Nothing Special   »   [go: up one dir, main page]

ATE191501T1 - Verwendung von hepatocyten-wachstumsfaktoren zur herstellung eines vermehrungssystems für hematopoietische stammzellen - Google Patents

Verwendung von hepatocyten-wachstumsfaktoren zur herstellung eines vermehrungssystems für hematopoietische stammzellen

Info

Publication number
ATE191501T1
ATE191501T1 AT92916220T AT92916220T ATE191501T1 AT E191501 T1 ATE191501 T1 AT E191501T1 AT 92916220 T AT92916220 T AT 92916220T AT 92916220 T AT92916220 T AT 92916220T AT E191501 T1 ATE191501 T1 AT E191501T1
Authority
AT
Austria
Prior art keywords
hematopoietic stem
stem cell
proliferating
hepatocyte
produce
Prior art date
Application number
AT92916220T
Other languages
English (en)
Inventor
Atsushi Komiyama
Tatsutoshi Nakahata
Tetsuo Kubo
Ryuhei Tanaka
Genji Kawano
Tetsuo Sudo
Emiko Sano
Katsuaki Kojima
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Application granted granted Critical
Publication of ATE191501T1 publication Critical patent/ATE191501T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT92916220T 1991-07-26 1992-07-24 Verwendung von hepatocyten-wachstumsfaktoren zur herstellung eines vermehrungssystems für hematopoietische stammzellen ATE191501T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP18747091 1991-07-26
JP18748191 1991-07-26
PCT/JP1992/000949 WO1993003061A1 (en) 1991-07-26 1992-07-24 Hematopoietic stem cell multiplier

Publications (1)

Publication Number Publication Date
ATE191501T1 true ATE191501T1 (de) 2000-04-15

Family

ID=26504364

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92916220T ATE191501T1 (de) 1991-07-26 1992-07-24 Verwendung von hepatocyten-wachstumsfaktoren zur herstellung eines vermehrungssystems für hematopoietische stammzellen

Country Status (8)

Country Link
US (1) US6221359B1 (de)
EP (1) EP0550769B1 (de)
JP (1) JP3395181B2 (de)
AT (1) ATE191501T1 (de)
CA (1) CA2092542A1 (de)
DE (1) DE69230879T2 (de)
ES (1) ES2143990T3 (de)
WO (1) WO1993003061A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1271088B (it) * 1994-11-24 1997-05-26 Dompe Spa Uso di fattore di crescita degli epatociti per indurre la proliferazione e differenziazione di cellule emopoietiche
US5824789A (en) * 1995-06-07 1998-10-20 Systemix, Inc. Human growth factors, nucleotide sequence encoding growth factors, and method of use thereof
US5728581A (en) * 1995-06-07 1998-03-17 Systemix, Inc. Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein
WO2000007615A1 (fr) * 1998-08-05 2000-02-17 Sumitomo Pharmacueticals Co., Ltd. Preparations destinees a l'administration d'un facteur de croissance des hepatocytes
WO2004085616A2 (en) * 2003-03-24 2004-10-07 The Uab Research Foundation Regulation of self-renewal in stem cells
WO2004090121A2 (en) * 2003-04-08 2004-10-21 Yeda Research And Development Co. Ltd Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same
FR2853551B1 (fr) 2003-04-09 2006-08-04 Lab Francais Du Fractionnement Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee
WO2005023287A1 (ja) * 2003-09-03 2005-03-17 Kringle Pharma Inc. ヒト組換えｈｇｆを含有する皮膚潰瘍予防治癒剤
JP4716875B2 (ja) 2003-12-16 2011-07-06 敏一 中村 糖鎖欠損型肝細胞増殖因子
JP5093783B2 (ja) 2006-04-20 2012-12-12 クリングルファーマ株式会社 Ｈｇｆ前駆体蛋白質改変体及びその活性型蛋白質
CN103743906B (zh) * 2013-07-24 2015-05-20 北京大学人民医院 用于测定造血干细胞移植后患者骨髓微环境的试剂盒、系统及方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2564486B2 (ja) * 1986-07-14 1996-12-18 修治 橋本 肝細胞増殖因子
US5362716A (en) * 1989-12-27 1994-11-08 The United States Of America As Represented By The Department Of Health And Human Services Methods for stimulating hematopoietic progenitors using hepatocyte growth factor and lymphokines
KR0153009B1 (ko) * 1990-07-13 1998-10-15 카츄아 쇼노 티씨에프-ii의 아미노산 서열을 암호하는 dna를 함유한 플라스미드 형질전환세포 및 이것을 사용하여 생리 활성물질을 생산하는 방법

Also Published As

Publication number Publication date
US6221359B1 (en) 2001-04-24
ES2143990T3 (es) 2000-06-01
EP0550769A1 (de) 1993-07-14
WO1993003061A1 (en) 1993-02-18
EP0550769B1 (de) 2000-04-05
DE69230879T2 (de) 2000-08-03
CA2092542A1 (en) 1993-01-27
EP0550769A4 (de) 1994-04-27
JP3395181B2 (ja) 2003-04-07
DE69230879D1 (de) 2000-05-11

Similar Documents

Publication Publication Date Title
US6043089A (en) Skin culture and process for preparing the same
Myers et al. A hyaluronic acid membrane delivery system for cultured keratinocytes: clinical “take” rates in the porcine kerato-dermal model
DK0703978T3 (da) Medium til langtidsproliferation og -udvikling af celler
Olsson et al. Repigmentation of vitiligo by transplantation of cultured autologous melanocytes.
ATE358493T1 (de) Menschliche mesenchymale stammzellen aus peripherem blut
GB2137209A (en) Repair of cartilage and of bones
DE69928678D1 (de) Verwendung von wachstumsfaktoren und hormonen zur vermehrung menschlicher chondrozyten und knorpelgewebeherstellung
ATE191501T1 (de) Verwendung von hepatocyten-wachstumsfaktoren zur herstellung eines vermehrungssystems für hematopoietische stammzellen
CA2339182A1 (en) Improvement of cardiac function by mesenchymal stem cell transplantation
DE69533223D1 (de) Zusammensetzungen und verfahren zur stimulierung der proliferation und der differenzierung von menschlichen fetalen und erwachsenen pankreatischen zellen ex vivo
DE3751843D1 (de) Herstellung von körperorganen durch kontroliertes zellwachstum auf künstlicher matrix
EP0358506A3 (de) Dreidimensionales Zell- und Gewebekultursystem
ATE469654T1 (de) Verwendung des erythropoietins zur regeneration von lebergewebe
ATE288481T1 (de) Verwendung von collagenase in der zubereitung von neuralen stammzellkulturen
DE69028514D1 (de) Leukämiehemmender faktor aus vieharten und seine verwendung zur verbesserung der implantation und der entwicklung von embryonalen zellen
KR100201662B1 (en) Methods, compositions and devices for growing cells
McAuslan et al. Stimulation of endothelial cell proliferation by precursors of thymidylate
DK1071747T3 (da) Immortaliseret cellelinie afledt af normale, humane hudvæv
Dodson et al. In vitro comparison of aged and young osteogenic and hemopoietic bone marrow stem cells and their derivative colonies
Wong et al. Nuserum, a synthetic serum replacement, supports chondrogenesis of embryonic chick limb bud mesenchymal cells in micromass culture
AU6949994A (en) Animal model for hepatitis virus infection
Arase et al. Culture of human outer root sheath cells from plucked hair follicles in serum-free conditions
ATE225183T1 (de) Verwendung von hepatozyten-wachstumsfaktor zur induzierung der proliferation und differenzierung von hämatopoietischen zellen
EP0350887A2 (de) Serum-freies Medium und Verfahren zur Züchtung von Säugetierzellen
DE69837212D1 (de) Verfahren zur induzierung der osteoblastischen differenzierung der zellen des menschlichen extramedullären fettgewebes

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties