Nothing Special   »   [go: up one dir, main page]

ATE174066T1 - Hybridisation-ligitation-verfahren zum nachweis von spezifischen dns sequenzen - Google Patents

Hybridisation-ligitation-verfahren zum nachweis von spezifischen dns sequenzen

Info

Publication number
ATE174066T1
ATE174066T1 AT95912383T AT95912383T ATE174066T1 AT E174066 T1 ATE174066 T1 AT E174066T1 AT 95912383 T AT95912383 T AT 95912383T AT 95912383 T AT95912383 T AT 95912383T AT E174066 T1 ATE174066 T1 AT E174066T1
Authority
AT
Austria
Prior art keywords
hybridization
ligitation
dna sequences
specific dna
detecting specific
Prior art date
Application number
AT95912383T
Other languages
English (en)
Inventor
Richard A Martinelli
John C Arruda
Original Assignee
Ciba Corning Diagnostics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Corning Diagnostics Corp filed Critical Ciba Corning Diagnostics Corp
Application granted granted Critical
Publication of ATE174066T1 publication Critical patent/ATE174066T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6823Release of bound markers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4712Cystic fibrosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6862Ligase chain reaction [LCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT95912383T 1994-04-04 1995-04-03 Hybridisation-ligitation-verfahren zum nachweis von spezifischen dns sequenzen ATE174066T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22261394A 1994-04-04 1994-04-04

Publications (1)

Publication Number Publication Date
ATE174066T1 true ATE174066T1 (de) 1998-12-15

Family

ID=22832958

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95912383T ATE174066T1 (de) 1994-04-04 1995-04-03 Hybridisation-ligitation-verfahren zum nachweis von spezifischen dns sequenzen

Country Status (9)

Country Link
US (1) US5800994A (de)
EP (1) EP0754241B1 (de)
JP (1) JP3738910B2 (de)
AT (1) ATE174066T1 (de)
BR (1) BR9507343A (de)
CA (1) CA2186465A1 (de)
DE (1) DE69506393T2 (de)
PL (1) PL316611A1 (de)
WO (1) WO1995027078A1 (de)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6270961B1 (en) * 1987-04-01 2001-08-07 Hyseq, Inc. Methods and apparatus for DNA sequencing and DNA identification
US6401267B1 (en) 1993-09-27 2002-06-11 Radoje Drmanac Methods and compositions for efficient nucleic acid sequencing
USRE43097E1 (en) 1994-10-13 2012-01-10 Illumina, Inc. Massively parallel signature sequencing by ligation of encoded adaptors
GB9507238D0 (en) 1995-04-07 1995-05-31 Isis Innovation Detecting dna sequence variations
US5888731A (en) * 1995-08-30 1999-03-30 Visible Genetics Inc. Method for identification of mutations using ligation of multiple oligonucleotide probes
US6309824B1 (en) * 1997-01-16 2001-10-30 Hyseq, Inc. Methods for analyzing a target nucleic acid using immobilized heterogeneous mixtures of oligonucleotide probes
US6297006B1 (en) * 1997-01-16 2001-10-02 Hyseq, Inc. Methods for sequencing repetitive sequences and for determining the order of sequence subfragments
JP4294740B2 (ja) * 1997-05-23 2009-07-15 ソレクサ・インコーポレイテッド 分析物の系列的プロセシングのためのシステムおよび装置
CA2300940A1 (en) * 1997-08-15 1999-02-25 Hyseq, Inc. Methods and compositions for detection or quantification of nucleic acid species
CA2313483C (en) * 1997-12-12 2017-12-05 Digene Corporation Assessment of human papilloma virus-related disease
ATE423314T1 (de) 1998-06-24 2009-03-15 Illumina Inc Dekodierung von matrixartig-angeordneten sensoren durch mikropartikel
US5998175A (en) * 1998-07-24 1999-12-07 Lumigen, Inc. Methods of synthesizing and amplifying polynucleotides by ligation of multiple oligomers
US6232067B1 (en) * 1998-08-17 2001-05-15 The Perkin-Elmer Corporation Adapter directed expression analysis
US6180408B1 (en) 1998-08-21 2001-01-30 Washington University Fluorescence polarization in nucleic acid analysis
ATE234468T1 (de) 1998-09-18 2003-03-15 Massachusetts Inst Technology Biologische verwendungen von halbleitenden nanokristallen
AU7569600A (en) * 1999-05-20 2000-12-28 Illumina, Inc. Combinatorial decoding of random nucleic acid arrays
DE60026321D1 (de) * 1999-08-13 2006-04-27 Univ Yale New Haven Binär kodierte sequenzmarker
WO2001025481A1 (fr) 1999-10-04 2001-04-12 Olympus Optical Co., Ltd. Procede de detection d'acide nucleique
US6569685B1 (en) 1999-10-05 2003-05-27 The Molecular Sciences Institute, Inc. Protein fingerprint system and related methods
US7371584B2 (en) * 1999-10-15 2008-05-13 Wavesence, Inc. Multi-functional and configurable assay
US6136549A (en) * 1999-10-15 2000-10-24 Feistel; Christopher C. systems and methods for performing magnetic chromatography assays
US7390675B2 (en) * 1999-10-15 2008-06-24 Christopher Feistel Multi-functional and configurable assay
US6368801B1 (en) 2000-04-12 2002-04-09 Molecular Staging, Inc. Detection and amplification of RNA using target-mediated ligation of DNA by RNA ligase
CA2410950A1 (en) * 2000-05-30 2001-12-06 Hans-Michael Wenz Methods for detecting target nucleic acids using coupled ligation and amplification
US7439016B1 (en) 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
US7601497B2 (en) 2000-06-15 2009-10-13 Qiagen Gaithersburg, Inc. Detection of nucleic acids by target-specific hybrid capture method
US6562575B1 (en) 2000-06-26 2003-05-13 Epicentre Technologies Corporation Analyte-specific assays based on formation of a replicase substrate
JP4755755B2 (ja) * 2000-12-15 2011-08-24 独立行政法人産業技術総合研究所 複数検査多重化用懸濁液およびその懸濁液を用いた複数検査多重化方法
US20040266021A9 (en) * 2001-01-26 2004-12-30 Andras Guttman Multicapillary fraction collection system and method
US7018795B2 (en) * 2001-03-23 2006-03-28 Fuji Photo Film Co., Ltd. Hybridization probe and target nucleic acid detecting kit, target nucleic acid detecting apparatus and target nucleic acid detecting method using the same
US20020168667A1 (en) * 2001-03-23 2002-11-14 Fuji Photo Film Co., Ltd. Antigen detecting agent and antigen detecting kit, antigen detecting apparatus and antigen detecting method using the same
US20020168756A1 (en) * 2001-03-23 2002-11-14 Fuji Photo Film Co., Ltd. Particle size variable reactor
US7077982B2 (en) * 2001-03-23 2006-07-18 Fuji Photo Film Co., Ltd. Molecular electric wire, molecular electric wire circuit using the same and process for producing the molecular electric wire circuit
US20030003476A1 (en) * 2001-03-23 2003-01-02 Fuji Photo Film Co., Ltd. Waste water inspecting agent and waste water inspecting apparatus using the same
EP2196544A1 (de) * 2001-11-21 2010-06-16 Applied Biosystems, LLC Kit für Ligationsdetektionsreaktionen unter Verwendung von kodierten Markern
US7282355B2 (en) * 2002-03-13 2007-10-16 Syngenta Participations Ag Nucleic acid detection method
US20030179381A1 (en) * 2002-03-18 2003-09-25 Fuji Photo Film Co., Ltd. Sensor, color sensor and apparatus for inspection using the same
US20060105337A1 (en) * 2002-08-30 2006-05-18 Brian Warner Solid phase based nucleic acid assays combining high affinity and high specificity
US8394944B2 (en) * 2002-09-20 2013-03-12 Siemens Healthcare Diagnostics Inc. Dual-purpose primers and probes for providing enhanced hybridization assays by disruption of secondary structure formation
US20040235005A1 (en) * 2002-10-23 2004-11-25 Ernest Friedlander Methods and composition for detecting targets
JP4294946B2 (ja) * 2002-12-13 2009-07-15 富士フイルム株式会社 標的検出装置及び標的検出方法並びに標的検出用基材
US9487823B2 (en) 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
US7076127B2 (en) * 2003-01-14 2006-07-11 Fuji Photo Film Co., Ltd. Optical switch and safety apparatus using the same
US8043834B2 (en) 2003-03-31 2011-10-25 Qiagen Gmbh Universal reagents for rolling circle amplification and methods of use
WO2005001129A2 (en) * 2003-06-06 2005-01-06 Applera Corporation Mobility cassettes
US20060008823A1 (en) * 2004-05-12 2006-01-12 Kemp Jennifer T DNA profiling and SNP detection utilizing microarrays
EP1863908B1 (de) 2005-04-01 2010-11-17 Qiagen GmbH Reverse transkription und amplifikation von rna bei simultaner degradierung von dna
US20070020699A1 (en) * 2005-07-19 2007-01-25 Idexx Laboratories, Inc. Lateral flow assay and device using magnetic particles
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
TWI394839B (zh) 2008-10-27 2013-05-01 Qiagen Gaithersburg Inc 快速結果雜交捕捉法及系統
AU2010208311B2 (en) * 2009-01-28 2016-07-07 Qiagen Gaithersburg, Inc. Sequence-specific large volume sample preparation method and assay
JP5738278B2 (ja) 2009-05-01 2015-06-24 キアジェン ゲイサーズバーグ インコーポレイテッド 試料中のrnaスプライシング形態を検出するための非標的増幅法
AU2010291990B2 (en) 2009-09-14 2016-05-05 Qiagen Gaithersburg, Inc. Compositions and methods for recovery of nucleic acids or proteins from tissue samples fixed in cytology media
CA2787924A1 (en) * 2010-01-29 2011-08-04 Qiagen Gaithersburg, Inc. Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
JP2013517803A (ja) 2010-01-29 2013-05-20 キアジェン ゲイサーズバーグ インコーポレイテッド サンプル中のhpvの存在を決定および確認する方法
WO2011146629A2 (en) 2010-05-19 2011-11-24 Qiagen Gaithersburg Inc. Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
CN103597095B (zh) 2011-02-24 2016-08-17 奇亚根盖瑟斯堡股份有限公司 用于检测hpv核酸的材料和方法
US9447458B2 (en) 2011-11-16 2016-09-20 Canon U.S. Life Sciences, Inc. Detection of neighboring variants

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
US5242794A (en) * 1984-12-13 1993-09-07 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US4883750A (en) * 1984-12-13 1989-11-28 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US4925785A (en) * 1986-03-07 1990-05-15 Biotechnica Diagnostics, Inc. Nucleic acid hybridization assays
US5312910A (en) * 1987-05-26 1994-05-17 Monsanto Company Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthase
US4988617A (en) * 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
CA1341584C (en) * 1988-04-06 2008-11-18 Bruce Wallace Method of amplifying and detecting nucleic acid sequences
AU3539089A (en) * 1988-04-08 1989-11-03 Salk Institute For Biological Studies, The Ligase-based amplification method
US5241070A (en) * 1988-09-26 1993-08-31 Ciba Corning Diagnostics Corp. Nucleophilic polysubstituted aryl acridinium esters and uses thereof
ATE459709T1 (de) * 1990-05-03 2010-03-15 Cornell Res Foundation Inc Hitzestabiles ligase enthaltendes dns- amplifikationssystem zur bestimmung von genetischen krankheiten
CA2049879A1 (en) * 1990-08-30 1992-03-01 Keith C. Backman Controlled initial target-dependent production of templates for ligase chain reaction
CA2046713A1 (en) * 1990-10-16 1992-04-17 Richard M. Martinelli Amplification of midivariant dna templates
NZ245242A (en) * 1992-01-17 1994-12-22 Pioneer Hi Bred Int Identifying variations between organisms by detecting polymorphisms in single sequence repeats
WO1993020236A1 (en) * 1992-04-03 1993-10-14 Applied Biosystems, Inc. Probe composition and method
AU4848393A (en) * 1992-09-25 1994-04-26 Abbott Laboratories Ligase chain reaction method for detecting small mutations

Also Published As

Publication number Publication date
EP0754241B1 (de) 1998-12-02
US5800994A (en) 1998-09-01
AU1958595A (en) 1995-10-23
PL316611A1 (en) 1997-01-20
DE69506393T2 (de) 1999-07-01
BR9507343A (pt) 1997-09-16
DE69506393D1 (de) 1999-01-14
CA2186465A1 (en) 1995-10-12
WO1995027078A1 (en) 1995-10-12
EP0754241A1 (de) 1997-01-22
JPH09510878A (ja) 1997-11-04
AU684915B2 (en) 1998-01-08
JP3738910B2 (ja) 2006-01-25

Similar Documents

Publication Publication Date Title
DE69506393D1 (de) Hybridisation-ligitation-verfahren zum nachweis von spezifischen dns sequenzen
EP0139489A3 (de) Sandwichhybridisierungsverfahren zum Nachweis von Nukleinsäuren
AU2001282920A1 (en) Methods for detecting and assaying nucleic acid sequences
WO2001094632A3 (en) Highly sensitive gene detection and localization using in situ branched-dna hybridization
DE69603723D1 (de) Verfahren zum nachweis von nukleinsäuren
GB2375539A (en) Human genome-derived single exon nucleic acid probes useful for analysis of gene expression in human adult liver
ATE206764T1 (de) Verfahren zum sensitiven nachweis von nukleinsäuren
WO1999061665A3 (en) Solution hybridization of nucleic acids with antisense probes having modified backbones
DE69231693D1 (de) Hbv amplifizierungssonden zur verwendung in hybridisierungssandwichassay in der lösungsphase
EP0875584A3 (de) Nukleinsäuretestverfahren
NZ306051A (en) Testing using electrochemiluminescence
FI950836A (fi) Väärien negatiivien tulosten eliminointi nukleiinihapon toteamisessa
MXPA03001879A (es) Metodo y sistema para detectar acidos nucleicos.
ATE336591T1 (de) Nachweisverfahren für kurze sequenzvarianten
DK0975800T3 (da) Analyse af nukleotider i opløsning under anvendelse af PNA-prober
AU4663997A (en) Detection and identification of non-polio enteroviruses
WO1998044157A3 (en) Methods for identifying variations in polynucleotide sequences
DE69709804D1 (de) Nachweis von nukleotidsequenzen durch signalamplifizierung
ATE253127T1 (de) Sonde zur anwendung in der analyse von nukleinsaüren und verfahren der detektion basierend auf excimer-fluoreszenz
DE69837155D1 (de) Verfahren zum nachweiss von antikörpern in einer probe
MX9604607A (es) Ensayos de hibridacion-ligacion para la deteccion de secuencias de acido nucleico especificas.
DE69632826D1 (de) Nukleinsaeure erkennung von hepatitis gb virus
EP0677589A3 (de) Verfahren, Testelement und Testsatz zum halbquantitativen Nachweis von Nukleinsäure
ATE258601T1 (de) Sonden zum nachweis von durch streptococcus pyogenes hervorgerufenen infektionen
DE69524199D1 (de) Primer und sonden zur amplifizierung und zum nachweis von cmv nukleinsäure

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties