ATE114472T1 - System des typs ''einmal täglich'' zur gepulsten minocyclinabgabe. - Google Patents

System des typs ''einmal täglich'' zur gepulsten minocyclinabgabe.

Info

Publication number: ATE114472T1
Authority: AT; Austria
Prior art keywords: pulsed; delivery system; once daily; minocycline; minocycline delivery
Prior art date: 1989-09-21

Application number

AT90115881T

Other languages

English (en)

Inventor

Nitin Vadilal Sheth

Joseph James Valorose Jr

Keith Anthony Ellway

Madurai Gurusamy Ganesan

Kieran George Mooney

Jerry Bain Johnson

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-21

Filing date

1990-08-20

Publication date

1994-12-15

1990-08-20 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1994-12-15 Application granted granted Critical

1994-12-15 Publication of ATE114472T1 publication Critical patent/ATE114472T1/de

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT90115881T 1989-09-21 1990-08-20 System des typs ''einmal täglich'' zur gepulsten minocyclinabgabe. ATE114472T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US41070889A	1989-09-21	1989-09-21

Publications (1)

Publication Number	Publication Date
ATE114472T1 true ATE114472T1 (de)	1994-12-15

Family

ID=23625892

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90115881T ATE114472T1 (de)	1989-09-21	1990-08-20	System des typs ''einmal täglich'' zur gepulsten minocyclinabgabe.

Country Status (26)

Country	Link
US (2)	US5300304A (de)
EP (1)	EP0418565B1 (de)
JP (1)	JP3140764B2 (de)
KR (1)	KR100187950B1 (de)
CN (1)	CN1035039C (de)
AR (1)	AR244547A1 (de)
AT (1)	ATE114472T1 (de)
AU (1)	AU624998B2 (de)
CA (1)	CA2025703C (de)
CZ (1)	CZ283048B6 (de)
DD (1)	DD297558A5 (de)
DE (1)	DE69014513T2 (de)
DK (1)	DK0418565T3 (de)
ES (1)	ES2064564T3 (de)
FI (1)	FI96170C (de)
HK (1)	HK1000315A1 (de)
HU (1)	HU221804B1 (de)
IE (1)	IE66389B1 (de)
IL (1)	IL95423A (de)
NO (1)	NO177038C (de)
NZ (1)	NZ235319A (de)
PH (1)	PH30777A (de)
PL (1)	PL164770B1 (de)
PT (1)	PT95353B (de)
SK (1)	SK279358B6 (de)
ZA (1)	ZA907546B (de)

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ATE114472T1 (de) *	1989-09-21	1994-12-15	American Cyanamid Co	System des typs ''einmal täglich'' zur gepulsten minocyclinabgabe.
TW212139B (de) *	1991-04-15	1993-09-01	Yamanouchi Pharma Co Ltd
US5262173A (en) *	1992-03-02	1993-11-16	American Cyanamid Company	Pulsatile once-a-day delivery systems for minocycline
US5395626A (en) *	1994-03-23	1995-03-07	Ortho Pharmaceutical Corporation	Multilayered controlled release pharmaceutical dosage form
AU742231B2 (en) *	1994-03-23	2001-12-20	Ortho-Mcneil Pharmaceutical, Inc.	Multilayered controlled release pharmaceutical dosage form
IL109539A0 (en) *	1994-05-03	1994-08-26	Yissum Res Dev Co	Substained-release pharmaceutical system for the delivery of antioxidants
DE19715594A1 (de)	1997-04-15	1998-10-22	Bayer Ag	Analgetika-Kombination
US6120803A (en) *	1997-08-11	2000-09-19	Alza Corporation	Prolonged release active agent dosage form adapted for gastric retention
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US20030170181A1 (en) *	1999-04-06	2003-09-11	Midha Kamal K.	Method for preventing abuse of methylphenidate
JP2002541093A (ja) *	1999-04-06	2002-12-03	ファーマクエスト・リミテッド	ｄ−ｔｈｒｅｏ−メチルフェニデートおよび第２のＣＮＳ刺激薬のパルス性送達のための薬学的投薬形態
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US7220430B2 (en) *	2000-01-27	2007-05-22	Tanabe Seiyaku Co., Ltd.	Sustained-release preparation and process for producing the same
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US6958161B2 (en)	2002-04-12	2005-10-25	F H Faulding & Co Limited	Modified release coated drug preparation
US20040114368A1 (en) *	2002-12-13	2004-06-17	Shyu Shing Jy	Light device having rotatable or movable view
CA2894736C (en)	2003-04-07	2019-07-16	Supernus Pharmaceuticals, Inc.	Once daily formulations of tetracyclines
JP2006528190A (ja)	2003-07-21	2006-12-14	アドバンシスファーマスーティカルコーポレイション	抗生物質製剤、その使用法及び作成方法
AU2004258944B2 (en)	2003-07-21	2011-02-10	Shionogi, Inc.	Antibiotic product, use and formulation thereof
EP1648415A4 (de)	2003-07-21	2011-11-16	Middlebrook Pharmaceuticals Inc	Antibiotisches produkt, seine verwendung und formulierung
WO2005009416A1 (en) *	2003-07-24	2005-02-03	Ranbaxy Laboratories Limited	Modified release compositions for minocycline
EP1653925A1 (de)	2003-08-11	2006-05-10	Advancis Pharmaceutical Corporation	Robustes pellet
WO2005016278A2 (en)	2003-08-12	2005-02-24	Advancis Pharmaceuticals Corporation	Antibiotic product, use and formulation thereof
AU2004270170B2 (en)	2003-08-29	2011-01-27	Shionogi, Inc.	Antibiotic product, use and formulation thereof
WO2005027877A1 (en)	2003-09-15	2005-03-31	Advancis Pharmaceutical Corporation	Antibiotic product, use and formulation thereof
CN1332937C (zh) *	2003-12-31	2007-08-22	赤峰东陵药业有限责任公司	新四环霉素类衍生物
GB2414668B (en) *	2004-06-03	2009-07-29	Dexcel Ltd	Tetracycline modified release delivery system
US8715727B2 (en)	2004-07-02	2014-05-06	Shionogi Inc.	Tablet for pulsed delivery
US20060078621A1 (en) *	2004-10-13	2006-04-13	Wedinger Robert S	Method of providing customized drug delivery systems
US20080241235A1 (en) *	2007-04-02	2008-10-02	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
US20100215744A1 (en) *	2008-08-06	2010-08-26	Medicis Pharmaceutical Corporation	Hydroxypropyl Substitution Used to Regulate Dissolution of a Chemical
US20080242642A1 (en)	2007-04-02	2008-10-02	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
US8252776B2 (en)	2007-04-02	2012-08-28	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
US7919483B2 (en) *	2005-06-24	2011-04-05	Medicis Pharmaceutical Corporation	Method for the treatment of acne
US7541347B2 (en)	2007-04-02	2009-06-02	Medicis Pharmaceutical Coropration	Minocycline oral dosage forms for the treatment of acne
US9192615B2 (en)	2008-08-06	2015-11-24	Medicis Pharmaceutical Corporation	Method for the treatment of acne and certain dosage forms thereof
US8722650B1 (en)	2005-06-24	2014-05-13	Medicis Pharmaceutical Corporation	Extended-release minocycline dosage forms
US7544373B2 (en)	2007-04-02	2009-06-09	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
CN101247790A (zh) *	2005-08-26	2008-08-20	Bpsi控股公司	含有控释羟丙甲纤维素基质的药物组合物
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CN100512689C (zh) *	2006-09-28	2009-07-15	江南大学	一种用于降低卷烟烟气中焦油及自由基的添加剂及其添加方法
US20080241197A1 (en) *	2007-04-02	2008-10-02	Medicis Pharmaceutical Corporation	Minocycline dosage forms for the treatment of acne
WO2008121107A1 (en) *	2007-04-02	2008-10-09	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
US9561241B1 (en)	2011-06-28	2017-02-07	Medicis Pharmaceutical Corporation	Gastroretentive dosage forms for minocycline
TW201618783A (zh)	2014-08-07	2016-06-01	艾森塔製藥公司	以布魯頓(Bruton)氏酪胺酸激酶(BTK)佔據和BTK再合成速率為基礎之治療癌症、免疫和自體免疫疾病及發炎性疾病之方法
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1990
- 1990-08-20 AT AT90115881T patent/ATE114472T1/de not_active IP Right Cessation
- 1990-08-20 DE DE69014513T patent/DE69014513T2/de not_active Expired - Lifetime
- 1990-08-20 EP EP90115881A patent/EP0418565B1/de not_active Expired - Lifetime
- 1990-08-20 IL IL9542390A patent/IL95423A/en unknown
- 1990-08-20 DK DK90115881.6T patent/DK0418565T3/da active
- 1990-08-20 ES ES90115881T patent/ES2064564T3/es not_active Expired - Lifetime
- 1990-09-14 NZ NZ235319A patent/NZ235319A/xx unknown
- 1990-09-15 CN CN90107817A patent/CN1035039C/zh not_active Expired - Lifetime
- 1990-09-18 JP JP02246377A patent/JP3140764B2/ja not_active Expired - Lifetime
- 1990-09-19 CZ CS904559A patent/CZ283048B6/cs not_active IP Right Cessation
- 1990-09-19 PH PH41222A patent/PH30777A/en unknown
- 1990-09-19 SK SK4559-90A patent/SK279358B6/sk not_active IP Right Cessation
- 1990-09-19 CA CA002025703A patent/CA2025703C/en not_active Expired - Lifetime
- 1990-09-19 PT PT95353A patent/PT95353B/pt not_active IP Right Cessation
- 1990-09-20 ZA ZA907546A patent/ZA907546B/xx unknown
- 1990-09-20 NO NO904099A patent/NO177038C/no not_active IP Right Cessation
- 1990-09-20 AR AR90317918A patent/AR244547A1/es active
- 1990-09-20 AU AU63031/90A patent/AU624998B2/en not_active Expired
- 1990-09-20 FI FI904634A patent/FI96170C/fi active IP Right Grant
- 1990-09-20 PL PL90286971A patent/PL164770B1/pl unknown
- 1990-09-20 KR KR1019900014932A patent/KR100187950B1/ko not_active IP Right Cessation
- 1990-09-20 IE IE339890A patent/IE66389B1/en not_active IP Right Cessation
- 1990-09-21 HU HU9006006A patent/HU221804B1/hu not_active IP Right Cessation
- 1990-09-21 DD DD90344125A patent/DD297558A5/de unknown
1992
- 1992-05-27 US US07/892,383 patent/US5300304A/en not_active Expired - Lifetime
1993
- 1993-07-14 US US08/091,322 patent/US5413777A/en not_active Expired - Lifetime
1997
- 1997-10-04 HK HK97101885A patent/HK1000315A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI96170C (fi)	1996-05-27
HK1000315A1 (en)	1998-02-27
EP0418565A3 (en)	1991-09-25
PL286971A1 (en)	1992-01-27
US5300304A (en)	1994-04-05
DE69014513T2 (de)	1995-05-24
NZ235319A (en)	1993-03-26
EP0418565A2 (de)	1991-03-27
DK0418565T3 (da)	1995-01-23
HU906006D0 (en)	1991-03-28
NO177038C (no)	1995-07-12
DD297558A5 (de)	1992-01-16
NO177038B (no)	1995-04-03
IE66389B1 (en)	1995-12-27
HUT59314A (en)	1992-05-28
ZA907546B (en)	1991-07-31
IL95423A0 (en)	1991-06-30
CZ283048B6 (cs)	1997-12-17
DE69014513D1 (de)	1995-01-12
ES2064564T3 (es)	1995-02-01
AU6303190A (en)	1991-03-28
FI904634A0 (fi)	1990-09-20
CN1050320A (zh)	1991-04-03
CN1035039C (zh)	1997-06-04
JPH03112930A (ja)	1991-05-14
CZ455990A3 (en)	1997-08-13
KR100187950B1 (ko)	1999-06-01
PT95353A (pt)	1991-08-14
FI96170B (fi)	1996-02-15
NO904099L (no)	1991-03-22
JP3140764B2 (ja)	2001-03-05
CA2025703C (en)	2002-08-27
PL164770B1 (pl)	1994-10-31
NO904099D0 (no)	1990-09-20
HU221804B1 (hu)	2003-01-28
PH30777A (en)	1997-10-17
PT95353B (pt)	1998-05-29
AR244547A1 (es)	1993-11-30
AU624998B2 (en)	1992-06-25
US5413777A (en)	1995-05-09
CA2025703A1 (en)	1991-03-22
KR910005875A (ko)	1991-04-27
SK455990A3 (en)	1998-10-07
SK279358B6 (sk)	1998-10-07
IE903398A1 (en)	1991-04-10
IL95423A (en)	1994-11-11
EP0418565B1 (de)	1994-11-30

Publication	Publication Date	Title
ATE114472T1 (de)	1994-12-15	System des typs ''einmal täglich'' zur gepulsten minocyclinabgabe.
LT2185B (lt)	1993-10-15	5'-dezoksi-5-fluorcitidino dariniu gavimo budas
HU9302666D0 (en)	1994-01-28	Biological insecticide
DE69203249D1 (de)	1995-08-10	Vorrichtung zur Blutreinigung.
OA09194A (en)	1992-06-30	"Insecticidal treatment and compositions therefor".
KR950700707A (ko)	1995-02-20	치과용 치료시스템
AU5216690A (en)	1991-10-03	Periodontal disease treatment system
DE69202707D1 (de)	1995-07-06	Alkylmethylsiloxane zur Hautpflege.
DE58906881D1 (de)	1994-03-17	Gerät zur Zahnbehandlung.
IT1227849B (it)	1991-05-10	Composizione per l'igiene orale.
IT9047924A0 (it)	1990-05-08	Composizione per l'igiene orale.
DE69006899D1 (de)	1994-04-07	Mittel zur oralen Spülung.
FR2684540B1 (fr)	1996-05-03	Implant dentaire.
DE69021536D1 (de)	1995-09-14	Zahnimplantatsystem.
FR2720558B1 (fr)	1996-06-21	Système d'alimentation sécurisé.
IT1244668B (it)	1994-08-08	Impianto dentale endosseo.
GB2247602B (en)	1994-12-14	Horseshoe
DE59006623D1 (de)	1994-09-01	Vorrichtung zur Hubbegrenzung.
IT9048026A0 (it)	1990-06-04	Preparato farmaceutico e/o cosmetico.
DE69002821D1 (de)	1993-09-23	Zusammensetzung zur haarbehandlung.
KR940007408U (ko)	1994-04-15	메세지 전달 카드
GB2235637B (en)	1993-06-02	Horseshoe sprinlker
ES1023915Y (es)	1994-04-01	Implante dental.
ES1021400Y (es)	1993-05-16	Conjunto de higiene dental desechable.
ES1019967Y (es)	1993-03-01	Compresa higienica perfeccionada.

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