03-24 | Bio-Rad Laboratories, Inc. | High sensitivity dyes as stains for RNA bands in denaturing gels |
| US6290839B1 (en) | 1998-06-23 | 2001-09-18 | Clinical Micro Sensors, Inc. | Systems for electrophoretic transport and detection of analytes |
| US6761816B1 (en) | 1998-06-23 | 2004-07-13 | Clinical Micro Systems, Inc. | Printed circuit boards with monolayers and capture ligands |
| US7087148B1 (en) | 1998-06-23 | 2006-08-08 | Clinical Micro Sensors, Inc. | Binding acceleration techniques for the detection of analytes |
| US7312087B2 (en) * | 2000-01-11 | 2007-12-25 | Clinical Micro Sensors, Inc. | Devices and methods for biochip multiplexing |
| US6673568B1 (en) | 1999-10-25 | 2004-01-06 | Genprime, Inc. | Method and apparatus for prokaryotic and eukaryotic cell quantitation |
| US6787302B2 (en) * | 1999-10-25 | 2004-09-07 | Genprime, Inc. | Method and apparatus for prokaryotic and eukaryotic cell quantitation |
| AU2586001A (en) | 1999-12-21 | 2001-07-03 | Ortho-Clinical Diagnostics, Inc. | Detection of nucleic acids |
| US20020055134A1 (en) | 2000-07-24 | 2002-05-09 | Fleming James E. | Method and apparatus for viable and nonviable prokaryotic and eukaryotic cell quantitation |
| DE60222091T2 (de) * | 2001-01-08 | 2008-05-29 | Applera Corp., Bedford | Dendritische chemilumineszierende Substrate |
| JP4628594B2 (ja) * | 2001-06-25 | 2011-02-09 | 昭和電工株式会社 | 有機発光素子および発光材料 |
| US9261460B2 (en) * | 2002-03-12 | 2016-02-16 | Enzo Life Sciences, Inc. | Real-time nucleic acid detection processes and compositions |
| US7166478B2 (en) * | 2002-03-12 | 2007-01-23 | Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc. | Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses |
| US9353405B2 (en) | 2002-03-12 | 2016-05-31 | Enzo Life Sciences, Inc. | Optimized real time nucleic acid detection processes |
| GB0327524D0 (en) | 2003-11-26 | 2003-12-31 | Univ Glasgow | Heterocyclic aromatic compounds |
| WO2005080341A1 (en) * | 2004-02-13 | 2005-09-01 | Dsm Ip Assets B.V. | Ionic uv-a sunscreens and compositions containing them |
| EP2029726A4 (de) * | 2006-06-09 | 2010-07-28 | Univ Miami | Beurteilung der zellenzusammensetzung und fraktionelle durchführbarkeit und verwendungen davon |
| US7943320B2 (en) * | 2008-12-30 | 2011-05-17 | Canon U.S. Life Sciences, Inc. | Unsymmetrical cyanine dyes for high resolution nucleic acid melting analysis |
| WO2010110740A1 (en) * | 2009-03-25 | 2010-09-30 | Haiqing Gong | A fluidic apparatus and/or method for differentiating viable cells |
| WO2013189043A1 (zh) * | 2012-06-20 | 2013-12-27 | 大连理工大学 | 一类绿光荧光菁染料、制备方法及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4665184A (en) * | 1983-10-12 | 1987-05-12 | California Institute Of Technology | Bifunctional molecules having a DNA intercalator or DNA groove binder linked to ethylene diamine tetraacetic acid |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4912208A (en) | 1987-06-29 | 1990-03-27 | Abbott Laboratories | Fluorophores for encapsulation into liposomes |
| US5002883A (en) | 1987-10-30 | 1991-03-26 | Abbott Laboratories | Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents |
| US4994385A (en) | 1987-10-30 | 1991-02-19 | Abbott Laboratories | Heterobifunctional coupling agents |
| US5053520A (en) | 1988-09-22 | 1991-10-01 | Abbott Laboratories | Heterobifunctional maleimido containing coupling agents |
| US5063109A (en) | 1988-10-11 | 1991-11-05 | Abbott Laboratories | Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents |
| US5312921A (en) * | 1990-03-14 | 1994-05-17 | Regents Of The University Of California | Dyes designed for high sensitivity detection of double-stranded DNA |
| GB9122525D0 (en) * | 1991-10-23 | 1991-12-04 | Isis Innovation | Dna bis-intercalators |
-
1994
- 1994-06-23 AT AT94922010T patent/ATE264307T1/de not_active IP Right Cessation
- 1994-06-23 ES ES94922010T patent/ES2218527T3/es not_active Expired - Lifetime
- 1994-06-23 EP EP94922010A patent/EP0706515B1/de not_active Expired - Lifetime
- 1994-06-23 EP EP20040001486 patent/EP1411047A1/de not_active Ceased
- 1994-06-23 DE DE69435240T patent/DE69435240D1/de not_active Expired - Lifetime
- 1994-06-23 WO PCT/US1994/007130 patent/WO1995001341A1/en active IP Right Grant
- 1994-06-23 CA CA002162382A patent/CA2162382C/en not_active Expired - Fee Related
- 1994-06-23 EP EP07101154A patent/EP1792897B1/de not_active Expired - Lifetime
- 1994-06-23 JP JP50356595A patent/JP3856463B2/ja not_active Expired - Fee Related
- 1994-06-23 DE DE69433712T patent/DE69433712T2/de not_active Expired - Lifetime
- 1994-06-23 ES ES07101154T patent/ES2331813T3/es not_active Expired - Lifetime
- 1994-06-29 US US08/268,043 patent/US5582984A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1792897A3 (de) | 2007-06-13 |
| US5582984A (en) | 1996-12-10 |
| EP0706515B1 (de) | 2004-04-14 |
| EP1792897B1 (de) | 2009-09-16 |
| DE69433712D1 (de) | 2004-05-19 |
| EP1411047A1 (de) | 2004-04-21 |
| EP0706515A1 (de) | 1996-04-17 |
| WO1995001341A1 (en) | 1995-01-12 |
| ES2218527T3 (es) | 2004-11-16 |
| CA2162382C (en) | 2006-04-11 |
| DE69435240D1 (de) | 2009-10-29 |
| DE69433712T2 (de) | 2005-04-14 |
| EP1792897A2 (de) | 2007-06-06 |
| JP3856463B2 (ja) | 2006-12-13 |
| ES2331813T3 (es) | 2010-01-15 |
| CA2162382A1 (en) | 1995-01-12 |
| JPH09500871A (ja) | 1997-01-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE264307T1 (de) | Interkalatoren mit affinität für dna und ihre anwendung | |
| ES2065880T3 (es) | Proteina quimicamente modificada y obtencion de la misma. | |
| EA200000427A1 (ru) | Терапевтические применения хинолиновых производных | |
| DE69716461D1 (de) | Antithrombotische organische nitrate | |
| FR2434803A1 (fr) | Imides et bis-imides substitues a l'azote, utilisables comme corps intermediaires | |
| ATE196761T1 (de) | Inhibitoren retroviraler proteasen | |
| NO933376D0 (no) | Morfinan-derivater og medisinsk anvendelse derav | |
| AR038429A2 (es) | Compuestos 15-alquil-16-hidroxilo de marcfortina | |
| KR830005201A (ko) | 2-r_3rn-3-r_1rn-5-py-6-q-피리딘 또는 그의 산부가염의 제조방법 | |
| ES2149225T3 (es) | Preparacion de emplasto externo antiinflamatorio y analgesico. | |
| GB9324872D0 (en) | Pharmaceutical compounds | |
| DE69410193D1 (de) | Neue verbindungen mit blutplättchenaggregationshemmender aktivität | |
| PT74199A (de) | Neue trisubstituierte pyrimido<5,4-d>pyrimidine ihre herstel- lung und ihre verwendung als arzneimittel | |
| NO983691L (no) | Forbindelser tilh°rende amidiniumfamilien, farmas°ytiske preparater inneholdende disse samt anvendelse derav | |
| ATE85978T1 (de) | 2-quaternaer-pyridinalkylthio- oder pyridinalkenylthiosubstituierte carbapeneme, diese enthaltende zusammensetzungen und ihre zusammenstellungen mit dhp-inhibitoren. | |
| ATA152093A (de) | Neue guanidin- und amidinsalze von 7-amino-3-hydroxymethyl-3-cephem-4-carbonsäure | |
| TR199700631T1 (xx) | Herbisidler olarak ikame edilmi� 2-fenilpiridinler. | |
| ATE232732T1 (de) | 2',5'-phosphorthioat/phosphodiester- oligoadenylate und ihre antiviralen verwendungen | |
| ATE111947T1 (de) | Ferroelektrische chirale smektische flüssigkristallzusammensetzung und vorrichtung mit dieser zusammensetzung. | |
| IE44034L (en) | Pyrrolidone carboxylic acids. | |
| EP0226541A3 (de) | Lichthofschutzfarbstoffe | |
| AR240943A2 (es) | Nuevo compuesto agroquimico denominado "sustancia n 51262" procedimiento para prepararlo y composicion que lo comprende" | |
| ES550040A0 (es) | Un metodo para producir derivados de acido 2-(4-amino susti-tuido-3-oxo-2-isoxazolidinil)-5-oxo-2-tetrahidrofuran-carbo-xilico | |
| ATE24487T1 (de) | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. | |
| ATE104986T1 (de) | Aminsalze von 1,4,2-oxazaphospholidin-2-alkoxy-2oxid-4-essigs|uren. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0706515 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |