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ATE19519T1 - Dihydrothiazol-purine. - Google Patents

Dihydrothiazol-purine.

Info

Publication number
ATE19519T1
ATE19519T1 AT82107863T AT82107863T ATE19519T1 AT E19519 T1 ATE19519 T1 AT E19519T1 AT 82107863 T AT82107863 T AT 82107863T AT 82107863 T AT82107863 T AT 82107863T AT E19519 T1 ATE19519 T1 AT E19519T1
Authority
AT
Austria
Prior art keywords
lower alkyl
dihydrothiazole
purines
halogen
image
Prior art date
Application number
AT82107863T
Other languages
English (en)
Inventor
John Winthrop Hadden
Lionel Norton Simon
Alfredo Giner-Sorolla
Original Assignee
Newport Pharmaceuticals
Sloan Kettering Inst Cancer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newport Pharmaceuticals, Sloan Kettering Inst Cancer filed Critical Newport Pharmaceuticals
Application granted granted Critical
Publication of ATE19519T1 publication Critical patent/ATE19519T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT82107863T 1981-08-26 1982-08-26 Dihydrothiazol-purine. ATE19519T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/296,557 US4387226A (en) 1981-08-26 1981-08-26 Purine-dihydrothiazoles
EP82107863A EP0073490B1 (de) 1981-08-26 1982-08-26 Dihydrothiazol-purine

Publications (1)

Publication Number Publication Date
ATE19519T1 true ATE19519T1 (de) 1986-05-15

Family

ID=23142521

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82107863T ATE19519T1 (de) 1981-08-26 1982-08-26 Dihydrothiazol-purine.

Country Status (7)

Country Link
US (1) US4387226A (de)
EP (1) EP0073490B1 (de)
JP (1) JPS5843981A (de)
AT (1) ATE19519T1 (de)
AU (1) AU554372B2 (de)
DE (1) DE3270869D1 (de)
IN (1) IN158143B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614504A (en) * 1990-08-01 1997-03-25 The University Of South Florida Method of making inosine monophosphate derivatives and immunopotentiating uses thereof
US6057329A (en) * 1996-12-23 2000-05-02 Celltech Therapeutics Limited Fused polycyclic 2-aminopyrimidine derivatives
RU2660653C1 (ru) * 2017-05-29 2018-07-09 Федеральное государственное бюджетное образовательное учреждение высшего образования "Сибирский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СибГМУ Минздрава России) Способ получения 1,3-диметил-7-(пиперидин-1-илметил)-6,7-дигидротиазоло[3,2-f]пурин-2,4(1н,3н)-диона

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2592930A (en) * 1952-04-15 Method for preparing vitamin b
US2592931A (en) * 1952-04-15 Thiothiazolone derivatives
US3637684A (en) * 1968-01-05 1972-01-25 Pfizer Preparation of heterocycloimidazoles
US3770741A (en) * 1968-01-05 1973-11-06 Pfizer 1,3-dimethyl - 1,2,3,4 - tetrahydroheterocyclo(x,y-f)purine-2,4-diones and method for their preparation
BE755361A (fr) * 1969-08-28 1971-03-01 Newport Pharmaceuticals Derives de l'inosine
JPS516992A (ja) * 1974-07-03 1976-01-20 Dainippon Pharmaceutical Co Jihidorochiazoroadeninjudotaino seiho

Also Published As

Publication number Publication date
IN158143B (de) 1986-09-13
DE3270869D1 (de) 1986-06-05
AU554372B2 (en) 1986-08-21
AU1215183A (en) 1984-09-13
JPS5843981A (ja) 1983-03-14
JPH0435476B2 (de) 1992-06-11
EP0073490B1 (de) 1986-04-30
EP0073490A1 (de) 1983-03-09
US4387226A (en) 1983-06-07

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee